PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between TP53 and MCM3

The interaction score between TP53 and MCM3 is 46.90.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between TP53 and MCM3 = 0.83

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027

Orthology

Organism	TP53 Orthologue		MCM3 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
fly	Q8IH92	0.16	P91675	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in TP53 and MCM3:

Domains in TP53

Domains in MCM3

IPR008967	p53-like transcription factor, DNA-binding
IPR002117	p53 tumor antigen
IPR010991	p53, tetramerisation
IPR011615	P53_DNA_bd.
IPR012346	P53_RUNT_DNA_bd.

IPR003593	AAA ATPase
IPR008994	Nucleic acid-binding OB-fold
IPR001208	MCM
IPR008046	MCM protein 3

The Chi square scores for co-occurrence of domains that are present in TP53 and MCM3 are listed below.

Domain 1		Domain 2		Chi Square
IPR008967	p53-like transcription factor, DNA-binding	IPR008994	Nucleic acid-binding OB-fold	4.96744
IPR002117	p53 tumor antigen	IPR008994	Nucleic acid-binding OB-fold	3.49438
IPR010991	p53, tetramerisation	IPR008994	Nucleic acid-binding OB-fold	3.49438
IPR011615	P53_DNA_bd.	IPR008994	Nucleic acid-binding OB-fold	3.49438
IPR012346	P53_RUNT_DNA_bd.	IPR008994	Nucleic acid-binding OB-fold	3.49438

The background colour of the table refers to:

Blue Domain is only present in TP53
Yellow Domain is only present in MCM3
Green Domain is present in both TP53 and MCM3

0.052

Post-translational Modifications

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Protein: MCM3

PTM	Residue	Reference
Phosphorylation	713	PubMed, HPRD
Phosphorylation	722	PubMed, HPRD
Phosphoserine	535	PubMed, HPRD
Phosphothreonine	713	HPRD
Phosphothreonine	722	HPRD

Localisation

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: MCM3

Localisation	Reference
Nucleus	HPRD
Nucleoplasm	HPRD

Transitive Score

The common interactors between TP53 and MCM3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andMCM3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and MCM3 has 1106 interactors of which there are 844 common interactors.

