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Evidence of Interaction Between TP53 and PPID

The interaction score between TP53 and PPID is 12.5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TP53 and PPID = 0.60

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology
OrganismTP53 OrthologuePPID OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly Q8IH92 0.16 Q9VT21 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains No domains were used in calculating likelihood of interaction 0.049
Post-translational Modifications

Protein: TP53

PTMResidueReference
Acetylation 305 PubMed, HPRD
Acetylation 320 PubMed, HPRD
Acetylation 370 PubMed, HPRD
Acetylation 372 PubMed, HPRD
Acetylation 373 PubMed, HPRD
Acetylation 381 PubMed, HPRD
Acetylation 382 PubMed, HPRD
Deacylation 382 PubMed, HPRD
Dephosphorylation 315 PubMed, HPRD
N6-acetyllysine 305 HPRD
N6-acetyllysine 373 HPRD
N6-acetyllysine 382 HPRD
Phosphorylation 6 PubMed, HPRD
Phosphorylation 9 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 18 PubMed, HPRD
Phosphorylation 20 PubMed, HPRD
Phosphorylation 33 PubMed, HPRD
Phosphorylation 37 PubMed, HPRD
Phosphorylation 46 PubMed, HPRD
Phosphorylation 55 PubMed, HPRD
Phosphorylation 81 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Phosphorylation 315 PubMed, HPRD
Phosphorylation 366 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphoserine 15 PubMed, HPRD
Phosphoserine 46 PubMed, HPRD
Phosphoserine 315 PubMed, HPRD
Phosphothreonine 18 PubMed, HPRD
Phosphothreonine 55 PubMed, HPRD
Proteolytic Cleavage 18 PubMed, HPRD
Proteolytic Cleavage 20 PubMed, HPRD
Proteolytic Cleavage 23 PubMed, HPRD
Sumoylation 386 PubMed, HPRD
Ubiquitination 351 PubMed, HPRD
Ubiquitination 357 PubMed, HPRD
Ubiquitination 370 PubMed, HPRD
Ubiquitination 372 PubMed, HPRD
Ubiquitination 373 PubMed, HPRD
Ubiquitination 381 PubMed, HPRD
Ubiquitination 382 PubMed, HPRD
Ubiquitination 386 PubMed, HPRD

Protein: PPID

PTMResidueReference
Acetylation 2 PubMed, HPRD
Localisation

Protein: TP53

LocalisationReference
ER HPRD
Nucleus HPRD
Mitochondrion HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: PPID

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TP53 and PPID that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TP53 andPPID. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TP53 has 1099 interactors and PPID has 949 interactors of which there are 590 common interactors.

