PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between TP53 and MAPK1

The interaction score between TP53 and MAPK1 is 10.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between TP53 and MAPK1 = 0.28

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

2.88E-3

Orthology

Organism	TP53 Orthologue		MAPK1 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
fly	Q8IH92	0.16	P40417	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in TP53 and MAPK1:

Domains in TP53

Domains in MAPK1

IPR008967	p53-like transcription factor, DNA-binding
IPR002117	p53 tumor antigen
IPR010991	p53, tetramerisation
IPR011615	P53_DNA_bd.
IPR012346	P53_RUNT_DNA_bd.

IPR000719	Protein kinase
IPR002290	Serine/threonine protein kinase
IPR011009	Protein kinase-like
IPR008271	Serine/threonine protein kinase, active site
IPR003527	MAP kinase
IPR008349	ERK1/2 MAP kinase

The Chi square scores for co-occurrence of domains that are present in TP53 and MAPK1 are listed below.

Domain 1		Domain 2		Chi Square
IPR008967	p53-like transcription factor, DNA-binding	IPR003527	MAP kinase	13.3166
IPR002117	p53 tumor antigen	IPR008271	Serine/threonine protein kinase, active site	4.60701
IPR010991	p53, tetramerisation	IPR008271	Serine/threonine protein kinase, active site	4.60701
IPR011615	P53_DNA_bd.	IPR008271	Serine/threonine protein kinase, active site	4.60701
IPR012346	P53_RUNT_DNA_bd.	IPR008271	Serine/threonine protein kinase, active site	4.60701
IPR012346	P53_RUNT_DNA_bd.	IPR003527	MAP kinase	4.12115
IPR011615	P53_DNA_bd.	IPR003527	MAP kinase	4.12115
IPR010991	p53, tetramerisation	IPR003527	MAP kinase	4.12115
IPR002117	p53 tumor antigen	IPR003527	MAP kinase	4.12115
IPR012346	P53_RUNT_DNA_bd.	IPR002290	Serine/threonine protein kinase	3.23646
IPR011615	P53_DNA_bd.	IPR002290	Serine/threonine protein kinase	3.23646
IPR010991	p53, tetramerisation	IPR002290	Serine/threonine protein kinase	3.23646
IPR002117	p53 tumor antigen	IPR002290	Serine/threonine protein kinase	3.23646
IPR008967	p53-like transcription factor, DNA-binding	IPR008349	ERK1/2 MAP kinase	2.09064
IPR008967	p53-like transcription factor, DNA-binding	IPR002290	Serine/threonine protein kinase	1.43889
IPR008967	p53-like transcription factor, DNA-binding	IPR008271	Serine/threonine protein kinase, active site	0.974716
IPR008967	p53-like transcription factor, DNA-binding	IPR000719	Protein kinase	0.163761
IPR012346	P53_RUNT_DNA_bd.	IPR011009	Protein kinase-like	0.00633063
IPR011615	P53_DNA_bd.	IPR011009	Protein kinase-like	0.00633063
IPR002117	p53 tumor antigen	IPR011009	Protein kinase-like	0.00633063
IPR010991	p53, tetramerisation	IPR011009	Protein kinase-like	0.00633063
IPR008967	p53-like transcription factor, DNA-binding	IPR011009	Protein kinase-like	0.00476462
IPR011615	P53_DNA_bd.	IPR000719	Protein kinase	0.000322699
IPR010991	p53, tetramerisation	IPR000719	Protein kinase	0.000322699
IPR002117	p53 tumor antigen	IPR000719	Protein kinase	0.000322699
IPR012346	P53_RUNT_DNA_bd.	IPR000719	Protein kinase	0.000322699

The background colour of the table refers to:

Blue Domain is only present in TP53
Yellow Domain is only present in MAPK1
Green Domain is present in both TP53 and MAPK1

0.083

Post-translational Modifications

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Protein: MAPK1

PTM	Residue	Reference
Acetylation	2	PubMed, HPRD
Dephosphorylation	187	PubMed, HPRD
N-acetylalanine	1	HPRD
Phosphorylation	29	PubMed, HPRD
Phosphorylation	41	PubMed, HPRD
Phosphorylation	181	PubMed, HPRD
Phosphorylation	185	PubMed, HPRD
Phosphorylation	187	PubMed, HPRD
Phosphorylation	202	PubMed, HPRD
Phosphothreonine	184	PubMed, HPRD
Phosphotyrosine	186	HPRD

Localisation

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: MAPK1

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Transitive Score

The common interactors between TP53 and MAPK1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andMAPK1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and MAPK1 has 1694 interactors of which there are 919 common interactors.

