PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between TP53 and STAT6

The interaction score between TP53 and STAT6 is 13.20.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between TP53 and STAT6 = 0.53

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

6.27E-3

Orthology

Organism	TP53 Orthologue		STAT6 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
human	IPI00215713	0.16	IPI00030783	0.179
human	IPI00215713	0.16	IPI00103415	0.179
fly	Q8IH92	0.16	Q24151	0.108

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in TP53 and STAT6:

Domains in TP53

Domains in STAT6

IPR008967	p53-like transcription factor, DNA-binding
IPR002117	p53 tumor antigen
IPR010991	p53, tetramerisation
IPR011615	P53_DNA_bd.
IPR012346	P53_RUNT_DNA_bd.

IPR008967	p53-like transcription factor, DNA-binding
IPR000980	SH2 motif
IPR001217	STAT protein
IPR011992	EF-Hand_type.
IPR012345	STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in TP53 and STAT6 are listed below.

Domain 1		Domain 2		Chi Square
IPR002117	p53 tumor antigen	IPR000980	SH2 motif	4.72854
IPR010991	p53, tetramerisation	IPR000980	SH2 motif	4.72854
IPR011615	P53_DNA_bd.	IPR000980	SH2 motif	4.72854
IPR012346	P53_RUNT_DNA_bd.	IPR000980	SH2 motif	4.72854
IPR008967	p53-like transcription factor, DNA-binding	IPR000980	SH2 motif	0.942535

The background colour of the table refers to:

Blue Domain is only present in TP53
Yellow Domain is only present in STAT6
Green Domain is present in both TP53 and STAT6

0.049

Post-translational Modifications

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Protein: STAT6

PTM	Residue	Reference
Phosphorylation	641	PubMed, HPRD

Localisation

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Protein: STAT6

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between TP53 and STAT6 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andSTAT6. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and STAT6 has 1882 interactors of which there are 774 common interactors.

