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Evidence of Interaction Between MAPK1 and LNK

The interaction score between MAPK1 and LNK is 19.70.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology N/A N/A
Domains Domains present in MAPK1 and LNK:
Domains in MAPK1Domains in LNK
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001849 Pleckstrin-like
IPR000980 SH2 motif
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and LNK are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR000719 Protein kinase IPR001849 Pleckstrin-like 66.4046
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR011009 Protein kinase-like IPR001849 Pleckstrin-like 42.4143
IPR008271 Serine/threonine protein kinase, active site IPR000980 SH2 motif 41.4368
IPR000719 Protein kinase IPR011993 PH_type. 37.108
IPR011009 Protein kinase-like IPR011993 PH_type. 21.3114
IPR002290 Serine/threonine protein kinase IPR000980 SH2 motif 18.5445
IPR003527 MAP kinase IPR000980 SH2 motif 3.65309
IPR002290 Serine/threonine protein kinase IPR001849 Pleckstrin-like 1.96919
IPR008349 ERK1/2 MAP kinase IPR000980 SH2 motif 0.969135
IPR008271 Serine/threonine protein kinase, active site IPR011993 PH_type. 0.535834
IPR008271 Serine/threonine protein kinase, active site IPR001849 Pleckstrin-like 0.123565
IPR002290 Serine/threonine protein kinase IPR011993 PH_type. 0.0555974
IPR003527 MAP kinase IPR011993 PH_type. 0.0276008
IPR003527 MAP kinase IPR001849 Pleckstrin-like 0.00368055

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in LNK
  • Green Domain is present in both MAPK1 and LNK

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: LNK

PTMResidueReference
Phosphorylation 273 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: LNK

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and LNK that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andLNK. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and LNK has 1743 interactors of which there are 979 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for LNK-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.165
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.109
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.109
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.165
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.165
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.109
DIAPH1 Diaphanous 1 20.60 0.028
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 12.60 0.027
DUSP8 DUSP8, VH5: Dual specificity protein phosphatase 8 11.60 0.027
CDK2 CDK2: Cell division protein kinase 2 6.80 0.165
HSPD1 6.11 0.028
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.049
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.028
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.028
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.165
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.165
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 1.42 0.052
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 1.03 0.04
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.109
PLEK PLEK, P47: Pleckstrin 0.515 0.109
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.165
CRKL CRKL: Crk-like protein 0.461 0.165
JAK1 0.461 1.30
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.165
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.165
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.165
MSN MSN: Moesin 0.461 0.165
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 1.30
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.165
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 0.456 0.04
DUSP7 DUSP7, PYST2: Dual specificity protein phosphatase 7 0.440 0.027
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.165
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.109
STYXL1 STYXL1, DUSP24, MKSTYX: Serine/threonine/tyrosine-interacting-like protein 1 0.402 0.027
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.165
STK10 STK10: Uncharacterized protein STK10 0.385 0.165
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.083
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.109
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.165
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.165
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.165
LYN LYN: Tyrosine-protein kinase Lyn 0.372 1.30
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.165
CSK CSK: Tyrosine-protein kinase CSK 0.372 1.30
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.083
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 1.30
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.028
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.165
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 1.30
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 1.30
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.165
GTPBP5 GTPBP5, OBGH1: GTP-binding protein 5 0.354 0.027
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.083
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.165
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.165
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.165
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.165
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.165
CDK3 CDK3: Cell division protein kinase 3 0.285 0.027
DOK1 DOK1: Docking protein 1 0.275 0.165
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 1.30
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.109
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.165
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.165
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 1.30
HCK N/A 0.275 1.30
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.028
SYK SYK: Tyrosine-protein kinase SYK 0.275 1.30
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.165
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.028
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.165
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.056
GAB2 N/A 0.251 0.165
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 1.30
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.165
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.165
EPM2A EPM2A: Laforin 0.244 0.027
RNGTT RNGTT, CAP1A: mRNA-capping enzyme 0.237 0.027
DUSP9 DUSP9, MKP4: Dual specificity protein phosphatase 9 0.237 0.027
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.049
WASPIP N/A 0.233 0.165
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.165
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.165
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.083
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.165
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.165
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.165
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.165
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.165
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.028
SH3BP5 N/A 0.225 0.028
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.165
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.109
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.165
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.165
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.165
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.165
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.109
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.109
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.165
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.165
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.052
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.165
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.0333
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.165
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.165
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.109
CXorf9 N/A 0.188 0.165
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.052
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.165
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.165
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.165
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.109
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.165
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.165
RPS6KB1 N/A 0.188 0.165
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.165
FNBP1 N/A 0.188 0.165
GMIP GMIP: GEM-interacting protein 0.188 0.083
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.028
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.165
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.165
PSD TYL: TYL protein 0.171 0.165
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.165
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.165
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.165
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.165
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.109
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PSCD2 N/A 0.165 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.083
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 1.30
MAP2K5 N/A 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
ARFGAP1 N/A 0.155 0.049
HD HD, IT15: Huntingtin 0.155 0.052
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.165
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.028
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.165