Common Interactor	Name of Common Interactor	Score for TP53-Interactor (?)	Score for MCM3-Interactor (?)
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	4.77	0.416
H2AFX	H2AFX, H2AX: Histone H2A.x	4.27	0.129
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	2.54	0.046
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	2.08	0.225
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	1.58	0.038
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	1.58	0.038
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	1.26	0.136
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.964	0.704
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.822	0.827
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.704	0.822
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.704	0.241
PCNA	PCNA: Proliferating cell nuclear antigen	0.704	1.62
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.651	0.070
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.541	0.074
SP100	N/A	0.525	0.052
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.503	0.066
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.503	0.066
SREBF2	N/A	0.475	0.087
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.471	0.763
NBN	NBN, NBS, NBS1, P95: Nibrin	0.430	0.144
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.430	0.307
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.430	0.917
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.430	0.087
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.430	0.307
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.430	0.144
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.430	0.307
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.430	0.515
DDX21	DDX21: Nucleolar RNA helicase 2	0.430	0.430
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.425	0.063
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.385	0.276
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.385	0.385
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.385	0.385
CCNB1	Cyclin B1	0.385	40.60
SP3	SP3: Transcription factor Sp3	0.347	0.046
SRF	SRF: Serum response factor	0.344	0.063
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.318	0.275
SNRPA	SNRPA: U1 small nuclear ribonucleoprotein A	0.307	0.139
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	0.503
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.304	0.040
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.290	0.046
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.284	0.225
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.276	0.515
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.276	0.515
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.827
POLA2	POLA2: DNA polymerase subunit alpha B	0.276	0.276
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.276	0.515
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.276	0.276
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.822
CENPA	CENPA: Histone H3-like centromeric protein A	0.269	0.307
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.260	0.144
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.260	0.430
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.260	0.276
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.260	0.087
EP300	N/A	0.254	0.046
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.254	0.046
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.253	0.074
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.245	0.066
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.241	1.62
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.241	1.29E3
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.241	1.29E3
POLR2H	POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3	0.241	0.257
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.233	0.276
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.233	0.276
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.129
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.233	0.063
YY1	YY1: Transcriptional repressor protein YY1	0.233	0.078
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.233	0.146
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.227	0.423
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.216	0.038
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.216	0.043
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.210	0.063
RB1	RB1: Retinoblastoma-associated protein	0.210	0.515
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.210	0.430
ELF1	ELF1: ETS-related transcription factor Elf-1	0.210	0.416
MATR3	MATR3, KIAA0723: Matrin-3	0.210	0.163
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.208	0.029
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.188	0.188
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.233
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	0.063
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.188	0.063
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.188	0.188
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.118
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.188	0.078
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.372
CXorf9	N/A	0.188	0.046
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.188
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.188	0.038
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.187	0.047
MYB	MYB: Myb proto-oncogene protein	0.176	0.070
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.162	0.074
TP73	TP73, P73: Tumor protein p73	0.156	0.048
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.155	0.052
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.155	0.080
ZNF267	ZNF267: Zinc finger protein 267	0.155	0.052
ERF	ERF: ETS domain-containing transcription factor ERF	0.155	0.191
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.052
MITF	MITF: Microphthalmia-associated transcription factor	0.152	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.152	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.152	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.028
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.461
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.146	0.763
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.146	0.078
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.146	0.763
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.146	1.62
ABCF1	N/A	0.144	0.144
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.144
MKI67	MKI67: Antigen KI-67	0.144	0.307
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.144	0.163
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.144	0.144
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.575
ESPL1	N/A	0.144	0.307
PTMA	N/A	0.144	0.144
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.141	0.141
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.141	0.066
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.141	0.141
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.141	0.394
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.141	0.141
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.139	0.372
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.139	0.063
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.139	0.046
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.139	0.139
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.139	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.139	0.139
COPE	COPE: Coatomer subunit epsilon	0.139	0.046
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.139	0.063
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.139	0.461
RELA	RELA, NFKB3: Transcription factor p65	0.139	0.038
KIAA1012	KIAA1012: Protein TRS85 homolog	0.139	0.046
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.139	0.139
CDC23	CDC23: Cell division cycle protein 23 homolog	0.137	0.141
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.137	0.040
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.137	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.137	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.137	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.047
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.047
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.132	0.852
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.132	0.515
IRF3	IRF3: Interferon regulatory factor 3	0.132	0.307
CDK4	CDK4: Cell division protein kinase 4	0.129	0.515
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.129	0.129