Common Interactor	Name of Common Interactor	Score for TP53-Interactor (?)	Score for STAT6-Interactor (?)
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	4.77	0.080
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	2.54	0.141
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	2.08	0.0818
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	1.58	0.033
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	1.26	0.041
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.964	0.145
NR4A2	NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2	0.902	0.041
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.822	0.0818
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.704	0.233
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.704	0.227
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.651	0.253
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.541	0.052
SP100	N/A	0.525	0.253
MCM3	MCM3: DNA replication licensing factor MCM3	0.515	0.054
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.503	0.275
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.503	0.461
SREBF2	N/A	0.475	0.027
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.471	0.041
NBN	NBN, NBS, NBS1, P95: Nibrin	0.430	0.253
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.430	0.091
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.430	0.124
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.430	0.101
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.430	0.127
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.430	0.153
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.430	0.0453
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.430	0.067
DDX21	DDX21: Nucleolar RNA helicase 2	0.430	0.153
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.425	0.181
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.385	0.0818
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.385	0.137
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.385	0.111
CCNB1	Cyclin B1	0.385	0.041
SP3	SP3: Transcription factor Sp3	0.347	0.112
SRF	SRF: Serum response factor	0.344	0.032
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.318	0.051
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.304	0.275
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.304	0.763
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.290	0.032
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.284	0.051
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.276	0.032
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.276	0.040
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.276	0.040
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.276	0.111
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.260	0.075
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.260	0.153
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.260	0.041
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.260	0.101
EP300	N/A	0.254	0.040
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.253	0.096
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.245	0.225
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.241	0.067
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.241	0.041
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.241	0.033
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.233	0.090
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.233	0.111
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.063
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.233	1.62
YY1	YY1: Transcriptional repressor protein YY1	0.233	0.185
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.233	0.137
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.227	0.139
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.216	0.067
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.216	0.385
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.210	0.137
RB1	RB1: Retinoblastoma-associated protein	0.210	0.091
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.210	0.057
ELF1	ELF1: ETS-related transcription factor Elf-1	0.210	0.541
MATR3	MATR3, KIAA0723: Matrin-3	0.210	0.074
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.208	0.032
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.188	0.227
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.188	0.137
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.188	0.233
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.188	0.0818
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.188	0.111
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.188	0.0818
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.188	0.112
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.137
CXorf9	N/A	0.188	1.62
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.188	0.137
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.188	0.112
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.187	131.00
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.172	0.137
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.172	0.041
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.162	0.0425
TP73	TP73, P73: Tumor protein p73	0.156	0.065
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.156	0.126
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.155	0.206
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.155	1.81
ZNF267	ZNF267: Zinc finger protein 267	0.155	0.101
ERF	ERF: ETS domain-containing transcription factor ERF	0.155	0.075
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.091
PSMD12	PSMD12: 26S proteasome non-ATPase regulatory subunit 12	0.148	0.037
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.111
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.146	0.071
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.146	0.066
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.146	0.054
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.146	0.033
PPP2CA	PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	0.145	0.114
ABCF1	N/A	0.144	0.070
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.144	0.070
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.144	0.515
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.144	0.036
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.144	0.0446
ESPL1	N/A	0.144	0.026
PTMA	N/A	0.144	0.0446
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.141	0.029
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.141	0.078
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.141	0.063
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.141	0.046
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.141	0.063
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.140	0.087
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.140	0.027
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.139	0.245
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.139	0.027
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.139	0.114
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.139	0.111
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.139	0.484
COPE	COPE: Coatomer subunit epsilon	0.139	0.063
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.139	0.227
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.139	0.041
