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Evidence of Interaction Between TP53 and BRCA1

The interaction score between TP53 and BRCA1 is 36.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TP53 and BRCA1 = 0.63

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology N/A N/A
Domains Domains present in TP53 and BRCA1:
Domains in TP53Domains in BRCA1
IPR008967 p53-like transcription factor, DNA-binding
IPR002117 p53 tumor antigen
IPR010991 p53, tetramerisation
IPR011615 P53_DNA_bd.
IPR012346 P53_RUNT_DNA_bd.
IPR001841 Zn-finger, RING
IPR001990 Chromogranin/secretogranin
IPR001357 BRCT
IPR002378 Breast cancer type I susceptibility protein
IPR011364 BRCA1.

The Chi square scores for co-occurrence of domains that are present in TP53 and BRCA1 are listed below.

Domain 1Domain 2Chi Square
IPR002117 p53 tumor antigen IPR001841 Zn-finger, RING 0.704097
IPR010991 p53, tetramerisation IPR001841 Zn-finger, RING 0.704097
IPR011615 P53_DNA_bd. IPR001841 Zn-finger, RING 0.704097
IPR012346 P53_RUNT_DNA_bd. IPR001841 Zn-finger, RING 0.704097
IPR008967 p53-like transcription factor, DNA-binding IPR001841 Zn-finger, RING 0.00157184

The background colour of the table refers to:

  • Blue Domain is only present in TP53
  • Yellow Domain is only present in BRCA1
  • Green Domain is present in both TP53 and BRCA1

 0.083
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: BRCA1

PTMResidueReference
Phosphorylation 308 PubMed, HPRD
Phosphorylation 509 PubMed, HPRD
Phosphorylation 988 PubMed, HPRD
Phosphorylation 1143 PubMed, HPRD
Phosphorylation 1189 PubMed, HPRD
Phosphorylation 1280 PubMed, HPRD
Phosphorylation 1330 PubMed, HPRD
Phosphorylation 1387 PubMed, HPRD
Phosphorylation 1394 PubMed, HPRD
Phosphorylation 1423 PubMed, HPRD
Phosphorylation 1457 PubMed, HPRD
Phosphorylation 1466 PubMed, HPRD
Phosphorylation 1497 PubMed, HPRD
Phosphorylation 1524 PubMed, HPRD
Phosphorylation 1542 PubMed, HPRD
Phosphorylation 1572 PubMed, HPRD
Phosphoserine 1143 PubMed, HPRD
Phosphoserine 1280 PubMed, HPRD
Phosphoserine 1387 PubMed, HPRD
Phosphoserine 1423 PubMed, HPRD
Phosphoserine 1457 PubMed, HPRD
Phosphoserine 1524 PubMed, HPRD
Phosphothreonine 1394 PubMed, HPRD
Proteolytic Cleavage 1155 PubMed, HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: BRCA1

LocalisationReference
Nucleus HPRD
Mitochondrion HPRD
Centrosome HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and BRCA1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andBRCA1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and BRCA1 has 1040 interactors of which there are 806 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for BRCA1-Interactor (?)