Common Interactor	Name of Common Interactor	Score for TP53-Interactor (?)	Score for MAPK1-Interactor (?)
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	4.77	0.026
H2AFX	H2AFX, H2AX: Histone H2A.x	4.27	0.029
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	2.54	0.063
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	2.08	0.139
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	1.58	0.069
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	1.58	0.029
SMAD4	SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4	1.58	0.086
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	1.26	0.049
PGR	PGR, NR3C3: Progesterone receptor	1.00	0.049
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.964	0.208
NR4A2	NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2	0.902	0.069
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.822	0.087
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.704	0.344
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.704	0.063
PCNA	PCNA: Proliferating cell nuclear antigen	0.704	0.029
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.651	0.210
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.541	0.052
SP100	N/A	0.525	0.0971
MCM3	MCM3: DNA replication licensing factor MCM3	0.515	0.071
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.503	3.35
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.503	0.046
SREBF2	N/A	0.475	0.0425
NBN	NBN, NBS, NBS1, P95: Nibrin	0.430	0.0971
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.430	0.032
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.430	0.052
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.430	0.052
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.430	0.096
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.430	0.052
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.430	0.096
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.430	0.029
DDX21	DDX21: Nucleolar RNA helicase 2	0.430	0.052
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.425	0.087
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.385	0.071
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.385	0.063
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.385	0.046
CCNB1	Cyclin B1	0.385	0.136
SP3	SP3: Transcription factor Sp3	0.347	0.046
SRF	SRF: Serum response factor	0.344	0.046
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.318	0.171
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	0.063
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.304	0.046
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.290	0.139
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.284	0.136
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.276	0.038
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.276	0.046
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.276	0.038
POLA2	POLA2: DNA polymerase subunit alpha B	0.276	0.029
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.276	0.063
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.276	0.071
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.046
CENPA	CENPA: Histone H3-like centromeric protein A	0.269	0.026
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.260	0.052
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.260	0.070
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.260	0.0971
EP300	N/A	0.254	0.063
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.253	0.127
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.245	0.046
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.241	0.046
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.241	0.054
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.241	0.029
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.233	0.063
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.233	0.063
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.063
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.233	2.17
YY1	YY1: Transcriptional repressor protein YY1	0.233	0.063
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.233	0.063
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.227	0.139
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.216	0.046
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.216	0.046
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.210	0.046
RB1	RB1: Retinoblastoma-associated protein	0.210	0.127
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.210	0.032
ELF1	ELF1: ETS-related transcription factor Elf-1	0.210	0.416
MATR3	MATR3, KIAA0723: Matrin-3	0.210	0.087
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.208	0.114
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.188	0.078
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.063
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	0.139
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.188	0.038
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.188	0.046
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.038
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.188	0.063
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.188
CXorf9	N/A	0.188	0.188
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.063
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.188	0.038
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.187	0.148
MYB	MYB: Myb proto-oncogene protein	0.176	0.077
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.172	0.114
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.172	0.111
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.162	0.096
TP73	TP73, P73: Tumor protein p73	0.156	0.055
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.156	0.062
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.155	0.070
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.155	0.210
ZNF267	ZNF267: Zinc finger protein 267	0.155	0.0425
ERF	ERF: ETS domain-containing transcription factor ERF	0.155	0.152
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.0425
MITF	MITF: Microphthalmia-associated transcription factor	0.152	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.152	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.152	0.083
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.174
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.118
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.146	0.038
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.146	0.233
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.146	0.046
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.146	0.043
PPP2CA	PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	0.145	0.046
ABCF1	N/A	0.144	0.070
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.052
MKI67	MKI67: Antigen KI-67	0.144	0.048
