PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between TP53 and RPA2

The interaction score between TP53 and RPA2 is 10.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between TP53 and RPA2 = 0.49

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

4.62E-3

Orthology

Organism	TP53 Orthologue		RPA2 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
fly	Q8IH92	0.16	Q8SXG3	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in TP53 and RPA2:

Domains in TP53

Domains in RPA2

IPR008967	p53-like transcription factor, DNA-binding
IPR002117	p53 tumor antigen
IPR010991	p53, tetramerisation
IPR011615	P53_DNA_bd.
IPR012346	P53_RUNT_DNA_bd.

IPR004365	OB-fold nucleic acid binding
IPR011991	Wing_hlx_DNA_bd.
IPR012340	OB_NA_bd_sub.

The Chi square scores for co-occurrence of domains that are present in TP53 and RPA2 are listed below.

Domain 1		Domain 2		Chi Square
IPR008967	p53-like transcription factor, DNA-binding	IPR011991	Wing_hlx_DNA_bd.	0.00778109

The background colour of the table refers to:

Blue Domain is only present in TP53
Yellow Domain is only present in RPA2
Green Domain is present in both TP53 and RPA2

0.052

Post-translational Modifications

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Protein: RPA2

PTM	Residue	Reference
N-acetylmethionine	1	HPRD
Phosphorylation	4	PubMed, HPRD
Phosphorylation	8	PubMed, HPRD
Phosphorylation	11	PubMed, HPRD
Phosphorylation	12	PubMed, HPRD
Phosphorylation	13	PubMed, HPRD
Phosphorylation	21	PubMed, HPRD
Phosphorylation	23	PubMed, HPRD
Phosphorylation	29	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphoserine	29	PubMed, HPRD
Phosphoserine	33	PubMed, HPRD
Phosphothreonine	21	PubMed, HPRD

Localisation

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: RPA2

Localisation	Reference
Nucleus	HPRD

Transitive Score

The common interactors between TP53 and RPA2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andRPA2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and RPA2 has 1321 interactors of which there are 900 common interactors.