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.129	0.515
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.276
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.515
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.129	0.276
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.515
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.276
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.129	0.827
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.276
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.241
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.129	0.241
RBBP4	RBBP4, RBAP48: Histone-binding protein RBBP4	0.129	0.048
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.129	0.078
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.763
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.276
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.276
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.276
LSM5	LSM5: U6 snRNA-associated Sm-like protein LSm5	0.129	0.048
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.276
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.241
NUP153	N/A	0.129	0.276
SSB	SSB: Lupus La protein	0.129	0.241
KIF11	N/A	0.129	0.276
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.129	0.241
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.515
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.129
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.276
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.276
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.052
ZNF335	ZNF335: Zinc finger protein 335	0.127	0.038
ZFX	ZFX: Zinc finger X-chromosomal protein	0.127	0.0425
HIVEP1	N/A	0.127	0.0425
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.124	0.503
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.461
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.118	0.461
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.118	0.763
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.114	0.038
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.046
ETS1	ETS1, EWSR2: Protein C-ets-1	0.114	0.171
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.114	0.038
FKBP4	FKBP4: FK506-binding protein 4	0.114	0.046
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.114	0.038
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.114	0.054
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.038
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.114	0.038
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.114	0.071
CCNH	CCNH: Cyclin-H	0.114	0.225
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.114	0.046
MTF1	MTF1: Metal regulatory transcription factor 1	0.114	0.029
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.114	0.038
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.114	0.225
AIP	AIP, XAP2: AH receptor-interacting protein	0.114	0.038
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.114	0.087
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.114	0.087
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.114	0.054
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.114	0.139
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.112	0.304
CSK	CSK: Tyrosine-protein kinase CSK	0.112	0.090
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.112	0.112
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.111	0.040
HSP90AA1	Hsp89-alpha-delta-N	0.111	0.040
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.111	0.090
STAT6	STAT6: Signal transducer and activator of transcription 6	0.111	0.054
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.102	0.043
GTF2F2	N/A	0.0971	0.251
STAT2	STAT2: Signal transducer and activator of transcription 2	0.096	0.060
NFATC1	N/A	0.096	0.032
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.096	0.188
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.096	0.032
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.093	0.066
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.087	0.163
GNB2L1	Lung cancer oncogene 7	0.087	0.087
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.132
NCOA3	N/A	0.087	0.052
SET	SET: Protein SET	0.087	0.144
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.269
TCOF1	N/A	0.087	0.144
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.163
IFI16	N/A	0.087	0.070
KIF23	N/A	0.087	0.144
DNMT1	DNMT1, AIM, DNMT: DNA	0.087	0.852
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.087	0.070
TGIF2	TGIF2: Homeobox protein TGIF2	0.087	0.087
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.087	0.144
UNG	N/A	0.087	0.276
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.087	0.070
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.087	0.063
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.087	0.372
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.087	0.372
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.087	0.029
SOX4	SOX4: Transcription factor SOX-4	0.086	0.046
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.086	0.136
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.086	0.038
BRPF1	BRPF1, BR140: Peregrin	0.086	0.029
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.086	0.071
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.086	0.029
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.086	0.029
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.086	0.114
CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1	0.086	0.097
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.086	0.114
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.086	0.029
ATM	ATM: Serine-protein kinase ATM	0.086	0.054
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.084	0.0446
PPEF1	N/A	0.083	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.052
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.083	0.028
MAPK15	N/A	0.083	0.052
C20orf18	N/A	0.083	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.165
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.083	0.028
UHRF1		0.083	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.083	0.028
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.047
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.083	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.083	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.083	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.083	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.083	0.083
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.028
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.0818	0.032
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.0818	0.032
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.081	0.028
H1FX	H1FX: Histone H1x	0.080	0.251
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.146
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.078	0.078
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.241
FNBP1	N/A	0.078	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.146
CDK2	CDK2: Cell division protein kinase 2	0.078	27.40
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.078	0.129
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.118
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.129
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.241
LIG1	LIG1: DNA ligase 1	0.078	0.276
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.078	0.515
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.078	0.276
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.078	0.129
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.078	0.129
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.078	0.129
NOL1	N/A	0.078	0.129
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.129
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.078
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.129
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.146
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.146
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.241
CDK7	CDK7, MO15: Cell division protein kinase 7	0.078	0.118
MYBL2	MYBL2, BMYB: Myb-related protein B	0.078	0.129
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.118
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.078	0.129
U2AF1	U2AF1, U2AF35, U2AFBP: Splicing factor U2AF 35 kDa subunit	0.078	0.065
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.146
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.078
RBM28	RBM28: RNA-binding protein 28	0.078	0.065
