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Evidence of Interaction Between TP53 and NR4A2

The interaction score between TP53 and NR4A2 is 82.10.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TP53 and NR4A2 = -0.04

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismTP53 OrthologueNR4A2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00215713 0.16 IPI00027454 0.391
human IPI00215713 0.16 IPI00334557 0.432
fly Q8IH92 0.16 P49869 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in TP53 and NR4A2:
Domains in TP53Domains in NR4A2
IPR008967 p53-like transcription factor, DNA-binding
IPR002117 p53 tumor antigen
IPR010991 p53, tetramerisation
IPR011615 P53_DNA_bd.
IPR012346 P53_RUNT_DNA_bd.
IPR000536 Ligand-binding domain of nuclear hormone receptor
IPR001628 Zn-finger, C4-type steroid receptor
IPR001723 Steroid hormone receptor
IPR008946 Steroid nuclear receptor, ligand-binding
IPR003070 Orphan nuclear receptor
IPR003073 Orphan nuclear receptor, NURR type

The Chi square scores for co-occurrence of domains that are present in TP53 and NR4A2 are listed below.

Domain 1Domain 2Chi Square
IPR008967 p53-like transcription factor, DNA-binding IPR001723 Steroid hormone receptor 0.930296
IPR008967 p53-like transcription factor, DNA-binding IPR001628 Zn-finger, C4-type steroid receptor 0.881474
IPR008967 p53-like transcription factor, DNA-binding IPR000536 Ligand-binding domain of nuclear hormone receptor 0.865601
IPR011615 P53_DNA_bd. IPR001723 Steroid hormone receptor 0.0229703
IPR010991 p53, tetramerisation IPR001723 Steroid hormone receptor 0.0229703
IPR002117 p53 tumor antigen IPR001723 Steroid hormone receptor 0.0229703
IPR012346 P53_RUNT_DNA_bd. IPR001723 Steroid hormone receptor 0.0229703
IPR010991 p53, tetramerisation IPR001628 Zn-finger, C4-type steroid receptor 0.0176841
IPR011615 P53_DNA_bd. IPR001628 Zn-finger, C4-type steroid receptor 0.0176841
IPR012346 P53_RUNT_DNA_bd. IPR001628 Zn-finger, C4-type steroid receptor 0.0176841
IPR002117 p53 tumor antigen IPR001628 Zn-finger, C4-type steroid receptor 0.0176841
IPR012346 P53_RUNT_DNA_bd. IPR000536 Ligand-binding domain of nuclear hormone receptor 0.0160854
IPR011615 P53_DNA_bd. IPR000536 Ligand-binding domain of nuclear hormone receptor 0.0160854
IPR010991 p53, tetramerisation IPR000536 Ligand-binding domain of nuclear hormone receptor 0.0160854
IPR002117 p53 tumor antigen IPR000536 Ligand-binding domain of nuclear hormone receptor 0.0160854

The background colour of the table refers to:

  • Blue Domain is only present in TP53
  • Yellow Domain is only present in NR4A2
  • Green Domain is present in both TP53 and NR4A2

