PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between TP53 and LAMR1

The interaction score between TP53 and LAMR1 is 3.64.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between TP53 and LAMR1 = 0.66

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

7.78E-3

Orthology

Organism	TP53 Orthologue		LAMR1 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
human	IPI00215713	0.16	IPI00411639	0.95
human	IPI00215713	0.16	IPI00413108	0.675
human	IPI00215713	0.16	IPI00477975	0.625
human	IPI00215713	0.16	IPI00398958	0.924
human	IPI00215713	0.16	IPI00399077	0.697
human	IPI00215713	0.16	IPI00399036	0.842
human	IPI00215713	0.16	IPI00739930	0.874
fly	Q8IH92	0.16	Q7KW10	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

No domains were used in calculating likelihood of interaction

0.014

Post-translational Modifications

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Protein: LAMR1

PTM	Residue	Reference
N-acetylserine	1	HPRD
Phosphotyrosine	138	HPRD

Localisation

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: LAMR1

Localisation	Reference
Plasma membrane	HPRD
Nucleolus	HPRD
Secreted	HPRD
Cytoplasm	HPRD
Ribosome	HPRD

Transitive Score

The common interactors between TP53 and LAMR1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andLAMR1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and LAMR1 has 856 interactors of which there are 527 common interactors.

Common Interactor	Name of Common Interactor	Score for TP53-Interactor (?)	Score for LAMR1-Interactor (?)
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	4.77	0.025
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	2.54	0.040
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	2.08	0.032
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.964	0.154
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.822	0.066
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.704	0.704
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.704	0.141
PCNA	PCNA: Proliferating cell nuclear antigen	0.704	0.032
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.651	0.036
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.541	0.052
MCM3	MCM3: DNA replication licensing factor MCM3	0.515	0.040
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.503	0.078
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.471	0.032
NBN	NBN, NBS, NBS1, P95: Nibrin	0.430	0.0446
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.430	0.074
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.430	0.087
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.430	0.074
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.430	0.036
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.430	0.032
DDX21	DDX21: Nucleolar RNA helicase 2	0.430	0.074
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.425	8.55
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.385	0.040
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.385	0.066
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.385	0.040
CCNB1	Cyclin B1	0.385	0.032
SRF	SRF: Serum response factor	0.344	0.032
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	0.726
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.304	0.276
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.290	0.040
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.276	0.066
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.276	0.066
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.066
POLA2	POLA2: DNA polymerase subunit alpha B	0.276	0.040
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.276	0.066
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.276	0.032
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.040
CENPA	CENPA: Histone H3-like centromeric protein A	0.269	0.027
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.260	0.074
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.260	0.032
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.260	0.0446
EP300	N/A	0.254	0.032
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.253	0.087
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.241	0.066
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.241	0.032
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.241	0.032
POLR2H	POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3	0.241	0.033
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.233	0.066
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.233	0.066
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.276
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.233	0.078
YY1	YY1: Transcriptional repressor protein YY1	0.233	0.066
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.233	0.040
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.216	0.038
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.210	0.040
RB1	RB1: Retinoblastoma-associated protein	0.210	0.0446
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.210	0.0446
ELF1	ELF1: ETS-related transcription factor Elf-1	0.210	0.074
MATR3	MATR3, KIAA0723: Matrin-3	0.210	0.0446
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.208	0.032
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.188	0.040
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.066
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	0.129
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.188	0.032
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.188	0.066
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.032
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.188	0.066
CXorf9	N/A	0.188	0.063
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.040
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.162	0.070
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.155	0.0446
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.036
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.0333
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.040
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.146	0.129
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.146	0.040
PPP2CA	PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	0.145	0.038
ABCF1	N/A	0.144	0.087
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.087
MKI67	MKI67: Antigen KI-67	0.144	0.027
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.144	0.087
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.144	0.472
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.157
ESPL1	N/A	0.144	0.052
PTMA	N/A	0.144	0.157
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.141	0.046
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.141	0.276
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.141	0.078
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.141	0.129
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.140	0.032
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.139	0.038
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.139	0.032
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.139	10.50
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.139	0.032
RELA	RELA, NFKB3: Transcription factor p65	0.139	0.032
KIAA1012	KIAA1012: Protein TRS85 homolog	0.139	0.078
CDC23	CDC23: Cell division cycle protein 23 homolog	0.137	0.078
APRT	APRT: Adenine phosphoribosyltransferase	0.137	0.048