Common InteractorName of Common InteractorScore for TP53-Interactor (?)Score for PPID-Interactor (?)
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.77 0.0425
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 2.54 0.032
HIST1H1E HIST1H1E, H1F4: Histone H1.4 2.08 0.032
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.58 0.051
PGR PGR, NR3C3: Progesterone receptor 1.00 0.029
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.964 4.27
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.902 0.033
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.822 0.040
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.704 0.129
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.704 3.51
PCNA PCNA: Proliferating cell nuclear antigen 0.704 0.032
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.651 0.153
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.541 0.041
SP100 N/A 0.525 0.036
MCM3 MCM3: DNA replication licensing factor MCM3 0.515 0.040
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.503 0.461
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.503 0.461
SREBF2 N/A 0.475 0.036
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.471 0.032
NBN NBN, NBS, NBS1, P95: Nibrin 0.430 0.253
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.430 0.0446
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.430 0.0446
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.430 0.0446
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.430 0.416
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.430 0.253
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.430 0.202
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.430 0.101
DDX21 DDX21: Nucleolar RNA helicase 2 0.430 0.0446
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.385 0.032
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.385 0.066
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.385 0.066
SP3 SP3: Transcription factor Sp3 0.347 0.040
SRF SRF: Serum response factor 0.344 0.111
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.318 0.091
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.304 0.129
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.304 0.156
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.290 0.032
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.276 0.040
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.276 0.040
POLA2 POLA2: DNA polymerase subunit alpha B 0.276 0.040
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.276 0.066
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.276 0.112
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.276 0.040
CENPA CENPA: Histone H3-like centromeric protein A 0.269 0.027
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.260 0.0446
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.260 0.074
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.260 0.101
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.260 0.036
EP300 N/A 0.254 0.032
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.253 0.515
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.245 0.372
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.241 0.040
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.241 0.032
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.241 0.032
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.233 0.040
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.233 0.185
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.241
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.233 0.078
YY1 YY1: Transcriptional repressor protein YY1 0.233 0.040
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.233 0.066
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.227 0.156
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.216 0.038
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.210 0.036
RB1 RB1: Retinoblastoma-associated protein 0.210 0.0446
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.210 0.036
ELF1 ELF1: ETS-related transcription factor Elf-1 0.210 0.0446
MATR3 MATR3, KIAA0723: Matrin-3 0.210 0.074
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.188 0.040
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.188 0.304
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.461
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.188 0.111
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.188 0.111
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.188 0.040
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.032
CXorf9 N/A 0.188 0.063
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.188 0.040
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.188 0.027
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.162 0.052
TP73 TP73, P73: Tumor protein p73 0.156 0.037
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.0446
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.155 0.070
XRCC1 XRCC1: DNA-repair protein XRCC1 0.155 0.101
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 0.148 0.093
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.146 0.066
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.146 0.040
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.146 0.040
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.145 0.188
ABCF1 N/A 0.144 0.087
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.087
MKI67 MKI67: Antigen KI-67 0.144 0.091
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.144 0.070
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.144 0.0446
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.144 0.074
ESPL1 N/A 0.144 0.052
PTMA N/A 0.144 0.074
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.141 0.046
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.141 0.078
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.141 0.078
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.141 0.078
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.141 0.129
SAT SAT1, SAT: Diamine acetyltransferase 1 0.140 0.032
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.139 0.067
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.139 0.071
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.139 0.067
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.139 0.040
COPE COPE: Coatomer subunit epsilon 0.139 0.139
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.139 0.040
KIAA1012 KIAA1012: Protein TRS85 homolog 0.139 0.146
CDC23 CDC23: Cell division cycle protein 23 homolog 0.137 0.146
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.137 0.036
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.132 0.0425
IRF3 IRF3: Interferon regulatory factor 3 0.132 0.027
CDK4 CDK4: Cell division protein kinase 4 0.129 0.063
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.129 0.078
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.040
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.129 0.032
HDAC3 HDAC3: Histone deacetylase 3 0.129 0.040
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.129 0.078
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.129 0.032
CBX3 CBX3: Chromobox protein homolog 3 0.129 0.066
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.129 0.066
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.129 0.066
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.032
NUP153 N/A 0.129 0.066
SSB SSB: Lupus La protein 0.129 0.066
KIF11 N/A 0.129 0.032
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.129 0.040
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.063