 1.53
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: NR4A2

PTMResidueReference
Sumoylation 91 PubMed, HPRD
Sumoylation 577 PubMed, HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: NR4A2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and NR4A2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andNR4A2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and NR4A2 has 700 interactors of which there are 521 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for NR4A2-Interactor (?)
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 2.54 0.029
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.171
HIST1H1B HIST1H1B, H1F5: Histone H1.5 1.26 0.126
PGR PGR, NR3C3: Progesterone receptor 1.00 0.109
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 0.0898
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.049
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.102
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.704 0.069
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.152
SP100 N/A 0.525 0.077
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.503 0.029
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.503 0.033
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.049
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.055
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.123
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.096
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.109
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.123
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.062
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.055
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.425 0.0898
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.056
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.111
CCNB1 Cyclin B1 0.385 0.044
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.056
SP3 SP3: Transcription factor Sp3 0.347 0.056
SRF SRF: Serum response factor 0.344 0.056
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.304 0.029
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.035
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.035
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.077
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.062
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.123
EP300 N/A 0.254 0.208
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.253 0.032
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.245 0.033
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.056
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.069
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.136
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.056
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.216 0.078
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.216 0.086
RB1 RB1: Retinoblastoma-associated protein 0.210 0.077
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.111
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.032
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.062
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.109
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.208 0.171
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.111
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.069
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.188 0.049
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.069
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.114
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.086
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.049
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.188 0.111
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.069
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.187 0.047
MYB MYB: Myb proto-oncogene protein 0.176 0.123
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.172 0.049
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.172 0.069
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.156 0.062
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.096
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.155 0.026
AR AR, DHTR, NR3C4: Androgen receptor 0.152 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.152 0.165
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.152
MITF MITF: Microphthalmia-associated transcription factor 0.152 0.028
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.146 0.044
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.048
PTMA N/A 0.144 0.026
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.141 1.77
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.141 0.027
SAT SAT1, SAT: Diamine acetyltransferase 1 0.140 0.032
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.140 0.056
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.114
COPE COPE: Coatomer subunit epsilon 0.139 0.056
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.139 0.171
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.049
RELA RELA, NFKB3: Transcription factor p65 0.139 0.056
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.086
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.056
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.139 0.049
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.049
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.139 0.056
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.137 0.033
CDC23 CDC23: Cell division cycle protein 23 homolog 0.137 6.09
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.137 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 1.37
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 1.37
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.137 0.148
SSB SSB: Lupus La protein 0.129 0.035
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.035
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.049
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.069
HIVEP1 N/A 0.127 0.055
ZNF335 ZNF335: Zinc finger protein 335 0.127 0.069
ZFX ZFX: Zinc finger X-chromosomal protein 0.127 0.062
SALL1 SALL1, SAL1: Sal-like protein 1 0.125 0.049
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.064
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.118 0.049
MTF1 MTF1: Metal regulatory transcription factor 1 0.114 0.114
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.114 0.118
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.056
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.114 0.037
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 0.043
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.114 0.044
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.069
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.114 0.069
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.136
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.114 0.056
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.056
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.044
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.114 0.056
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.029
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.056
CCNH CCNH: Cyclin-H 0.114 0.049
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.111 0.049
HSP90AA1 Hsp89-alpha-delta-N 0.111 0.033
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.041
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.102 0.086
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.086
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.096 0.026
NFATC1 N/A 0.096 0.077
STAT2 STAT2: Signal transducer and activator of transcription 2 0.096 0.060
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.096 0.055
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.090 0.111
TGIF2 TGIF2: Homeobox protein TGIF2 0.087 0.123
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.087 0.077
UNG N/A 0.087 0.111
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.048
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.048
NCOA3 N/A 0.087 0.026
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.034
IFI16 N/A 0.087 0.026
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.049
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.086 0.086
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.086 0.049
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.056
CREBBP CREBBP, CBP: CREB-binding protein 0.086 65.60
SOX4 SOX4: Transcription factor SOX-4 0.086 0.056
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.086 0.069
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.086 0.171
BRPF1 BRPF1, BR140: Peregrin 0.086 0.136
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.069
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.086 0.111
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.083
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
UHRF1 0.083 0.165
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.075
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.165
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.165
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.083
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
PPEF1 N/A 0.083 0.028
C20orf18 N/A 0.083 0.165
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.083
MAPK15 N/A 0.083 0.083
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.083
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.028
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.0818 0.033
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.073
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.088
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.029
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.078 0.049
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.054
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.043
FNBP1 N/A 0.078 0.136
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.078 0.035
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.035
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.078 0.136
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.043
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.043
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.077 0.056
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.077 0.077
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.077 0.026
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.062
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.069
ETS2 ETS2: Protein C-ets-2 0.077 0.032
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.075
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.148
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.075 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.047
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.075 0.075
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.075
RNF20 0.075 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.075 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.075 0.047
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.075 0.075
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.148
BRD4 N/A 0.075 0.148
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.148
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.075
SOX8 SOX8: Transcription factor SOX-8 0.075 0.075
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.075 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.025
GIT2 N/A 0.075 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.075
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.075
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.075 0.025
CCNT2 CCNT2: Cyclin-T2 0.075 0.047
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.026
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.026
WDR1 N/A 0.070 0.026
PLEK PLEK, P47: Pleckstrin 0.070 0.026
KIAA0853 N/A 0.070 0.026
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.069 0.188
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.069 0.046
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.069 0.069
ZNF551 N/A 0.069 0.069
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.069 15.70
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.069 0.056