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.137	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.030
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.030
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.132	0.027
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.132	0.0425
IRF3	IRF3: Interferon regulatory factor 3	0.132	0.0446
CDK4	CDK4: Cell division protein kinase 4	0.129	0.078
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.129	0.040
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.129	0.129
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.141
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.066
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.129	0.032
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.066
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.066
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.129	0.040
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.040
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.040
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.129	0.129
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.129	0.066
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.066
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.066
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.141
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.066
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.066
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.066
NUP153	N/A	0.129	0.066
SSB	SSB: Lupus La protein	0.129	0.141
KIF11	N/A	0.129	0.032
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.129	17.50
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.063
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.027
HIVEP1	N/A	0.127	0.036
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.124	0.046
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.066
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.118	0.129
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.118	0.032
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.063
FKBP4	FKBP4: FK506-binding protein 4	0.114	0.038
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.114	0.046
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.114	0.046
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.046
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.114	0.038
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.114	0.032
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.114	0.032
AIP	AIP, XAP2: AH receptor-interacting protein	0.114	0.063
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.114	0.063
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.114	0.029
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.112	0.078
CSK	CSK: Tyrosine-protein kinase CSK	0.112	0.129
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.112	0.078
HSP90AA1	Hsp89-alpha-delta-N	0.111	0.063
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.111	0.078
STAT6	STAT6: Signal transducer and activator of transcription 6	0.111	0.078
GTF2F2	N/A	0.0971	0.027
NFATC1	N/A	0.096	0.036
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.093	0.827
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.087	0.052
GNB2L1	Lung cancer oncogene 7	0.087	0.472
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.074
NCOA3	N/A	0.087	0.074
SET	SET: Protein SET	0.087	0.157
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.0446
TCOF1	N/A	0.087	0.0446
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.0446
IFI16	N/A	0.087	0.0446
KIF23	N/A	0.087	0.027
DNMT1	DNMT1, AIM, DNMT: DNA	0.087	0.0446
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.087	0.027
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.087	0.074
UNG	N/A	0.087	0.032
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.087	0.027
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.087	0.032
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.087	0.063
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.087	0.046
BRPF1	BRPF1, BR140: Peregrin	0.086	0.038
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.086	0.038
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.086	0.029
ATM	ATM: Serine-protein kinase ATM	0.086	0.046
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.084	0.052
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.028
MAPK15	N/A	0.083	0.028
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.025
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.028
NAPG	NAPG, SNAPG: Gamma-soluble NSF attachment protein	0.0818	0.038
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.0818	0.063
RPL29	RPL29: 60S ribosomal protein L29	0.081	0.144
H1FX	H1FX: Histone H1x	0.080	0.036
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.032
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.078	0.040
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.066
FNBP1	N/A	0.078	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.040
CDK2	CDK2: Cell division protein kinase 2	0.078	0.063
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.078	0.040
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.141
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.066
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.066
LIG1	LIG1: DNA ligase 1	0.078	0.066
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.078	0.141
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.078	0.066
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.078	0.032
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.078	0.141
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.066
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.141
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.066
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.038
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.129
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.066
CDK7	CDK7, MO15: Cell division protein kinase 7	0.078	0.063
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.129
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.078	0.066
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.066
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.276
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.032
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.066
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.066
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.026
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.077	0.0425
EEF2	EEF2, EF2: Elongation factor 2	0.075	0.276
GIT2	N/A	0.075	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	0.025
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.074	0.026
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.074	0.078
PHB2	PHB2, BAP, REA: Prohibitin-2	0.074	0.144
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.087
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.071	0.032
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.070	0.036
WDR1	N/A	0.070	0.036
PLEK	PLEK, P47: Pleckstrin	0.070	0.036
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.070	0.027
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.070	0.087
STK16	N/A	0.070	0.0425
KIAA0853	N/A	0.070	0.0446
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.0446
API5	N/A	0.070	0.087
UBAP2	N/A	0.070	0.070