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.078
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.241
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.241
ETS2	ETS2: Protein C-ets-2	0.077	0.152
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.060
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.077	0.114
ERG	ERG: Transcriptional regulator ERG	0.077	0.251
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.077	0.032
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.077	0.060
EEF2	EEF2, EF2: Elongation factor 2	0.075	0.032
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.075	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.075	0.025
BRD4	N/A	0.075	0.025
SOX8	SOX8: Transcription factor SOX-8	0.075	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.075	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.075	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.075	0.025
GIT2	N/A	0.075	0.047
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.075	0.047
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.075	0.148
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.075	0.047
CCNT2	CCNT2: Cyclin-T2	0.075	0.148
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.075	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.148
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.075	0.075
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.075	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.075	0.075
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.075	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.075	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.148
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.148
RNF20		0.075	0.025
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.074	0.066
PHB2	PHB2, BAP, REA: Prohibitin-2	0.074	0.0446
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.074
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.071	0.225
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.070	0.132
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.070	0.087
WDR1	N/A	0.070	0.052
PLEK	PLEK, P47: Pleckstrin	0.070	0.052
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.070	0.087
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.070	0.144
STK16	N/A	0.070	0.080
KIAA0853	N/A	0.070	0.070
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.163
API5	N/A	0.070	0.087
UBAP2	N/A	0.070	0.087
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.070
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.070
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.087
ZNF551	N/A	0.069	0.038
GCN5L2	GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2	0.069	0.029
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.054
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.069	0.029
KLF1	KLF1, EKLF: Krueppel-like factor 1	0.069	0.038
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.067	0.090
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.067	0.041
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.066	0.066
HSPD1		0.066	0.141
CSE1L	CSE1L, CAS, XPO2: Exportin-2	0.066	0.033
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.141
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.066	0.066
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.245
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.141
QARS	QARS: Glutaminyl-tRNA synthetase	0.066	0.066
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.066	0.141
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.066	0.040
CTPS	CTPS: CTP synthase 1	0.066	0.141
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.141
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.141
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.066	0.040
TCP1	CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha	0.066	0.033
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.141
HNRPK	N/A	0.066	0.066
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.066	0.066
GPI	GPI: Glucose-6-phosphate isomerase	0.066	0.040
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.066
KPNB1	KPNB1, NTF97: Importin subunit beta-1	0.066	0.033
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.066	0.141
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.078
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.063
CORO1C	CORO1C, CRNN4: Coronin-1C	0.063	0.046
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.063	0.046
PPP1R8	N/A	0.063	0.129
MTA1	MTA1: Metastasis-associated protein MTA1	0.063	0.461
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.063
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.063
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.063
RPS6KB1	N/A	0.063	0.118
SEC31L1	N/A	0.063	0.046
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.063
RBM7		0.063	0.118
WBSCR20A	N/A	0.063	0.063
PHF10	N/A	0.063	0.078
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.063	0.515
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.063	0.087
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.063
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.078
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.087
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.078
MYH9	MYH9: Myosin-9	0.063	0.038
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.078
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.063	0.063
COPB2	COPB2: Coatomer subunit beta'	0.063	0.063
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.146
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.063	0.146
COPA	COPA: Coatomer subunit alpha	0.063	0.046
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.046
TIMELESS	TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog	0.063	73.00
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.078
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.063
WEE1	WEE1: Wee1-like protein kinase	0.063	0.146
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.146
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.062	0.032
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.062	0.026
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.061	0.046
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.060	0.111
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.191
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.057	0.033
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.056	0.035
PCAF	PCAF: Histone acetyltransferase PCAF	0.056	0.029
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.056	0.035
ETV1	ETV1, ER81: ETS translocation variant 1	0.056	0.110
STAT4	STAT4: Signal transducer and activator of transcription 4	0.055	0.035
SOS1	SOS1: Son of sevenless homolog 1	0.054	0.071
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.054	0.029
RPA1	RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit	0.053	0.263
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.165
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.165
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.052	0.132
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.052
CHUK	N/A	0.052	0.070
AFF1	N/A	0.052	0.052
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.070
TOP2B	N/A	0.052	0.087
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.070
EMD	EMD, EDMD, STA: Emerin	0.052	0.0425
TRRAP	N/A	0.052	0.052
ARFGAP1	N/A	0.052	0.070
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.0971
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.052
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.052
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.087
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.052
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.070
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.070
JAK1		0.051	0.033
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.051	0.033
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.051	0.041
SMARCA1	SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1	0.050	0.050
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.04
STAT3		0.049	0.036
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.04
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.049	0.0308
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.049	0.028
ELK1	ELK1: ETS domain-containing protein Elk-1	0.049	0.111
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.048	0.026
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.048	0.048
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.048	0.032
