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Evidence of Interaction Between TP53 and RAN

The interaction score between TP53 and RAN is 9.17.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TP53 and RAN = 0.78

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.013
Orthology
OrganismTP53 OrthologueRAN OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly Q8IH92 0.16 Q9VZ23 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains No domains were used in calculating likelihood of interaction 0.014
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: RAN

PTMResidueReference
Phosphotyrosine 147 HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: RAN

LocalisationReference
Nucleus HPRD
Mitochondrion HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and RAN that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andRAN. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and RAN has 1090 interactors of which there are 542 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for RAN-Interactor (?)
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.77 0.025
H2AFX H2AFX, H2AX: Histone H2A.x 4.27 0.066
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 1.58 0.090
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 0.141
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.141
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.704
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.704 0.040
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.066
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.027
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.541 0.430
MCM3 MCM3: DNA replication licensing factor MCM3 0.515 0.141
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.503 0.048
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.503 0.078
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.040
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.340
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.157
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.917
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.074
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.074
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 0.066
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.074
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.425 0.040
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.066
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.040
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.066
CCNB1 Cyclin B1 0.385 0.141
SRF SRF: Serum response factor 0.344 0.032
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 0.307 0.033
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.304 0.078
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.141
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.276 0.066
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.423
POLA2 POLA2: DNA polymerase subunit alpha B 0.276 0.066
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.066
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.276 0.066
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.276 0.066
CENPA CENPA: Histone H3-like centromeric protein A 0.269 0.074
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.0446
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.260 0.066
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.036
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.253 0.307
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.241 0.141
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.241 0.066
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.241 0.141
POLR2H POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3 0.241 0.033
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.066
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.066
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.241
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.233 0.063
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.032
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.032
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.227 0.048
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.032
RB1 RB1: Retinoblastoma-associated protein 0.210 0.0446
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.074
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.027
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.0446
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.111
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.188
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.188 0.032
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.040
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.032
CXorf9 N/A 0.188 0.071
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.032
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.162 0.052
ZNF267 ZNF267: Zinc finger protein 267 0.155 0.027
XRCC1 XRCC1: DNA-repair protein XRCC1 0.155 0.027
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.0333
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.146 0.040
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.146 0.276
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.146 0.304
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.146 0.033
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.146 0.066
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.145 0.046
ABCF1 N/A 0.144 0.144
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.144
MKI67 MKI67: Antigen KI-67 0.144 0.074
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.144 0.210
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.157
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.157
ESPL1 N/A 0.144 0.307
PTMA N/A 0.144 0.0446
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.141 0.129
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.141 0.827
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.141 0.129
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.141 0.276
SAT SAT1, SAT: Diamine acetyltransferase 1 0.140 0.026
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.114
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.040
COPE COPE: Coatomer subunit epsilon 0.139 0.027
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.032
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.038
CDC23 CDC23: Cell division cycle protein 23 homolog 0.137 0.241
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.137 0.045
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.030
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.030
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.132 0.0446
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.132 0.052
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.166
CDK4 CDK4: Cell division protein kinase 4 0.129 0.515
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.129 0.040
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.515
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.066
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.129 0.066
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.129 0.141
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.129 0.141
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.129 0.141
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.141
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.129 0.066
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.040
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.146
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.129 0.033
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.129 0.141
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.141
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.066
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.141
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 0.066
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 0.129 0.033
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.141
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.129 0.141
NUP153 N/A 0.129 17.50
SSB SSB: Lupus La protein 0.129 0.141
KIF11 N/A 0.129 0.066
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.141
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.241
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.141
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.066
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.078
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.118 0.040
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.118 0.372
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.118 0.066
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.139
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.139
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.114 0.029
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.114 0.171
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.139
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.086
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.114
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.114 0.038
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.114 0.029
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.114 0.071
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.112 0.129
CSK CSK: Tyrosine-protein kinase CSK 0.112 0.063
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.112 0.372
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.111 0.045
HSP90AA1 Hsp89-alpha-delta-N 0.111 0.078
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.111 0.046
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.038
GTF2F2 N/A 0.0971 0.027
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.111
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.093 0.129
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.087 0.269
