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Evidence of Interaction Between TP53 and CHEK2

The interaction score between TP53 and CHEK2 is 2.99.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismTP53 OrthologueCHEK2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly Q8IH92 0.16 O61267 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in TP53 and CHEK2:
Domains in TP53Domains in CHEK2
IPR008967 p53-like transcription factor, DNA-binding
IPR002117 p53 tumor antigen
IPR010991 p53, tetramerisation
IPR011615 P53_DNA_bd.
IPR012346 P53_RUNT_DNA_bd.
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR008271 Serine/threonine protein kinase, active site
IPR000253 Forkhead-associated (FHA)

The Chi square scores for co-occurrence of domains that are present in TP53 and CHEK2 are listed below.

Domain 1Domain 2Chi Square
IPR012346 P53_RUNT_DNA_bd. IPR008271 Serine/threonine protein kinase, active site 4.60701
IPR011615 P53_DNA_bd. IPR008271 Serine/threonine protein kinase, active site 4.60701
IPR010991 p53, tetramerisation IPR008271 Serine/threonine protein kinase, active site 4.60701
IPR002117 p53 tumor antigen IPR008271 Serine/threonine protein kinase, active site 4.60701
IPR012346 P53_RUNT_DNA_bd. IPR002290 Serine/threonine protein kinase 3.23646
IPR011615 P53_DNA_bd. IPR002290 Serine/threonine protein kinase 3.23646
IPR010991 p53, tetramerisation IPR002290 Serine/threonine protein kinase 3.23646
IPR002117 p53 tumor antigen IPR002290 Serine/threonine protein kinase 3.23646
IPR008967 p53-like transcription factor, DNA-binding IPR002290 Serine/threonine protein kinase 1.43889
IPR008967 p53-like transcription factor, DNA-binding IPR008271 Serine/threonine protein kinase, active site 0.974716
IPR008967 p53-like transcription factor, DNA-binding IPR000719 Protein kinase 0.163761
IPR012346 P53_RUNT_DNA_bd. IPR000719 Protein kinase 0.000322699
IPR011615 P53_DNA_bd. IPR000719 Protein kinase 0.000322699
IPR010991 p53, tetramerisation IPR000719 Protein kinase 0.000322699
IPR002117 p53 tumor antigen IPR000719 Protein kinase 0.000322699

The background colour of the table refers to:

  • Blue Domain is only present in TP53
  • Yellow Domain is only present in CHEK2
  • Green Domain is present in both TP53 and CHEK2

 0.028
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: CHEK2

PTMResidueReference
Phosphorylation 19 PubMed, HPRD
Phosphorylation 26 PubMed, HPRD
Phosphorylation 28 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 35 PubMed, HPRD
Phosphorylation 50 PubMed, HPRD
Phosphorylation 68 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 430 PubMed, HPRD
Phosphorylation 559 PubMed, HPRD
Phosphothreonine 68 PubMed, HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: CHEK2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and CHEK2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andCHEK2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and CHEK2 has 1372 interactors of which there are 872 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for CHEK2-Interactor (?)