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.144	0.127
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.144	0.251
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.070
ESPL1	N/A	0.144	0.026
PTMA	N/A	0.144	0.0971
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.141	0.029
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.141	0.046
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.141	0.275
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.141	0.038
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.141	0.275
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.140	0.0425
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.140	0.035
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.139	0.225
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.139	0.043
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.139	0.029
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.139	0.038
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.139	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.139	0.078
COPE	COPE: Coatomer subunit epsilon	0.139	0.046
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.139	0.063
RELA	RELA, NFKB3: Transcription factor p65	0.139	0.086
KIAA1012	KIAA1012: Protein TRS85 homolog	0.139	0.078
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.139	0.063
CDC23	CDC23: Cell division cycle protein 23 homolog	0.137	0.046
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.137	0.078
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.137	0.075
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.137	0.148
LMNA	LMNA, LMN1: Lamin-A/C	0.137	0.047
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.137
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.137
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.132	0.048
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.132	0.123
IRF3	IRF3: Interferon regulatory factor 3	0.132	0.080
CDK4	CDK4: Cell division protein kinase 4	0.129	0.069
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.129	0.038
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.129	0.188
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.038
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.063
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.046
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.129	0.038
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.129	0.029
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.129	0.029
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.046
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.129	0.233
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.129	0.038
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.129	0.038
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.046
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.046
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.063
NPM1	NPM1, NPM: Nucleophosmin	0.129	0.086
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.029
NUP153	N/A	0.129	0.063
SSB	SSB: Lupus La protein	0.129	0.046
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.129	0.046
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.086
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.038
CDC20	CDC20: Cell division cycle protein 20 homolog	0.129	0.069
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.129	0.029
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.0425
ZNF335	ZNF335: Zinc finger protein 335	0.127	0.038
ZFX	ZFX: Zinc finger X-chromosomal protein	0.127	0.032
HIVEP1	N/A	0.127	0.032
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.114
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.118	0.188
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.118	0.043
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.114	0.078
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.046
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.114	94.70
ETS1	ETS1, EWSR2: Protein C-ets-1	0.114	0.275
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.114	0.129
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.114	0.461
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.029
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.114	0.038
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.114	0.233
CCNH	CCNH: Cyclin-H	0.114	0.225
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.114	0.063
MTF1	MTF1: Metal regulatory transcription factor 1	0.114	0.046
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.114	0.372
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.114	0.372
AIP	AIP, XAP2: AH receptor-interacting protein	0.114	0.029
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.114	0.078
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.114	0.029
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.114	0.275
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.114	0.049
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.114	0.046
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.112	0.038
CSK	CSK: Tyrosine-protein kinase CSK	0.112	0.372
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.112	0.275
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.111	0.029
HSP90AA1	Hsp89-alpha-delta-N	0.111	3.95
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.111	0.461
STAT6	STAT6: Signal transducer and activator of transcription 6	0.111	0.372
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.102	0.046
GTF2F2	N/A	0.0971	0.060
STAT2	STAT2: Signal transducer and activator of transcription 2	0.096	0.191
NFATC1	N/A	0.096	0.096
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.096	0.416
PDK1	PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu	0.094	0.035
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.093	0.063
TCF7L2	N/A	0.090	0.026
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.087	0.127
GNB2L1	Lung cancer oncogene 7	0.087	0.0425
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.070
NCOA3	N/A	0.087	0.052
SET	SET: Protein SET	0.087	0.052
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.052
TCOF1	N/A	0.087	0.0425
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.052
IFI16	N/A	0.087	0.087
KIF23	N/A	0.087	0.026
DNMT1	DNMT1, AIM, DNMT: DNA	0.087	0.0425
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.087	0.416
TGIF2	TGIF2: Homeobox protein TGIF2	0.087	0.032
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.087	0.307
UNG	N/A	0.087	0.029
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.087	0.096
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.087	0.038
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.087	0.118
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.087	0.086