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.77 0.070
H2AFX H2AFX, H2AX: Histone H2A.x 4.27 0.515
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 2.54 0.086
HIST1H1E HIST1H1E, H1F4: Histone H1.4 2.08 0.069
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.038
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 1.58 0.086
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 1.58 0.056
HIST1H1B HIST1H1B, H1F5: Histone H1.5 1.26 0.069
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 0.486
HIST1H4A HIST1H4A, H4/A, HIST1H4B, H4/I, H4/G, HIST1H4D, H4/B, H4/J, HIST1H4F, HIST4H4, H 0.902 0.049
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.129
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.070
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.704 0.139
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.763
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.080
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.541 0.101
SP100 N/A 0.525 0.032
MCM3 MCM3: DNA replication licensing factor MCM3 0.515 0.276
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.503 0.090
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.503 0.067
SREBF2 N/A 0.475 0.052
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.385
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.416
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.515
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.210
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.210
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.852
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.416
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.144
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 141.00
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.210
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.425 0.114
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.129
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.188
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.188
CCNB1 Cyclin B1 0.385 0.763
SP3 SP3: Transcription factor Sp3 0.347 0.114
SRF SRF: Serum response factor 0.344 0.0425
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.318 0.114
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.304 0.111
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.304 0.067
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.290 0.0425
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.284 0.114
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.078
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.276 0.078
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.129
POLA2 POLA2: DNA polymerase subunit alpha B 0.276 0.129
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.078
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.276 0.129
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.276 0.461
CENPA CENPA: Histone H3-like centromeric protein A 0.269 0.260
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.260
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.210
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.0425
EP300 N/A 0.254 0.038
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.254 0.265
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.253 0.0446
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.245 0.112
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.241 0.078
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.241 0.129
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.241 0.129
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.260
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.461
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.118
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.233 0.046
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.155
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.155
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.227 0.066
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.216 0.077
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.114
RB1 RB1: Retinoblastoma-associated protein 0.210 0.210
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.260
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.096
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.210
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.086
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.139
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.307
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.188 0.046
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.139
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.188 0.114
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.155
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.114
CXorf9 N/A 0.188 0.080
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.114
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.188 0.086
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.187 0.075
MYB MYB: Myb proto-oncogene protein 0.176 0.155
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.172 0.055
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.172 0.152
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.162 0.202
TP73 TP73, P73: Tumor protein p73 0.156 0.077
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.156 0.055
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.096
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.155 0.152
ZNF267 ZNF267: Zinc finger protein 267 0.155 0.096
ERF ERF: ETS domain-containing transcription factor ERF 0.155 0.077
XRCC1 XRCC1: DNA-repair protein XRCC1 0.155 0.251
MITF MITF: Microphthalmia-associated transcription factor 0.152 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.152 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.152 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.028
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 0.148 0.0735
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.146 0.139
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.146 0.078
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.146 0.114
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.146 0.078
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.146 0.385
ABCF1 N/A 0.144 0.070
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.087
MKI67 MKI67: Antigen KI-67 0.144 0.430
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.144 0.052
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.087
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.087
ESPL1 N/A 0.144 0.144
PTMA N/A 0.144 0.070
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.141 0.066
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.141 0.111
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.141 0.040
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.141 0.040
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.141 0.040
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.139 0.127
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.139 0.188
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.054
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.139 0.114
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.071
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.086
COPE COPE: Coatomer subunit epsilon 0.139 0.054
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.139 0.029
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.233
RELA RELA, NFKB3: Transcription factor p65 0.139 0.077
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.054
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.139 0.086
CDC23 CDC23: Cell division cycle protein 23 homolog 0.137 0.112
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.137 0.101