Common Interactor	Name of Common Interactor	Score for TP53-Interactor (?)	Score for RPA2-Interactor (?)
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	4.77	0.251
H2AFX	H2AFX, H2AX: Histone H2A.x	4.27	0.038
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	2.54	0.063
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	2.08	0.139
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	1.58	0.038
SMAD4	SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4	1.58	0.114
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	1.26	0.056
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.964	0.583
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.822	0.188
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.704	0.763
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.704	0.078
PCNA	PCNA: Proliferating cell nuclear antigen	0.704	0.038
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.651	0.052
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.541	0.052
SP100	N/A	0.525	0.210
MCM3	MCM3: DNA replication licensing factor MCM3	0.515	0.372
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.503	0.063
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.503	0.063
SREBF2	N/A	0.475	0.052
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.471	0.275
NBN	NBN, NBS, NBS1, P95: Nibrin	0.430	0.260
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.430	0.515
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.430	0.210
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.430	0.260
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.430	0.155
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.430	0.087
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.430	0.0425
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.430	0.139
DDX21	DDX21: Nucleolar RNA helicase 2	0.430	0.416
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.425	0.063
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.385	0.139
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.385	0.461
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.385	0.188
CCNB1	Cyclin B1	0.385	0.225
SP3	SP3: Transcription factor Sp3	0.347	0.188
SRF	SRF: Serum response factor	0.344	0.139
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.318	0.114
SNRPA	SNRPA: U1 small nuclear ribonucleoprotein A	0.307	0.037
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	0.046
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.304	0.063
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.290	0.063
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.284	0.114
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.276	0.233
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.276	0.188
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.063
POLA2	POLA2: DNA polymerase subunit alpha B	0.276	0.046
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.276	0.233
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.276	0.046
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.063
CENPA	CENPA: Histone H3-like centromeric protein A	0.269	0.0425
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.260	0.307
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.260	0.416
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.260	0.114
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.260	0.210
EP300	N/A	0.254	0.046
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.254	0.029
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.253	0.052
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.245	0.046
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.241	0.275
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.241	0.225
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.241	0.225
POLR2H	POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3	0.241	0.126
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.233	0.233
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.233	0.188
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.078
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.233	0.063
YY1	YY1: Transcriptional repressor protein YY1	0.233	0.233
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.233	0.233
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.227	0.078
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.216	0.139
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.210	0.461
RB1	RB1: Retinoblastoma-associated protein	0.210	0.307
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.210	0.416
ELF1	ELF1: ETS-related transcription factor Elf-1	0.210	0.260
MATR3	MATR3, KIAA0723: Matrin-3	0.210	0.210
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.208	0.054
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.188	0.275
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.188
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	61.60
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.188	0.038
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.188	0.372
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.114
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.188	0.233
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.372
CXorf9	N/A	0.188	0.078
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.372
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.188	0.188
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.187	0.075
MYB	MYB: Myb proto-oncogene protein	0.176	0.077
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.172	0.136
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.172	0.136
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.162	0.0425
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.156	0.109
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.155	0.210
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.155	0.132
ZNF267	ZNF267: Zinc finger protein 267	0.155	0.210
ERF	ERF: ETS domain-containing transcription factor ERF	0.155	0.096
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.127
MITF	MITF: Microphthalmia-associated transcription factor	0.152	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.152	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.152	0.052
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.028
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.188
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.146	0.275
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.146	0.233
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.146	0.372
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.146	0.086
PPP2CA	PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	0.145	0.038
ABCF1	N/A	0.144	0.144
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.070
MKI67	MKI67: Antigen KI-67	0.144	0.127
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.144	0.070
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.144	0.070
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.260
ESPL1	N/A	0.144	0.0425
PTMA	N/A	0.144	0.087
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.141	0.038
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.141	122.00
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.141	0.063
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.141	0.188
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.141	0.063
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.140	0.077
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.140	0.049
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.139	0.114
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.139	0.069