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.0446
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.036
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.070
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.029
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.069	0.029
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.067	0.046
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.067	0.046
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.067	0.038
SUMO2	SUMO2, SMT3B, SMT3H2: Small ubiquitin-related modifier 2 precursor	0.0668	0.442
SYK	SYK: Tyrosine-protein kinase SYK	0.067	0.063
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.066	0.129
HSPD1		0.066	20.60
CSE1L	CSE1L, CAS, XPO2: Exportin-2	0.066	3.61
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.078
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.066	0.078
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.078
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	23.90
QARS	QARS: Glutaminyl-tRNA synthetase	0.066	0.276
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.066	0.129
CTPS	CTPS: CTP synthase 1	0.066	0.078
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.129
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	34.20
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.066	0.078
HNRPK	N/A	0.066	0.129
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.066	0.129
GPI	GPI: Glucose-6-phosphate isomerase	0.066	0.046
KPNB1	KPNB1, NTF97: Importin subunit beta-1	0.066	1.20
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.032
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.078
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.063	0.040
PPP1R8	N/A	0.063	0.066
MTA1	MTA1: Metastasis-associated protein MTA1	0.063	0.032
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.078
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.040
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.063
RPS6KB1	N/A	0.063	0.078
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.129
WBSCR20A	N/A	0.063	0.066
PHF10	N/A	0.063	0.066
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.063	0.078
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.063	0.078
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.141
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.066
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.066
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.040
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.046
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.040
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.063	0.038
COPA	COPA: Coatomer subunit alpha	0.063	0.063
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.040
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.063	0.032
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.032
WEE1	WEE1: Wee1-like protein kinase	0.063	0.046
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.129
LYN	LYN: Tyrosine-protein kinase Lyn	0.061	0.046
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.061	0.0425
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.061	0.0425
EIF3S10	EIF3S10, KIAA0139: Eukaryotic translation initiation factor 3 subunit 10	0.059	1.82
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.057	0.032
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.0554	0.078
SUPT5H	SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5	0.054	0.054
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.052	0.036
CHUK	N/A	0.052	0.052
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.036
TOP2B	N/A	0.052	0.0446
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.074
EMD	EMD, EDMD, STA: Emerin	0.052	0.027
TRRAP	N/A	0.052	0.070
ARFGAP1	N/A	0.052	0.036
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.052
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.036
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.0446
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.070
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.087
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.087
JAK1		0.051	0.046
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.051	0.029
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.051	0.038
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.051	0.029
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.028
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.049	0.028
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.049	0.028
STAT3		0.049	0.025
S100A16	S100A16, AAG13: Protein S100-A16	0.049	0.028
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.028
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.025
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.063
SAPS3	N/A	0.046	0.078
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.046
SYMPK	SYMPK, SPK: Symplekin	0.046	0.038
CUL5	CUL5, VACM1: Cullin-5	0.046	0.032
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.066
MDN1	MDN1, KIAA0301: Midasin	0.046	0.078
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.078
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.046	0.038
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.046	0.063
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.046	0.032
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.032
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.046	0.063
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.078
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.032
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.046	0.040
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.032
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	1.26
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.046	0.040
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.046	0.029
DOK1	DOK1: Docking protein 1	0.046	0.046
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.063
KLHDC4	N/A	0.046	0.078
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.046	0.032
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.046	0.032
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	0.063
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.046
CUL4B	N/A	0.046	0.032
GSK3B	N/A	0.046	0.046
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.046	0.063
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.046	0.0425
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.0453	0.032
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.0453	0.026
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.0446	0.070
GTPBP4	GTPBP4, CRFG, NOG1: Nucleolar GTP-binding protein 1	0.0446	0.054
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.0446	0.052
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.087
TK1	TK1: Thymidine kinase, cytosolic	0.0446	0.063
FUBP1	N/A	0.0446	0.307
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.044	0.025
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.044	0.025
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.036
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.052
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0425	0.027
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.0425	0.026
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.0425	0.070
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.0425
