PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between LIG1 and WRN

The interaction score between LIG1 and WRN is 10.80.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between LIG1 and WRN = 0.68

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

7.78E-3

Orthology

Organism	LIG1 Orthologue		WRN Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
worm	Q27474	1	Q19546	1
fly	Q960P4	1	Q9VE86	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: LIG1

PTM	Residue	Reference
Phosphorylation	66	PubMed, HPRD
Phosphorylation	76	PubMed, HPRD
Phosphorylation	141	PubMed, HPRD
Phosphorylation	195	PubMed, HPRD
Phosphorylation	911	PubMed, HPRD
Phosphoserine	66	HPRD
Phosphoserine	76	HPRD
Phosphoserine	141	HPRD
Phosphoserine	911	HPRD
Phosphothreonine	195	HPRD

Protein: WRN

PTM	Residue	Reference
Phosphorylation	1141	PubMed, HPRD
Phosphorylation	1292	PubMed, HPRD

Localisation

Protein: LIG1

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Protein: WRN

Localisation	Reference
Nucleus	HPRD
Nucleolus	HPRD

Transitive Score

The common interactors between LIG1 and WRN that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andWRN. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and WRN has 868 interactors of which there are 671 common interactors.

Common Interactor	Name of Common Interactor	Score for LIG1-Interactor (?)	Score for WRN-Interactor (?)
PCNA	PCNA: Proliferating cell nuclear antigen	73.00	0.763
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.704	0.284
ESPL1	N/A	0.307	0.070
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.307	0.070
DNMT1	DNMT1, AIM, DNMT: DNA	0.307	0.070
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.307	0.070
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.307	0.144
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.307	0.210
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.307	0.210
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.276	0.078
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.276	0.078
KIF11	N/A	0.276	0.078
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.276	0.129
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.276	0.078
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.276	0.763
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.276	0.063
MCM3	MCM3: DNA replication licensing factor MCM3	0.276	0.461
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.276	0.233
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.276	0.129
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.461
CBX3	CBX3: Chromobox protein homolog 3	0.276	0.078
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.276	0.233
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.251	0.032
TCOF1	N/A	0.144	0.052
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.144	0.087
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.070
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.144	0.087
MKI67	MKI67: Antigen KI-67	0.144	0.087
SET	SET: Protein SET	0.144	0.052
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.144	0.155
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.144	0.070
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.144	0.155
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.144	0.070
UBAP2	N/A	0.144	0.070
RBM14	RBM14, SIP: RNA-binding protein 14	0.144	0.155
CENPA	CENPA: Histone H3-like centromeric protein A	0.144	0.070
PTMA	N/A	0.144	0.070
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.144	0.087
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.141	0.040
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.141	0.040
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.139	0.029
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.129	0.233
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.129	0.063
SSB	SSB: Lupus La protein	0.129	0.233
MYBL2	MYBL2, BMYB: Myb-related protein B	0.129	0.372
CDK4	CDK4: Cell division protein kinase 4	0.129	0.078
TIAL1	TIAL1: Nucleolysin TIAR	0.129	0.188
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.129	0.188
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.129	0.063
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.078
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.129	0.188
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.118
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.129	0.233
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.129	0.046
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.129	0.063
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.129	0.129
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.118
CDK2	CDK2: Cell division protein kinase 2	0.129	0.078
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.078
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.129	0.188
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.129	0.078
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.129	0.063
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.129	0.129
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.063
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.129	0.078
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.129	0.078
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.063
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.188
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.129	0.233
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.129	0.275
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.129	0.063
WEE1	WEE1: Wee1-like protein kinase	0.129	0.063
NOL1	N/A	0.129	0.063
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.129	0.233
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.063
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.063
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.129	0.461
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.129	0.188
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.129	0.372
CCNB1	Cyclin B1	0.129	0.078
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.129	0.063
H2AFX	H2AFX, H2AX: Histone H2A.x	0.129	0.078
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.129	0.118
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.129	0.139
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.129	0.139
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.146
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.129	0.078
POLA2	POLA2: DNA polymerase subunit alpha B	0.129	0.063
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.129	0.063
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.129	0.461
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.461
UNG	N/A	0.129	0.078
NUP153	N/A	0.129	0.078
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.188
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.188
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.275
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.129	0.372
ROCK1	ROCK1: Rho-associated protein kinase 1	0.127	0.026
PLEK	PLEK, P47: Pleckstrin	0.127	0.026
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.114	0.029
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.155
NBN	NBN, NBS, NBS1, P95: Nibrin	0.087	0.155
ABCF1	N/A	0.087	0.0425
KIF23	N/A	0.087	0.070
RB1	RB1: Retinoblastoma-associated protein	0.087	0.070
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.210
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.087	0.307
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.416
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.087	0.0425
DDX21	DDX21: Nucleolar RNA helicase 2	0.087	0.210
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.087	0.052
TRRAP	N/A	0.087	0.0425
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.087	0.0425
GNB2L1	Lung cancer oncogene 7	0.087	0.080
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.155
TOP2B	N/A	0.087	0.052
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.086	0.029
DOK1	DOK1: Docking protein 1	0.086	0.029
NF2	NF2, SCH: Merlin	0.083	0.028