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.069 0.275
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.069 0.049
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.033
SUMO2 SUMO2, SMT3B, SMT3H2: Small ubiquitin-related modifier 2 precursor 0.0668 0.028
VCP VCP: Transitional endoplasmic reticulum ATPase 0.066 0.041
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.056
COPA COPA: Coatomer subunit alpha 0.063 0.029
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.136
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.097
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.063 0.029
RBM7 0.063 0.0308
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.069
RPS6KB1 N/A 0.063 0.029
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.029
PHF10 N/A 0.063 0.136
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.035
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.055
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.123
SH3BP3 0.062 0.077
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.060 0.056
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.096
FAM82B FAM82B, CGI-90: Protein FAM82B 0.057 0.640
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.056 0.071
SP1 SP1, TSFP1: Transcription factor Sp1 0.056 0.069
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.029
PCAF PCAF: Histone acetyltransferase PCAF 0.056 0.111
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.056 0.139
HCC-1 HCC1, HSPC316: Nuclear protein Hcc-1 0.055 0.0416
STAT4 STAT4: Signal transducer and activator of transcription 4 0.055 0.0308
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.055 0.109
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.054 0.097
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.083
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.028
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.123
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.152
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.026
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.039
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.032
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.039
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.109
TOP2B N/A 0.052 0.026
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.026
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.026
EMD EMD, EDMD, STA: Emerin 0.052 0.026
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.051 0.033
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.067
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.050 0.037
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.049 0.123
NASP NASP: Nuclear autoantigenic sperm protein 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.049
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.049
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.109
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 23.60
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.049
SOX11 SOX11: Transcription factor SOX-11 0.049 0.056
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.049 0.056
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.049 0.044
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.048 0.191
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.048 0.152
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.047 0.025
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.047 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.047 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.047 0.025
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.029
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.069
DIAPH1 Diaphanous 1 0.046 0.029
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.171
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.046 11.10
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.029
GSK3B N/A 0.046 0.029
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.071
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.029
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.046 0.035
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.046 0.049
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.046 0.038
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.029
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.046 0.0308
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.046 0.028
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0446 0.065
KLC2 KLC2: Kinesin light chain 2 0.044 0.049
EGR1 EGR1, ZNF225: Early growth response protein 1 0.044 0.385
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.044 0.026
VDR VDR, NR1I1: Vitamin D3 receptor 0.043 0.225
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.043 0.056
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.109
MARK2 N/A 0.0425 0.026
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.048
RGS14 N/A 0.0425 0.026
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.026
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.0425 0.152
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.026
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.026
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.109
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.026
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.052
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.026
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.127
EXOC2 N/A 0.041 0.033
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.041 0.033
ETF1 ETF1, ERF1, RF1, SUP45L1: Eukaryotic peptide chain release factor subunit 1 0.040 0.036
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.040 6.09
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.040 0.064
PPARG CREB3L2-PPARgamma 0.039 0.097
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.039 0.026
MAFG MAFG: Transcription factor MafG 0.038 0.086
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.038 0.029
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.049
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.038 0.029
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.038 0.054
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.038
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.038 0.029
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.029
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.038 0.054
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.136
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.038 0.054
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.038 0.069
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.035
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.171
SAFB2 SAFB2, KIAA0138: Scaffold attachment factor B2 0.036 0.042
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.100
HD HD, IT15: Huntingtin 0.036 0.081
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.035 0.097
FOXL2 FOXL2: Forkhead box protein L2 0.034 0.056
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.0688
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.033 0.064
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.026
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.060
VIM VIM: Vimentin 0.032 0.026
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.123
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.032 0.055
AHR AHR: Aryl hydrocarbon receptor precursor 0.032 0.275
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.032
BACH1 BACH1: Transcription regulator protein BACH1 0.032 0.096
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.026
ID2 ID2: DNA-binding protein inhibitor ID-2 0.032 0.127
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.031 0.097
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.031 0.109
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.030 0.062
RUNX1 N/A 0.029 0.029
WDR44 WDR44: WD repeat-containing protein 44 0.029 0.029
JUNB JUNB: Transcription factor jun-B 0.029 0.139
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.029 0.035
METTL1 METTL1, C12orf1: tRNA 0.029 0.097
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.029 0.069
JUND JUND: Transcription factor jun-D 0.029 0.139
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.029 0.056
SMCX JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C 0.029 0.097
IRF7 N/A 0.028 0.028
RAB4A N/A 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.052
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
KIF1B N/A 0.028 0.028
HDAC8 N/A 0.028 0.083
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.165
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.025
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
NES N/A 0.028 0.028
SNRPB N/A 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.025
MAPKAPK5 N/A 0.028 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.028 0.075
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.025
CORO6 N/A 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
FLJ23436 N/A 0.028 0.025
DSP DSP: Desmoplakin 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
CABLES1 N/A 0.028 0.028
HDAC7A N/A 0.028 0.075
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.083
ZNF265 N/A 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.165
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.052
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.165
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.025
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.165
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
C13orf8 N/A 0.028 0.028
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.028 0.148
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.052
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.028 0.461
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.026
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.038
MECP2 MECP2: Methyl-CpG-binding protein 2 0.026 0.026
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.109
KRT18 KRT18: Uncharacterized protein KRT18 0.026 0.098
NUP214 N/A 0.026 0.026
MEF2A N/A 0.026 0.096
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.026 0.063
ATXN7 ATXN7, SCA7: Ataxin-7 0.0253 0.0253
CIC CIC, KIAA0306: Protein capicua homolog 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
GRK6 N/A 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
NUP98 N/A 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
SEC13L1 N/A 0.025 0.025
NIPBL N/A 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.047
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.148
ATXN2L N/A 0.025 0.025
ELMO1 N/A 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.148
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.047
C20orf77 N/A 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.075
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
HTATIP N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.075
DIDO1 N/A 0.025 0.148
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.047
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.025
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.047
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.047
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
TCEA1 N/A 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
MAP2K3 N/A 0.025 2.14
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.047
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.047
SON 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.148
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.148
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.075
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.025
BCOR N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
KCTD1 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
MAX MAX: Protein max 0.025 0.075
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.148
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.148
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 12.00
PRKCB1 N/A 0.025 0.025
CREB1 CREB1: cAMP response element-binding protein 0.025 0.075
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 4.64
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.148
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.025 0.0338
0.228
Total Score 82.10