SOX4	SOX4: Transcription factor SOX-4	0.086	0.043
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.086	0.139
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.086	0.046
BRPF1	BRPF1, BR140: Peregrin	0.086	0.046
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.086	0.029
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.086	0.046
CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1	0.086	0.088
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.086	0.046
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.086	0.139
CREBBP	CREBBP, CBP: CREB-binding protein	0.086	0.038
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.086	0.038
ATM	ATM: Serine-protein kinase ATM	0.086	0.139
GHR	GHR: Growth hormone receptor precursor	0.085	0.037
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.084	0.052
PPEF1	N/A	0.083	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.083	0.028
MAPK15	N/A	0.083	0.083
C20orf18	N/A	0.083	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.165
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.083	0.028
UHRF1		0.083	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.083	0.028
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.148
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.083	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.083
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.083	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.083	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.083	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.083	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.083
NAPG	NAPG, SNAPG: Gamma-soluble NSF attachment protein	0.0818	0.046
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.0818	0.056
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.0818	0.063
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.081	0.069
H1FX	H1FX: Histone H1x	0.080	0.155
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.046
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.078	4.15
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.063
FNBP1	N/A	0.078	0.188
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.063
CDK2	CDK2: Cell division protein kinase 2	0.078	6.80
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.078	0.038
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.046
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.038
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.063
LIG1	LIG1: DNA ligase 1	0.078	0.029
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.078	0.063
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.078	0.046
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.078	0.063
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.078	0.054
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.078	7.38
NOL1	N/A	0.078	0.038
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	11.60
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.078
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.063
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.056
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.139
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.063
CDK7	CDK7, MO15: Cell division protein kinase 7	0.078	0.086
MYBL2	MYBL2, BMYB: Myb-related protein B	0.078	0.029
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.139
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.078	0.086
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.139
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.063
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.038
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.063
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.063
ETS2	ETS2: Protein C-ets-2	0.077	0.152
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.096
ERG	ERG: Transcriptional regulator ERG	0.077	0.123
MDM4	MDM4, MDMX: Mdm4 protein	0.077	0.062
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.077	0.032
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.077	0.087
EEF2	EEF2, EF2: Elongation factor 2	0.075	0.038
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.075	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.075	0.025
BRD4	N/A	0.075	0.025
SOX8	SOX8: Transcription factor SOX-8	0.075	0.047
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.075	62.30
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.075	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.075	0.025
GIT2	N/A	0.075	0.075
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.075	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.075	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.075	0.025
CCNT2	CCNT2: Cyclin-T2	0.075	0.148
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	62.30
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.075	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.075
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.075	0.025
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.075	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.075	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.075	0.025
PTP4A3	PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3	0.075	0.050
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	62.30
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.075	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.148
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.148
RNF20		0.075	0.025
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.074	0.152
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.074	0.046
PHB2	PHB2, BAP, REA: Prohibitin-2	0.074	0.026
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.026
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.071	0.114
PTPN1	PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1	0.071	0.073
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.070	0.210
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.070	0.0425
WDR1	N/A	0.070	0.070
PLEK	PLEK, P47: Pleckstrin	0.070	0.515
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.070	0.026
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.070	0.026
STK16	N/A	0.070	0.077
KIAA0853	N/A	0.070	0.070
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.052
API5	N/A	0.070	0.052
UBAP2	N/A	0.070	0.032
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.070	0.032
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.070
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.087
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.069	0.029
PTP4A1	PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1	0.069	0.046
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.069
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.069	0.029