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.139	0.372
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.139	4.27
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.139	0.372
COPE	COPE: Coatomer subunit epsilon	0.139	0.046
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.139	0.461
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.139	0.171
RELA	RELA, NFKB3: Transcription factor p65	0.139	0.188
KIAA1012	KIAA1012: Protein TRS85 homolog	0.139	0.063
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.139	0.275
CDC23	CDC23: Cell division cycle protein 23 homolog	0.137	0.046
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.137	0.078
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.137	0.047
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.137	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.137	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.075
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.075
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.132	0.096
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.132	0.152
IRF3	IRF3: Interferon regulatory factor 3	0.132	0.210
CDK4	CDK4: Cell division protein kinase 4	0.129	0.046
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.129	0.063
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.129	0.063
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.188
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.188
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.129	0.038
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.188
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.063
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.129	16.60
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.063
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.046
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.129	0.063
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.129	0.046
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.275
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.078
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.063
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.063
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.046
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.188
NUP153	N/A	0.129	0.078
SSB	SSB: Lupus La protein	0.129	0.188
KIF11	N/A	0.129	0.038
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.129	0.188
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.038
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.078
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.038
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.038
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.155
ZNF335	ZNF335: Zinc finger protein 335	0.127	0.114
ZFX	ZFX: Zinc finger X-chromosomal protein	0.127	0.096
HIVEP1	N/A	0.127	0.155
SALL1	SALL1, SAL1: Sal-like protein 1	0.125	0.049
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.124	0.171
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.275
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.118	0.233
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.118	0.086
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.114	0.114
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.046
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.114	0.038
ETS1	ETS1, EWSR2: Protein C-ets-1	0.114	0.139
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.114	0.046
FKBP4	FKBP4: FK506-binding protein 4	0.114	0.038
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.114	0.078
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.114	0.063
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.038
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.114	0.114
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.114	0.087
CCNH	CCNH: Cyclin-H	0.114	0.225
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.114	0.188
MTF1	MTF1: Metal regulatory transcription factor 1	0.114	0.114
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.114	0.063
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.114	0.225
AIP	AIP, XAP2: AH receptor-interacting protein	0.114	0.063
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.114	0.063
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.114	0.139
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.114	0.069
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.114	0.139
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.112	0.372
CSK	CSK: Tyrosine-protein kinase CSK	0.112	0.129
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.112	0.046
ZBTB16	ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16	0.111	0.049
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.111	0.188
HSP90AA1	Hsp89-alpha-delta-N	0.111	0.046
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.111	0.063
STAT6	STAT6: Signal transducer and activator of transcription 6	0.111	0.188
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.102	0.038
GTF2F2	N/A	0.0971	0.096
STAT2	STAT2: Signal transducer and activator of transcription 2	0.096	0.077
NFATC1	N/A	0.096	0.307
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.096	0.114
EEA1	EEA1, ZFYVE2: Early endosome antigen 1	0.096	0.049
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.096	0.052
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.093	0.063
SATB2	SATB2, KIAA1034: DNA-binding protein SATB2	0.090	0.049
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.087	0.0425
GNB2L1	Lung cancer oncogene 7	0.087	0.070
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.210
NCOA3	N/A	0.087	0.070
SET	SET: Protein SET	0.087	0.070
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.260
TCOF1	N/A	0.087	0.070
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.430
IFI16	N/A	0.087	0.087
KIF23	N/A	0.087	0.032
DNMT1	DNMT1, AIM, DNMT: DNA	0.087	0.070
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.087	0.416
TGIF2	TGIF2: Homeobox protein TGIF2	0.087	0.210
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.087	0.070
UNG	N/A	0.087	0.063
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.087	0.0425
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.087	0.063
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.087	0.275
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.087	0.086
SOX4	SOX4: Transcription factor SOX-4	0.086	0.069
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.086	0.372
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.086	0.225
BRPF1	BRPF1, BR140: Peregrin	0.086	0.275
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.086	0.118
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.086	0.171
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.086	0.114
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.086	0.275
CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1	0.086	0.097
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.086	0.372
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.086	0.139
CREBBP	CREBBP, CBP: CREB-binding protein	0.086	0.372
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.086	0.029
ATM	ATM: Serine-protein kinase ATM	0.086	0.114
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.084	0.070
PPEF1	N/A	0.083	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.083	0.083
MAPK15	N/A	0.083	0.052
C20orf18	N/A	0.083	0.052
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.083
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.083	0.083
UHRF1		0.083	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.083	0.083