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.241
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.067
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.129 0.090
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.127 0.101
HIVEP1 N/A 0.127 0.036
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.124 0.046
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.118 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.114 0.139
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.071
FKBP4 FKBP4: FK506-binding protein 4 0.114 0.054
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.114 0.146
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.087
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.070
AIP AIP, XAP2: AH receptor-interacting protein 0.114 0.071
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.114 0.078
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.114 0.069
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.114 0.032
CSK CSK: Tyrosine-protein kinase CSK 0.112 0.078
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.112 0.078
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.111 0.139
HSP90AA1 Hsp89-alpha-delta-N 0.111 24.50
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.111 0.078
STAT6 STAT6: Signal transducer and activator of transcription 6 0.111 0.063
GTF2F2 N/A 0.0971 0.027
PSMD3 PSMD3: 26S proteasome non-ATPase regulatory subunit 3 0.0968 0.060
PSMD13 PSMD13: 26S proteasome non-ATPase regulatory subunit 13 0.0968 0.074
hfl-B5 PCID1, EIF3M, GA17, hfl-B5, hCG_27316: PCI domain containing 1 0.0968 0.123
NFATC1 N/A 0.096 0.027
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.096 0.032
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.096 0.027
PDK1 PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu 0.094 0.114
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.093 0.129
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.087 0.070
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.087 0.074
NCOA3 N/A 0.087 0.036
SET SET: Protein SET 0.087 0.074
RBM14 RBM14, SIP: RNA-binding protein 14 0.087 0.0446
TCOF1 N/A 0.087 0.0446
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.087 0.0446
IFI16 N/A 0.087 0.074
DNMT1 DNMT1, AIM, DNMT: DNA 0.087 0.036
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.087 0.036
TGIF2 TGIF2: Homeobox protein TGIF2 0.087 0.036
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.087 0.036
UNG N/A 0.087 0.032
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.087 0.078
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.087 0.038
BRPF1 BRPF1, BR140: Peregrin 0.086 0.046
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.078
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.086 0.032
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.086 0.054
ATM ATM: Serine-protein kinase ATM 0.086 0.046
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.084 0.070
PPEF1 N/A 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
MAPK15 N/A 0.083 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.052
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.028
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.0818 0.032
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.0818 0.054
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.0818 0.076
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0818 0.078
H1FX H1FX: Histone H1x 0.080 0.027
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.227
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.078 0.040
FNBP1 N/A 0.078 0.078
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.078 0.040
CDK2 CDK2: Cell division protein kinase 2 0.078 0.063
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.040
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.078 0.040
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.078 0.066
LIG1 LIG1: DNA ligase 1 0.078 0.032
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.078 0.066
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.078 0.040
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.078 0.040
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.078 0.066
NOL1 N/A 0.078 0.040
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.078 0.066
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.066
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.078 0.227
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.038
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.063
CDK7 CDK7, MO15: Cell division protein kinase 7 0.078 0.046
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.078 0.078
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.078 0.032
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.040
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.241
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.078 0.040
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.078 0.066
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.152
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.077 0.052
EEF2 EEF2, EF2: Elongation factor 2 0.075 0.063
GIT2 N/A 0.075 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.075 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.025
RNF20 0.075 0.044
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.074 0.032
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.074 0.063
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.071 0.051
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.070 0.087
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.070 0.036
WDR1 N/A 0.070 0.101
PLEK PLEK, P47: Pleckstrin 0.070 0.036
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.052
KIAA0853 N/A 0.070 0.0446
API5 N/A 0.070 0.087
UBAP2 N/A 0.070 0.052
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.070 0.027
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.0446
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.144
LIG4 LIG4: DNA ligase 4 0.069 0.054
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.029
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.069 0.052
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.067 0.188
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.067 0.063
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.067 0.029
SYK SYK: Tyrosine-protein kinase SYK 0.067 0.063
HSPD1 0.066 0.046
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.066 0.126
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.066 20.60
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.066 0.129
VCP VCP: Transitional endoplasmic reticulum ATPase 0.066 0.063
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.066 0.045
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.066 0.129
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.066 0.078
CTPS CTPS: CTP synthase 1 0.066 0.063
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.066 0.078
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.066 0.078
HNRPK N/A 0.066 0.129
GPI GPI: Glucose-6-phosphate isomerase 0.066 0.046
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.066 0.063
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.066 0.549
MTHFD1 MTHFD1, MTHFC, MTHFD: C-1-tetrahydrofolate synthase, cytoplasmic 0.066 0.063
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.063 0.090
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.063
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.063 0.066
PPP1R8 N/A 0.063 0.227
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.032
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.078
