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Evidence of Interaction Between TP53 and STAT1

The interaction score between TP53 and STAT1 is 17.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismTP53 OrthologueSTAT1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00215713 0.16 IPI00030783 0.067
human IPI00215713 0.16 IPI00103415 0.067

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in TP53 and STAT1:
Domains in TP53Domains in STAT1
IPR008967 p53-like transcription factor, DNA-binding
IPR002117 p53 tumor antigen
IPR010991 p53, tetramerisation
IPR011615 P53_DNA_bd.
IPR012346 P53_RUNT_DNA_bd.
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in TP53 and STAT1 are listed below.

Domain 1Domain 2Chi Square
IPR002117 p53 tumor antigen IPR000980 SH2 motif 4.72854
IPR010991 p53, tetramerisation IPR000980 SH2 motif 4.72854
IPR011615 P53_DNA_bd. IPR000980 SH2 motif 4.72854
IPR012346 P53_RUNT_DNA_bd. IPR000980 SH2 motif 4.72854
IPR008967 p53-like transcription factor, DNA-binding IPR000980 SH2 motif 0.942535

The background colour of the table refers to:

  • Blue Domain is only present in TP53
  • Yellow Domain is only present in STAT1
  • Green Domain is present in both TP53 and STAT1

 0.209
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: STAT1

PTMResidueReference
Dephosphorylation 701 PubMed, HPRD
Dephosphorylation 727 PubMed, HPRD
Methylation 31 PubMed, HPRD
Phosphorylation 701 PubMed, HPRD
Phosphorylation 727 PubMed, HPRD
Phosphoserine 727 HPRD
Phosphotyrosine 701 PubMed, HPRD
Sumoylation 703 PubMed, HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: STAT1

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and STAT1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andSTAT1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and STAT1 has 1786 interactors of which there are 897 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for STAT1-Interactor (?)
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.77 0.052
H2AFX H2AFX, H2AX: Histone H2A.x 4.27 0.025
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 2.54 0.025
HIST1H1E HIST1H1E, H1F4: Histone H1.4 2.08 0.075
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.047
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 1.58 0.025
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 1.58 0.025
HIST1H1B HIST1H1B, H1F5: Histone H1.5 1.26 0.187
PGR PGR, NR3C3: Progesterone receptor 1.00 0.052
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 1.37
HIST1H4A HIST1H4A, H4/A, HIST1H4B, H4/I, H4/G, HIST1H4D, H4/B, H4/J, HIST1H4F, HIST4H4, H 0.902 0.025
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.902 0.047
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.025
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.187
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.704 0.075
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.025
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.083
SP100 N/A 0.525 0.028
MCM3 MCM3: DNA replication licensing factor MCM3 0.515 0.047
SREBF2 N/A 0.475 0.028
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.025
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.052
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.083
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.028
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.028
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.028
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.083
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.028
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 0.047
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.028
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.425 0.156
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.025
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.025
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.025
CCNB1 Cyclin B1 0.385 0.025
SP3 SP3: Transcription factor Sp3 0.347 0.025
SRF SRF: Serum response factor 0.344 0.028
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.318 0.075
SNRPA SNRPA: U1 small nuclear ribonucleoprotein A 0.307 0.025
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.304 0.098
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.290 0.028
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.284 0.075
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.025
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.276 0.025
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.025
POLA2 POLA2: DNA polymerase subunit alpha B 0.276 0.025
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.025
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.276 0.025
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.276 0.075
CENPA CENPA: Histone H3-like centromeric protein A 0.269 0.028
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.083
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.028
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.260 0.075
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.028
EP300 N/A 0.254 0.137
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.254 0.028
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.241 0.047
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.241 0.047
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.241 0.047
POLR2H POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3 0.241 0.047
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.028
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.047
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.025
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.233 0.148
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.025
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.083
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.216 0.025
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.216 0.028
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.075
RB1 RB1: Retinoblastoma-associated protein 0.210 0.028
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.083
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.083
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.028
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.208 0.025
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.025
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.025
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.028
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.188 0.047
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.025
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.188 0.075
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.025
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.025
CXorf9 N/A 0.188 0.148
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.025
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.188 0.025
MYB MYB: Myb proto-oncogene protein 0.176 0.028
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.172 0.075
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.172 0.075
TP73 TP73, P73: Tumor protein p73 0.156 0.165
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.156 0.165
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.028
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.155 0.165
ZNF267 ZNF267: Zinc finger protein 267 0.155 0.028
ERF ERF: ETS domain-containing transcription factor ERF 0.155 0.083
XRCC1 XRCC1: DNA-repair protein XRCC1 0.155 0.052
MITF MITF: Microphthalmia-associated transcription factor 0.152 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.152 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.152 0.028