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.137 0.028
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.137 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.132 0.852
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.132 0.087
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.096
CDK4 CDK4: Cell division protein kinase 4 0.129 0.144
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.129 0.070
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.146
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.233
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.129 0.078
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.129 0.129
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.129 0.078
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.129 0.078
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.763
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.129 0.078
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.210
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.063
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.129 0.075
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.129 0.233
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.078
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.233
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.078
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 0.461
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.144
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.129 0.078
NUP153 N/A 0.129 0.087
SSB SSB: Lupus La protein 0.129 0.078
KIF11 N/A 0.129 0.276
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.078
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.276
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.233
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.430
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.385
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.127 0.191
ZNF335 ZNF335: Zinc finger protein 335 0.127 0.069
ZFX ZFX: Zinc finger X-chromosomal protein 0.127 0.096
HIVEP1 N/A 0.127 0.096
SALL1 SALL1, SAL1: Sal-like protein 1 0.125 0.044
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.227
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.118 0.063
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.118 0.139
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.118 0.385
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.114 0.069
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.071
ETS1 ETS1, EWSR2: Protein C-ets-1 0.114 0.056
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.071
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.071
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.114 0.048
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.054
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.114 0.127
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.136
CCNH CCNH: Cyclin-H 0.114 0.086
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.114 0.096
MTF1 MTF1: Metal regulatory transcription factor 1 0.114 0.096
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.114 0.056
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.114 0.069
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.054
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.114 0.136
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 0.086
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.114 0.0425
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.114
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.112 0.036
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.112 0.036
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.111 0.056
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.111 0.124
HSP90AA1 Hsp89-alpha-delta-N 0.111 0.032
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.041
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.102 0.035
GTF2F2 N/A 0.0971 0.127
STAT2 STAT2: Signal transducer and activator of transcription 2 0.096 0.096
NFATC1 N/A 0.096 0.096
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.096 0.210
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.069
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.096 0.039
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.093 0.032
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.090 0.044
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.087 0.052
GNB2L1 Lung cancer oncogene 7 0.087 0.155
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.0425
NCOA3 N/A 0.087 0.032
SET SET: Protein SET 0.087 0.087
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.070
TCOF1 N/A 0.087 0.087
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.052
IFI16 N/A 0.087 0.0425
KIF23 N/A 0.087 0.087
DNMT1 DNMT1, AIM, DNMT: DNA 0.087 0.087
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.087 0.251
TGIF2 TGIF2: Homeobox protein TGIF2 0.087 0.155
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.087
UNG N/A 0.087 0.078
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.087 0.0425
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.087 0.139
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.087 0.114
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.087 0.046
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.087 0.069
SOX4 SOX4: Transcription factor SOX-4 0.086 0.032
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.086 0.049
BRPF1 BRPF1, BR140: Peregrin 0.086 0.077
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.086 0.069
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.086
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.086 0.086
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.086 0.111
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.069
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.086 0.152
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.086 0.048
ATM ATM: Serine-protein kinase ATM 0.086 0.111
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.084 0.027
PPEF1 N/A 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.083
MAPK15 N/A 0.083 0.028
C20orf18 N/A 0.083 0.165
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.083
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.083
UHRF1 0.083 0.083
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.083
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.047
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.083
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.083
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.083
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.0818 0.054
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.0818 0.067
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.0818 0.036
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.067
H1FX H1FX: Histone H1x 0.080 0.077
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.078 0.046
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.139
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.046
FNBP1 N/A 0.078 0.029
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.078 0.046
CDK2 CDK2: Cell division protein kinase 2 0.078 0.144
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.078 0.233
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.046
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.078
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.063
LIG1 LIG1: DNA ligase 1 0.078 0.129
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.078
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.078
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.078 0.070
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.078 0.233
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.078 0.063
