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Evidence of Interaction Between MAPK1 and MAPK8IP1

The interaction score between MAPK1 and MAPK8IP1 is 11.60.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and MAPK8IP1 = -0.01

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismMAPK1 OrthologueMAPK8IP1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P39745 1 O16643 0.601
fly P40417 1 Q9W0K0 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and MAPK8IP1:
Domains in MAPK1Domains in MAPK8IP1
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001452 SH3
IPR006020 Phosphotyrosine interaction domain
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and MAPK8IP1 are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR011993 PH_type. 37.108
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR008271 Serine/threonine protein kinase, active site IPR001452 SH3 27.0049
IPR011009 Protein kinase-like IPR011993 PH_type. 21.3114
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR002290 Serine/threonine protein kinase IPR001452 SH3 11.0285
IPR003527 MAP kinase IPR006020 Phosphotyrosine interaction domain 1.95712
IPR008349 ERK1/2 MAP kinase IPR001452 SH3 1.37932
IPR003527 MAP kinase IPR001452 SH3 0.988997
IPR008271 Serine/threonine protein kinase, active site IPR011993 PH_type. 0.535834
IPR011009 Protein kinase-like IPR006020 Phosphotyrosine interaction domain 0.203907
IPR002290 Serine/threonine protein kinase IPR006020 Phosphotyrosine interaction domain 0.195004
IPR002290 Serine/threonine protein kinase IPR011993 PH_type. 0.0555974
IPR003527 MAP kinase IPR011993 PH_type. 0.0276008
IPR000719 Protein kinase IPR006020 Phosphotyrosine interaction domain 0.00379833
IPR008271 Serine/threonine protein kinase, active site IPR006020 Phosphotyrosine interaction domain 0.00100301

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in MAPK8IP1
  • Green Domain is present in both MAPK1 and MAPK8IP1

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: MAPK8IP1

PTMResidueReference
Phosphorylation 15 PubMed, HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 103 PubMed, HPRD
Phosphorylation 197 PubMed, HPRD
Phosphorylation 205 PubMed, HPRD
Phosphorylation 284 PubMed, HPRD
Phosphorylation 341 PubMed, HPRD
Phosphorylation 421 PubMed, HPRD
Phosphothreonine 103 PubMed, HPRD
Phosphothreonine 205 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: MAPK8IP1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and MAPK8IP1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andMAPK8IP1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and MAPK8IP1 has 1456 interactors of which there are 902 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for MAPK8IP1-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.225
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.040
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.044
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.075
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.075
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.075
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 12.60 0.027
CDK2 CDK2: Cell division protein kinase 2 6.80 0.078
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.099
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 2.53 0.137
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.035
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.099
GNAI2 Galphai2 protein 1.71 0.029
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 1.03 0.067
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.155
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.683 0.044
PLEK PLEK, P47: Pleckstrin 0.515 0.088
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.509 0.111
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.088
CRKL CRKL: Crk-like protein 0.461 0.099
JAK1 0.461 0.099
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.111
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.078
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.078
MSN MSN: Moesin 0.461 0.070
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.070
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.078
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 0.456 0.051
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 0.449 0.033
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.088
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.088
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 0.405 0.041
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.088
STK10 STK10: Uncharacterized protein STK10 0.385 0.078
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.040
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.078
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.070
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.078
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.099
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.078
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.078
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.078
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.050
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.078
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.078
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.099
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.099
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.171
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.040
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.098
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.110
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.098
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.110
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.088
DOK1 DOK1: Docking protein 1 0.275 0.078
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.099
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.078
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.099
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.078
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.099
HCK N/A 0.275 0.099
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.078
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.097
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.088
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.030
GAB2 N/A 0.251 0.152
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.110
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.110
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.123
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.035
WASPIP N/A 0.233 0.078
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.078
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.099
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.040
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.078
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.078
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.111
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.078
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.078
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.078
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.088
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.070
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.099
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.099
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.088
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.088
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.099
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.088
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.098
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.088
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.081
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.123
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.110
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.109
CXorf9 N/A 0.188 0.078
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.040
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.099
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.078
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.099
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.070
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.078
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.099
RPS6KB1 N/A 0.188 0.078
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.111
FNBP1 N/A 0.188 0.099
GMIP GMIP: GEM-interacting protein 0.188 0.040
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.031
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.028
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.136
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.088
PSD TYL: TYL protein 0.171 0.372
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.111
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.097
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.099
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.097
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.372
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PSCD2 N/A 0.165 0.165