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.152
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.146 0.075
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.146 0.047
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.146 0.025
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.146 0.047
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.146 0.075
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.145 0.044
ABCF1 N/A 0.144 0.028
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.028
MKI67 MKI67: Antigen KI-67 0.144 0.028
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.144 0.165
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.028
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.028
ESPL1 N/A 0.144 0.028
PTMA N/A 0.144 0.028
SAT SAT1, SAT: Diamine acetyltransferase 1 0.140 0.028
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.140 0.025
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.139 0.148
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.139 0.025
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.075
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.139 0.025
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.025
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.025
COPE COPE: Coatomer subunit epsilon 0.139 0.025
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.139 0.075
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.025
RELA RELA, NFKB3: Transcription factor p65 0.139 0.075
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.025
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.139 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.137 0.028
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.137 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.156
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.137
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.132 0.083
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.132 0.083
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.165
CDK4 CDK4: Cell division protein kinase 4 0.129 0.148
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.129 0.028
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.148
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.025
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.129 0.025
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.129 0.025
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.129 0.025
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.129 0.025
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.025
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.129 0.025
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.083
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.148
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.129 0.025
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.129 0.025
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.025
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.025
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.025
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 0.025
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 0.129 0.025
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.028
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.129 0.025
NUP153 N/A 0.129 0.028
SSB SSB: Lupus La protein 0.129 0.025
KIF11 N/A 0.129 0.025
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.025
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.148
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.025
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.025
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.025
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.127 0.052
ZNF335 ZNF335: Zinc finger protein 335 0.127 0.025
ZFX ZFX: Zinc finger X-chromosomal protein 0.127 0.028
HIVEP1 N/A 0.127 0.028
SALL1 SALL1, SAL1: Sal-like protein 1 0.125 0.025
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.044
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.118 0.047
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.118 0.148
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.118 0.075
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.114 0.025
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.025
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.114 0.148
ETS1 ETS1, EWSR2: Protein C-ets-1 0.114 0.075
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.025
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.075
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.114 0.028
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.114 0.148
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.025
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.114 0.028
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.148
CCNH CCNH: Cyclin-H 0.114 0.025
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.114 0.025
MTF1 MTF1: Metal regulatory transcription factor 1 0.114 0.025
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.114 0.148
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.114 0.025
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.075
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.114 0.025
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.114 0.075
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 199.00
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.114 0.148
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.025
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.112 0.044
CSK CSK: Tyrosine-protein kinase CSK 0.112 0.878
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.112 0.980
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.111 0.025
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.111 0.980
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 131.00
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.102 0.075
TFAP2C TFAP2C: Transcription factor AP-2 gamma 0.102 0.025
GTF2F2 N/A 0.0971 0.083
STAT2 STAT2: Signal transducer and activator of transcription 2 0.096 0.165
NFATC1 N/A 0.096 0.083
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.096 0.028
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.025
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.096 0.165
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.093 0.030
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.090 0.025
TCF7L2 N/A 0.090 0.028
TFAP2B TFAP2B: Transcription factor AP-2 beta 0.090 0.028
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.087 0.165
GNB2L1 Lung cancer oncogene 7 0.087 0.028
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.028
NCOA3 N/A 0.087 0.028
SET SET: Protein SET 0.087 0.028
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.028
TCOF1 N/A 0.087 0.028
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.028
IFI16 N/A 0.087 0.028
KIF23 N/A 0.087 0.028
DNMT1 DNMT1, AIM, DNMT: DNA 0.087 0.028
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.087 0.083
TGIF2 TGIF2: Homeobox protein TGIF2 0.087 0.028
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.028
UNG N/A 0.087 0.025
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.087 0.028
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.087 0.025
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.087 0.075
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.087 0.047
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.087 0.025
SOX4 SOX4: Transcription factor SOX-4 0.086 0.028
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.086 0.025