NOL1 N/A 0.078 0.078
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.063
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.046
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.078 0.087
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.129
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.046
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.078 0.046
CDK7 CDK7, MO15: Cell division protein kinase 7 0.078 0.046
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.260
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.251
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.078 0.087
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.063
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.139
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.078 0.052
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.063
TIAL1 TIAL1: Nucleolysin TIAR 0.078 0.063
ETS2 ETS2: Protein C-ets-2 0.077 0.062
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.191
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.086
ERG ERG: Transcriptional regulator ERG 0.077 0.127
MDM4 MDM4, MDMX: Mdm4 protein 0.077 0.062
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.077 0.056
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.077 0.191
EEF2 EEF2, EF2: Elongation factor 2 0.075 0.067
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.083
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.083
BRD4 N/A 0.075 0.025
SOX8 SOX8: Transcription factor SOX-8 0.075 0.028
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.075 0.028
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.075
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.083
GIT2 N/A 0.075 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.075
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.148
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.075 0.025
CCNT2 CCNT2: Cyclin-T2 0.075 0.075
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.075
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.075
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.075
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.075 0.083
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.075 0.083
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.083
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.075 0.075
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.075 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.075 0.075
RNF20 0.075 0.075
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.074 0.032
PHB2 PHB2, BAP, REA: Prohibitin-2 0.074 0.036
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.074 0.0446
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.071 0.069
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.071 0.025
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.070 0.0425
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.070 0.070
WDR1 N/A 0.070 0.077
PLEK PLEK, P47: Pleckstrin 0.070 0.032
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.070 0.087
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.144
STK16 N/A 0.070 0.032
KIAA0853 N/A 0.070 0.052
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.070 0.052
API5 N/A 0.070 0.052
UBAP2 N/A 0.070 0.087
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.0425
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.0425
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.0425
ZNF551 N/A 0.069 0.114
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.069 0.077
LIG4 LIG4: DNA ligase 4 0.069 0.171
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.069 0.077
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.069 0.049
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.069 0.127
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.069 0.123
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.067
SYK SYK: Tyrosine-protein kinase SYK 0.067 0.046
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.066 0.032
HSPD1 0.066 0.040
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.066 0.040
VCP VCP: Transitional endoplasmic reticulum ATPase 0.066 0.067
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.066 0.066
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.066 0.040
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.066 0.032
CTPS CTPS: CTP synthase 1 0.066 0.066
CCT8 CCT8: Uncharacterized protein CCT8 0.066 0.066
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.066 0.066
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.066 0.202
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.066 0.040
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.066 0.040
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.066 0.040
MTHFD1 MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic 0.066 0.040
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.063 0.155
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.038
CORO1C CORO1C, CRNN4: Coronin-1C 0.063 0.114
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.063 0.032
PPP1R8 N/A 0.063 0.139
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.139
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.038
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.225
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.046
RPS6KB1 N/A 0.063 0.038
SEC31L1 N/A 0.063 0.086
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.054
RBM7 0.063 0.046
WBSCR20A N/A 0.063 0.046
PHF10 N/A 0.063 0.139
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.078
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.046
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.063 0.063
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.029
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.063 0.063
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.118
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.063 0.038
COPB2 COPB2: Coatomer subunit beta' 0.063 0.114
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.188
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.063 0.144
Nle NLE1, HUSSY-07: Notchless protein homolog 1 0.063 0.027
COPA COPA: Coatomer subunit alpha 0.063 0.086
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.114
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.063 0.276
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.063 0.046
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.155
WEE1 WEE1: Wee1-like protein kinase 0.063 0.087
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.063 0.046
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.152
SH3BP3 0.062 0.062
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.096
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.062 0.077
RNF7 RNF7, RBX2, ROC2, SAG: RING-box protein 2 0.061 0.030
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.060 0.049
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.077
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.073
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.056 0.057
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.136
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.056 0.098
SP1 SP1, TSFP1: Transcription factor Sp1 0.056 0.056
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.111
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.056 0.086
ETV1 ETV1, ER81: ETS translocation variant 1 0.056 0.055
STAT4 STAT4: Signal transducer and activator of transcription 4 0.055 0.049
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.055 0.055
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.055 0.026
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.054 0.126
SOS1 SOS1: Son of sevenless homolog 1 0.054 0.086
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.054 0.032