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.025
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.083	0.083
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.165
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.083	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.083	0.083
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.083	0.083
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.083	0.083
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.165
NAPG	NAPG, SNAPG: Gamma-soluble NSF attachment protein	0.0818	0.038
KIAA0664	KIAA0664: Putative eukaryotic translation initiation factor 3 subunit	0.0818	0.038
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.0818	0.038
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.0818	0.233
H1FX	H1FX: Histone H1x	0.080	0.127
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.233
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.078	0.146
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.233
FNBP1	N/A	0.078	0.078
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.188
CDK2	CDK2: Cell division protein kinase 2	0.078	0.038
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.078	0.063
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.188
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.078
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.233
LIG1	LIG1: DNA ligase 1	0.078	0.046
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.078	0.188
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.078	0.046
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.078	0.063
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.078	0.029
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.078	0.078
NOL1	N/A	0.078	0.063
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.078
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.078
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.078
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.029
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.063
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.233
CDK7	CDK7, MO15: Cell division protein kinase 7	0.078	0.046
MYBL2	MYBL2, BMYB: Myb-related protein B	0.078	0.086
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.046
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.078	0.118
U2AF1	U2AF1, U2AF35, U2AFBP: Splicing factor U2AF 35 kDa subunit	0.078	0.037
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.063
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.078
RBM28	RBM28: RNA-binding protein 28	0.078	0.027
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.046
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.188
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.233
ETS2	ETS2: Protein C-ets-2	0.077	0.062
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.096
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.077	0.056
ERG	ERG: Transcriptional regulator ERG	0.077	0.062
MDM4	MDM4, MDMX: Mdm4 protein	0.077	0.034
SNAI1	SNAI1, SNAH: Zinc finger protein SNAI1	0.077	0.056
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.077	0.077
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.077	0.0425
EEF2	EEF2, EF2: Elongation factor 2	0.075	0.372
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.075	0.075
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.075	0.025
BRD4	N/A	0.075	0.148
SOX8	SOX8: Transcription factor SOX-8	0.075	0.075
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.075	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.075	0.075
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.075	0.075
GIT2	N/A	0.075	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.075	0.075
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.075	0.148
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.075	0.025
CCNT2	CCNT2: Cyclin-T2	0.075	0.148
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.075	0.075
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.148
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.075	0.075
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.075	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.075	0.148
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.075	0.075
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.075	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.148
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.148
RNF20		0.075	0.075
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.074	0.026
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.074	0.063
PHB2	PHB2, BAP, REA: Prohibitin-2	0.074	0.070
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.052
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.071	0.188
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.070	0.070
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.070	0.052
WDR1	N/A	0.070	0.070
PLEK	PLEK, P47: Pleckstrin	0.070	0.070
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.070	0.032
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.070	0.052
STK16	N/A	0.070	0.0425
KIAA0853	N/A	0.070	0.052
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.210
API5	N/A	0.070	0.052
UBAP2	N/A	0.070	0.070
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.052
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.087
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.087
ZNF551	N/A	0.069	0.069
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.069	0.086
LIG4	LIG4: DNA ligase 4	0.069	0.069
GCN5L2	GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2	0.069	0.225
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.029
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.069	0.114
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.069	0.046
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.069	0.086
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.069	0.056
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.069	0.111
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.067	0.046
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.067	0.114
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.067	0.038
SYK	SYK: Tyrosine-protein kinase SYK	0.067	0.046
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.066	0.078
HSPD1		0.066	0.038
CSE1L	CSE1L, CAS, XPO2: Exportin-2	0.066	0.027
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.063
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.066	0.063
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.046
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.063
QARS	QARS: Glutaminyl-tRNA synthetase	0.066	0.078
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.066	0.046
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.066	0.038
CTPS	CTPS: CTP synthase 1	0.066	0.046
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.063
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.046
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.066	0.063
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.046
HNRPK	N/A	0.066	0.078
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.066	0.063
GPI	GPI: Glucose-6-phosphate isomerase	0.066	0.038
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.063
KPNB1	KPNB1, NTF97: Importin subunit beta-1	0.066	0.045
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.066	0.038
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.038
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.046
CORO1C	CORO1C, CRNN4: Coronin-1C	0.063	0.029
