Home
Advanced Search
Help
Update History
Statistics
Downloads
The Barton Group
<<< Back to TP53

Evidence of Interaction Between TP53 and KPNA2

The interaction score between TP53 and KPNA2 is 10.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TP53 and KPNA2 = 0.58

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 6.27E-3
Orthology
OrganismTP53 OrthologueKPNA2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00215713 0.16 IPI00002214 1
human IPI00215713 0.16 IPI00374362 0.069
fly Q8IH92 0.16 P52295 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in TP53 and KPNA2:
Domains in TP53Domains in KPNA2
IPR008967 p53-like transcription factor, DNA-binding
IPR002117 p53 tumor antigen
IPR010991 p53, tetramerisation
IPR011615 P53_DNA_bd.
IPR012346 P53_RUNT_DNA_bd.
IPR000225 Armadillo
IPR002652 Importin alpha-like protein, beta-binding region
IPR011989 ARM-like.

The Chi square scores for co-occurrence of domains that are present in TP53 and KPNA2 are listed below.

Domain 1Domain 2Chi Square
IPR008967 p53-like transcription factor, DNA-binding IPR011989 ARM-like. 0.196485
IPR002117 p53 tumor antigen IPR011989 ARM-like. 0.0561701
IPR010991 p53, tetramerisation IPR011989 ARM-like. 0.0561701
IPR011615 P53_DNA_bd. IPR011989 ARM-like. 0.0561701
IPR012346 P53_RUNT_DNA_bd. IPR011989 ARM-like. 0.0561701

The background colour of the table refers to:

  • Blue Domain is only present in TP53
  • Yellow Domain is only present in KPNA2
  • Green Domain is present in both TP53 and KPNA2

 0.049
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: KPNA2

PTMResidueReference
Acetylation 22 PubMed, HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: KPNA2