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.086 0.075
BRPF1 BRPF1, BR140: Peregrin 0.086 0.075
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.148
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.086 0.075
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.025
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.086 0.025
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.086 0.025
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.025
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.086 0.052
CREBBP CREBBP, CBP: CREB-binding protein 0.086 35.90
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.086 0.028
ATM ATM: Serine-protein kinase ATM 0.086 0.148
GHR GHR: Growth hormone receptor precursor 0.085 0.0688
PPEF1 N/A 0.083 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.028
MAPK15 N/A 0.083 0.165
C20orf18 N/A 0.083 0.028
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.083
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.028
UHRF1 0.083 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.148
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.081 0.148
HIF3A N/A 0.081 0.025
H1FX H1FX: Histone H1x 0.080 0.083
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.078 0.025
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.025
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.025
FNBP1 N/A 0.078 0.148
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.078 0.025
CDK2 CDK2: Cell division protein kinase 2 0.078 0.148
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.078 0.025
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.025
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.025
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 0.078 0.025
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.025
LIG1 LIG1: DNA ligase 1 0.078 0.025
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.025
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.025
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.078 0.028
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.078 0.148
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.078 0.025
NOL1 N/A 0.078 0.025
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.025
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.025
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.078 0.028
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.148
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.148
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.078 0.025
CDK7 CDK7, MO15: Cell division protein kinase 7 0.078 0.148
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.028
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.148
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.078 0.025
U2AF1 U2AF1, U2AF35, U2AFBP: Splicing factor U2AF 35 kDa subunit 0.078 0.025
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.148
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.025
RBM28 RBM28: RNA-binding protein 28 0.078 0.025
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.078 0.028
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.025
TIAL1 TIAL1: Nucleolysin TIAR 0.078 0.025
ETS2 ETS2: Protein C-ets-2 0.077 0.165
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.165
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.025
ERG ERG: Transcriptional regulator ERG 0.077 0.083
MDM4 MDM4, MDMX: Mdm4 protein 0.077 0.028
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.077 0.025
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.077 0.028
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.077 0.028
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.076 0.062
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.025
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.075
BRD4 N/A 0.075 0.075
SOX8 SOX8: Transcription factor SOX-8 0.075 0.028
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.075 0.148
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.025
GIT2 N/A 0.075 0.047
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.047
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.075 0.025
CCNT2 CCNT2: Cyclin-T2 0.075 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.148
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.075 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.075 0.028
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.028
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.075 0.050
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.148
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.075 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.075 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.075 0.025
RNF20 0.075 0.025
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.074 0.980
PHB2 PHB2, BAP, REA: Prohibitin-2 0.074 0.04
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.074 0.04
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.071 0.075
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.071 0.0688
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.070 0.165
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.070 0.028
WDR1 N/A 0.070 0.028
PLEK PLEK, P47: Pleckstrin 0.070 0.165
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.070 0.028
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.028
STK16 N/A 0.070 0.165
KIAA0853 N/A 0.070 0.028
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.070 0.028
TPM4 TPM4: Tropomyosin alpha-4 chain 0.070 0.083
API5 N/A 0.070 0.028
UBAP2 N/A 0.070 0.028
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.028
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.028
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.028
ZNF551 N/A 0.069 0.025
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.069 0.025
LIG4 LIG4: DNA ligase 4 0.069 0.047
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.069 0.075
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.069 0.050
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.047
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.069 0.025
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.069 0.148
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.069 0.025
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.069 0.025
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.069 0.148
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.069 0.075
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.067 0.044
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 131.00
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.067 0.098
SYK SYK: Tyrosine-protein kinase SYK 0.067 0.980
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.066 0.098
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.066 0.044
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.066 0.044
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.063 0.028
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.025
CORO1C CORO1C, CRNN4: Coronin-1C 0.063 0.025
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.063 0.025
PPP1R8 N/A 0.063 0.025
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.025
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.025
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.075
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.025
RPS6KB1 N/A 0.063 0.148
SEC31L1 N/A 0.063 0.025
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.025
RBM7 0.063 0.025
WBSCR20A N/A 0.063 0.025
PHF10 N/A 0.063 0.025
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.148