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.063	0.046
PPP1R8	N/A	0.063	0.188
MTA1	MTA1: Metastasis-associated protein MTA1	0.063	0.139
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.063
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.372
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.046
RPS6KB1	N/A	0.063	0.063
SEC31L1	N/A	0.063	0.038
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.188
RBM7		0.063	0.139
WBSCR20A	N/A	0.063	0.078
PHF10	N/A	0.063	0.046
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.063	0.046
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.063	0.078
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.063
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.046
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.233
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.063
MYH9	MYH9: Myosin-9	0.063	0.038
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.054
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.063	0.046
COPB2	COPB2: Coatomer subunit beta'	0.063	0.038
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.046
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.063	0.038
COPA	COPA: Coatomer subunit alpha	0.063	0.038
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.078
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.063	0.038
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.063
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.188
WEE1	WEE1: Wee1-like protein kinase	0.063	0.046
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.063
CRLF3	N/A	0.063	0.036
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.062	0.127
SH3BP3		0.062	0.077
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.062	0.191
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.062	0.077
LYN	LYN: Tyrosine-protein kinase Lyn	0.061	0.046
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.061	0.052
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.061	0.032
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.060	0.086
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.127
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.057	0.026
MYCBP2	MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2	0.056	0.032
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.056	0.035
PCAF	PCAF: Histone acetyltransferase PCAF	0.056	0.136
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.056	0.097
SP1	SP1, TSFP1: Transcription factor Sp1	0.056	0.056
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.056	0.043
ETV1	ETV1, ER81: ETS translocation variant 1	0.056	0.049
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.0554	0.078
STAT4	STAT4: Signal transducer and activator of transcription 4	0.055	0.114
TAF1	TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1	0.055	0.123
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.054	0.063
SOS1	SOS1: Son of sevenless homolog 1	0.054	0.046
RPA1	RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit	0.053	80.90
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.083
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.083
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.052	0.210
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.077
CHUK	N/A	0.052	0.052
AFF1	N/A	0.052	0.0425
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.210
TOP2B	N/A	0.052	0.070
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.052
EMD	EMD, EDMD, STA: Emerin	0.052	0.0425
TRRAP	N/A	0.052	0.052
ARFGAP1	N/A	0.052	0.052
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.052
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.087
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.070
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.210
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.052
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.052
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.070
JAK1		0.051	0.063
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.051	0.114
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.051	0.029
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.051	0.071
SMARCA1	SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1	0.050	0.044
ZHX3	ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3	0.049	0.055
SF3A3	SF3A3, SAP61: Splicing factor 3A subunit 3	0.049	0.036
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.083
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.049	0.028
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.049	0.028
STAT3		0.049	0.075
NASP	NASP: Nuclear autoantigenic sperm protein	0.049	0.028
S100A16	S100A16, AAG13: Protein S100-A16	0.049	0.028
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.083
BNC1	BNC1, BNC: Zinc finger protein basonuclin-1	0.049	0.044
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.049	0.069
ELK1	ELK1: ETS domain-containing protein Elk-1	0.049	0.056
SOX11	SOX11: Transcription factor SOX-11	0.049	0.049
KLF5	KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5	0.049	0.050
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.048	0.026
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.075
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.047	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.047	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.047	0.075
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.047	0.075
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.148
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.188
SAPS3	N/A	0.046	0.038
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.046
SYMPK	SYMPK, SPK: Symplekin	0.046	0.114
CUL5	CUL5, VACM1: Cullin-5	0.046	0.046
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.139
MDN1	MDN1, KIAA0301: Midasin	0.046	0.063
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.046
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.046	0.038
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.046	0.046
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.046	0.029
FZR1	N/A	0.046	0.038
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.046	0.046
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.046	0.063
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.038
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.046	0.063
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.046
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.188
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.046
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.114
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.046	0.078
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.046	0.038
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.118
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	0.029
DIAPH1	Diaphanous 1	0.046	0.078
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.046	0.078
DOK1	DOK1: Docking protein 1	0.046	0.038
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.063
KLHDC4	N/A	0.046	0.078
WDR79	N/A	0.046	0.038
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.046	0.046
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.046	0.063
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	0.063
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.046	0.029
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.046
CUL4B	N/A	0.046	0.046
GSK3B	N/A	0.046	0.046
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.046
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.046	0.063
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.046	0.096