RELA	RELA, NFKB3: Transcription factor p65	0.139	0.111
KIAA1012	KIAA1012: Protein TRS85 homolog	0.139	0.129
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.139	0.137
CDC23	CDC23: Cell division cycle protein 23 homolog	0.137	0.046
APRT	APRT: Adenine phosphoribosyltransferase	0.137	0.075
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.137	0.063
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.137	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.098
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.132	0.037
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.132	0.077
IRF3	IRF3: Interferon regulatory factor 3	0.132	0.340
CDK4	CDK4: Cell division protein kinase 4	0.129	0.171
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.129	0.032
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.129	0.275
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.129	0.032
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.129	0.032
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.129	0.040
HDAC3	HDAC3: Histone deacetylase 3	0.129	0.137
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.129	0.461
CBX3	CBX3: Chromobox protein homolog 3	0.129	0.032
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.129	0.040
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.129	0.032
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.129	0.032
NUP153	N/A	0.129	0.032
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.129	0.136
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.129	0.046
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.057
ZNF335	ZNF335: Zinc finger protein 335	0.127	0.067
ZFX	ZFX: Zinc finger X-chromosomal protein	0.127	0.061
HIVEP1	N/A	0.127	0.061
SALL1	SALL1, SAL1: Sal-like protein 1	0.125	0.031
ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2	0.124	0.056
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.118	0.067
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.118	0.461
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.118	0.041
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.114	0.090
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.063
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.114	0.181
ETS1	ETS1, EWSR2: Protein C-ets-1	0.114	0.0818
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.114	0.038
FKBP4	FKBP4: FK506-binding protein 4	0.114	0.056
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.114	0.078
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.114	1.62
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.029
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.114	0.054
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.114	0.461
CCNH	CCNH: Cyclin-H	0.114	0.051
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.114	0.090
MTF1	MTF1: Metal regulatory transcription factor 1	0.114	0.112
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.114	0.245
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.114	0.227
AIP	AIP, XAP2: AH receptor-interacting protein	0.114	0.188
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.114	0.385
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.114	0.114
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.114	330.00
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.114	0.097
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.114	0.067
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.112	0.139
CSK	CSK: Tyrosine-protein kinase CSK	0.112	12.80
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.112	6.03
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.111	0.069
HSP90AA1	Hsp89-alpha-delta-N	0.111	0.086
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.111	12.80
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.102	0.067
GTF2F2	N/A	0.0971	0.075
VARS	VARS, G7A, VARS2: Valyl-tRNA synthetase	0.0968	0.036
PSMD3	PSMD3: 26S proteasome non-ATPase regulatory subunit 3	0.0968	0.036
PSMD13	PSMD13: 26S proteasome non-ATPase regulatory subunit 13	0.0968	0.074
hfl-B5	PCID1, EIF3M, GA17, hfl-B5, hCG_27316: PCI domain containing 1	0.0968	0.074
STAT2	STAT2: Signal transducer and activator of transcription 2	0.096	0.166
NFATC1	N/A	0.096	0.124
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.096	0.037
EEA1	EEA1, ZFYVE2: Early endosome antigen 1	0.096	0.071
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.096	0.561
PDK1	PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu	0.094	0.046
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.093	0.078
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.087	0.191
GNB2L1	Lung cancer oncogene 7	0.087	0.074
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.074
NCOA3	N/A	0.087	0.074
SET	SET: Protein SET	0.087	0.027
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.036
TCOF1	N/A	0.087	0.027
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.087	0.036
IFI16	N/A	0.087	0.157
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.087	0.153
TGIF2	TGIF2: Homeobox protein TGIF2	0.087	0.0446
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.087	0.036
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.087	0.188
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.087	0.071
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.087	0.032
SOX4	SOX4: Transcription factor SOX-4	0.086	0.033
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.086	0.137
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.086	0.0818
BRPF1	BRPF1, BR140: Peregrin	0.086	0.139
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.086	0.372
MLL	MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX	0.086	0.051
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.086	0.041
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.086	0.0818
CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1	0.086	0.029
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.086	0.067
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.086	0.111
CREBBP	CREBBP, CBP: CREB-binding protein	0.086	66.00
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.086	0.029
ATM	ATM: Serine-protein kinase ATM	0.086	0.275
GHR	GHR: Growth hormone receptor precursor	0.085	0.100
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.084	0.032
PPEF1	N/A	0.083	0.165
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.165
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.083	0.04
MAPK15	N/A	0.083	0.165
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.049
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.083	0.04
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.083	0.04
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.148
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.083	0.04
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.049
ZNF579	ZNF579: Zinc finger protein 579	0.083	0.04
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.083	0.083
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.083	0.04
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.083	0.049
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.049
NAPG	NAPG, SNAPG: Gamma-soluble NSF attachment protein	0.0818	0.038
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.0818	0.056
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.0818	0.146