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.165
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.109
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.165
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.165
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 1.30
SNCB SNCB: Beta-synuclein 0.152 0.052
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 1.30
ETS2 ETS2: Protein C-ets-2 0.152 0.109
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.028
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.165
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.165
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.165
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 1.30
STAT3 0.148 0.165
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.165
ELMO1 N/A 0.148 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.165
ARHGEF7 N/A 0.148 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.165
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.165
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.109
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 1.30
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.083
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.028
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.165
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.165
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.109
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.165
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.028
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.165
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.165
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.165
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.165
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.165
ATM ATM: Serine-protein kinase ATM 0.139 0.165
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.028
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.165
CD2AP CD2AP: CD2-associated protein 0.139 0.165
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.165
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.083
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.165
FYN N/A 0.137 0.265
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.165
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.165
RDX RDX: Radixin 0.136 0.165
VIL2 N/A 0.136 0.165
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.165
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.165
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.028
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.109
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.165
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.028
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.083
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.0688
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.165
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.165
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.165
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.028
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.165
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.165
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.028
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.109
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.165
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.165
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.165
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.028
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.165
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.165
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.165
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.028
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.165
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.165
CDK5 CDK5: Cell division protein kinase 5 0.114 0.165
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.165
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.165
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.165
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.028
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.028
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.165
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.165
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.04
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.165
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 1.30
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.165
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.165
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 0.165
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.111 0.028
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 1.30
PLD2 PLD2: Phospholipase D2 0.111 0.165
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 1.30
BMX N/A 0.110 1.30
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.052
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.165
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.165
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.109
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.109
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.165
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 1.30
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.165
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.049
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.109
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 1.30
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.165
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.109
PLD1 PLD1: Phospholipase D1 0.097 0.165
DAB1 DAB1: Disabled homolog 1 0.097 0.165
TST TST: Thiosulfate sulfurtransferase 0.097 0.028
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.165
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.165
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.165
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.165
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.028
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.028
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.165
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.109
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.052
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.165
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.165
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.165
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.109
CD44 N/A 0.091 0.049
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.090 0.049
PTPRZ1 N/A 0.090 0.109
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 1.30
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.165
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.028
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.028
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.109
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.165
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.165
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.165
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.165
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.165
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.165
CTPS CTPS: CTP synthase 1 0.086 0.028
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.165
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.165
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.086 0.028
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.165
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.052
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.165
MAPKAPK5 N/A 0.083 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.052
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.165
MAPK15 N/A 0.083 0.165
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.165
HES6 HES6: Transcription cofactor HES-6 0.083 0.049
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.083 0.265
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.083 0.027
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.0818 0.049
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.049
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.165
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.028
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.052
LCP1 LCP1, PLS2: Plastin-2 0.078 0.083
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.028
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.028
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.028
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.028
HNRPK N/A 0.078 0.028
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.028
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.028
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 0.028
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.028
UBE4A N/A 0.078 0.028
KLHDC4 N/A 0.078 0.028
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.052
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.052
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.165
PRKAA1 N/A 0.077 0.165
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.165
STK16 N/A 0.077 0.165
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.165
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.028
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.165
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.165