PAICS	PAICS, ADE2, AIRC, PAIS: Multifunctional protein ADE2 [Includes: Phosphoribosyla	0.0479	0.027
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.148
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.047	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.047	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.047	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.047	0.148
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.148
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.046
SAPS3	N/A	0.046	0.046
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.071
SYMPK	SYMPK, SPK: Symplekin	0.046	0.046
CUL5	CUL5, VACM1: Cullin-5	0.046	0.063
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.146
MDN1	MDN1, KIAA0301: Midasin	0.046	0.372
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.087
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.046	0.146
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.046	0.118
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.046	0.078
FZR1	N/A	0.046	0.038
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.046	63.90
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.046	0.038
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.038
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.046	0.087
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.046
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.146
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.038
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.087
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.046	0.046
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.046	0.087
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.046
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	0.078
DIAPH1	Diaphanous 1	0.046	0.046
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.046	0.038
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.046	0.071
DOK1	DOK1: Docking protein 1	0.046	0.038
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.046
KLHDC4	N/A	0.046	0.063
WDR79	N/A	0.046	0.046
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.046	0.063
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.046	0.038
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	0.087
CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol	0.046	0.046
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.071
CUL4B	N/A	0.046	0.046
GSK3B	N/A	0.046	0.038
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.046
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.046	0.087
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.046	0.126
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.0446	0.036
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.0446	0.074
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.074
TK1	TK1: Thymidine kinase, cytosolic	0.0446	0.066
FUBP1	N/A	0.0446	0.253
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.044	0.028
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.043	0.171
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.0425	0.0425
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.0425	0.080
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.052
XRCC4	N/A	0.0425	0.0425
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.032
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0425	0.052
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.0425	0.032
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.0425	0.060
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.080
SMARCC2	N/A	0.0425	0.052
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.032
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.0425	0.080
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.0425	0.026
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.080
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.0425	0.046
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.080
RGS14	N/A	0.0425	0.032
MARK2	N/A	0.0425	0.026
COIL	COIL, CLN80: Coilin	0.0425	0.0425
DHX15	DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase	0.042	0.293
HELLS	HELLS, PASG, Nbla10143, SMARCA6: Lymphoid-specific helicase	0.042	0.081
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.041	0.033
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	0.04
LCP1	LCP1, PLS2: Plastin-2	0.040	0.032
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.040	0.032
CD2AP	CD2AP: CD2-associated protein	0.040	0.040
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.040	0.040
RACGAP1	RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1	0.040	0.141
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.040	0.040
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.040	0.304
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.066
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.040	0.141
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.066
THOP1	THOP1: Thimet oligopeptidase	0.040	0.066
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.040
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.040	0.111
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.040
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.040
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.040	0.111
TRIP13	TRIP13: Thyroid receptor-interacting protein 13	0.040	0.503
HRB2	KRR1, HRB2: KRR1 small subunit processome component homolog	0.040	0.0525
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.040	0.040
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.040	0.040
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.040
LPXN	LPXN, LDLP: Leupaxin	0.040	0.032
XPO1	XPO1, CRM1: Exportin-1	0.040	0.141
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.039	0.039
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.038	0.054
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.054
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.038	0.114
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.038	0.043
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.046
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.038	0.087
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.038	0.118
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.029
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.038	0.029
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.038	0.087
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.038	0.071
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.038	0.087
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.046
STK10	STK10: Uncharacterized protein STK10	0.038	0.054
MAFG	MAFG: Transcription factor MafG	0.038	0.046
TCEB3	TCEB3, MSTP059: Transcription elongation factor B polypeptide 3	0.038	0.038
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.038	0.029
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.038
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.038	0.029
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.046
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.038	0.087
BAT1	N/A	0.038	0.038
CCNG1	CCNG1, CCNG, CYCG1: Cyclin-G1	0.038	0.123
CCNA2	CCNA2, CCN1, CCNA: Cyclin-A2	0.038	0.263
DDX18	DDX18: ATP-dependent RNA helicase DDX18	0.038	0.038
EIF4A1	EIF4A1, DDX2A, EIF4A: Eukaryotic initiation factor 4A-I	0.038	0.038
ASCC3	ASCC3, HELIC1: Activating signal cointegrator 1 complex subunit 3	0.038	0.123
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.037	0.0263
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.037	0.027
E2F5	E2F5: Transcription factor E2F5	0.036	0.036
SRPR	SRPR: Uncharacterized protein SRPR	0.036	0.202
HD	HD, IT15: Huntingtin	0.036	0.0446
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.036
LIMS1	N/A	0.036	0.027
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.036	0.027
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.036	0.036
IFI35	N/A	0.036	0.027
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.036
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.036	0.036
H1F0	H1F0, H1FV: Histone H1.0	0.035	0.046
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.035	0.097
FOXL2	FOXL2: Forkhead box protein L2	0.034	0.097
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.033	0.041
HCK	N/A	0.033	0.027
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.033	0.033
BACH1	BACH1: Transcription regulator protein BACH1	0.032	0.026
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.032	0.032
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.060