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.078	0.038
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.078	0.139
MTA1	MTA1: Metastasis-associated protein MTA1	0.078	0.275
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.078	0.139
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.078	0.139
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.063
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.063
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.078	0.087
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.078	0.139
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.078	0.046
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.114
WBSCR20A	N/A	0.078	0.038
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.078	0.260
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.038
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.078	0.046
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.139
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.078
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.078	0.275
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.078	0.372
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.078	0.078
TP53	TP53, P53: Cellular tumor antigen p53	0.078	0.139
PHF10	N/A	0.078	0.078
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.188
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.078	0.063
PPP1R8	N/A	0.078	0.046
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.087
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.078	0.046
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.078	0.275
HDAC2	HDAC2: Histone deacetylase 2	0.078	0.233
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.139
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.078	0.063
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.063
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.188
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.078	0.225
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	14.40
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.078	0.063
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.078	0.063
MDN1	MDN1, KIAA0301: Midasin	0.078	0.114
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.046
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.046
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.078	0.139
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.075	0.025
ELMO1	N/A	0.075	0.075
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.075	0.025
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.074	0.0446
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.036
FUBP1	N/A	0.074	0.027
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.070
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.155
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.032
KIAA0853	N/A	0.070	0.070
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.070	0.096
CHUK	N/A	0.070	0.052
SREBF2	N/A	0.070	0.032
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.070	0.127
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.070	0.032
ELF1	ELF1: ETS-related transcription factor Elf-1	0.070	0.032
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.052
RBM6	RBM6, DEF3: RNA-binding protein 6	0.070	0.096
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.052
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.155
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.070	0.155
ARFGAP1	N/A	0.070	0.052
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.070	0.307
API5	N/A	0.070	0.070
IRF3	IRF3: Interferon regulatory factor 3	0.070	0.026
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.070	0.191
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.052
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.0425
MYB	MYB: Myb proto-oncogene protein	0.070	0.416
TGIF2	TGIF2: Homeobox protein TGIF2	0.070	0.127
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.069	0.049
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.067	0.041
XPO1	XPO1, CRM1: Exportin-1	0.066	0.137
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.066	0.040
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.032
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.066	0.066
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.066	0.032
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.032
HSPD1		0.066	0.032
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.066	0.040
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.032
TK1	TK1: Thymidine kinase, cytosolic	0.066	0.040
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.032
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.066	0.040
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.066	0.040
CTPS	CTPS: CTP synthase 1	0.066	0.032
CDC23	CDC23: Cell division cycle protein 23 homolog	0.066	0.040
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.040
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.063	0.275
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.038
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.063	0.063
CUL5	CUL5, VACM1: Cullin-5	0.063	0.046
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.063	0.171
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.063	0.114
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.063	0.086
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.188
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.114
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.188
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.118
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.114
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.063	0.129
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.063	0.038
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.029
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.063	0.087
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.063	0.038
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.063	0.063
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.063	0.114
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.046
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.038
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.225
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.063	0.139
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.063	0.046
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.029
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.139
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.046
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.063	0.139
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.063	0.063
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.063	0.118
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.139
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.063	0.114
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.063	0.063
SAPS3	N/A	0.063	0.046
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.114
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.038
GAB1	GAB1: GRB2-associated-binding protein 1	0.062	0.032
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.061	0.027
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.052	0.0425
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.052	0.251
HIVEP1	N/A	0.052	0.155
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.052	0.0425
AFF1	N/A	0.052	0.0425
NCOA3	N/A	0.052	0.026
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.052	0.155
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.052	0.307
IFI16	N/A	0.052	0.026
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.155
SMARCC2	N/A	0.052	0.032
SP100	N/A	0.052	0.032
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.052	0.032
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.052	0.026
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.052	0.127
XRCC1	XRCC1: DNA-repair protein XRCC1	0.052	0.155
EMD	EMD, EDMD, STA: Emerin	0.052	0.0425