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Nucleolus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and KPNA2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andKPNA2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and KPNA2 has 969 interactors of which there are 542 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for KPNA2-Interactor (?)
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.77 0.416
H2AFX H2AFX, H2AX: Histone H2A.x 4.27 0.032
HIST1H1E HIST1H1E, H1F4: Histone H1.4 2.08 0.090
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.033
HIST1H1B HIST1H1B, H1F5: Histone H1.5 1.26 0.073
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 0.0554
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.137
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.063
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.040
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.046
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.541 0.0354
SP100 N/A 0.525 0.0453
MCM3 MCM3: DNA replication licensing factor MCM3 0.515 0.040
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.503 0.063
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.503 0.063
SREBF2 N/A 0.475 0.027
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.0818
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.091
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.153
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.124
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.036
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.260
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.153
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.0446
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 0.124
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.124
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.111
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.111
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.111
CCNB1 Cyclin B1 0.385 0.040
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.318 0.075
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.304 0.188
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.284 0.067
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.304
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.040
POLA2 POLA2: DNA polymerase subunit alpha B 0.276 0.032
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.032
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.276 8.74
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.276 0.111
CENPA CENPA: Histone H3-like centromeric protein A 0.269 0.0446
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.027
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.091
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.260 0.124
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.057
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.253 0.070
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.245 0.063
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.241 0.040
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.241 0.032
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.241 0.040
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.032
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.233 0.225
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.054
RB1 RB1: Retinoblastoma-associated protein 0.210 0.027
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.153
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.057
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.027
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.067
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.067
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.139
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.0818
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.188 0.054
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.0818
MYB MYB: Myb proto-oncogene protein 0.176 0.075
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.162 0.096
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.155 0.096
ERF ERF: ETS domain-containing transcription factor ERF 0.155 0.057
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.146 0.111
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.146 0.032
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.146 0.111
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.145 0.029
ABCF1 N/A 0.144 0.070
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.087
MKI67 MKI67: Antigen KI-67 0.144 0.124
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.144 0.0425
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.036
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.036
ESPL1 N/A 0.144 0.087
PTMA N/A 0.144 0.027
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.141 0.063
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.141 0.046
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.141 0.063
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.141 0.233
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.141 0.063
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.140 0.033
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.139 0.051
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.139 0.0818
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.054
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.139 0.067
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.067
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.051
COPE COPE: Coatomer subunit epsilon 0.139 0.046
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.139 0.0818
RELA RELA, NFKB3: Transcription factor p65 0.139 0.113
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.029
CDC23 CDC23: Cell division cycle protein 23 homolog 0.137 0.063
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.137 0.139
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.137 59.30
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.036
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.132 0.124
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.132 0.251
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.0453
CDK4 CDK4: Cell division protein kinase 4 0.129 0.063
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.078
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.032
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.129 0.040
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.040
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.046
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.032
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.040
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.032
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 0.111
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.040
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.129 0.123
NUP153 N/A 0.129 0.032
SSB SSB: Lupus La protein 0.129 0.032
KIF11 N/A 0.129 0.040
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.040
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.063
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.129
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.066
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.032
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.132
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.118 0.0818
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.054
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.114 0.041
ETS1 ETS1, EWSR2: Protein C-ets-1 0.114 0.033
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.038
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.087
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.054
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.069
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.043
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.114 0.029
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 0.041
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.067
CSK CSK: Tyrosine-protein kinase CSK 0.112 0.038
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.112 0.038
HSP90AA1 Hsp89-alpha-delta-N 0.111 0.063
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.111 0.038
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.069
GTF2F2 N/A 0.0971 0.091
NFATC1 N/A 0.096 0.100
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.096 0.091
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.093 0.139
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.087 0.070
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.027
SET SET: Protein SET 0.087 0.036
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.0446
TCOF1 N/A 0.087 0.036
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.036
KIF23 N/A 0.087 0.124
DNMT1 DNMT1, AIM, DNMT: DNA 0.087 0.036
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.036
UNG N/A 0.087 0.0446
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.087 0.027
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.087 0.032
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.087 0.188