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.083
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.083
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.052
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.080
CHUK N/A 0.052 0.052
AFF1 N/A 0.052 0.032
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.155
TOP2B N/A 0.052 0.052
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.0425
EMD EMD, EDMD, STA: Emerin 0.052 0.032
TRRAP N/A 0.052 0.0425
ARFGAP1 N/A 0.052 0.052
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.0425
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.032
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.127
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.052
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.032
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.307
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.0425
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.041
RNF11 RNF11, CGI-123: RING finger protein 11 0.050 0.050
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.050 0.044
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.049 0.056
SF3A3 SF3A3, SAP61: Splicing factor 3A subunit 3 0.049 0.049
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.109
STAT3 0.049 0.044
NASP NASP: Nuclear autoantigenic sperm protein 0.049 0.04
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.049 0.055
ELK1 ELK1: ETS domain-containing protein Elk-1 0.049 0.069
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.048
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.049 0.049
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.048 0.032
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.048 0.026
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.075
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.047 0.165
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.047 0.165
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.047 0.075
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.047 0.075
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.028
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.046 0.060
SAPS3 N/A 0.046 0.038
SYMPK SYMPK, SPK: Symplekin 0.046 0.071
CUL5 CUL5, VACM1: Cullin-5 0.046 0.225
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.046
MDN1 MDN1, KIAA0301: Midasin 0.046 0.139
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.029
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.078
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.070
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.046 0.070
FZR1 N/A 0.046 0.029
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.046 0.144
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.046 0.069
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.046 0.069
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.038
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.251
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.046 0.046
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.046 0.069
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.046 0.038
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.046 0.032
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.038
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.029
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.046 0.139
DIAPH1 Diaphanous 1 0.046 0.038
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.069
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.046 0.029
DOK1 DOK1: Docking protein 1 0.046 0.032
KLHDC4 N/A 0.046 0.0425
WDR79 N/A 0.046 0.046
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.046 0.0425
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.046 0.032
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.046 0.038
CRSP2 MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol 0.046 0.046
CUL4B N/A 0.046 0.0425
GSK3B N/A 0.046 0.029
ARMET ARMET, ARP: Protein ARMET precursor 0.046 0.038
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.029
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.046 0.0453
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0453 0.075
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.0446 0.206
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0446 0.0446
TK1 TK1: Thymidine kinase, cytosolic 0.0446 0.066
FUBP1 N/A 0.0446 0.027
EGR1 EGR1, ZNF225: Early growth response protein 1 0.044 0.055
KLC2 KLC2: Kinesin light chain 2 0.044 0.044
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.049
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.043 0.049
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.043 0.069
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.0425 0.191
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.0425
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.032
XRCC4 N/A 0.0425 0.0425
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.026
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.155
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.127
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.026
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.096
SMARCC2 N/A 0.0425 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.062
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.026
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.026
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.032
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.0425 0.114
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.0425
RGS14 N/A 0.0425 0.026
COIL COIL, CLN80: Coilin 0.0425 0.0425
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.042 0.0255
FANCG FANCG, XRCC9: Fanconi anemia group G protein 0.042 0.0278
EXOC2 N/A 0.041 0.033
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.041 0.113
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.041 0.027
CD2AP CD2AP: CD2-associated protein 0.040 0.032
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.040 0.032
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.040 0.066
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.040 0.111
LDHB LDHB: L-lactate dehydrogenase B chain 0.040 0.032
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.040 0.066
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.040 0.032
THOP1 THOP1: Thimet oligopeptidase 0.040 0.032
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.040 0.032
RPL8 RPL8: 60S ribosomal protein L8 0.040 0.027
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.040 0.227
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.040 0.032
XPO1 XPO1, CRM1: Exportin-1 0.040 0.112
POLR2A POLR2A: Uncharacterized protein POLR2A 0.038 0.114
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.029
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.038 0.029
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.038 0.046
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.029
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.029
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.038
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.038
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.071
MAFG MAFG: Transcription factor MafG 0.038 0.251
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.038 0.086
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.038 0.029
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.038 0.0425
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.038 0.029
CCNA2 CCNA2, CCN1, CCNA: Cyclin-A2 0.038 0.123
PES1 PES1: Pescadillo homolog 1 0.038 0.074
SAFB2 SAFB2, KIAA0138: Scaffold attachment factor B2 0.036 0.033
E2F5 E2F5: Transcription factor E2F5 0.036 0.044
HD HD, IT15: Huntingtin 0.036 0.091
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.101