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.069	0.461
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.069	0.029
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.069	115.00
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.069	0.275
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.067	0.063
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.067	0.225
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.067	0.086
SYK	SYK: Tyrosine-protein kinase SYK	0.067	0.275
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.066	0.078
HSPD1		0.066	6.11
CSE1L	CSE1L, CAS, XPO2: Exportin-2	0.066	0.029
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.086
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.066	0.233
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.038
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.071
QARS	QARS: Glutaminyl-tRNA synthetase	0.066	0.046
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.066	0.046
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.066	0.046
CTPS	CTPS: CTP synthase 1	0.066	0.086
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.038
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.069
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.066	0.063
TCP1	CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha	0.066	0.038
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.038
HNRPK	N/A	0.066	0.078
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.066	0.225
GPI	GPI: Glucose-6-phosphate isomerase	0.066	0.029
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.038
KPNB1	KPNB1, NTF97: Importin subunit beta-1	0.066	0.063
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.029
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.029
CORO1C	CORO1C, CRNN4: Coronin-1C	0.063	0.046
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.063	0.233
PPP1R8	N/A	0.063	0.118
MTA1	MTA1: Metastasis-associated protein MTA1	0.063	0.086
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.063
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.372
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.038
RPS6KB1	N/A	0.063	0.188
SEC31L1	N/A	0.063	0.046
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.078
RBM7		0.063	0.029
WBSCR20A	N/A	0.063	0.038
PHF10	N/A	0.063	0.038
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.063	0.114
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.063	0.225
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	0.188
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.063	0.038
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.063
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.046
MYH9	MYH9: Myosin-9	0.063	0.038
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.063	0.038
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.063	0.078
COPB2	COPB2: Coatomer subunit beta'	0.063	0.038
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.038
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.063	0.069
COPA	COPA: Coatomer subunit alpha	0.063	0.063
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.046
RAB8A	RAB8A: RAB8A protein	0.063	0.039
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.078
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.063
WEE1	WEE1: Wee1-like protein kinase	0.063	0.056
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.188
CRLF3	N/A	0.063	0.036
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.062	0.052
SH3BP3		0.062	0.0425
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.062	0.055
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.062	0.026
PTPN2	PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2	0.062	0.098
LYN	LYN: Tyrosine-protein kinase Lyn	0.061	0.372
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.061	0.251
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.061	0.152
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.060	0.035
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.060
FAM82B	FAM82B, CGI-90: Protein FAM82B	0.057	0.376
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.057	0.032
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.057	0.086
MYCBP2	MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2	0.056	0.111
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.056	0.114
PCAF	PCAF: Histone acetyltransferase PCAF	0.056	0.046
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.056	0.136
SP1	SP1, TSFP1: Transcription factor Sp1	0.056	0.029
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.056	0.069
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.056	0.097
ETV1	ETV1, ER81: ETS translocation variant 1	0.056	0.098
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.0554	0.146
STAT4	STAT4: Signal transducer and activator of transcription 4	0.055	0.225
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.055	0.109
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.054	0.078
SOS1	SOS1: Son of sevenless homolog 1	0.054	0.225
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.054	0.056
SUPT5H	SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5	0.054	0.054
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.052
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.052
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.052	0.0425
CHUK	N/A	0.052	0.052
AFF1	N/A	0.052	0.032
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.052
TOP2B	N/A	0.052	0.070
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.0425
EMD	EMD, EDMD, STA: Emerin	0.052	0.026
TRRAP	N/A	0.052	0.026
ARFGAP1	N/A	0.052	0.155
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.307
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.070
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.070
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.052
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.070
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.070
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.070
JAK1		0.051	0.461
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.051	0.056
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.051	0.372
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.051	0.171
RNF11	RNF11, CGI-123: RING finger protein 11	0.050	0.038
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.083
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.049	0.165
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.049	0.028
STAT3		0.049	0.148
NASP	NASP: Nuclear autoantigenic sperm protein	0.049	0.028
S100A16	S100A16, AAG13: Protein S100-A16	0.049	0.028
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.083
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.049	0.111
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.049	153.00