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.77 0.028
H2AFX H2AFX, H2AX: Histone H2A.x 4.27 6.64
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 2.54 6.64
HIST1H1E HIST1H1E, H1F4: Histone H1.4 2.08 3.97
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.025
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 1.58 0.075
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 1.58 1.33
HIST1H1B HIST1H1B, H1F5: Histone H1.5 1.26 3.97
PGR PGR, NR3C3: Progesterone receptor 1.00 0.028
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 0.187
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.902 0.025
HIST1H4A HIST1H4A, H4/A, HIST1H4B, H4/I, H4/G, HIST1H4D, H4/B, H4/J, HIST1H4F, HIST4H4, H 0.902 6.64
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.025
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.025
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.025
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.704 0.025
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.028
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.541 0.049
SP100 N/A 0.525 0.028
MCM3 MCM3: DNA replication licensing factor MCM3 0.515 0.047
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.503 0.044
SREBF2 N/A 0.475 0.028
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.025
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.052
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.028
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.165
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.083
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.028
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 0.075
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.028
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.083
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.052
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.425 0.047
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.025
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.025
CCNB1 Cyclin B1 0.385 0.148
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.025
SP3 SP3: Transcription factor Sp3 0.347 0.025
SRF SRF: Serum response factor 0.344 0.025
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.318 0.075
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.290 0.075
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.284 0.075
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.025
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.025
POLA2 POLA2: DNA polymerase subunit alpha B 0.276 0.025
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.276 0.025
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.276 0.025
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.276 0.025
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.025
CENPA CENPA: Histone H3-like centromeric protein A 0.269 0.028
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.028
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.260 0.075
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.028
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.028
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.254 0.025
EP300 N/A 0.254 0.025
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.253 0.049
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.245 0.044
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.241 0.025
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.241 0.047
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.241 0.025
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.075
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.075
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.233 0.148
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.025
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.025
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.025
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.227 0.044
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.216 0.025
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.216 0.025
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.083
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.028
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.028
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.025
RB1 RB1: Retinoblastoma-associated protein 0.210 0.083
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.208 0.025
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.025
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.188 0.025
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.075
CXorf9 N/A 0.188 0.025
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.025
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.188 0.025
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 39.20
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.025
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.075
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.188 0.025
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.187 0.148
MYB MYB: Myb proto-oncogene protein 0.176 0.083
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.172 0.047
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.172 0.047
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.162 0.049
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.156 0.052
TP73 TP73, P73: Tumor protein p73 0.156 0.028
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.155 0.165
ZNF267 ZNF267: Zinc finger protein 267 0.155 0.028
ERF ERF: ETS domain-containing transcription factor ERF 0.155 0.083
XRCC1 XRCC1: DNA-repair protein XRCC1 0.155 0.083
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.028
MITF MITF: Microphthalmia-associated transcription factor 0.152 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.152 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.152 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.165
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.146 0.025
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.146 0.075
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.146 0.025
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.146 0.075
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.146 0.075
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.144 0.052
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.165
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.028
ESPL1 N/A 0.144 0.028
PTMA N/A 0.144 0.052
ABCF1 N/A 0.144 0.028
MKI67 MKI67: Antigen KI-67 0.144 0.052
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.028
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.141 0.098
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.141 0.098
SAT SAT1, SAT: Diamine acetyltransferase 1 0.140 0.028
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.140 0.025
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.075
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.139 0.025
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.139 0.025
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.025
COPE COPE: Coatomer subunit epsilon 0.139 0.075
RELA RELA, NFKB3: Transcription factor p65 0.139 0.075
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.025
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.075
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.139 0.025
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.139 0.075
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.139 0.025
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.075
CDC23 CDC23: Cell division cycle protein 23 homolog 0.137 0.044
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.137 0.044
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.148
LMNA LMNA, LMN1: Lamin-A/C 0.137 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.137 0.025
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.132 0.083
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.083
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.132 0.083
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.025
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.025
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.025
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.075
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 6.64
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.129 0.025
NUP153 N/A 0.129 0.025
SSB SSB: Lupus La protein 0.129 0.025
KIF11 N/A 0.129 0.025