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.0446
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.063
RPS6KB1 N/A 0.063 0.078
SEC31L1 N/A 0.063 0.112
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.461
RBM7 0.063 0.032
WBSCR20A N/A 0.063 0.040
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.063
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.063 0.063
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.066
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.040
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.063 0.040
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.063 0.188
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.063 0.040
COPB2 COPB2: Coatomer subunit beta' 0.063 23.80
HDAC2 HDAC2: Histone deacetylase 2 0.063 8.55
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.063 0.038
COPA COPA: Coatomer subunit alpha 0.063 0.118
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.032
RAB8A RAB8A: RAB8A protein 0.063 0.032
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.063 0.129
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.040
WEE1 WEE1: Wee1-like protein kinase 0.063 0.029
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.063 0.129
CRLF3 N/A 0.063 0.036
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.061
SH3BP3 0.062 0.061
LYN LYN: Tyrosine-protein kinase Lyn 0.061 0.070
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.061 0.0425
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.061 0.0425
EIF3S10 EIF3S10, KIAA0139: Eukaryotic translation initiation factor 3 subunit 10 0.059 0.123
COPS2 N/A 0.059 0.123
COPS7B COPS7B, CSN7B: COP9 signalosome complex subunit 7b 0.059 0.123
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.057 0.026
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.057 0.032
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.056 0.040
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.038
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.086
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.0554 0.233
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.054 0.078
SOS1 SOS1: Son of sevenless homolog 1 0.054 0.032
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.054 0.041
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.052 0.036
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.052 0.191
CHUK N/A 0.052 0.087
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.036
TOP2B N/A 0.052 0.074
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.036
TRRAP N/A 0.052 0.052
ARFGAP1 N/A 0.052 0.036
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.070
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.036
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.0446
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.074
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.087
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.087
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.052 0.260
JAK1 0.051 0.063
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.051 0.069
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.051 0.046
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.051 0.071
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.083
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.049 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.049 0.052
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.028
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.083
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 0.069
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.049
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.048 0.057
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.048 0.037
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.047 0.025
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.046 0.156
SAPS3 N/A 0.046 0.063
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.046 0.063
SYMPK SYMPK, SPK: Symplekin 0.046 0.225
CUL5 CUL5, VACM1: Cullin-5 0.046 0.137
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.040
MDN1 MDN1, KIAA0301: Midasin 0.046 0.188
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.063
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.038
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.038
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.046 0.063
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.046 0.112
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.046 0.090
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.046
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.063
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.046 0.040
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.046 0.067
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.046 0.032
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.063
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.111
DIAPH1 Diaphanous 1 0.046 0.078
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.040
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.046 0.029
DOK1 DOK1: Docking protein 1 0.046 0.063
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.078
KLHDC4 N/A 0.046 0.078
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.046 0.063
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.046 0.046
CUL4B N/A 0.046 0.040
GSK3B N/A 0.046 0.063
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.046 0.078
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.0462 0.056
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.046 0.026
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.046 0.155
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.0453 0.032
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0453 0.026
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.0446 0.052
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.0446 0.0425
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0446 0.052
TK1 TK1: Thymidine kinase, cytosolic 0.0446 0.0425
FUBP1 N/A 0.0446 0.144
KLC2 KLC2: Kinesin light chain 2 0.044 0.0308
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
VDR VDR, NR1I1: Vitamin D3 receptor 0.043 0.0453
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.036
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.052
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.0425 0.027
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.0425 0.152
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0425 0.070
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.070
SMARCC2 N/A 0.0425 0.027
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.052
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.052
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.052
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.0425
RBM6 RBM6, DEF3: RNA-binding protein 6 0.0425 0.027
RGS14 N/A 0.0425 0.027
MARK2 N/A 0.0425 0.0425
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.041 0.046
EXOC2 N/A 0.041 0.063
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.041 0.029
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.041 0.054
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.04 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 0.028
LCP1 LCP1, PLS2: Plastin-2 0.040 0.078
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.040 0.078
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.040 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.040 0.078
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.040 0.078
THOP1 THOP1: Thimet oligopeptidase 0.040 0.063
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.040 0.063