ELK1	ELK1: ETS domain-containing protein Elk-1	0.049	0.111
SOX11	SOX11: Transcription factor SOX-11	0.049	0.0308
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.048	0.127
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.048	0.062
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.048	0.055
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.047
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.047	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.047	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.047	0.075
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.047	0.075
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.025
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.188
SAPS3	N/A	0.046	0.046
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.233
SYMPK	SYMPK, SPK: Symplekin	0.046	0.029
CUL5	CUL5, VACM1: Cullin-5	0.046	0.063
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.046
MDN1	MDN1, KIAA0301: Midasin	0.046	0.038
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.139
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.046	0.056
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.046	0.069
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.046	0.038
FZR1	N/A	0.046	0.029
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.046	0.086
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.046	0.078
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.063
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.046	0.275
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.046
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.063
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.046
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.029
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.046	0.038
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.046	0.139
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.063
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	0.071
DIAPH1	Diaphanous 1	0.046	20.60
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.046	0.078
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.046	0.069
DOK1	DOK1: Docking protein 1	0.046	0.275
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.078
KLHDC4	N/A	0.046	0.078
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.046	0.029
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.046	0.029
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	0.233
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.275
CUL4B	N/A	0.046	0.063
GSK3B	N/A	0.046	0.063
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.046	0.385
PPP2CB	PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	0.0462	0.029
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.046	0.077
HSP90B1	HSP90B1, TRA1: Endoplasmin precursor	0.046	0.056
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.0453	0.048
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.0453	0.0425
APEH	APEH, D3F15S2, D3S48E, DNF15S2: Acylamino-acid-releasing enzyme	0.0446	0.038
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.0446	0.191
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.0446	0.048
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.032
FUBP1	N/A	0.0446	0.052
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.044	0.044
DUSP3	DUSP3, VHR: Dual specificity protein phosphatase 3	0.044	0.975
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.044	0.148
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.044	0.025
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.043	0.046
VDR	VDR, NR1I1: Vitamin D3 receptor	0.043	0.069
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.043	0.054
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.0425	0.026
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.0425	0.096
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.070
XRCC4	N/A	0.0425	0.032
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.052
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0425	0.032
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.0425	0.055
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.0425	0.096
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.0425	0.210
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.127
SMARCC2	N/A	0.0425	0.0425
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.052
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.0425	0.155
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.0425	0.307
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.077
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.0425	0.071
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.032
RGS14	N/A	0.0425	0.070
MARK2	N/A	0.0425	0.070
COIL	COIL, CLN80: Coilin	0.0425	0.032
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.041	0.372
EXOC2	N/A	0.041	0.063
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.041	0.038
STUB1	STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1	0.041	0.038
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	0.165
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	0.165
LCP1	LCP1, PLS2: Plastin-2	0.040	0.078
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.040	0.129
CD2AP	CD2AP: CD2-associated protein	0.040	0.139
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.040	0.063
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.040	0.063
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.040	0.046
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.038
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.040	2.02
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.372
THOP1	THOP1: Thimet oligopeptidase	0.040	0.029
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.029
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.040	0.063
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.038
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.046
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.040	0.046
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.040	0.029
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.040	0.038
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.038
LPXN	LPXN, LDLP: Leupaxin	0.040	0.046
XPO1	XPO1, CRM1: Exportin-1	0.040	0.046
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.039	0.026
PPARG	CREB3L2-PPARgamma	0.039	0.049
SORL1	SORL1: Sortilin-related receptor precursor	0.039	0.032
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.039	0.075
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.038	0.233
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.114
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.038	0.029
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.038	0.188