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.075
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.025
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.025
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.047
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.025
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.047
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.025
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.129 0.025
CDK4 CDK4: Cell division protein kinase 4 0.129 0.047
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.129 0.025
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.129 0.025
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.047
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.129 0.025
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.129 0.025
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.129 0.025
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.025
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.129 0.025
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.025
ZFX ZFX: Zinc finger X-chromosomal protein 0.127 0.028
HIVEP1 N/A 0.127 0.028
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.127 0.083
ZNF335 ZNF335: Zinc finger protein 335 0.127 0.025
SALL1 SALL1, SAL1: Sal-like protein 1 0.125 0.025
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 3.39
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.118 0.075
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.118 0.075
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.118 0.075
CCNH CCNH: Cyclin-H 0.114 0.148
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.114 0.025
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.114 0.148
MTF1 MTF1: Metal regulatory transcription factor 1 0.114 0.025
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.114 0.148
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.075
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.114 0.025
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.114 0.047
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 0.148
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.114 0.075
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.025
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.114 0.148
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.114 0.025
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.075
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.075
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.114 0.075
ETS1 ETS1, EWSR2: Protein C-ets-1 0.114 0.075
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.075
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.075
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.114 0.025
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.148
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.114 0.148
CSK CSK: Tyrosine-protein kinase CSK 0.112 0.098
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.112 0.098
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.111 0.025
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.111 0.044
HSP90AA1 Hsp89-alpha-delta-N 0.111 0.044
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.111 0.098
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.098
TFAP2C TFAP2C: Transcription factor AP-2 gamma 0.102 0.025
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.102 0.025
GTF2F2 N/A 0.0971 0.083
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.025
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.096 0.165
NFATC1 N/A 0.096 0.083
STAT2 STAT2: Signal transducer and activator of transcription 2 0.096 0.165
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.096 0.047
PDK1 PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu 0.094 0.030
TCF7L2 N/A 0.090 0.028
TFAP2B TFAP2B: Transcription factor AP-2 beta 0.090 0.028
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.090 0.025
DNMT1 DNMT1, AIM, DNMT: DNA 0.087 0.028
TGIF2 TGIF2: Homeobox protein TGIF2 0.087 0.028
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.087 0.083
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.165
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.087 0.083
UNG N/A 0.087 0.025
SET SET: Protein SET 0.087 0.028
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.028
TCOF1 N/A 0.087 0.028
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.087 0.052
GNB2L1 Lung cancer oncogene 7 0.087 0.028
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.028
NCOA3 N/A 0.087 0.028
KIF23 N/A 0.087 0.028
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.028
IFI16 N/A 0.087 0.028
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.087 0.025
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.087 0.075
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.087 0.025
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.087 0.075
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.075
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.086 0.025
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.086 0.025
BRPF1 BRPF1, BR140: Peregrin 0.086 0.025
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.025
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.086 0.025
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.086 0.148
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.025
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.086 0.075
CREBBP CREBBP, CBP: CREB-binding protein 0.086 0.025
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.086 0.075
ATM ATM: Serine-protein kinase ATM 0.086 0.148
SOX4 SOX4: Transcription factor SOX-4 0.086 0.025
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.086 0.075
GHR GHR: Growth hormone receptor precursor 0.085 0.034
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.028
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.083
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
UHRF1 0.083 0.052
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.148
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.052
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
PPEF1 N/A 0.083 0.028
MAPK15 N/A 0.083 0.083
C20orf18 N/A 0.083 0.052
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.028
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.0818 0.044
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.0818 0.044
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.036
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.0818 0.044
HIF3A N/A 0.081 0.025
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.081 0.047
H1FX H1FX: Histone H1x 0.080 0.083
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.025
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.025
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.078 0.025
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.078 0.047
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.025
LIG1 LIG1: DNA ligase 1 0.078 0.025
NOL1 N/A 0.078 0.025
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.025
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.078 0.075
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.078 0.025
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.025
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.078 0.025
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.047
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.025
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.075
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.025
CDK7 CDK7, MO15: Cell division protein kinase 7 0.078 0.047
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.025
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.075
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.078 0.025
TIAL1 TIAL1: Nucleolysin TIAR 0.078 0.025
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.078 0.025
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.025
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.025
FNBP1 N/A 0.078 0.025
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.078 0.025
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.025
CDK2 CDK2: Cell division protein kinase 2 0.078 0.047
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.078 0.025
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.078 0.025
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.025
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.025
ERG ERG: Transcriptional regulator ERG 0.077 0.083
MDM4 MDM4, MDMX: Mdm4 protein 0.077 0.083