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.165
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.075 0.04
ATP2B1 N/A 0.075 0.049
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.109
FADD FADD, MORT1: Protein FADD 0.075 0.04
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.165
GIT2 N/A 0.075 0.083
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.165
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.109
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.109
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.083
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.165
SNX3 N/A 0.075 0.052
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.165
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.083
CNN2 CNN2: Calponin-2 0.075 0.165
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.165
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.109
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.165
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.165
TSC2 TSC2, TSC4: Tuberin 0.075 0.028
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 1.30
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.165
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.165
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.165
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.165
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.165
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.165
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.083
PLCB2 0.074 0.027
RIN3 N/A 0.074 0.027
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.109
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.056
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.109
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.109
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.028
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.165
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.109
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.028
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.083
ABCF1 N/A 0.070 0.028
CASP8 N/A 0.070 0.028
IFI35 N/A 0.070 0.028
MARK2 N/A 0.070 0.028
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.052
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.165
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.165
CDK6 CDK6: Cell division protein kinase 6 0.069 0.165
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.165
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.165
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.165
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.165
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.083
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.165
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.165
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.165
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.165
CDK4 CDK4: Cell division protein kinase 4 0.069 0.165
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.028
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.165
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.165
SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 0.067 0.027
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 0.980
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.109
GSK3B N/A 0.063 0.028
COPA COPA: Coatomer subunit alpha 0.063 0.028
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.083
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.083
PTPN11 N/A 0.063 0.028
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.04
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.028
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.028
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.028
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.063 0.028
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.083
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.028
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.028
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.028
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.083
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.052
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.028
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.165
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.165
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.028
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.083
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.028
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.052
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.028
EXOC2 N/A 0.063 0.028
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.052
PPARBP N/A 0.063 0.028
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.083
FRG1 FRG1: Protein FRG1 0.063 0.028
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.028
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.052
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.165
COBL N/A 0.062 0.165
SPTAN1 N/A 0.062 0.165
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.109
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.109
GRLF1 N/A 0.062 0.165
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.04
MTMR6 MTMR6: Myotubularin-related protein 6 0.060 0.027
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.060 0.027
CERK CERK, KIAA1646: Ceramide kinase 0.060 0.027
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.109
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.109
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.057 0.049
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.049
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.109
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.0688
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.165
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.028
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.028
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.165
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 1.30
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.165
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.165
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.165
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.165
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.165
WEE1 WEE1: Wee1-like protein kinase 0.056 0.165
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.052
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.051
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.165
TP73 TP73, P73: Tumor protein p73 0.055 0.109
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.04
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.109
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.051
RAB4A N/A 0.052 0.109
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.04
DNM2 N/A 0.052 0.028
CHUK N/A 0.052 0.028
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.028
FUBP1 N/A 0.052 0.083
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.028
MVP MVP, LRP: Major vault protein 0.052 0.028
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.052
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.028
LIMS1 N/A 0.052 0.028
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.028
API5 N/A 0.052 0.028
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.028
AHNAK AHNAK: AHNAK protein 0.052 0.028
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.028
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.028
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.083
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.028
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
GRB10 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PTPRA N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.109
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.051 0.049
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.056
HES1 HES1, HL, HRY: Transcription factor HES-1 0.050 0.049
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.165
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.165
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.050 0.027
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.050 0.027
RANBP3 N/A 0.050 0.027
NCF2 NCF2: Neutrophil cytosol factor 2 0.050 0.027
ASB8 ASB8, PP14212: Ankyrin repeat and SOCS box protein 8 0.050 0.027
CDKL5 N/A 0.049 0.165
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.049 0.028
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.165
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.049
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.109
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.980
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.109
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.049 0.044
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
DYRK3 N/A 0.049 0.165
AQP1 AQP1, CHIP28: Aquaporin-1 0.049 0.028
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.165
AQP2 AQP2: Aquaporin-2 0.049 0.028
SORBS3 SORBS3, SCAM1: Vinexin 0.049 0.165
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.109
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.028
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.048 0.028
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.028
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.028
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.109
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.165
EVL N/A 0.046 0.028