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.233
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.038	0.129
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.038	0.046
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.038
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.038	0.029
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.038	0.038
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.038	0.086
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.038	0.139
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.029
STK10	STK10: Uncharacterized protein STK10	0.038	0.385
MAFG	MAFG: Transcription factor MafG	0.038	0.275
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.038	0.029
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.029
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.038	0.046
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.038	0.029
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.038	0.078
CCNG1	CCNG1, CCNG, CYCG1: Cyclin-G1	0.038	0.028
CCNA2	CCNA2, CCN1, CCNA: Cyclin-A2	0.038	0.028
DDX18	DDX18: ATP-dependent RNA helicase DDX18	0.038	0.179
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.037	0.098
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.037	0.111
SRPR	SRPR: Uncharacterized protein SRPR	0.036	0.052
HD	HD, IT15: Huntingtin	0.036	0.155
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.036	0.132
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.0425
LIMS1	N/A	0.036	0.052
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.036	0.251
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.036	0.077
IFI35	N/A	0.036	0.070
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.036	0.025
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.036	0.075
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	0.148
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.036	0.148
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.035	0.044
SMAD7	SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7	0.034	0.096
FOXL2	FOXL2: Forkhead box protein L2	0.034	0.028
PTPRR	PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor	0.034	0.109
PTPRS	PTPRS: Receptor-type tyrosine-protein phosphatase S precursor	0.034	0.109
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.034	0.049
TRPV1	TRPV1: Vanilloid receptor variant TRPV1b	0.034	0.049
IL6ST	IL6ST: Interleukin-6 receptor subunit beta precursor	0.034	0.049
IL4R	IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor	0.034	0.049
LEPR	LEPR, DB, OBR: Leptin receptor precursor	0.034	0.049
TRPV4	TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb	0.034	0.049
IL6R	IL6R: Interleukin-6 receptor alpha chain precursor	0.034	0.034
PTPRC	PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ	0.034	0.098
PTPRE	PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor	0.034	0.098
AXIN1		0.0333	0.028
YWHAG	YWHAG: 14-3-3 protein gamma	0.0333	0.028
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.033	0.097
HCK	N/A	0.033	0.275
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.033	0.372
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.032	0.110
BACH1	BACH1: Transcription regulator protein BACH1	0.032	0.251
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.032	0.052
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.155
ID2	ID2: DNA-binding protein inhibitor ID-2	0.032	0.430
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.032	0.026
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.032	0.127
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.127
VIM	VIM: Vimentin	0.032	0.060
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.032	0.052
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.032
GTF3C1	N/A	0.032	0.070
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.032	0.096
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.049
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.032	0.191
AHR	AHR: Aryl hydrocarbon receptor precursor	0.032	0.086
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.032	0.127
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.032	0.063
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.032	0.029
FRG1	FRG1: Protein FRG1	0.032	0.063
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.032	0.188
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.139
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.114
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.032	0.038
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.032	0.372
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.032	0.038
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.032	0.233
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.029
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.032	0.071
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	0.038
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.032	0.114
ACTG1	ACTB: Actin, cytoplasmic 1	0.032	0.063
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.032	0.118
FLII	FLII, FLIL: Protein flightless-1 homolog	0.032	0.046
PLD1	PLD1: Phospholipase D1	0.032	0.097
PREP	PREP, PEP: Prolyl endopeptidase	0.032	0.046
PPARBP	N/A	0.032	0.063
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.032	0.046
CRKL	CRKL: Crk-like protein	0.032	0.461
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.372
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.046
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.032	0.233
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.063
CUL2	CUL2: Cullin-2	0.032	0.032
NR1D1	NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1	0.031	0.056
FLT3	FLT3, STK1: FL cytokine receptor precursor	0.031	0.041
EPOR	EPOR: Erythropoietin receptor precursor	0.031	0.0453
IL12B	IL12B, NKSF2: Interleukin-12 subunit beta precursor	0.031	0.025
MPL	MPL, TPOR: Thrombopoietin receptor precursor	0.031	0.037
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.031	0.153
NFIB	N/A	0.031	0.049
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.031	0.044
RFX1	RFX1: MHC class II regulatory factor RFX1	0.0308	0.028
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.0308	0.049
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	0.031	0.123
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.030	0.098
TRPV6	TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6	0.030	0.044
SEL1L	SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor	0.030	0.070
FKBP8	DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment)	0.029	0.029
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.029	0.038
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.029	0.225
JUND	JUND: Transcription factor jun-D	0.029	0.372