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.040 0.063
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.040 0.078
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.040 0.046
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.040 0.038
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.040 0.078
LPXN LPXN, LDLP: Leupaxin 0.040 0.070
XPO1 XPO1, CRM1: Exportin-1 0.040 0.763
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.039 0.026
PPARG CREB3L2-PPARgamma 0.039 0.032
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.038 0.063
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.038
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.038 0.070
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.111
PSMD5 PSMD5, KIAA0072: 26S proteasome non-ATPase regulatory subunit 5 0.038 0.027
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.038 0.040
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.038 0.040
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.027
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.038 0.067
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.032
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.038
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.038 0.188
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.114
STK10 STK10: Uncharacterized protein STK10 0.038 0.063
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.029
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.038 0.038
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.038 0.0446
HD HD, IT15: Huntingtin 0.036 0.416
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.036 0.210
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.210
LIMS1 N/A 0.036 0.070
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.036 0.052
IFI35 N/A 0.036 0.070
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.036 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.036 0.025
COPS4 COPS4, CSN4: COP9 signalosome complex subunit 4 0.035 0.074
AXIN1 0.0333 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.0333 0.028
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.033 0.029
HCK N/A 0.033 0.038
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.033 0.038
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.052
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.0425
ID2 ID2: DNA-binding protein inhibitor ID-2 0.032 0.027
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.0425
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.0425
VIM VIM: Vimentin 0.032 0.046
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.036
GTF3C1 N/A 0.032 0.027
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.032
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.052
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.026
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.032 0.275
FRG1 FRG1: Protein FRG1 0.032 0.129
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.032 0.063
CLIC1 CLIC1, NCC27: Chloride intracellular channel protein 1 0.032 0.045
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.032 0.078
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.078
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.032 0.233
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.188
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.032 0.078
CASP3 CASP3, CPP32: Caspase-3 precursor 0.032 0.188
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.032 0.188
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.063
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.046
ACTG1 ACTB: Actin, cytoplasmic 1 0.032 0.063
NRAS NRAS, HRAS1: GTPase NRas precursor 0.032 0.188
FLII FLII, FLIL: Protein flightless-1 homolog 0.032 0.046
PLD1 PLD1: Phospholipase D1 0.032 0.029
PPARBP N/A 0.032 0.078
RAB11A RAB11A, RAB11: Ras-related protein Rab-11A 0.032 0.037
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.032 0.078
CRKL CRKL: Crk-like protein 0.032 0.078
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.032 0.063
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.032 0.078
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.032 0.233
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.032 0.114
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.032 0.046
CUL2 CUL2: Cullin-2 0.032 0.032
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.031 0.026
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.031 0.029
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.031 0.026
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.029 0.032
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.029 0.027
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.054
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.038
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.029 0.038
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.029 0.087
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.046
WDR44 WDR44: WD repeat-containing protein 44 0.029 0.032
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.046
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.029
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.029
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.029 0.029
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.049
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.025
SYTL4 Endocrine transmitter regulatory protein 0.028 0.049
NF2 NF2, SCH: Merlin 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.083
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
RAB4A N/A 0.028 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.028 0.029
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.027 0.029
IPO9 IPO9, IMP9, HSPC273, KIAA1192, RANBP9: Importin-9 0.027 0.140
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.027 0.096
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.027 0.052
MPG N/A 0.027 0.052
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.027 0.052
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.027 0.052
YWHAQ YWHAQ: 14-3-3 protein theta 0.027 0.087
CIITA CIITA, MHC2TA: MHC class II transactivator 0.027 0.052
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.027 0.032
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.032
PRKAA1 N/A 0.026 0.032
GRLF1 N/A 0.026 0.026
MEF2A N/A 0.026 0.091
NUP214 N/A 0.026 0.046
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.026
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.070
GABPB2 GABPB2, E4TF1B, GABPB, GABPB1: GA-binding protein beta chain 0.0255 0.0255
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 1.33
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.025
BCOR N/A 0.025 0.028
CAMKK1 N/A 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.036
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.036
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
PRKCB1 N/A 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.025
NIPBL N/A 0.025 0.148
ELMO1 N/A 0.025 0.075
GRK6 N/A 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.036
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.098
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
CAMK2A N/A 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.044
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.044
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
C11orf58 SMAP, C11orf58: Small acidic protein 0.025 0.025
NOLC1 NOLC1, KIAA0035: Nucleolar phosphoprotein p130 0.025 0.025
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.025 0.265
0.228
Total Score 12.5