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.077 0.025
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.077 0.028
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.077 0.028
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.165
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.025
ETS2 ETS2: Protein C-ets-2 0.077 0.083
CCNT2 CCNT2: Cyclin-T2 0.075 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.148
GIT2 N/A 0.075 0.075
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.075 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.075
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.075 0.047
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.075 0.050
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.148
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.075 0.025
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.025
RNF20 0.075 0.047
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.075 0.047
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.075 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.075 0.148
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.047
BRD4 N/A 0.075 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.025
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.025
SOX8 SOX8: Transcription factor SOX-8 0.075 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.075 0.148
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.074 0.109
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.071 3.97
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.071 0.062
API5 N/A 0.070 0.028
UBAP2 N/A 0.070 0.028
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.028
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.028
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.028
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.070 0.028
WDR1 N/A 0.070 0.028
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.070 0.052
STK16 N/A 0.070 0.052
PLEK PLEK, P47: Pleckstrin 0.070 0.165
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.070 0.028
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.028
KIAA0853 N/A 0.070 0.028
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.070 0.028
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.069 0.025
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.069 0.025
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.069 0.148
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.069 0.047
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.069 0.025
ZNF551 N/A 0.069 0.025
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.069 0.025
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.069 0.050
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.075
LIG4 LIG4: DNA ligase 4 0.069 0.075
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.069 0.148
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.069 0.025
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.098
SYK SYK: Tyrosine-protein kinase SYK 0.067 0.098
CTPS CTPS: CTP synthase 1 0.066 0.044
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.066 0.044
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.066 0.098
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.066 2.70
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.066 0.044
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.066 0.044
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.066 0.036
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.025
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.063 0.025
MYH9 MYH9: Myosin-9 0.063 0.025
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.075
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.063 0.025
COPB2 COPB2: Coatomer subunit beta' 0.063 0.025
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.063 0.025
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.025
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.063 0.047
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.025
COPA COPA: Coatomer subunit alpha 0.063 0.025
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.025
WEE1 WEE1: Wee1-like protein kinase 0.063 0.025
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.063 0.047
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.063 0.025
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.063 0.025
PPP1R8 N/A 0.063 0.047
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.025
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.063 0.025
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.025
CORO1C CORO1C, CRNN4: Coronin-1C 0.063 0.025
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.063 0.075
SEC31L1 N/A 0.063 0.025
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.075
RBM7 0.063 0.025
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.025
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.148
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.025
RPS6KB1 N/A 0.063 0.047
PHF10 N/A 0.063 0.025
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.025
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.063 0.148
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.075
WBSCR20A N/A 0.063 0.025
SH3BP3 0.062 0.028
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.052
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.062 0.028
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.083
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.062 0.062
LYN LYN: Tyrosine-protein kinase Lyn 0.061 0.098
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.061 0.109
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.061 0.109
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.060 0.075
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.083
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.044
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.056 0.030
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.056 0.047
SP1 SP1, TSFP1: Transcription factor Sp1 0.056 0.025
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.148
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.056 0.148
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.148
PCAF PCAF: Histone acetyltransferase PCAF 0.056 0.025
ETV1 ETV1, ER81: ETS translocation variant 1 0.056 0.083
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.0554 0.036
STAT4 STAT4: Signal transducer and activator of transcription 4 0.055 0.148
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.055 0.165
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.055 0.028
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.054 0.044
SOS1 SOS1: Son of sevenless homolog 1 0.054 0.148
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.054 0.025
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.083
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.083
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.165
EMD EMD, EDMD, STA: Emerin 0.052 0.028
TRRAP N/A 0.052 0.028
ARFGAP1 N/A 0.052 0.083
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.028
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.028
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.028
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.028
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.028
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.083
CHUK N/A 0.052 0.028
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.028
AFF1 N/A 0.052 0.028
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.028
TOP2B N/A 0.052 0.028
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.028
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.051 0.098
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.051 0.044
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.098
JAK1 0.051 0.098
RNF11 RNF11, CGI-123: RING finger protein 11 0.050 0.047
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.050 0.025
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.049 0.028
STAT3 0.049 0.098
NASP NASP: Nuclear autoantigenic sperm protein 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.049
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.049
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.049 0.109
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.04
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 0.075
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.075
SOX11 SOX11: Transcription factor SOX-11 0.049 0.025
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.049 0.025