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.063 0.148
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.148
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.063 0.025
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.025
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.063 0.025
MYH9 MYH9: Myosin-9 0.063 0.148
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.025
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.063 0.025
COPB2 COPB2: Coatomer subunit beta' 0.063 0.025
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.075
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.063 0.165
Nle NLE1, HUSSY-07: Notchless protein homolog 1 0.063 0.025
COPA COPA: Coatomer subunit alpha 0.063 0.025
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.025
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.063 0.025
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.063 0.025
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.025
WEE1 WEE1: Wee1-like protein kinase 0.063 0.165
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.063 0.148
CRLF3 N/A 0.063 0.0688
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.052
SH3BP3 0.062 0.028
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.083
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.062 0.028
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.062 29.60
LYN LYN: Tyrosine-protein kinase Lyn 0.061 0.878
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.061 0.980
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.061 0.980
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.060 0.075
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.083
S100B S100B: Protein S100-B 0.058 0.049
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.057 0.049
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.098
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.057 0.0688
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.148
PCAF PCAF: Histone acetyltransferase PCAF 0.056 0.075
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.056 0.075
SP1 SP1, TSFP1: Transcription factor Sp1 0.056 0.025
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.148
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.056 0.148
ETV1 ETV1, ER81: ETS translocation variant 1 0.056 0.083
STAT4 STAT4: Signal transducer and activator of transcription 4 0.055 22.50
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.055 0.165
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.055 0.083
HCC-1 HCC1, HSPC316: Nuclear protein Hcc-1 0.055 0.083
SOS1 SOS1: Son of sevenless homolog 1 0.054 0.148
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.054 0.052
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.029
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.083
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.083
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.028
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.028
CHUK N/A 0.052 0.028
AFF1 N/A 0.052 0.028
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.028
TOP2B N/A 0.052 0.028
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.028
EMD EMD, EDMD, STA: Emerin 0.052 0.028
TRRAP N/A 0.052 0.028
ARFGAP1 N/A 0.052 0.052
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.165
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.028
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.028
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.028
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.028
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.028
JAK1 0.051 0.980
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.051 0.098
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.051 422.00
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.098
RNF11 RNF11, CGI-123: RING finger protein 11 0.050 0.025
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.050 0.025
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.049 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.109
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.049 0.109
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.049
STAT3 0.049 14.80
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.109
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.049 0.025
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.049 0.148
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 71.20
ELK1 ELK1: ETS domain-containing protein Elk-1 0.049 0.075
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.028
SOX11 SOX11: Transcription factor SOX-11 0.049 0.025
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.049 0.025
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.048 0.052
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.048 0.165
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.048 0.052
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.075
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.047 0.148
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.047 0.025
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.047 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.047 0.075
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.047
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.046 0.165
SAPS3 N/A 0.046 0.025
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.046 0.148
SYMPK SYMPK, SPK: Symplekin 0.046 0.025
CUL5 CUL5, VACM1: Cullin-5 0.046 0.025
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.025
MDN1 MDN1, KIAA0301: Midasin 0.046 0.025
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.148
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.148
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.165
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.046 0.025
FZR1 N/A 0.046 0.025
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.046 0.165
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.046 0.025
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.046 0.025
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.148
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.028
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.046 0.025
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.046 0.025
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.046 0.025
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.046 0.028
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.148
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.047
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.046 0.148
DIAPH1 Diaphanous 1 0.046 0.025
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.025
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.046 0.148
DOK1 DOK1: Docking protein 1 0.046 0.148
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.025
KLHDC4 N/A 0.046 0.028
WDR79 N/A 0.046 0.025
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.046 0.025
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.046 0.028
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.046 0.148
CRSP2 MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol 0.046 0.025
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.046 0.148
CUL4B N/A 0.046 0.028
GSK3B N/A 0.046 0.025
ARMET ARMET, ARP: Protein ARMET precursor 0.046 0.025
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.148
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.0462 21.10
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.046 0.049
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0453 0.049
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.0446 0.109