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.032
SNRPA	SNRPA: U1 small nuclear ribonucleoprotein A	0.048	0.037
EZH2	EZH2: Enhancer of zeste homolog 2	0.0479	0.143
ANAPC1	ANAPC1, TSG24: Anaphase-promoting complex subunit 1	0.0479	0.061
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.047	0.025
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.114
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.046	0.046
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.046	0.086
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.046	0.029
SYMPK	SYMPK, SPK: Symplekin	0.046	0.071
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.114
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.046	0.086
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.046	0.038
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.046	0.038
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.114
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.029
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.046	0.038
SRF	SRF: Serum response factor	0.046	0.046
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.046	0.029
EP300	N/A	0.046	0.046
COPB2	COPB2: Coatomer subunit beta'	0.046	0.087
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.046	0.114
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.046	0.029
CDK7	CDK7, MO15: Cell division protein kinase 7	0.046	0.029
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.046	0.038
WDR79	N/A	0.046	0.038
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.046	0.029
SP3	SP3: Transcription factor Sp3	0.046	0.139
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.046	0.046
CSDA	CSDA, DBPA: DNA-binding protein A	0.046	0.275
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.046	0.233
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.046
KIAA1012	KIAA1012: Protein TRS85 homolog	0.046	0.029
DIAPH1	Diaphanous 1	0.046	0.029
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.046	0.086
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.046	0.046
RPS6KB1	N/A	0.046	0.046
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.046	0.086
RUNX1	N/A	0.046	0.046
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.046	0.171
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.038
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.046	0.114
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.046	0.029
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.046	0.225
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.038
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.046	0.038
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.063
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.046	0.225
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.046	0.029
KLHDC4	N/A	0.046	0.038
RBM7		0.046	0.114
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.029
CUL4B	N/A	0.046	0.029
FKBP4	FKBP4: FK506-binding protein 4	0.046	0.046
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.046	0.139
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.046	0.029
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.046	0.029
TAL1	TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1	0.046	0.118
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.046	0.077
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.0446	0.036
PHB2	PHB2, BAP, REA: Prohibitin-2	0.0446	0.027
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.0446	0.027
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.0425	0.0425
GTF2F2	N/A	0.0425	0.052
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.026
COIL	COIL, CLN80: Coilin	0.0425	0.032
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.0425	0.127
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.0425	0.026
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.0425	0.127
H1FX	H1FX: Histone H1x	0.0425	0.0425
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.0425	0.191
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.0425	0.026
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.0425	0.191
ERG	ERG: Transcriptional regulator ERG	0.0425	0.032
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.096
STK16	N/A	0.0425	0.032
WDR1	N/A	0.0425	0.048
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.0425	0.127
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.0425	0.052
NFATC1	N/A	0.0425	0.026
FRG1	FRG1: Protein FRG1	0.040	0.032
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.032
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.032
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.040	0.0818
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.040	0.032
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.032
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.032
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.040	0.032
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.040	0.181
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.040	0.111
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.040	0.032
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.040	0.040
HSP90AA1	Hsp89-alpha-delta-N	0.040	0.040
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.040	0.032
THOC1	THOC1, HPR1: THO complex subunit 1	0.040	0.040
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.040	0.137
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.040	0.032
BRPF1	BRPF1, BR140: Peregrin	0.038	0.086
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.038	0.029
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.038	0.029
SOX4	SOX4: Transcription factor SOX-4	0.038	0.038
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.038	0.086
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.038	0.086
ZNF551	N/A	0.038	0.114
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.069
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.038	0.029
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.038	0.038
MAFG	MAFG: Transcription factor MafG	0.038	0.046
PCAF	PCAF: Histone acetyltransferase PCAF	0.038	0.038
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.029
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.038	0.029
HDAC6	HDAC6, JM21: Histone deacetylase 6	0.038	0.086
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.038	0.038
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.069
METTL1	METTL1, C12orf1: tRNA	0.038	0.029
COPA	COPA: Coatomer subunit alpha	0.038	0.071
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.038	0.038
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.086
CDK6	CDK6: Cell division protein kinase 6	0.038	0.038
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.029
FZR1	N/A	0.038	0.046
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.038	0.029
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.038	0.029
TSC1	TSC1, KIAA0243, TSC: Hamartin	0.038	0.029
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.029
SATB1	SATB1: DNA-binding protein SATB1	0.038	0.056
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.038	0.029
SEC31L1	N/A	0.038	0.071
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.038
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.038	0.086
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.038	0.029
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.038	0.086
YWHAQ	YWHAQ: 14-3-3 protein theta	0.036	0.091
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.036	0.027
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.091
IPO7	IPO7: Uncharacterized protein IPO7	0.036	0.124
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.096
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.032	0.077
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.026
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.032	0.026
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.032
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.032
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.032	0.026