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.036 0.036
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 0.098
H1F0 H1F0, H1FV: Histone H1.0 0.035 0.077
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.035 0.062
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.034 0.056
FOXL2 FOXL2: Forkhead box protein L2 0.034 0.056
SCML2 SCML2: Sex comb on midleg-like protein 2 0.034 0.026
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.034
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.033 0.0263
MAGED2 N/A 0.033 0.029
BACH1 BACH1: Transcription regulator protein BACH1 0.032 0.123
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.152
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.032 0.026
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.026
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.077
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.032
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.032 0.026
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.026
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.032
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.032 0.041
FRG1 FRG1: Protein FRG1 0.032 0.032
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.148
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.032 0.067
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.032 0.0818
CASP3 CASP3, CPP32: Caspase-3 precursor 0.032 0.091
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.032 0.032
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.067
PPARBP N/A 0.032 0.027
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.032 0.032
CRKL CRKL: Crk-like protein 0.032 0.032
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.032 0.027
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.032 0.137
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.054
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.032 0.181
CUL2 CUL2: Cullin-2 0.032 0.093
NFIB N/A 0.031 0.056
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.031 0.034
RFX1 RFX1: MHC class II regulatory factor RFX1 0.0308 0.056
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.0308 0.049
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.030 0.030
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.030 0.030
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.030
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.029 0.038
METTL1 METTL1, C12orf1: tRNA 0.029 0.038
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.029 0.136
JUND JUND: Transcription factor jun-D 0.029 0.111
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.029 0.086
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.069
CSDA CSDA, DBPA: DNA-binding protein A 0.029 0.038
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.029 0.097
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.032
SMCX JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C 0.029 0.069
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.029 0.114
RUNX1 N/A 0.029 0.038
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.029 0.139
TOP3A TOP3A, TOP3: DNA topoisomerase 3-alpha 0.029 0.038
JUNB JUNB: Transcription factor jun-B 0.029 0.111
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.029
POLB POLB: DNA polymerase beta 0.029 0.032
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.029 0.029
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
BID BID: BH3-interacting domain death agonist 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.083
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.028
ZNF265 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.052
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.025
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.028 0.075
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.083
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
C13orf8 N/A 0.028 0.028
DUSP15 N/A 0.028 0.028
RAB4A N/A 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
IRF7 N/A 0.028 0.028
WDR54 N/A 0.028 0.083
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.083
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
KIF1B N/A 0.028 0.028
HDAC8 N/A 0.028 0.083
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
NES N/A 0.028 0.028
SNRPB N/A 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.025
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.028 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.025
CORO6 N/A 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.025
FLJ23436 N/A 0.028 0.025
DSP DSP: Desmoplakin 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.083
CABLES1 N/A 0.028 0.028
HDAC7A N/A 0.028 0.047
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
HIST2H2BE HIST2H2BE, H2BFQ: Histone H2B type 2-E 0.028 0.044
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.027 0.033
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.027 0.027
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.027 0.081
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.0425
PRKAA1 N/A 0.026 0.026
GRLF1 N/A 0.026 0.026
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.032
NUP214 N/A 0.026 0.077
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.026 0.026
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.123
KRT18 KRT18: Uncharacterized protein KRT18 0.026 0.055
IFIH1 IFIH1, MDA5, RH116: Interferon-induced helicase C domain-containing protein 1 0.0255 0.044
PARP4 PARP4, ADPRTL1, KIAA0177, PARPL: Poly [ADP-ribose] polymerase 4 0.0255 0.050
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.028
SON 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.075
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.028
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.028
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.025
BCOR N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.075
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.083
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.075
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.075
KCTD1 0.025 0.028
MAPK8IP3 N/A 0.025 0.025
MAX MAX: Protein max 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.047
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.083
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.083
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
PRKCB1 N/A 0.025 0.025
CREB1 CREB1: cAMP response element-binding protein 0.025 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.083
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
NUP98 N/A 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
SEC13L1 N/A 0.025 0.025
NIPBL N/A 0.025 0.047
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.075
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
ATXN2L N/A 0.025 0.025
ELMO1 N/A 0.025 0.047
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.028
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.075
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
GRK6 N/A 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.075
C20orf77 N/A 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.028
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.028
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.028
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
HTATIP N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.028
DIDO1 N/A 0.025 0.083
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.148
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
TCEA1 N/A 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.075
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
KNTC2 KNTC2, HEC, HEC1: Kinetochore protein Hec1 0.025 0.0479
NOLC1 NOLC1, KIAA0035: Nucleolar phosphoprotein p130 0.025 0.025
0.347
Total Score 36.00