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.028
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.165
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.028
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.028
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.083
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.028
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.028
BRPF1 BRPF1, BR140: Peregrin 0.046 0.028
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.028
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.028
DLG1 N/A 0.046 0.028
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.028
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.028
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.046 0.028
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.028
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.028
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.028
XPO1 XPO1, CRM1: Exportin-1 0.046 0.083
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.028
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.028
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.028
LPXN LPXN, LDLP: Leupaxin 0.046 0.028
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.028
COPE COPE: Coatomer subunit epsilon 0.046 0.028
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.165
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.028
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.028
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.028
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.083
SAPS3 N/A 0.046 0.028
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.028
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.028
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.028
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.028
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.109
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.051
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.051
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.051
EPB41 EPB41, E41P: Protein 4.1 0.046 0.051
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.056
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.0453 0.049
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.109
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.0453 0.109
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.109
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.0453 0.04
PIP3-E N/A 0.044 0.027
MTMR1 MTMR1: Myotubularin-related protein 1 0.044 0.027
ARHGAP26 ARHGAP26, GRAF, KIAA0621, OPHN1L: Rho GTPase-activating protein 26 0.044 0.027
CENTB1 CENTB1, KIAA0050: Centaurin-beta 1 0.044 0.027
MYO3A MYO3A: Myosin IIIA 0.044 0.165
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.165
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.165
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.165
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.165
CTTN CTTN, EMS1: Src substrate cortactin 0.044 0.165
CNN3 CNN3: Calponin-3 0.044 0.165
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.165
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.165
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.165
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.165
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.109
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.049
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.049
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.109
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.049
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.109
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.109
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.028
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.028
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.028
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.028
DAPP1 N/A 0.0425 0.028
MPG N/A 0.0425 0.028
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.052
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.028
PDE4A N/A 0.0425 0.028
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.028
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.052
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.051
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.0688
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.980
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.980
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.049
LDLRAP1 LDLRAP1, ARH: Low density lipoprotein receptor adapter protein 1 0.041 0.027
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.041 0.027
PLEKHA1 PLEKHA1, TAPP1: Pleckstrin homology domain-containing family A member 1 0.041 0.027
CENTA2 CENTA2: Centaurin-alpha 2 0.041 0.027
MYLIP MYLIP, BZF1, BM-023, PP5242: E3 ubiquitin-protein ligase MYLIP 0.041 0.027
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.109
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.109
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.165
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.165
RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 0.039 0.056
RAB8A RAB8A: RAB8A protein 0.039 0.044
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.039 0.056
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.039 0.028
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.028
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.028
MYH9 MYH9: Myosin-9 0.038 0.049
RP2 RP2: Protein XRP2 0.038 0.028
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.028
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.028
GMFB GMFB: Glia maturation factor beta 0.038 0.028
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.028
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 0.028
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.049
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.028
APC N/A 0.038 0.028
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.028
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.028
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.083
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.028
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.028
DYNC1I2 N/A 0.038 0.028
CFL1 CFL1, CFL: Cofilin-1 0.038 0.028
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.028
CAT CAT: Catalase 0.038 0.028
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.028
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.028
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.028
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.028
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.028
CHP CHP: Calcium-binding protein p22 0.038 0.052
MDN1 MDN1, KIAA0301: Midasin 0.038 0.083
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.165
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.028
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.028
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.028
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.028
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.165
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.028
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.165
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.028
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.109
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.109
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.109
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.049
GHR GHR: Growth hormone receptor precursor 0.037 0.109
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.109
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.109
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.109
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.109
RASA4 RASA4, CAPRI, GAPL, KIAA0538: Ras GTPase-activating protein 4 0.036 0.027
ARAF ARAF, ARAF1, PKS, PKS2: A-Raf proto-oncogene serine/threonine-protein kinase 0.036 0.027
MTMR3 MTMR3, KIAA0371, ZFYVE10: Myotubularin-related protein 3 0.036 0.027
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.036 0.027
PTPN9 0.036 0.027
RASA2 RASA2, GAP1M, RASGAP: Ras GTPase-activating protein 2 0.036 0.027
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.109
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.109
CRLF3 N/A 0.036 0.109
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.109
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.109
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.109
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.109
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.036 0.049
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.109
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.109
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.036 0.049
RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 0.0354 0.056
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.04
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.028
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.034 0.028
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.051
MAL2 MAL2: Protein MAL2 0.034 0.034
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.049
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.033 0.049
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.049
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.049
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.049
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.109