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.087 0.029
SOX4 SOX4: Transcription factor SOX-4 0.086 0.051
BRPF1 BRPF1, BR140: Peregrin 0.086 0.038
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.029
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.086 0.051
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.051
CREBBP CREBBP, CBP: CREB-binding protein 0.086 13.60
ATM ATM: Serine-protein kinase ATM 0.086 0.056
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.084 0.087
PPEF1 N/A 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
MAPK15 N/A 0.083 0.028
C20orf18 N/A 0.083 0.049
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.049
UHRF1 0.083 0.049
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.109
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.049
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.052
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.049
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.109
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.0818 0.046
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.114
H1FX H1FX: Histone H1x 0.080 0.100
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.032
FNBP1 N/A 0.078 0.086
CDK2 CDK2: Cell division protein kinase 2 0.078 0.063
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.181
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.040
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.032
LIG1 LIG1: DNA ligase 1 0.078 0.032
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.032
NOL1 N/A 0.078 0.032
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.032
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.078
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.046
CDK7 CDK7, MO15: Cell division protein kinase 7 0.078 0.078
MYBL2 MYBL2, BMYB: Myb-related protein B 0.078 0.0818
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.046
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.046
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.032
ETS2 ETS2: Protein C-ets-2 0.077 0.037
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.096
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.0453
ERG ERG: Transcriptional regulator ERG 0.077 0.0453
MDM4 MDM4, MDMX: Mdm4 protein 0.077 0.037
EEF2 EEF2, EF2: Elongation factor 2 0.075 0.114
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.044
SOX8 SOX8: Transcription factor SOX-8 0.075 0.044
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.075 0.044
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.044
GIT2 N/A 0.075 0.075
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.036
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.044
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.075 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.075
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.044
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.075 0.044
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.075 0.044
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.075 0.050
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.075
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.075 0.044
RNF20 0.075 0.044
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.074 0.032
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.074 0.070
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.071 0.090
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.071 0.073
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.070 0.032
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.070 0.074
WDR1 N/A 0.070 0.027
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.070 0.075
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.070
API5 N/A 0.070 0.0425
UBAP2 N/A 0.070 0.087
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.027
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.052
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.069 0.037
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.114
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.069 0.111
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.069 0.029
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.086
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.067 0.029
SYK SYK: Tyrosine-protein kinase SYK 0.067 0.029
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.066 0.126
HSPD1 0.066 0.063
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.066 0.257
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.066 0.078
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.066 0.063
VCP VCP: Transitional endoplasmic reticulum ATPase 0.066 0.118
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.066 0.045
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.066 0.063
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.066 0.063
CTPS CTPS: CTP synthase 1 0.066 0.078
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.066 0.046
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.066 0.078
HNRPK N/A 0.066 0.046
GPI GPI: Glucose-6-phosphate isomerase 0.066 0.046
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.066 0.078
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.066 0.156
MTHFD1 MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic 0.066 0.063
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.038
PPP1R8 N/A 0.063 0.0818
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.111
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.046
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.063
RPS6KB1 N/A 0.063 0.038
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.086
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.063
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.063 0.032
MYH9 MYH9: Myosin-9 0.063 0.041
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.139
HDAC2 HDAC2: Histone deacetylase 2 0.063 0.040
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.063 0.129
COPA COPA: Coatomer subunit alpha 0.063 0.029
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.063 0.038
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.051
WEE1 WEE1: Wee1-like protein kinase 0.063 0.063
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.063 0.038
CRLF3 N/A 0.063 0.0453
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.0453
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.062 0.098
RNF7 RNF7, RBX2, ROC2, SAG: RING-box protein 2 0.061 0.036
LYN LYN: Tyrosine-protein kinase Lyn 0.061 0.026
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.061 0.032
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.060 0.032
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.0453
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.057 0.026
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.026
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.057 0.031
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.056 0.041
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.056
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.069
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.056 0.051
ETV1 ETV1, ER81: ETS translocation variant 1 0.056 0.029
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.0554 0.086
STAT4 STAT4: Signal transducer and activator of transcription 4 0.055 0.032
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.055 0.037
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.054 0.046
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.055
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.049
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.049
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.0446
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.096
CHUK N/A 0.052 0.0425
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.057
TRRAP N/A 0.052 0.052
ARFGAP1 N/A 0.052 0.075
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.0425
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.032
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.0425
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.0425
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.051 0.038
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.225
RNF11 RNF11, CGI-123: RING finger protein 11 0.050 0.026
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.028
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.049 0.165
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.083
NASP NASP: Nuclear autoantigenic sperm protein 0.049 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.028
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.028
ELK1 ELK1: ETS domain-containing protein Elk-1 0.049 0.041
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.0308
SOX11 SOX11: Transcription factor SOX-11 0.049 0.029
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.047 0.098
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.025
SAPS3 N/A 0.046 0.029
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.046 0.029
SYMPK SYMPK, SPK: Symplekin 0.046 0.139
CUL5 CUL5, VACM1: Cullin-5 0.046 0.051
MDN1 MDN1, KIAA0301: Midasin 0.046 0.038
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.029
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.078