ELK1 ELK1: ETS domain-containing protein Elk-1 0.049 0.075
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.049 0.025
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.049 0.148
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.048 0.028
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.048 0.028
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.048 0.052
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.047 1.33
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.047 0.075
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.047 3.97
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.075
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.047 0.025
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.046 0.025
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.046 0.025
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.046 0.025
DIAPH1 Diaphanous 1 0.046 0.025
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.025
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.046 0.075
DOK1 DOK1: Docking protein 1 0.046 0.148
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.025
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.047
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.025
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.046 0.047
KLHDC4 N/A 0.046 0.025
WDR79 N/A 0.046 0.025
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.046 0.025
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.046 0.025
CRSP2 MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol 0.046 0.025
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.046 0.148
CUL4B N/A 0.046 0.025
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.046 0.047
ARMET ARMET, ARP: Protein ARMET precursor 0.046 0.025
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.047
GSK3B N/A 0.046 0.025
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.046 0.047
SYMPK SYMPK, SPK: Symplekin 0.046 0.075
CUL5 CUL5, VACM1: Cullin-5 0.046 0.025
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.025
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.046 0.075
SAPS3 N/A 0.046 0.025
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.025
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.075
MDN1 MDN1, KIAA0301: Midasin 0.046 0.025
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.047
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.148
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.025
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.046 0.025
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.046 0.025
FZR1 N/A 0.046 0.025
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.046 0.025
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.046 0.025
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.046 0.025
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.046 0.049
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.046 0.030
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0453 0.04
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.0446 0.04
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.0446 0.109
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.025
KLC2 KLC2: Kinesin light chain 2 0.044 0.075
EGR1 EGR1, ZNF225: Early growth response protein 1 0.044 0.025
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.044 0.165
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.098
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.043 1.33
VDR VDR, NR1I1: Vitamin D3 receptor 0.043 0.025
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.043 0.075
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.083
SMARCC2 N/A 0.0425 0.028
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.028
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.052
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.165
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.028
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.052
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.0425 0.047
RGS14 N/A 0.0425 0.028
MARK2 N/A 0.0425 0.028
COIL COIL, CLN80: Coilin 0.0425 0.028
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.028
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.028
XRCC4 N/A 0.0425 0.028
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.028
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.0425 0.028
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.028
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.0425 0.083
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.028
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.083
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.041 0.098
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.041 0.044
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.041 0.044
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.04 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 0.109
XPO1 XPO1, CRM1: Exportin-1 0.040 0.044
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.040 0.098
PPARG CREB3L2-PPARgamma 0.039 0.025
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.039 0.028
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.039 0.034
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.025
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.025
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.047
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.075
STK10 STK10: Uncharacterized protein STK10 0.038 0.047
MAFG MAFG: Transcription factor MafG 0.038 0.047
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.038 0.025
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.038 0.025
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.025
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.038 0.025
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.038 0.025
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.038 0.025
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.038 0.047
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.075
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.038 0.047
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.047
POLR2A POLR2A: Uncharacterized protein POLR2A 0.038 0.025
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.038 0.025
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.025
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.038 0.025
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.038 0.025
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.037 0.109
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.037 0.098
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.049
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.036 0.04
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.036 0.109
HD HD, IT15: Huntingtin 0.036 0.049
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.036 0.098
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 0.044
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.036 0.044
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 0.098
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.035 0.075
H1F0 H1F0, H1FV: Histone H1.0 0.035 3.86
SCML2 SCML2: Sex comb on midleg-like protein 2 0.034 0.028
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.034 0.083
FOXL2 FOXL2: Forkhead box protein L2 0.034 0.075
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.034 0.034
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.034 0.034
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.034 0.034
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.034 0.034
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.034 0.062
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.034 0.034
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.034
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.034 0.062
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.034 0.0688
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.034 0.0688
HCK N/A 0.033 0.098
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.033 0.098
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.033 0.098
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.032 0.109
ID2 ID2: DNA-binding protein inhibitor ID-2 0.032 0.028
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.032 0.028
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.052
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.052
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.028