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.052
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.0425	0.0425
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.0425	0.032
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.052
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.0425	1.03
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.0446
MARK2	N/A	0.0425	0.0425
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.041	0.038
EXOC2	N/A	0.041	0.038
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.041	0.029
STUB1	STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1	0.041	0.038
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	0.028
LCP1	LCP1, PLS2: Plastin-2	0.040	0.063
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.040	0.129
CD2AP	CD2AP: CD2-associated protein	0.040	0.078
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.040	1.20
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.040	0.063
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.040	0.078
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.040	0.078
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.129
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.129
THOP1	THOP1: Thimet oligopeptidase	0.040	0.046
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.276
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.040	0.078
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.827
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.827
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.040	0.078
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.046
HRB2	KRR1, HRB2: KRR1 small subunit processome component homolog	0.040	5.97
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.040	0.063
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.827
LPXN	LPXN, LDLP: Leupaxin	0.040	0.078
XPO1	XPO1, CRM1: Exportin-1	0.040	0.129
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.039	0.026
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.038	0.063
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.038
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.038	0.046
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.038	0.032
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.038	0.040
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.038	0.038
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.038	0.063
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.046
STK10	STK10: Uncharacterized protein STK10	0.038	0.046
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.032
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.038	0.038
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.037	0.026
SRPR	SRPR: Uncharacterized protein SRPR	0.036	0.070
HD	HD, IT15: Huntingtin	0.036	0.070
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.036	0.070
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.052
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.036	0.0425
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.036	0.025
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.036	0.025
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.025
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.036	0.025
TRPV1	TRPV1: Vanilloid receptor variant TRPV1b	0.034	0.109
TRPV4	TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb	0.034	0.109
AXIN1		0.0333	0.028
YWHAG	YWHAG: 14-3-3 protein gamma	0.0333	0.028
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.033	0.038
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.032	0.0425
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.0425
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.032	0.052
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.0425
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.027
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.032	0.0425
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.032	0.0425
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.032	0.078
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.032	0.038
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.078
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.827
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.032	0.144
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.032	0.063
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.032	0.827
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.032	0.063
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.063
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	0.276
ACTG1	ACTB: Actin, cytoplasmic 1	0.032	0.078
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.032	0.063
FLII	FLII, FLIL: Protein flightless-1 homolog	0.032	0.063
PPARBP	N/A	0.032	0.129
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.046
CRKL	CRKL: Crk-like protein	0.032	0.078
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.078
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.078
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.032	0.078
PRDX1	PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1	0.032	0.046
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.078
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	0.031	0.026
TRPV6	TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6	0.030	0.098
JUND	JUND: Transcription factor jun-D	0.029	0.032
CSDA	CSDA, DBPA: DNA-binding protein A	0.029	0.029
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.038
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.029	0.046
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.029	0.038
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.029	0.032
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.029	0.038
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.029	0.029
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.028	0.025
NF2	NF2, SCH: Merlin	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.028	0.025
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
PHLDB2	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
MAPKAPK5	N/A	0.028	0.028
CDC2	CDC2: Cell division control protein 2 homolog	0.028	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.028	0.025
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.027	0.029
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.027	0.052
MPG	N/A	0.027	0.070
YWHAQ	YWHAQ: 14-3-3 protein theta	0.027	0.087
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.027	0.087
FABP5	FABP5: Fatty acid-binding protein, epidermal	0.027	0.038
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.026	0.026
PRKAA1	N/A	0.026	0.032
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.026	0.026
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.032
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.026	0.038
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.025
BCOR	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.160
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
PRKCB1	N/A	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
ELMO1	N/A	0.025	0.025
GRK6	N/A	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CAMK2A	N/A	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
C11orf58	SMAP, C11orf58: Small acidic protein	0.025	0.025
PTGES3	PTGES3, P23, TEBP: Prostaglandin E synthase 3	0.025	0.025

0.228

Total Score

3.64