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.081	0.097
H1FX	H1FX: Histone H1x	0.080	0.153
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.040
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.078	0.066
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.078	0.040
FNBP1	N/A	0.078	0.763
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.032
CDK2	CDK2: Cell division protein kinase 2	0.078	0.171
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.078	0.066
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.040
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.078	0.040
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.078	0.032
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.078	0.032
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.078	0.090
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.078	0.040
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.040
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.066
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.078	0.040
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.078	0.111
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.461
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.040
CDK7	CDK7, MO15: Cell division protein kinase 7	0.078	0.225
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.763
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.078	0.304
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.078	0.078
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.078	0.040
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.040
ETS2	ETS2: Protein C-ets-2	0.077	0.166
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.123
BRIP1	BRIP1, BACH1, FANCJ: Fanconi anemia group J protein	0.077	0.033
ERG	ERG: Transcriptional regulator ERG	0.077	0.037
SNAI1	SNAI1, SNAH: Zinc finger protein SNAI1	0.077	0.033
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.077	0.046
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.077	0.210
ROBO1	ROBO1, DUTT1: Roundabout homolog 1 precursor	0.076	0.073
EEF2	EEF2, EF2: Elongation factor 2	0.075	0.063
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.075	0.036
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.075	0.044
BRD4	N/A	0.075	0.044
SOX8	SOX8: Transcription factor SOX-8	0.075	0.036
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.075	0.098
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.075	0.036
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.075	0.036
GIT2	N/A	0.075	0.075
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.075	0.036
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.075	0.044
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.075	0.075
CCNT2	CCNT2: Cyclin-T2	0.075	0.044
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	0.148
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.075	0.036
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.044
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.075	0.044
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.075	0.044
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.075	0.036
PTP4A3	PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3	0.075	0.050
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	0.148
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.044
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.044
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.074	1.98
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.074	0.063
PHB2	PHB2, BAP, REA: Prohibitin-2	0.074	0.0971
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.074	0.060
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.071	0.0818
PTPN1	PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1	0.071	0.181
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.070	0.416
WDR1	N/A	0.070	0.074
PLEK	PLEK, P47: Pleckstrin	0.070	0.561
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.070	0.032
STK16	N/A	0.070	0.251
KIAA0853	N/A	0.070	0.036
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.027
API5	N/A	0.070	0.0425
UBAP2	N/A	0.070	0.032
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.074
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.070
ZNF551	N/A	0.069	0.033
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.069	0.041
LIG4	LIG4: DNA ligase 4	0.069	0.033
GCN5L2	GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2	0.069	0.033
PTP4A1	PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1	0.069	0.058
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.069
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.069	0.054
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.069	0.372
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.069	0.090
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.069	0.503
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.069	0.137
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.067	0.233
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.067	370.00
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.067	0.275
SYK	SYK: Tyrosine-protein kinase SYK	0.067	6.03
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.066	0.763
HSPD1		0.066	0.029
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.066	0.038
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.066	0.233
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.063
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.066	0.038
QARS	QARS: Glutaminyl-tRNA synthetase	0.066	0.129
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.066	0.139
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.066	0.063
CTPS	CTPS: CTP synthase 1	0.066	0.029
CCT8	CCT8: Uncharacterized protein CCT8	0.066	0.046
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.066	0.038
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.066	0.129
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.066	0.038
HNRPK	N/A	0.066	0.129
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.066	0.046
GPI	GPI: Glucose-6-phosphate isomerase	0.066	0.038
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.066	0.038
MTHFD1	MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic	0.066	0.029
NMI	NMI: N-myc-interactor	0.065	0.137
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.063	0.063
CORO1C	CORO1C, CRNN4: Coronin-1C	0.063	0.032
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.063	0.040
PPP1R8	N/A	0.063	0.040
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.078
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.137
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.029
RPS6KB1	N/A	0.063	0.461
SEC31L1	N/A	0.063	0.032
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.129
WBSCR20A	N/A	0.063	0.040
PHF10	N/A	0.063	0.032
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.063	0.225
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.063	0.763
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.063	1.07
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.066
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.063	0.032
MYH9	MYH9: Myosin-9	0.063	0.304
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.063	0.032
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.067
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.063	0.111