GTF3C1 N/A 0.032 0.028
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.028
VIM VIM: Vimentin 0.032 0.028
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.028
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.032 0.028
AHR AHR: Aryl hydrocarbon receptor precursor 0.032 0.025
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.028
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.165
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.028
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.083
BACH1 BACH1: Transcription regulator protein BACH1 0.032 0.083
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.032 0.044
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.044
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.032 0.036
NRAS NRAS, HRAS1: GTPase NRas precursor 0.032 0.036
PLD1 PLD1: Phospholipase D1 0.032 0.098
CRKL CRKL: Crk-like protein 0.032 0.098
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.044
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.032 0.098
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.032 0.044
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.032 0.036
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.044
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.032 0.044
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.098
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.031 0.025
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.031 0.034
EPOR EPOR: Erythropoietin receptor precursor 0.031 0.034
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.031 0.034
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.031 0.034
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.031 0.028
NFIB N/A 0.031 0.083
RFX1 RFX1: MHC class II regulatory factor RFX1 0.0308 0.075
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.0308 3.97
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.031 0.109
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.030 0.030
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.030 0.062
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.030 0.046
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.044
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.029 0.047
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.025
RUNX1 N/A 0.029 0.025
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.075
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.029 0.025
TOP3A TOP3A, TOP3: DNA topoisomerase 3-alpha 0.029 0.025
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.029 0.025
WDR44 WDR44: WD repeat-containing protein 44 0.029 0.025
JUNB JUNB: Transcription factor jun-B 0.029 0.075
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.047
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.047
POLB POLB: DNA polymerase beta 0.029 0.025
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.047
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.029 0.025
METTL1 METTL1, C12orf1: tRNA 0.029 0.025
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.029 0.075
JUND JUND: Transcription factor jun-D 0.029 0.075
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.029 0.025
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.025
SMCX JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C 0.029 0.025
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.025
CSDA CSDA, DBPA: DNA-binding protein A 0.029 0.025
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.029 0.075
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
C13orf8 N/A 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.028 0.025
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
IRF7 N/A 0.028 0.028
WDR54 N/A 0.028 0.028
DUSP15 N/A 0.028 0.028
RAB4A N/A 0.028 0.052
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.165
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
KIF1B N/A 0.028 0.028
HDAC8 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.028 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.047
CORO6 N/A 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.047
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
NES N/A 0.028 0.025
SNRPB N/A 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.047
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
CABLES1 N/A 0.028 0.028
HDAC7A N/A 0.028 0.025
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
FLJ23436 N/A 0.028 0.025
DSP DSP: Desmoplakin 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
BID BID: BH3-interacting domain death agonist 0.028 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.052
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.165
HES6 HES6: Transcription cofactor HES-6 0.028 0.028
ZNF265 N/A 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.047
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.052
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.025
HIST2H2BE HIST2H2BE, H2BFQ: Histone H2B type 2-E 0.028 0.025
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.028 0.025
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.027 0.098
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.027 0.098
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.027 0.098
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.027 0.049
CIITA CIITA, MHC2TA: MHC class II transactivator 0.027 0.049
BMX N/A 0.0263 0.109
TH TH, TYH: Tyrosine 3-monooxygenase 0.026 0.046
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.026 0.025
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.026 0.075
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.025
MECP2 MECP2: Methyl-CpG-binding protein 2 0.026 0.028
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.028
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.028
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.028
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.026 0.047
KRT18 KRT18: Uncharacterized protein KRT18 0.026 0.028
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.052
PRKAA1 N/A 0.026 0.052
MEF2A N/A 0.026 0.028
NUP214 N/A 0.026 0.028
GRLF1 N/A 0.026 0.083
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.028
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.026 0.052
RECQL RECQL, RECQL1: ATP-dependent DNA helicase Q1 0.0255 0.354
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.025 0.034
IL9R IL9R: Interleukin-9 receptor precursor 0.025 0.034
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.025 0.034
ITGB4 N/A 0.025 0.034
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.075
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.047
PRKCB1 N/A 0.025 0.025
CREB1 CREB1: cAMP response element-binding protein 0.025 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.075
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
ATXN2L N/A 0.025 0.025
ELMO1 N/A 0.025 0.148
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
GRK6 N/A 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
NUP98 N/A 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
SEC13L1 N/A 0.025 0.025
NIPBL N/A 0.025 0.075
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.047
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
C20orf77 N/A 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.075
ADK ADK: Adenosine kinase 0.025 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 1.33
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.047
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.075
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
HTATIP N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
DIDO1 N/A 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.047
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.047
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
TCEA1 N/A 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.148
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.047
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.075
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
SON 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.047
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.047
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.148
BCOR N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
KCTD1 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
MAX MAX: Protein max 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.047
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.075
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
0.299
Total Score 2.99