GNB2L1 Lung cancer oncogene 7 0.087 0.0446
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.036
NCOA3 N/A 0.087 0.027
SET SET: Protein SET 0.087 0.157
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.0446
TCOF1 N/A 0.087 0.074
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.074
IFI16 N/A 0.087 0.036
KIF23 N/A 0.087 0.0446
DNMT1 DNMT1, AIM, DNMT: DNA 0.087 0.074
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.087 0.027
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.074
UNG N/A 0.087 0.040
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.087 0.036
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.087 0.040
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.087 0.063
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.087 0.063
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.087 0.113
BRPF1 BRPF1, BR140: Peregrin 0.086 0.029
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.071
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.086 0.071
ATM ATM: Serine-protein kinase ATM 0.086 0.069
GHR GHR: Growth hormone receptor precursor 0.085 0.027
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.084 0.087
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.052
MAPK15 N/A 0.083 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.025
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.028
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.0818 0.046
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.046
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.078 0.040
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.040
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.040
FNBP1 N/A 0.078 0.139
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.078 0.066
CDK2 CDK2: Cell division protein kinase 2 0.078 0.241
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.078 0.040
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.040
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.066
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 0.078 0.033
CYCS CYCS, CYC: Cytochrome c 0.078 0.033
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.040
LIG1 LIG1: DNA ligase 1 0.078 0.066
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.066
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.066
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.078 0.066
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.078 0.066
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.040
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.040
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.078 0.040
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.146
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.241
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.078 0.040
CDK7 CDK7, MO15: Cell division protein kinase 7 0.078 0.241
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.066
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.118
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.078 0.066
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.112
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.129
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.078 0.040
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.040
TIAL1 TIAL1: Nucleolysin TIAR 0.078 0.066
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.096
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.077 0.026
EEF2 EEF2, EF2: Elongation factor 2 0.075 0.063
GIT2 N/A 0.075 0.075
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.025
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.074 0.032
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.074 0.129
PHB2 PHB2, BAP, REA: Prohibitin-2 0.074 0.144
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.074 0.307
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.070 0.026
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.070 0.074
WDR1 N/A 0.070 0.027
PLEK PLEK, P47: Pleckstrin 0.070 0.202
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.070 0.036
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.144
STK16 N/A 0.070 0.0971
KIAA0853 N/A 0.070 0.027
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.070 0.036
API5 N/A 0.070 0.087
UBAP2 N/A 0.070 0.087
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.036
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.027
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.070
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.086
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.067 0.038
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.038
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.067 0.071
SYK SYK: Tyrosine-protein kinase SYK 0.067 0.029
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.066 0.385
HSPD1 0.066 0.276
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.066 145.00
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.066 0.276
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.066 0.129
VCP VCP: Transitional endoplasmic reticulum ATPase 0.066 0.078
QARS QARS: Glutaminyl-tRNA synthetase 0.066 0.078
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.066 0.276
CTPS CTPS: CTP synthase 1 0.066 0.276
CCT8 CCT8: Uncharacterized protein CCT8 0.066 0.276
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.066 0.276
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.066 0.078
TCP1 CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha 0.066 0.144
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.066 0.048
HNRPK N/A 0.066 0.078
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.066 0.276
GPI GPI: Glucose-6-phosphate isomerase 0.066 0.078
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.066 0.144
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.066 145.00
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.063 0.040
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.046
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.063 0.032
PPP1R8 N/A 0.063 0.040
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.040
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.063
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.078
RPS6KB1 N/A 0.063 0.139
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.139
RBM7 0.063 0.040
WBSCR20A N/A 0.063 0.032
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.241
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.063 0.225
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.032
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.063 0.066
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.063 0.032
MYH9 MYH9: Myosin-9 0.063 0.148
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.385
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.066
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.063 0.241
COPA COPA: Coatomer subunit alpha 0.063 0.046
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.032
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.063 0.040
WEE1 WEE1: Wee1-like protein kinase 0.063 0.146
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.063 0.118
LYN LYN: Tyrosine-protein kinase Lyn 0.061 0.029
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.061 0.032
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.061 0.0425
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.057 0.048
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.043
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.069
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.046
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.0554 0.038
SOS1 SOS1: Son of sevenless homolog 1 0.054 0.113
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.054
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.0446
CHUK N/A 0.052 0.052
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.036
TOP2B N/A 0.052 0.036
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.027
TRRAP N/A 0.052 0.070
ARFGAP1 N/A 0.052 0.091
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.307
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.027
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.027
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.070
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.052
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.307
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.051 0.054
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.225
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.052
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.049 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.028
STAT3 0.049 0.025
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.052
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.052
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.049 0.097
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 0.0308
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.049
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.795
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.047 0.098
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.025
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.046 0.114
SAPS3 N/A 0.046 0.046
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.046 0.118
SYMPK SYMPK, SPK: Symplekin 0.046 0.139
MDN1 MDN1, KIAA0301: Midasin 0.046 0.063
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.114
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.146
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.032
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.046 0.032
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.046 0.146
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.225
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.038
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.275
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.046 0.040