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.032	0.026
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.048
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.096
GTF3C1	N/A	0.032	0.026
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.032	0.0425
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.032	0.077
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.032	0.0425
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.032	0.032
MECP2	MECP2: Methyl-CpG-binding protein 2	0.032	0.026
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.032
XRCC4	N/A	0.032	0.032
PPARBP	N/A	0.032	0.032
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.032	0.032
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.032	0.032
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.032	0.0818
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.032	0.051
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.032	0.0818
EIF4G3	EIF4G3: Eukaryotic translation initiation factor 4 gamma 3	0.029	0.136
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.029	0.056
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.029	0.029
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.029	0.054
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.029	0.069
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.029	0.069
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.029	0.038
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.038
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.029
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.029	0.029
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.029	0.029
GATA2	N/A	0.029	0.038
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.029	0.035
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.029	0.038
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.029	0.069
POLB	POLB: DNA polymerase beta	0.029	0.026
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.127
CORO1C	CORO1C, CRNN4: Coronin-1C	0.029	0.054
GSK3B	N/A	0.029	0.029
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.029	0.029
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.029	0.086
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.069
WDR44	WDR44: WD repeat-containing protein 44	0.029	0.029
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.029	0.086
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.029	0.096
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.029	0.043
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.043
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.165
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
C20orf18	N/A	0.028	0.028
UHRF1		0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.165
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.083
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.083
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
C13orf8	N/A	0.028	0.028
PPEF1	N/A	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.083
MAPKAPK5	N/A	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.083
ZNF265	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
HDAC8	N/A	0.028	0.083
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.083
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
SNRPB	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.083
DSP	DSP: Desmoplakin	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
WDR54	N/A	0.028	0.052
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.083
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.083
CORO6	N/A	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
IRF7	N/A	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.052
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
BID	BID: BH3-interacting domain death agonist	0.028	0.028
MAPK15	N/A	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.083
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.028	0.028
PHLDB2	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.083
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.083
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.083
HES6	HES6: Transcription cofactor HES-6	0.028	0.028
KIF1B	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.165
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
HD	HD, IT15: Huntingtin	0.027	0.057
ERF	ERF: ETS domain-containing transcription factor ERF	0.026	0.032
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.026	0.026
GRLF1	N/A	0.026	0.026
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.032
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.032
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.096
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.026	0.096
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.026	0.026
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.075
RBL1	RBL1: Retinoblastoma-like protein 1	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.075
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.075
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.075
BCOR	N/A	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.047
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.075
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.075
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
TCEA1	N/A	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.075
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
CCNT2	CCNT2: Cyclin-T2	0.025	0.025
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.075
NUP98	N/A	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.148
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
KCTD1		0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.075
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CAMKK1	N/A	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
FLJ23436	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.075
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.148
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.075
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.075
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
CAMK2A	N/A	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.148
NIPBL	N/A	0.025	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.075
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
GRK6	N/A	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.075
C20orf77	N/A	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.075
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
HDAC7A	N/A	0.025	0.075
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.075
DIDO1	N/A	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.047
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.047
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.075
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.075
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
GIT2	N/A	0.025	0.025
EEF2K	EEF2K: Elongation factor 2 kinase	0.025	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
SOX8	SOX8: Transcription factor SOX-8	0.025	0.025
ATXN2L	N/A	0.025	0.025
HTATIP	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.083
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.028
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
SEC13L1	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.047
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.047
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
BRD4	N/A	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.148
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.075
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.148
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.148
RNF20		0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.075
NES	N/A	0.025	0.028
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.025
SON		0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.025
PRKCB1	N/A	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.075
GMNN	GMNN: Geminin	0.025	0.025

0.347

Total Score

10.80