FUBP1 N/A 0.0446 0.049
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.148
EGR1 EGR1, ZNF225: Early growth response protein 1 0.044 0.025
KLC2 KLC2: Kinesin light chain 2 0.044 0.025
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.044 0.165
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.098
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.044
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.043 0.025
VDR VDR, NR1I1: Vitamin D3 receptor 0.043 0.047
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.043 0.075
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.0425 0.028
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.165
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.028
XRCC4 N/A 0.0425 0.028
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.028
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.028
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.0425 0.028
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.165
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.165
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.028
SMARCC2 N/A 0.0425 0.028
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.028
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.165
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.165
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.165
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.0425 0.148
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.028
RGS14 N/A 0.0425 0.028
MARK2 N/A 0.0425 0.028
COIL COIL, CLN80: Coilin 0.0425 0.028
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.041 0.878
EXOC2 N/A 0.041 0.044
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.04 0.980
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 0.980
LCP1 LCP1, PLS2: Plastin-2 0.040 0.098
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.040 0.044
CD2AP CD2AP: CD2-associated protein 0.040 0.098
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.040 0.098
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.040 0.044
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.040 0.044
HRB2 KRR1, HRB2: KRR1 small subunit processome component homolog 0.040 0.044
LPXN LPXN, LDLP: Leupaxin 0.040 0.044
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.039 1.30
PPARG CREB3L2-PPARgamma 0.039 0.047
SORL1 SORL1: Sortilin-related receptor precursor 0.039 0.0688
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.039 0.0688
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.038 0.148
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.148
POLR2A POLR2A: Uncharacterized protein POLR2A 0.038 0.025
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.038 0.148
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.148
PSMD5 PSMD5, KIAA0072: 26S proteasome non-ATPase regulatory subunit 5 0.038 0.028
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.038 0.025
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.038 0.025
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.025
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.038 0.025
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.025
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.148
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.148
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.025
STK10 STK10: Uncharacterized protein STK10 0.038 0.148
MAFG MAFG: Transcription factor MafG 0.038 0.075
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.038 0.025
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.075
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.038 0.025
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.038 0.148
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.038 0.028
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.038 0.025
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.037 0.980
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.037 0.878
S100A3 S100A3, S100E: Protein S100-A3 0.037 0.049
LIMS1 N/A 0.036 0.049
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.036 0.109
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.036 0.109
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.036 0.878
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 0.878
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.036 0.980
H1F0 H1F0, H1FV: Histone H1.0 0.035 0.075
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.035 0.075
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.034 0.028
FOXL2 FOXL2: Forkhead box protein L2 0.034 0.075
SCML2 SCML2: Sex comb on midleg-like protein 2 0.034 0.165
FN1 N/A 0.034 0.0688
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.034 0.0688
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.034 0.0688
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.034 0.0688
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.034 0.540
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.034
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.034 0.0688
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.034 0.0688
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.034 0.0688
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.034 0.0688
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.034 0.0688
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.034 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.034 0.0688
AXIN1 0.0333 0.049
YWHAG YWHAG: 14-3-3 protein gamma 0.0333 0.0333
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.033 0.878
HCK N/A 0.033 0.878
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.033 422.00
MAGED2 N/A 0.033 0.044
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.049
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.032 0.980
BACH1 BACH1: Transcription regulator protein BACH1 0.032 0.083
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.028
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.165
ID2 ID2: DNA-binding protein inhibitor ID-2 0.032 0.028
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.032 0.028
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.165
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.165
VIM VIM: Vimentin 0.032 0.083
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.028
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.028
GTF3C1 N/A 0.032 0.028
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.165
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.032 0.028
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.165
AHR AHR: Aryl hydrocarbon receptor precursor 0.032 0.025
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.165
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.032 0.098
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.098
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.032 0.098
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.098
ACTG1 ACTB: Actin, cytoplasmic 1 0.032 0.044
PLD1 PLD1: Phospholipase D1 0.032 0.098
CRKL CRKL: Crk-like protein 0.032 46.90
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.032 0.049
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.098
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.031 0.047
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.031 0.483
EPOR EPOR: Erythropoietin receptor precursor 0.031 0.0688
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.031 0.0688
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.031 0.0688
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.031 0.0688
NFIB N/A 0.031 0.028
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.031 0.052