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.0453	0.026
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.0446	0.052
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.0446	0.032
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.0425
TK1	TK1: Thymidine kinase, cytosolic	0.0446	0.038
FUBP1	N/A	0.0446	0.416
EGR1	EGR1, ZNF225: Early growth response protein 1	0.044	0.044
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.044	0.025
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.044	0.025
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.043	0.038
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.043	0.056
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.0425	0.127
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.0425	0.026
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.052
XRCC4	N/A	0.0425	0.032
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.052
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0425	0.210
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.0425	0.052
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.070
SMARCC2	N/A	0.0425	0.052
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.0425
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.0425	0.052
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.0425	0.0425
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.052
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.155
RGS14	N/A	0.0425	0.0425
MARK2	N/A	0.0425	0.032
COIL	COIL, CLN80: Coilin	0.0425	0.052
DHX15	DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase	0.042	0.067
HELLS	HELLS, PASG, Nbla10143, SMARCA6: Lymphoid-specific helicase	0.042	0.036
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.041	0.038
EXOC2	N/A	0.041	0.114
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.041	0.038
STUB1	STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1	0.041	0.029
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	0.028
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	0.028
LCP1	LCP1, PLS2: Plastin-2	0.040	0.078
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.040	0.078
CD2AP	CD2AP: CD2-associated protein	0.040	0.063
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.040	0.078
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.040	0.046
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.040	0.063
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.040	0.063
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.046
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.040	0.063
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.063
THOP1	THOP1: Thimet oligopeptidase	0.040	0.046
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.046
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.040	0.372
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.063
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.063
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.040	0.372
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.038
HRB2	KRR1, HRB2: KRR1 small subunit processome component homolog	0.040	0.093
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.040	0.038
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.040	0.063
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.063
LPXN	LPXN, LDLP: Leupaxin	0.040	0.063
XPO1	XPO1, CRM1: Exportin-1	0.040	0.188
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.039	0.0425
SORL1	SORL1: Sortilin-related receptor precursor	0.039	0.032
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.038	0.063
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.029
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.038	0.046
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.038	0.038
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.046
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.038	0.233
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.038	0.188
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.038
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.038	0.086
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.038	0.139
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.038	0.046
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.038	0.038
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.087
STK10	STK10: Uncharacterized protein STK10	0.038	0.078
MAFG	MAFG: Transcription factor MafG	0.038	0.136
TCEB3	TCEB3, MSTP059: Transcription elongation factor B polypeptide 3	0.038	0.038
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.038	0.029
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.372
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.038	0.046
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.029
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.038	0.188
DDX47	E4-DBP: DEAD box protein	0.038	0.074
BAT1	N/A	0.038	0.060
DDX19A	DDX19A, DDX19L: ATP-dependent RNA helicase DDX19A	0.038	0.074
CCNG1	CCNG1, CCNG, CYCG1: Cyclin-G1	0.038	0.044
CCNA2	CCNA2, CCN1, CCNA: Cyclin-A2	0.038	0.036
DDX18	DDX18: ATP-dependent RNA helicase DDX18	0.038	0.060
EIF4A1	EIF4A1, DDX2A, EIF4A: Eukaryotic initiation factor 4A-I	0.038	0.044
ASCC3	ASCC3, HELIC1: Activating signal cointegrator 1 complex subunit 3	0.038	0.044
SAFB2	SAFB2, KIAA0138: Scaffold attachment factor B2	0.036	0.061
SRPR	SRPR: Uncharacterized protein SRPR	0.036	0.070
HD	HD, IT15: Huntingtin	0.036	0.155
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.036	0.070
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.0971
LIMS1	N/A	0.036	0.0425
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.036	0.052
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.036	0.052
IFI35	N/A	0.036	0.052
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.036	0.025
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.036	0.025
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.025
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.036	0.025
H1F0	H1F0, H1FV: Histone H1.0	0.035	0.049
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.035	0.056
SMAD7	SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7	0.034	0.077
FOXL2	FOXL2: Forkhead box protein L2	0.034	0.049
AXIN1		0.0333	0.052
YWHAG	YWHAG: 14-3-3 protein gamma	0.0333	0.028
HCK	N/A	0.033	0.029
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.033	0.046
BACH1	BACH1: Transcription regulator protein BACH1	0.032	0.251
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.032	0.0425
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.032
ID2	ID2: DNA-binding protein inhibitor ID-2	0.032	0.155
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.032
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.032	0.052
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.052
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.155
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.096
GTF3C1	N/A	0.032	0.070
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.032	0.0425
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.077
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.032	0.052
AHR	AHR: Aryl hydrocarbon receptor precursor	0.032	0.049
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.032	0.026
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.032	0.063
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.032	0.086
FRG1	FRG1: Protein FRG1	0.032	0.063
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.032	0.046
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.078
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.063