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.029	0.038
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.029
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.029	0.225
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.114
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.029	0.114
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.029	0.046
RUNX1	N/A	0.029	0.029
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.029	0.139
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.029	0.029
WDR44	WDR44: WD repeat-containing protein 44	0.029	0.046
JUNB	JUNB: Transcription factor jun-B	0.029	0.275
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.029	0.114
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.029	0.139
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.029	0.086
POLB	POLB: DNA polymerase beta	0.029	0.029
COL5A2	COL5A2: Collagen alpha-2(V) chain precursor	0.029	0.029
COL1A2	COL1A2: Collagen alpha-2(I) chain precursor	0.029	0.029
BID	BID: BH3-interacting domain death agonist	0.028	0.165
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.083
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.083
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.083
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.028	0.075
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
NF2	NF2, SCH: Merlin	0.028	0.165
HES6	HES6: Transcription cofactor HES-6	0.028	0.083
ZNF265	N/A	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.083
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.028	0.075
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.028	0.025
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
C13orf8	N/A	0.028	0.028
DUSP15	N/A	0.028	0.028
RAB4A	N/A	0.028	0.052
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.083
PHLDB2	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.165
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
IRF7	N/A	0.028	0.028
WDR54	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
KIF1B	N/A	0.028	0.028
HDAC8	N/A	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.083
NES	N/A	0.028	0.025
SNRPB	N/A	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.028	0.075
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
MAPKAPK5	N/A	0.028	0.083
TFAP4	TFAP4: Transcription factor AP-4	0.028	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.028	0.075
CORO6	N/A	0.028	0.028
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.028	0.075
FLJ23436	N/A	0.028	0.025
DSP	DSP: Desmoplakin	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
CABLES1	N/A	0.028	0.028
HDAC7A	N/A	0.028	0.025
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
NR4A1	CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor	0.028	0.050
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.027	0.111
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.027	0.029
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.027	0.088
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.027	0.275
CAPNS1	CAPNS1, CAPN4, CAPNS: Calpain small subunit 1	0.027	0.070
GSTP1	GSTP1, FAEES3, GST3: Glutathione S-transferase P	0.027	0.029
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.027	0.0425
MPG	N/A	0.027	0.0425
NAT1	NAT1, AAC1: Arylamine N-acetyltransferase 1	0.027	0.032
TRADD	TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein	0.027	0.155
LASP1	LASP1, MLN50: LIM and SH3 domain protein 1	0.027	0.260
YWHAQ	YWHAQ: 14-3-3 protein theta	0.027	0.052
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.027	0.096
BMX	N/A	0.0263	0.110
TH	TH, TYH: Tyrosine 3-monooxygenase	0.026	0.046
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.026	0.062
PRKAA1	N/A	0.026	0.077
GRLF1	N/A	0.026	0.062
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.026
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.026	0.155
MEF2A	N/A	0.026	0.052
NUP214	N/A	0.026	0.0425
ZFP36	ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline	0.026	0.038
MECP2	MECP2: Methyl-CpG-binding protein 2	0.026	0.052
TERT	TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase	0.026	0.056
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.026	0.078
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.026	0.056
KRT18	KRT18: Uncharacterized protein KRT18	0.026	0.031
ITGB4	N/A	0.025	0.032
IL9R	IL9R: Interleukin-9 receptor precursor	0.025	0.032
IL12RB2	IL12RB2: Interleukin-12 receptor beta-2 chain precursor	0.025	0.057
IFNAR1	IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor	0.025	0.037
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.075
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.075
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
SON		0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.148
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.075
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.148
BCOR	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.047
KCTD1		0.025	0.025
MAPK8IP3	N/A	0.025	0.025
MAX	MAX: Protein max	0.025	0.075
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.075
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.075
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.075
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.075
PRKCB1	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.148
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.075
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.075
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.075
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
NUP98	N/A	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
SEC13L1	N/A	0.025	0.025
NIPBL	N/A	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
ATXN2L	N/A	0.025	0.025
ELMO1	N/A	0.025	0.148
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
GRK6	N/A	0.025	0.025
RAB1B	RAB1B: Ras-related protein Rab-1B	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
C20orf77	N/A	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.075
ADK	ADK: Adenosine kinase	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.075
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.075
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.075
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.148
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.075
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
HTATIP	N/A	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
DIDO1	N/A	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
TCEA1	N/A	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.075
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.075
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.075
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.075

0.299

Total Score

10.30