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.078
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.046 0.063
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.054
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.038
DIAPH1 Diaphanous 1 0.046 0.038
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.046 0.029
DOK1 DOK1: Docking protein 1 0.046 0.029
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.038
KLHDC4 N/A 0.046 0.038
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.046 0.029
GSK3B N/A 0.046 0.046
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.046 0.077
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0453 0.077
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.0446 0.0425
GTPBP4 GTPBP4, CRFG, NOG1: Nucleolar GTP-binding protein 1 0.0446 0.051
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.0446 0.087
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0446 0.070
TK1 TK1: Thymidine kinase, cytosolic 0.0446 0.070
FUBP1 N/A 0.0446 0.0425
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.044 0.033
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
VDR VDR, NR1I1: Vitamin D3 receptor 0.043 0.033
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.043 0.033
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.026
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.124
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.0425 0.057
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.077
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.026
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.026
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.026
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.032
COIL COIL, CLN80: Coilin 0.0425 0.0446
EXOC2 N/A 0.041 0.136
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.041 0.046
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.04 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 0.028
LCP1 LCP1, PLS2: Plastin-2 0.040 0.038
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.040 0.046
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.040 0.276
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.040 0.233
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.040 0.129
THOP1 THOP1: Thimet oligopeptidase 0.040 0.063
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.040 0.046
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.040 0.038
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.040 0.038
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.040 0.038
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.040 0.065
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.040 0.063
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.040 0.038
LPXN LPXN, LDLP: Leupaxin 0.040 0.038
XPO1 XPO1, CRM1: Exportin-1 0.040 0.372
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.039 0.026
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.039 0.0453
POLR2A POLR2A: Uncharacterized protein POLR2A 0.038 0.032
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.029
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.029
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.086
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.038 0.054
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.029
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.038 0.029
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.037 0.026
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.037 0.032
HD HD, IT15: Huntingtin 0.036 0.127
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.036 0.127
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.210
LIMS1 N/A 0.036 0.0425
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.036 0.032
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.036 0.041
IFI35 N/A 0.036 0.026
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.036 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.036 0.025
H1F0 H1F0, H1FV: Histone H1.0 0.035 0.030
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.035 0.058
FOXL2 FOXL2: Forkhead box protein L2 0.034 0.037
FN1 N/A 0.034 0.049
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.034 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.034 0.044
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.034
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.034 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.034 0.109
AXIN1 0.0333 0.083
YWHAG YWHAG: 14-3-3 protein gamma 0.0333 0.028
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.033 0.114
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.032
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.032
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.026
VIM VIM: Vimentin 0.032 0.0453
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.0453
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.026
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.026
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.032 0.114
FRG1 FRG1: Protein FRG1 0.032 0.046
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.032 0.063
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.038
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.032 0.038
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.038
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.032 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.032 0.087
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.032 0.046
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.029
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.038
ACTG1 ACTB: Actin, cytoplasmic 1 0.032 0.029
NRAS NRAS, HRAS1: GTPase NRas precursor 0.032 0.139
FLII FLII, FLIL: Protein flightless-1 homolog 0.032 0.071
PLD1 PLD1: Phospholipase D1 0.032 0.038
PPARBP N/A 0.032 0.046
RAB11A RAB11A, RAB11: Ras-related protein Rab-11A 0.032 0.045
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.032 0.046
CRKL CRKL: Crk-like protein 0.032 0.038
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.032 0.046
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.032 0.188
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.086
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.032 0.046
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.032 3.00
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.031 0.025
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.031 0.037
RFX1 RFX1: MHC class II regulatory factor RFX1 0.0308 0.029
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.0308 0.064
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.030 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.030 0.044
CSDA CSDA, DBPA: DNA-binding protein A 0.029 0.046
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.029
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.029 0.029
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.038
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.038
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.0308
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.029 0.029
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.083
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.052
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
RAB4A N/A 0.028 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.049
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.109
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.028 0.041
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.027 19.00
IPO9 IPO9, IMP9, HSPC273, KIAA1192, RANBP9: Importin-9 0.027 0.085
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.027 0.0425
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.027 0.032
MPG N/A 0.027 0.032
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.027 0.032
YWHAQ YWHAQ: 14-3-3 protein theta 0.027 0.070
CIITA CIITA, MHC2TA: MHC class II transactivator 0.027 0.032
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.032
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.026
PRKAA1 N/A 0.026 0.052
GRLF1 N/A 0.026 0.127
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.026
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.026
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.026
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.026 0.032
KRT18 KRT18: Uncharacterized protein KRT18 0.026 0.0453
IL9R IL9R: Interleukin-9 receptor precursor 0.025 0.0453
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.025 0.032
CIC CIC, KIAA0306: Protein capicua homolog 0.025 0.031
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.025
BCOR N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.047
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
PRKCB1 N/A 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.025
NIPBL N/A 0.025 0.075
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.044
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.050
ELMO1 N/A 0.025 0.075
GRK6 N/A 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.044
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.044
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
0.228
Total Score 10.00