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.032	0.063
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.032	0.063
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.032	0.461
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.032	0.063
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.046
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.032	0.046
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	0.275
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.032	0.046
ACTG1	ACTB: Actin, cytoplasmic 1	0.032	0.046
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.032	0.038
FLII	FLII, FLIL: Protein flightless-1 homolog	0.032	0.046
PREP	PREP, PEP: Prolyl endopeptidase	0.032	0.063
PPARBP	N/A	0.032	0.063
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.046
CRKL	CRKL: Crk-like protein	0.032	0.063
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.046
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.275
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.032	0.087
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.046
CUL2	CUL2: Cullin-2	0.032	0.027
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.031	0.027
NFIB	N/A	0.031	0.056
RFX1	RFX1: MHC class II regulatory factor RFX1	0.0308	0.097
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.0308	0.049
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.029	0.114
METTL1	METTL1, C12orf1: tRNA	0.029	0.029
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.029	0.225
JUND	JUND: Transcription factor jun-D	0.029	0.275
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.029	0.063
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.029
CSDA	CSDA, DBPA: DNA-binding protein A	0.029	0.171
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.029	0.225
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.038
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.029	0.038
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.029	0.046
RUNX1	N/A	0.029	0.029
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.029	0.038
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.029	0.029
WDR44	WDR44: WD repeat-containing protein 44	0.029	0.029
JUNB	JUNB: Transcription factor jun-B	0.029	0.171
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.029	0.046
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.029	0.038
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.029	0.038
POLB	POLB: DNA polymerase beta	0.029	0.046
BID	BID: BH3-interacting domain death agonist	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.028	0.025
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.083
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
NF2	NF2, SCH: Merlin	0.028	0.028
HES6	HES6: Transcription cofactor HES-6	0.028	0.052
ZNF265	N/A	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.028
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.028	0.025
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.083
PRKACB	PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.028	0.025
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.083
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.083
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
C13orf8	N/A	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.165
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
PHLDB2	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.083
IRF7	N/A	0.028	0.028
WDR54	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
KIF1B	N/A	0.028	0.028
HDAC8	N/A	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
NES	N/A	0.028	0.025
SNRPB	N/A	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.028	0.025
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
MAPKAPK5	N/A	0.028	0.028
TFAP4	TFAP4: Transcription factor AP-4	0.028	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.028	0.025
CORO6	N/A	0.028	0.028
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.028	0.025
FLJ23436	N/A	0.028	0.025
DSP	DSP: Desmoplakin	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
HDAC7A	N/A	0.028	0.025
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
RFX5	RFX5: DNA-binding protein RFX5	0.0278	0.083
HIST2H2BE	HIST2H2BE, H2BFQ: Histone H2B type 2-E	0.028	4.95
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.027	0.136
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.027	0.038
IPO9	IPO9, IMP9, HSPC273, KIAA1192, RANBP9: Importin-9	0.027	0.030
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.027	0.032
MPG	N/A	0.027	0.0425
NAT1	NAT1, AAC1: Arylamine N-acetyltransferase 1	0.027	0.0425
TRADD	TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein	0.027	0.052
GAS2	GAS2: Growth arrest-specific protein 2	0.027	0.026
YWHAQ	YWHAQ: 14-3-3 protein theta	0.027	0.070
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.027	0.0425
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.026	0.026
PRKAA1	N/A	0.026	0.052
GRLF1	N/A	0.026	0.032
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.0425
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.026	0.0425
MEF2A	N/A	0.026	0.127
NUP214	N/A	0.026	0.032
MECP2	MECP2: Methyl-CpG-binding protein 2	0.026	0.0425
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.026
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.026	0.046
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.077
KRT18	KRT18: Uncharacterized protein KRT18	0.026	0.031
IFIH1	IFIH1, MDA5, RH116: Interferon-induced helicase C domain-containing protein 1	0.0255	0.060
DDX50	DDX50: ATP-dependent RNA helicase DDX50	0.0255	0.083
RECQL	RECQL, RECQL1: ATP-dependent DNA helicase Q1	0.0255	0.060
ATXN7	ATXN7, SCA7: Ataxin-7	0.0253	0.033
CIC	CIC, KIAA0306: Protein capicua homolog	0.025	0.0513
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.075
SON		0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.075
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.025
BCOR	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
KCTD1		0.025	0.025
MAPK8IP3	N/A	0.025	0.025
MAX	MAX: Protein max	0.025	0.047
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.047
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.047
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
PRKCB1	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.148
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.075
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
NUP98	N/A	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
SEC13L1	N/A	0.025	0.025
NIPBL	N/A	0.025	0.075
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.075
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.075
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
ATXN2L	N/A	0.025	0.025
ELMO1	N/A	0.025	0.047
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.075
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
GRK6	N/A	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
C20orf77	N/A	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.075
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.075
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.075
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.148
HTATIP	N/A	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
DIDO1	N/A	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.075
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.075
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
TCEA1	N/A	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.075
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.075
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025

0.299

Total Score

10.30