RHO RHO, OPN2: Rhodopsin 0.033 0.049
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.049
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.109
PRLR PRLR: Prolactin receptor precursor 0.033 0.109
F3 F3: Tissue factor precursor 0.032 0.109
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.032 0.049
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.049
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.109
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.049
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.049
ITGB4 N/A 0.032 0.109
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.109
CP110 N/A 0.032 0.028
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.052
ZYX ZYX: Zyxin 0.032 0.028
MAP2K5 N/A 0.032 0.028
UBAP2 N/A 0.032 0.028
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.083
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.052
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.028
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.032 0.028
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.028
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.109
RYR2 RYR2: Ryanodine receptor 2 0.031 0.034
DES DES: Desmin 0.031 0.028
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.165
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.165
PTPN7 PTPN7: Tyrosine-protein phosphatase non-receptor type 7 0.0308 0.027
PHLPP PHLPP, KIAA0606, PLEKHE1, SCOP: PH domain leucine-rich repeat-containing protein 0.0308 0.027
DIP13B APPL2, DIP13B: DCC-interacting protein 13-beta 0.0308 0.027
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.030 0.034
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.980
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.109
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.109
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.049
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.109
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.029 0.049
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.049
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.980
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.109
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.028
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.052
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.029 0.028
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.028
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.028
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.052
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.028
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.028
THOP1 THOP1: Thimet oligopeptidase 0.029 0.028
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.029 0.028
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.029 0.028
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.028
SYMPK SYMPK, SPK: Symplekin 0.029 0.028
LIG1 LIG1: DNA ligase 1 0.029 0.049
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.028
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.029 0.083
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.028
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.083
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.029 0.028
IMPAD1 N/A 0.029 0.028
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.028
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.028
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.028
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.028
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.028
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 0.029 0.028
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.028
AHCYL1 AHCYL1, DCAL, XPVKONA: Putative adenosylhomocysteinase 2 0.029 0.028
PMM1 PMM1, PMMH22: Phosphomannomutase 1 0.029 0.028
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.028
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.028
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.028
KIAA0690 N/A 0.029 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.083
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.049
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.052
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.052
AXIN1 0.028 0.028
MATK 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.052
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PPEF1 N/A 0.028 0.052
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.028 0.0688
KRAS N/A 0.0278 0.027
FOXL2 FOXL2: Forkhead box protein L2 0.028 0.04
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.165
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0277 0.028
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.028 0.027
VAV3 VAV3: Protein vav-3 0.028 0.027
MTM1 MTM1, CG2: Myotubularin 0.028 0.027
RANBP1 RANBP1: Ran-specific GTPase-activating protein 0.028 0.027
APBB1IP APBB1IP, PREL1, RARP1, RIAM: Amyloid beta A4 precursor protein-binding family B 0.028 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
FAM43A N/A 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.265
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
PSD3 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
LILRB1 N/A 0.027 0.109
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.109
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.109
ITGAE ITGAE: Integrin alpha-E precursor 0.027 0.049
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.049
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.109
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.980
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.980
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.049
TRRAP N/A 0.026 0.028
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.028
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.028
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.028
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.052
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.052
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 1.30
DBN1 DBN1, D0S117E: Drebrin 0.026 0.028
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.052
EPN1 N/A 0.026 0.028
RGS4 RGS4: Regulator of G-protein signaling 4 0.026 0.028
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.052
DCAMKL1 DCLK1, DCAMKL1, DCDC3A, KIAA0369: Serine/threonine-protein kinase DCLK1 0.026 0.028
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.028
IREB2 IREB2: Iron-responsive element-binding protein 2 0.026 0.028
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.028
ESPL1 N/A 0.026 0.028
MT3 MT3: Metallothionein-3 0.026 0.056
OSTF1 N/A 0.0255 0.027
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0253 0.051
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.0688
LMO6 LMO6: LIM domain only protein 6 0.025 0.028
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.083
RAD50 RAD50: DNA repair protein RAD50 0.025 0.028
SCRIB N/A 0.025 0.028
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.028
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.028
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.028
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.165
BCR N/A 0.025 0.028
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.028
GSN GSN: Gelsolin precursor 0.025 0.028
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.083
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.028
MYO18A 0.025 0.028
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.028
EPN2 N/A 0.025 0.028
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.028
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.028
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.028
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.028
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.028
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.028
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.04
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.028
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.083
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.028
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.028
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.028
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.028
BCOR N/A 0.025 0.028
MAP2K3 N/A 0.025 0.028
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.109
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.028
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.028
GRK6 N/A 0.025 0.028
CASP7 N/A 0.025 0.028
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.165
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.028
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.044
PRKCB1 N/A 0.025 0.028
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.028
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.028
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.052
RAC1 N/A 0.025 0.028
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.028
NIPBL N/A 0.025 0.028
DBNL N/A 0.025 0.028
CAMK2A N/A 0.025 0.028
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.028
CFL2 CFL2: Cofilin-2 0.025 0.028
SVIL SVIL: Supervillin 0.025 0.028
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.028
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.028
CAMKK1 N/A 0.025 0.028
ADK ADK: Adenosine kinase 0.025 0.028
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.165
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.028
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.028
0.299
Total Score 19.70