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.046 0.114
DOK1 DOK1: Docking protein 1 0.046 0.171
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.038
KLHDC4 N/A 0.046 0.046
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.046 0.032
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.046 0.114
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.046 0.225
GSK3B N/A 0.046 0.046
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.071
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.046 0.032
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0453 0.032
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0453 0.039
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.0446 0.052
HPRT1 HPRT1, HPRT: Hypoxanthine-guanine phosphoribosyltransferase 0.0446 0.025
GTPBP4 GTPBP4, CRFG, NOG1: Nucleolar GTP-binding protein 1 0.0446 0.054
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.0446 0.144
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0446 0.307
TK1 TK1: Thymidine kinase, cytosolic 0.0446 0.129
FUBP1 N/A 0.0446 0.087
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.028
KLC2 KLC2: Kinesin light chain 2 0.044 0.0308
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.148
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.061
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.032
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.027
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.096
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.048
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.032
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.060
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.191
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.080
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.0425 0.032
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.027
MARK2 N/A 0.0425 0.026
FANCG FANCG, XRCC9: Fanconi anemia group G protein 0.042 0.042
EXOC2 N/A 0.041 0.029
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.041 0.038
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.041 0.071
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 0.028
LCP1 LCP1, PLS2: Plastin-2 0.040 0.139
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.040 0.063
CD2AP CD2AP: CD2-associated protein 0.040 0.078
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.040 0.129
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.040 0.129
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.040 0.129
LDHB LDHB: L-lactate dehydrogenase B chain 0.040 0.276
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.040 0.048
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.040 0.276
THOP1 THOP1: Thimet oligopeptidase 0.040 0.078
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.040 0.129
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.040 0.063
RPL8 RPL8: 60S ribosomal protein L8 0.040 0.078
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.040 4.15
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.040 0.063
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.040 0.129
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.040 0.129
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.040 23.90
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.040 0.078
LPXN LPXN, LDLP: Leupaxin 0.040 0.063
XPO1 XPO1, CRM1: Exportin-1 0.040 202.00
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.039 0.026
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.038 0.086
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.043
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.038 0.054
PSMD5 PSMD5, KIAA0072: 26S proteasome non-ATPase regulatory subunit 5 0.038 0.037
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.071
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.275
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.139
STK10 STK10: Uncharacterized protein STK10 0.038 0.054
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.038 0.029
CSTF3 CSTF3: Cleavage stimulation factor 77 kDa subunit 0.038 0.081
SRPR SRPR: Uncharacterized protein SRPR 0.036 0.052
HD HD, IT15: Huntingtin 0.036 0.210
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.036 0.052
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.210
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.036 0.210
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.036 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.036 0.148
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.034 0.026
AXIN1 0.0333 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.0333 0.028
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.033 0.114
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.034
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.048
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.048
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.048
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.039
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.191
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.032 0.275
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.032 0.188
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.032 0.076
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.032 0.146
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.063
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.275
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.032 0.063
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.032 0.038
CASP3 CASP3, CPP32: Caspase-3 precursor 0.032 0.078
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.063
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.027
ACTG1 ACTB: Actin, cytoplasmic 1 0.032 3.97
NRAS NRAS, HRAS1: GTPase NRas precursor 0.032 0.078
FLII FLII, FLIL: Protein flightless-1 homolog 0.032 0.071
PLD1 PLD1: Phospholipase D1 0.032 0.275
PPARBP N/A 0.032 0.063
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.032 0.078
CRKL CRKL: Crk-like protein 0.032 0.146
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.032 0.078
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.032 0.129
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.275
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.032 0.129
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.032 0.063
NFIB N/A 0.031 0.072
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.069
CSDA CSDA, DBPA: DNA-binding protein A 0.029 0.038
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.054
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.029 0.056
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.029 0.038
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.069
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.071
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.056
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.052
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.052
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.075
SYTL4 Endocrine transmitter regulatory protein 0.028 0.044
NF2 NF2, SCH: Merlin 0.028 0.165
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.165
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.047
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
RAB4A N/A 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.052
PHLDB2 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.050
MAPKAPK5 N/A 0.028 0.052
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.047
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.047
DSP DSP: Desmoplakin 0.028 0.04
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
BUB3 N/A 0.027 0.027
C22orf18 N/A 0.027 0.027
SERBP1 N/A 0.027 0.027
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.027 0.111
IPO9 IPO9, IMP9, HSPC273, KIAA1192, RANBP9: Importin-9 0.027 0.140
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.027 0.0425
MPG N/A 0.027 0.052
YWHAQ YWHAQ: 14-3-3 protein theta 0.027 0.087
CIITA CIITA, MHC2TA: MHC class II transactivator 0.027 0.0425
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.275
BMX N/A 0.0263 0.098
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.060
PRKAA1 N/A 0.026 0.048
GRLF1 N/A 0.026 0.152
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.026 0.060
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.026
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.026 0.054
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.047
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.075
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.075
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.148
BCOR N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.075
PRKCB1 N/A 0.025 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.036
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.047
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.075
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
ELMO1 N/A 0.025 0.148
GRK6 N/A 0.025 0.025
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.374
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.036
ADK ADK: Adenosine kinase 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.047
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.044
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.047
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.148
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.036
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.044
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.075
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.036
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.047
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.047
KNTC2 KNTC2, HEC, HEC1: Kinetochore protein Hec1 0.025 0.0479
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.025 0.053
0.347
Total Score 9.17