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.028
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.165
BID BID: BH3-interacting domain death agonist 0.165 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.083
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.165
MAP2K5 N/A 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
ARFGAP1 N/A 0.155 0.056
HD HD, IT15: Huntingtin 0.155 0.055
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.191
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.088
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.109
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.065
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.098
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.123
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.110
SNCB SNCB: Beta-synuclein 0.152 0.163
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.110
ETS2 ETS2: Protein C-ets-2 0.152 0.098
CREB1 CREB1: cAMP response element-binding protein 0.148 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.047
CCNT2 CCNT2: Cyclin-T2 0.148 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.047
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.025
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.148
STAT3 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
ARHGEF7 N/A 0.148 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.075
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.078
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.078
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.099
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.099
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.070
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.078
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.088
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.275
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.099
ATM ATM: Serine-protein kinase ATM 0.139 0.099
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.070
CD2AP CD2AP: CD2-associated protein 0.139 0.078
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.099
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.099
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.078
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.372
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.461
RDX RDX: Radixin 0.136 0.136
VIL2 N/A 0.136 0.099
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.461
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.372
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.038
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.171
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.088
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.040
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.128
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.110
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.110
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.110
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.110
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.109
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.026
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.109
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.152
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.098
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.078
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.099
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.136
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.087
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.111
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.035
CDK5 CDK5: Cell division protein kinase 5 0.114 0.275
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.029
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.136
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.078
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.088
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.111
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.097
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.111
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.097
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.097
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.029
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.111
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 0.136
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.111 0.063
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.111
PLD2 PLD2: Phospholipase D2 0.111 0.097
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.152
BMX N/A 0.110 0.152
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.049
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.0971
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.191
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.191
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.251
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.109
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.171
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.032
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.109
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.044
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.111
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.275
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.097
PLD1 PLD1: Phospholipase D1 0.097 0.088
DAB1 DAB1: Disabled homolog 1 0.097 0.136
TST TST: Thiosulfate sulfurtransferase 0.097 0.0308
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.088
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.275
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.098
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.152
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.109
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.035
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.152
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.110
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.110
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.033
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.090 0.029
PTPRZ1 N/A 0.090 0.304
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.097
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.275
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.049
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.097
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.372
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.099
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.275
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.099
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.099
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.078
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.097
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.086 0.038
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.086 0.078
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.225
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.088
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.165
MAPKAPK5 N/A 0.083 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.165
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.165
MAPK15 N/A 0.083 0.165
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.165
HES6 HES6: Transcription cofactor HES-6 0.083 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.0818 0.065
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.171
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.0308
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.0308
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.123
PRKAA1 N/A 0.077 0.110
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.110
STK16 N/A 0.077 0.110
TSPYL2 TSPYL2, CDA1, HRIHFB2216, DENTT, TSPX: Testis-specific Y-encoded-like protein 2 0.077 0.052
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.098
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.152
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.110
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.098
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.075 0.033
ATP2B1 N/A 0.075 0.091
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.0727
MAX MAX: Protein max 0.075 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.148
GIT2 N/A 0.075 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.148
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.025
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
SNX3 N/A 0.075 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.148
CNN2 CNN2: Calponin-2 0.075 0.083
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.148
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.148
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.025
TSC2 TSC2, TSC4: Tuberin 0.075 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.148
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.148
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.148
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.065