RFX1 RFX1: MHC class II regulatory factor RFX1 0.0308 0.075
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.0308 0.075
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.031 0.109
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.030 0.062
CNTN4 CNTN4: Contactin-4 precursor 0.030 0.062
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.030 0.483
CNTN1 CNTN1: Contactin-1 precursor 0.030 0.062
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.030 0.062
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.030 0.062
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.030 0.062
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.030 0.483
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.049
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.029 0.025
METTL1 METTL1, C12orf1: tRNA 0.029 0.025
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.029 0.075
JUND JUND: Transcription factor jun-D 0.029 0.075
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.029 0.025
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.025
CSDA CSDA, DBPA: DNA-binding protein A 0.029 0.025
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.029 0.075
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.028
SMCX JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C 0.029 0.025
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.148
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.029 0.148
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.029 0.025
RUNX1 N/A 0.029 0.025
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.148
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.029 0.025
TOP3A TOP3A, TOP3: DNA topoisomerase 3-alpha 0.029 0.025
WDR44 WDR44: WD repeat-containing protein 44 0.029 0.025
JUNB JUNB: Transcription factor jun-B 0.029 0.075
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.148
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.148
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.148
POLB POLB: DNA polymerase beta 0.029 0.025
BID BID: BH3-interacting domain death agonist 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.165
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.165
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.165
HES6 HES6: Transcription cofactor HES-6 0.028 0.083
ZNF265 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.165
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.148
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.028 0.165
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.028 0.025
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
C13orf8 N/A 0.028 0.028
DUSP15 N/A 0.028 0.028
RAB4A N/A 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.165
PHLDB2 N/A 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
IRF7 N/A 0.028 0.028
WDR54 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
KIF1B N/A 0.028 0.028
HDAC8 N/A 0.028 0.083
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.165
NES N/A 0.028 0.028
SNRPB N/A 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.148
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
MAPKAPK5 N/A 0.028 0.165
TFAP4 TFAP4: Transcription factor AP-4 0.028 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.148
CORO6 N/A 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.148
FLJ23436 N/A 0.028 0.025
DSP DSP: Desmoplakin 0.028 0.083
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.165
CABLES1 N/A 0.028 0.028
HDAC7A N/A 0.028 0.075
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.028 0.483
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.028 0.047
HIST2H2BE HIST2H2BE, H2BFQ: Histone H2B type 2-E 0.028 0.025
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.027 0.878
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.027 0.044
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.027 422.00
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.027 0.980
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.027 0.04
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.027 0.049
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.027 0.109
GAS2 GAS2: Growth arrest-specific protein 2 0.027 0.109
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.044
BMX N/A 0.0263 0.980
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.165
PRKAA1 N/A 0.026 0.165
GRLF1 N/A 0.026 0.083
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.028
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.026 0.165
MEF2A N/A 0.026 0.028
NUP214 N/A 0.026 0.028
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.026 0.025
MECP2 MECP2: Methyl-CpG-binding protein 2 0.026 0.028
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.028
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.026 0.028
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.025
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.028
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.083
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.026 0.148
KRT18 KRT18: Uncharacterized protein KRT18 0.026 0.028
ITGB4 N/A 0.025 0.0688
IL9R IL9R: Interleukin-9 receptor precursor 0.025 0.0688
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.025 0.0688
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.025 0.0688
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.148
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
SON 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
THOC4 THOC4, ALY, BEF: THO complex subunit 4 0.025 0.028
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.148
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.028
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.148
BCOR N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.028
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.148
KCTD1 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
MAX MAX: Protein max 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.165
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.148
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.148
PRKCB1 N/A 0.025 0.025
CREB1 CREB1: cAMP response element-binding protein 0.025 0.075
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.148
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.148
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.148
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
NUP98 N/A 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
SEC13L1 N/A 0.025 0.025
NIPBL N/A 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
ATXN2L N/A 0.025 0.025
ELMO1 N/A 0.025 0.148
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
GRK6 N/A 0.025 0.025
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
C20orf77 N/A 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.148
ADK ADK: Adenosine kinase 0.025 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.148
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.148
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.028
NPM3 NPM3: Nucleoplasmin-3 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
EXOSC3 EXOSC3, RRP40, CGI-102: Exosome complex exonuclease RRP40 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.148
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
HTATIP N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.052
DIDO1 N/A 0.025 0.028
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
TCEA1 N/A 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.148
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.148
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.148
0.228
Total Score 17.00