COPA	COPA: Coatomer subunit alpha	0.063	0.063
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.063	0.040
RAB8A	RAB8A: RAB8A protein	0.063	0.112
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.129
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.032
WEE1	WEE1: Wee1-like protein kinase	0.063	0.136
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.461
CRLF3	N/A	0.063	1.19
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.062	0.0453
SH3BP3		0.062	0.061
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.062	0.032
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.062	0.037
PTPN2	PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2	0.062	46.90
LYN	LYN: Tyrosine-protein kinase Lyn	0.061	12.80
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.061	1.98
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.061	1.20
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.060	0.0818
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.075
EIF3S10	EIF3S10, KIAA0139: Eukaryotic translation initiation factor 3 subunit 10	0.059	0.074
COPS2	N/A	0.059	0.060
COPS7B	COPS7B, CSN7B: COP9 signalosome complex subunit 7b	0.059	0.074
S100B	S100B: Protein S100-B	0.058	0.049
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.057	0.155
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.057	0.171
COL7A1	COL7A1: Collagen alpha-1(VII) chain precursor	0.057	0.041
MYCBP2	MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2	0.056	0.040
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.056	0.171
PCAF	PCAF: Histone acetyltransferase PCAF	0.056	0.041
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.056	0.0818
SP1	SP1, TSFP1: Transcription factor Sp1	0.056	0.033
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.056	0.111
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.056	0.073
ETV1	ETV1, ER81: ETS translocation variant 1	0.056	0.026
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.0554	0.276
NFKBIB	NFKBIB, IKBB, TRIP9: NF-kappa-B inhibitor beta	0.055	0.055
STAT4	STAT4: Signal transducer and activator of transcription 4	0.055	17.10
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.055	0.072
TAF1	TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1	0.055	0.029
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.054	0.038
SOS1	SOS1: Son of sevenless homolog 1	0.054	0.181
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.054	0.033
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.049
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.049
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.052	0.026
CHUK	N/A	0.052	0.052
TOP2B	N/A	0.052	0.027
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.036
TRRAP	N/A	0.052	0.0425
ARFGAP1	N/A	0.052	0.101
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.515
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.052	0.036
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.0446
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.027
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.052
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.052	0.052
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.070
RP11-98F14.6	N/A	0.051	0.051
JAK1		0.051	3.64
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.051	0.171
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.051	2.90E3
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.051	0.136
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.165
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.049	0.165
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.049	0.083
STAT3		0.049	22.50
NASP	NASP: Nuclear autoantigenic sperm protein	0.049	0.028
S100A16	S100A16, AAG13: Protein S100-A16	0.049	0.083
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.165
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.049	0.136
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.049	65.60
ELK1	ELK1: ETS domain-containing protein Elk-1	0.049	0.026
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.048	0.101
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.048	0.100
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.048	0.030
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.044
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.047	0.098
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.047	0.044
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.047	0.047
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.461
SAPS3	N/A	0.046	0.063
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.372
SYMPK	SYMPK, SPK: Symplekin	0.046	0.029
CUL5	CUL5, VACM1: Cullin-5	0.046	0.032
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.040
MDN1	MDN1, KIAA0301: Midasin	0.046	0.038
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.461
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.046	0.111
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.046	0.111
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.046	0.136
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.046	0.040
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.423
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.046	0.461
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.063
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.066
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.046	0.032
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.046	0.372
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.090
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	0.090
DIAPH1	Diaphanous 1	0.046	0.129
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.046	0.141
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.046	0.225
DOK1	DOK1: Docking protein 1	0.046	0.763
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.078
KLHDC4	N/A	0.046	0.063
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.046	0.032
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	1.62
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.372
CUL4B	N/A	0.046	0.032
GSK3B	N/A	0.046	0.078
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.046	0.763
PPP2CB	PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	0.0462	21.30
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.046	0.096
HSP90B1	HSP90B1, TRA1: Endoplasmin precursor	0.046	0.056
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.0453	0.026
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.0453	0.260
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.0446	0.307
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.0446	0.026
FUBP1	N/A	0.0446	0.260
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.044	0.088
EGR1	EGR1, ZNF225: Early growth response protein 1	0.044	0.033
DUSP3	DUSP3, VHR: Dual specificity protein phosphatase 3	0.044	0.065
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.044	0.148
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.044	0.075
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.043	0.032
VDR	VDR, NR1I1: Vitamin D3 receptor	0.043	0.054
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.043	0.041
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.0425	0.166
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.027
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.0425	0.087