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.073 0.040
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.037
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.081
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.038
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.069
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.099
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.069
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.035
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.049
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.048
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.171
CDK6 CDK6: Cell division protein kinase 6 0.069 0.088
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.088
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.275
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.171
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.088
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.049
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.088
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.097
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.097
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.088
CDK4 CDK4: Cell division protein kinase 4 0.069 0.099
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.099
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.097
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 0.058
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.090
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.040
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.035
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.028
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.040
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.038
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.038
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.111
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.088
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.070
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.035
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.031
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.063
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.086
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.144
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.123
COBL N/A 0.062 0.515
SPTAN1 N/A 0.062 0.852
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.098
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.055
GRLF1 N/A 0.062 0.152
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.073
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.113
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.057 0.072
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.029
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.057 0.058
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.072
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.033
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.372
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.099
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 0.275
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.372
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.088
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.171
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.097
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.088
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.056 0.046
WEE1 WEE1: Wee1-like protein kinase 0.056 0.078
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.056 0.026
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.043
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.047
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.109
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.026
TP73 TP73, P73: Tumor protein p73 0.055 0.152
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.044
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.031
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.028
RAB4A N/A 0.052 0.165
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.028
MECP2 MECP2: Methyl-CpG-binding protein 2 0.052 0.032
FUBP1 N/A 0.052 0.044
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.026
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.039
MEF2A N/A 0.052 0.032
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.0425
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
GRB10 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.065
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.044
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.136
CDKL5 N/A 0.049 0.123
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.109
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.109
EDA N/A 0.049 0.049
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.049 0.049
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.109
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.049 0.044
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.109
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.049 0.049
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
DYRK3 N/A 0.049 0.097
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.111
SORBS3 SORBS3, SCAM1: Vinexin 0.049 0.097
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.210
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.048 0.087
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.075
SOX8 SOX8: Transcription factor SOX-8 0.047 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.148
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.025
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.099
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.046 0.088
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.035
DLG1 N/A 0.046 0.038
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.040
XPO1 XPO1, CRM1: Exportin-1 0.046 0.050
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.029
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.099
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.035
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.0453 0.029
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.065
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.0453 0.081
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.0727
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.0453 0.029
MYO3A MYO3A: Myosin IIIA 0.044 0.136
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.171
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.171
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.136
CTTN CTTN, EMS1: Src substrate cortactin 0.044 0.191
CNN3 CNN3: Calponin-3 0.044 0.096
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.225
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.088
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.171
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.171
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.098
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.098
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.188
SH3BP3 0.0425 0.026
PDE4A N/A 0.0425 0.052
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.035
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.031
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.046
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.073
GLRB GLRB: Glycine receptor subunit beta precursor 0.041 0.066
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.058
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.227
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.052
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.052
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.136
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.111
RAB8A RAB8A: RAB8A protein 0.039 0.026
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.039 0.046
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.039 0.070
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.087
MYH9 MYH9: Myosin-9 0.038 0.035
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.038 0.044
GMFB GMFB: Glia maturation factor beta 0.038 0.046
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.028
APC N/A 0.038 0.063
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.050
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.038 0.029
RNF11 RNF11, CGI-123: RING finger protein 11 0.038 0.063
DYNC1I2 N/A 0.038 0.038
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.040
MDN1 MDN1, KIAA0301: Midasin 0.038 0.088
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.078
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.089
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.225
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.040
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.033
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.065
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.0727
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.065
GHR GHR: Growth hormone receptor precursor 0.037 0.065
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.072