ID2	ID2: DNA-binding protein inhibitor ID-2	0.032	0.026
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.026
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.032	0.060
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.060
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.0425
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.060
GTF3C1	N/A	0.032	0.0425
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.032	0.048
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.026
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.032	0.032
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.032	0.080
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.032	0.032
FRG1	FRG1: Protein FRG1	0.032	0.040
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.090
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.032
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.032	0.032
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.032	0.090
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.032	0.040
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.032
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.032	0.040
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.032	0.032
PPARBP	N/A	0.032	0.040
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.040
CRKL	CRKL: Crk-like protein	0.032	0.040
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.040
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.066
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.032	0.032
PRDX1	PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1	0.032	0.032
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.032
CUL2	CUL2: Cullin-2	0.032	0.156
RFX1	RFX1: MHC class II regulatory factor RFX1	0.0308	0.097
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.0308	0.097
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.029	0.087
METTL1	METTL1, C12orf1: tRNA	0.029	0.038
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.029	0.029
JUND	JUND: Transcription factor jun-D	0.029	0.029
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.029	0.038
CSDA	CSDA, DBPA: DNA-binding protein A	0.029	0.225
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.054
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.029	0.043
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.029	0.046
RUNX1	N/A	0.029	0.046
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.029	0.043
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.029	0.046
TOP3A	TOP3A, TOP3: DNA topoisomerase 3-alpha	0.029	0.038
WDR44	WDR44: WD repeat-containing protein 44	0.029	0.029
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.029	0.071
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.029	0.071
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.029	0.035
POLB	POLB: DNA polymerase beta	0.029	0.029
BID	BID: BH3-interacting domain death agonist	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.052
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.052
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.052
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.028	0.047
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
NF2	NF2, SCH: Merlin	0.028	0.028
HES6	HES6: Transcription cofactor HES-6	0.028	0.028
ZNF265	N/A	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.052
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.028	0.047
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.052
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.028	0.025
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.052
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
C13orf8	N/A	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.083
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.052
PHLDB2	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.052
IRF7	N/A	0.028	0.028
WDR54	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
KIF1B	N/A	0.028	0.028
HDAC8	N/A	0.028	0.052
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.052
NES	N/A	0.028	0.025
SNRPB	N/A	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.028	0.047
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
MAPKAPK5	N/A	0.028	0.052
TFAP4	TFAP4: Transcription factor AP-4	0.028	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.028	0.047
CORO6	N/A	0.028	0.028
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.028	0.047
FLJ23436	N/A	0.028	0.025
DSP	DSP: Desmoplakin	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
HDAC7A	N/A	0.028	0.047
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
RFX5	RFX5: DNA-binding protein RFX5	0.0278	0.137
BUB3	N/A	0.027	0.027
C22orf18	N/A	0.027	0.082
SERBP1	N/A	0.027	0.027
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.027	0.027
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.027	0.073
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.027	0.027
C20orf116	C20orf116: Uncharacterized protein C20orf116 precursor	0.027	0.027
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.027	0.027
MPG	N/A	0.027	0.027
NAT1	NAT1, AAC1: Arylamine N-acetyltransferase 1	0.027	0.027
GAS2	GAS2: Growth arrest-specific protein 2	0.027	0.027
YWHAQ	YWHAQ: 14-3-3 protein theta	0.027	0.036
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.026	0.060
PRKAA1	N/A	0.026	0.048
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.032
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.026	0.048
MEF2A	N/A	0.026	0.026
MECP2	MECP2: Methyl-CpG-binding protein 2	0.026	0.026
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.026
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.026	0.029
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.026	0.035
DDX50	DDX50: ATP-dependent RNA helicase DDX50	0.0255	0.042
RECQL	RECQL, RECQL1: ATP-dependent DNA helicase Q1	0.0255	0.060
GABPB2	GABPB2, E4TF1B, GABPB, GABPB1: GA-binding protein beta chain	0.0255	0.0278
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.047
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.047
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.047
SON		0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.047
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.047
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.047
BCOR	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
KCTD1		0.025	0.025
MAPK8IP3	N/A	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.047
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.047
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.047
PRKCB1	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.047
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.047
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.047
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
NUP98	N/A	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
SEC13L1	N/A	0.025	0.025
NIPBL	N/A	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.047
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.047
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
ATXN2L	N/A	0.025	0.025
ELMO1	N/A	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
GRK6	N/A	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
C20orf77	N/A	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.148
ADK	ADK: Adenosine kinase	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.047
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.047
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.047
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.047
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.148
HTATIP	N/A	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
DIDO1	N/A	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.047
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.075
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.047
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
TCEA1	N/A	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.047
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.047
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.047
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.047
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.047
KNTC2	KNTC2, HEC, HEC1: Kinetochore protein Hec1	0.025	0.144
C11orf58	SMAP, C11orf58: Small acidic protein	0.025	0.025
PSME3	PSME3: Proteasome activator complex subunit 3	0.025	0.025
NOLC1	NOLC1, KIAA0035: Nucleolar phosphoprotein p130	0.025	0.053
PTGES3	PTGES3, P23, TEBP: Prostaglandin E synthase 3	0.025	0.053

0.228

Total Score

46.90