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.0425	0.152
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.0425	0.852
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.070
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.070
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.0425	0.416
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.0425	0.515
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.0425	0.191
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.0425	0.073
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.027
RGS14	N/A	0.0425	0.036
MARK2	N/A	0.0425	0.144
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.041	12.80
EXOC2	N/A	0.041	0.139
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.041	0.029
STUB1	STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1	0.041	0.029
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.04	1.30
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.04	1.30
LCP1	LCP1, PLS2: Plastin-2	0.040	1.62
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.040	0.822
CD2AP	CD2AP: CD2-associated protein	0.040	0.372
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.040	0.078
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.040	0.078
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.040	0.046
LDHB	LDHB: L-lactate dehydrogenase B chain	0.040	0.038
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.040	0.171
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.040	0.063
THOP1	THOP1: Thimet oligopeptidase	0.040	0.038
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.040	0.046
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.040	0.385
RPL8	RPL8: 60S ribosomal protein L8	0.040	0.078
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.040	0.129
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.040	0.385
HRB2	KRR1, HRB2: KRR1 small subunit processome component homolog	0.040	0.037
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.040	0.038
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.040	0.078
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.040	0.078
LPXN	LPXN, LDLP: Leupaxin	0.040	0.385
XPO1	XPO1, CRM1: Exportin-1	0.040	0.063
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.039	1.20
PPARG	CREB3L2-PPARgamma	0.039	0.027
CEP110	CEP1: 110 kDa centrosomal protein	0.039	0.050
SORL1	SORL1: Sortilin-related receptor precursor	0.039	0.561
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.039	0.274
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.038	0.763
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.461
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.038	0.372
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.038	0.304
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.038	0.032
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.038	0.225
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.038	0.372
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.046
STK10	STK10: Uncharacterized protein STK10	0.038	1.62
MAFG	MAFG: Transcription factor MafG	0.038	0.051
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.038	0.139
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.038	0.032
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.038	0.461
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.038	0.066
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.037	0.859
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.037	0.694
S100A3	S100A3, S100E: Protein S100-A3	0.037	0.049
SAFB2	SAFB2, KIAA0138: Scaffold attachment factor B2	0.036	0.061
SRPR	SRPR: Uncharacterized protein SRPR	0.036	0.087
HD	HD, IT15: Huntingtin	0.036	0.070
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.036	0.307
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.036	0.0425
LIMS1	N/A	0.036	0.260
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.036	0.852
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.036	0.191
TMSB4X	TMSB4X, TB4X, THYB4, TMSB4: Thymosin beta-4	0.036	0.161
IFI35	N/A	0.036	0.144
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.036	0.025
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.036	1.17
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.036	1.17
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.036	1.17
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.035	0.029
COPS4	COPS4, CSN4: COP9 signalosome complex subunit 4	0.035	0.028
FOXL2	FOXL2: Forkhead box protein L2	0.034	0.026
SCML2	SCML2: Sex comb on midleg-like protein 2	0.034	0.0727
FN1	N/A	0.034	0.109
PTPRR	PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor	0.034	0.109
PTPRS	PTPRS: Receptor-type tyrosine-protein phosphatase S precursor	0.034	0.109
MDGA1	MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein	0.034	0.109
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.034	0.980
RAD18	RAD18, RNF73: E3 ubiquitin-protein ligase RAD18	0.034	0.034
TRPV1	TRPV1: Vanilloid receptor variant TRPV1b	0.034	0.109
IL6ST	IL6ST: Interleukin-6 receptor subunit beta precursor	0.034	0.109
IL4R	IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor	0.034	0.109
LEPR	LEPR, DB, OBR: Leptin receptor precursor	0.034	0.109
TRPV4	TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb	0.034	0.109
IL6R	IL6R: Interleukin-6 receptor alpha chain precursor	0.034	0.0688
PTPRC	PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ	0.034	0.109
PTPRE	PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor	0.034	0.109
AXIN1		0.0333	0.083
YWHAG	YWHAG: 14-3-3 protein gamma	0.0333	0.028
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.033	0.770
HCK	N/A	0.033	6.03
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.033	856.00
MAGED2	N/A	0.033	0.056
S100A7	S100A7, PSOR1: Protein S100-A7	0.032	0.055
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.032	0.775
BACH1	BACH1: Transcription regulator protein BACH1	0.032	0.253
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.032	0.087
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.032	0.307
ID2	ID2: DNA-binding protein inhibitor ID-2	0.032	0.0446
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.032	0.307
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.416
VIM	VIM: Vimentin	0.032	0.124
GTF3C1	N/A	0.032	0.027
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.032	0.416
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.032	0.251
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.032	0.251
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.032	0.827
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.032	0.038
FRG1	FRG1: Protein FRG1	0.032	0.078
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.032	0.129
CLIC1	CLIC1, NCC27: Chloride intracellular channel protein 1	0.032	0.048
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.275
RPS10	RPS10: 40S ribosomal protein S10	0.032	0.129
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.032	0.078
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.032	0.763
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.032	0.078
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.032	4.88
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.029
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.032	0.046