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.032
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.072
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.0727
RAP1GA1 N/A 0.037 0.027
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.052
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.058
CRLF3 N/A 0.036 0.052
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.058
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.058
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.0727
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.052
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.036 0.072
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.052
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.052
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.036 0.058
RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 0.0354 0.037
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.034 0.032
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.034
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.0338 0.0782
MAL2 MAL2: Protein MAL2 0.034 0.034
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.111
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.033 0.041
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.0818
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.0818
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.029
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.058
RHO RHO, OPN2: Rhodopsin 0.033 0.037
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.029
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.081
PRLR PRLR: Prolactin receptor precursor 0.033 0.072
F3 F3: Tissue factor precursor 0.032 0.037
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.032 0.032
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.081
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.072
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.100
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.037
ITGB4 N/A 0.032 0.072
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.561
CP110 N/A 0.032 0.052
MAP2K5 N/A 0.032 0.026
MAPK8IP3 MAPK8IP3, JIP3, KIAA1066: C-jun-amino-terminal kinase-interacting protein 3 0.032 0.070
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.049
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.163
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.034
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.065
RYR2 RYR2: Ryanodine receptor 2 0.031 0.063
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.099
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.152
SOX11 SOX11: Transcription factor SOX-11 0.0308 0.029
PHLPP PHLPP, KIAA0606, PLEKHE1, SCOP: PH domain leucine-rich repeat-containing protein 0.0308 0.067
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.047
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.038
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.030 0.030
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.064
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.064
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.181
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.037
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.072
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.029 0.065
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.100
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.058
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.090
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.038
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.029
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.038
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.029 0.063
LIG1 LIG1: DNA ligase 1 0.029 0.078
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.029 0.188
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.139
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.088
AHCYL1 AHCYL1, DCAL, XPVKONA: Putative adenosylhomocysteinase 2 0.029 0.063
PMM1 PMM1, PMMH22: Phosphomannomutase 1 0.029 0.038
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.078
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
IRF7 N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.052
WDR54 N/A 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
C20orf18 N/A 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.028
CABLES1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
SNRPB N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
ZNF265 N/A 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.083
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.028
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
PTPN7 N/A 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
HDAC8 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.083
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.028
DUSP15 N/A 0.028 0.028
AXIN1 0.028 0.028
MATK 0.028 0.028
UHRF1 0.028 0.028
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
PHLDB2 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.052
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.028
PPEF1 N/A 0.028 0.028
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
KIF1B N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
CORO6 N/A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.028
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.028 0.155
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.097
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0277 0.032
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
FAM43A N/A 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
OSBPL9 N/A 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
PARP9 N/A 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
PSD3 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
LILRB1 N/A 0.027 0.0727
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.0727
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.058
ITGAE ITGAE: Integrin alpha-E precursor 0.027 0.0727
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.032
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.073
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.064
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.073
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.041
PPARGC1A PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1: Peroxisome proliferator-activated receptor 0.026 0.026
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.110
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.056
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.044
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.152
DBN1 DBN1, D0S117E: Drebrin 0.026 0.026
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.087
EPN1 N/A 0.026 0.026
RGS4 RGS4: Regulator of G-protein signaling 4 0.026 0.070
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.049
DCAMKL1 DCLK1, DCAMKL1, DCDC3A, KIAA0369: Serine/threonine-protein kinase DCLK1 0.026 0.144
KIF23 N/A 0.026 0.056
MT3 MT3: Metallothionein-3 0.026 0.174
CEP170 CEP170, FAM68A, KAB, KIAA0470: Centrosomal protein of 170 kDa 0.026 0.0425
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0253 0.0955
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.041
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.075
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.148
BCR N/A 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.047
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.075
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
MYO18A 0.025 0.047
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
EPN2 N/A 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.047
TCEA1 N/A 0.025 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
HTATIP N/A 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
SEC13L1 N/A 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
C20orf77 N/A 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
BRD4 N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.047
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.148
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.025
GRK6 N/A 0.025 0.025
NUP98 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.148
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RNF20 0.025 0.025
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.025
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
SON 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.050
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.148
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
ATXN2L N/A 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.025
RAC1 N/A 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.025
FLJ23436 N/A 0.025 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
NIPBL N/A 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.047
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
NES N/A 0.025 0.028
KCTD1 0.025 0.025
HDAC7A N/A 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
DIDO1 N/A 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.148
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
0.299
Total Score 11.60