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	0.078
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.032	0.763
ACTG1	ACTB: Actin, cytoplasmic 1	0.032	0.822
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.032	0.063
FLII	FLII, FLIL: Protein flightless-1 homolog	0.032	0.129
PLD1	PLD1: Phospholipase D1	0.032	0.136
PREP	PREP, PEP: Prolyl endopeptidase	0.032	0.063
PPARBP	N/A	0.032	0.078
RAB11A	RAB11A, RAB11: Ras-related protein Rab-11A	0.032	0.037
CRKL	CRKL: Crk-like protein	0.032	132.00
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.139
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.038
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.032	1.62
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.063
CUL2	CUL2: Cullin-2	0.032	0.026
FLT3	FLT3, STK1: FL cytokine receptor precursor	0.031	0.808
EPOR	EPOR: Erythropoietin receptor precursor	0.031	0.081
IL12B	IL12B, NKSF2: Interleukin-12 subunit beta precursor	0.031	0.051
MPL	MPL, TPOR: Thrombopoietin receptor precursor	0.031	0.072
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.031	0.166
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.031	0.027
RFX1	RFX1: MHC class II regulatory factor RFX1	0.0308	0.029
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.0308	0.029
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	0.031	0.152
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.030	0.098
CNTN4	CNTN4: Contactin-4 precursor	0.030	0.098
EPHA8	EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor	0.030	0.878
CNTN1	CNTN1: Contactin-1 precursor	0.030	0.098
L1CAM	L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor	0.030	0.098
TRPV6	TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6	0.030	0.098
EPHA5	EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor	0.030	0.483
FKBP8	DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment)	0.029	0.049
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.029	0.0818
JUND	JUND: Transcription factor jun-D	0.029	0.227
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.029	0.111
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.171
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.029	0.275
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.029	0.038
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.029	0.372
WDR44	WDR44: WD repeat-containing protein 44	0.029	0.032
JUNB	JUNB: Transcription factor jun-B	0.029	0.484
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.029	0.171
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.029	0.225
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.029	0.275
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.165
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.165
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.165
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.028	0.165
NF2	NF2, SCH: Merlin	0.028	0.165
HES6	HES6: Transcription cofactor HES-6	0.028	0.049
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.165
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.028	0.148
PRKACB	PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit	0.028	0.056
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.083
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.165
PHLDB2	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
HDAC8	N/A	0.028	0.049
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.165
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.028	0.148
MAPKAPK5	N/A	0.028	0.165
CDC2	CDC2: Cell division control protein 2 homolog	0.028	0.148
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.028	0.148
DSP	DSP: Desmoplakin	0.028	0.049
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.109
HDAC7A	N/A	0.028	0.044
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
EPHA2	EPHA2, ECK: Ephrin type-A receptor 2 precursor	0.028	0.655
NOTCH2	NOTCH2: Neurogenic locus notch homolog protein 2 precursor	0.028	0.137
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.027	0.874
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.027	0.049
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.027	420.00
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.027	1.78
CAPNS1	CAPNS1, CAPN4, CAPNS: Calpain small subunit 1	0.027	0.044
GSTP1	GSTP1, FAEES3, GST3: Glutathione S-transferase P	0.027	0.038
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.027	0.070
MPG	N/A	0.027	0.070
NAT1	NAT1, AAC1: Arylamine N-acetyltransferase 1	0.027	0.052
TRADD	TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein	0.027	0.430
LASP1	LASP1, MLN50: LIM and SH3 domain protein 1	0.027	0.287
GAS2	GAS2: Growth arrest-specific protein 2	0.027	0.152
YWHAQ	YWHAQ: 14-3-3 protein theta	0.027	0.032
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.027	0.070
FABP5	FABP5: Fatty acid-binding protein, epidermal	0.027	0.056
BMX	N/A	0.0263	0.775
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.026	0.109
PRKAA1	N/A	0.026	0.191
GRLF1	N/A	0.026	0.055
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.026	0.191
MEF2A	N/A	0.026	0.027
NUP214	N/A	0.026	0.036
ZFP36	ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline	0.026	0.066
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.026
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.026	0.078
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
TRIM16	TRIM16, EBBP: Tripartite motif-containing protein 16	0.026	0.055
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.026	0.088
PARP4	PARP4, ADPRTL1, KIAA0177, PARPL: Poly [ADP-ribose] polymerase 4	0.0255	0.027
ITGB4	N/A	0.025	0.072
IL9R	IL9R: Interleukin-9 receptor precursor	0.025	0.081
IL12RB2	IL12RB2: Interleukin-12 receptor beta-2 chain precursor	0.025	0.100
IFNAR1	IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor	0.025	0.126
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.148
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.148
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.148
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.148
BCOR	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.098
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.148
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.148
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.148
PRKCB1	N/A	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.044
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.098
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.148
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.044
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.148
NIPBL	N/A	0.025	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
ELMO1	N/A	0.025	0.148
GRK6	N/A	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.098
ADK	ADK: Adenosine kinase	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.148
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.148
CAMK2A	N/A	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.148
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.036
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.148
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.098
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.148
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.148
C11orf58	SMAP, C11orf58: Small acidic protein	0.025	0.025

0.299

Total Score

13.20