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Evidence of Interaction Between MAPK1 and NRAS

The interaction score between MAPK1 and NRAS is 14.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and NRAS = 0.52

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 6.27E-3
Orthology
OrganismMAPK1 OrthologueNRAS OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P39745 1 P22981 0.47
fly P40417 1 P08646 0.424

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and NRAS:
Domains in MAPK1Domains in NRAS
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001806 Ras GTPase superfamily
IPR003577 Ras small GTPase, Ras type
IPR005225 Small GTP-binding protein domain
IPR013753 Ras

The Chi square scores for co-occurrence of domains that are present in MAPK1 and NRAS are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR005225 Small GTP-binding protein domain 22.2209
IPR000719 Protein kinase IPR001806 Ras GTPase superfamily 21.6553
IPR011009 Protein kinase-like IPR005225 Small GTP-binding protein domain 8.50423
IPR000719 Protein kinase IPR013753 Ras 8.28186
IPR011009 Protein kinase-like IPR001806 Ras GTPase superfamily 8.19786
IPR002290 Serine/threonine protein kinase IPR005225 Small GTP-binding protein domain 4.76786
IPR002290 Serine/threonine protein kinase IPR001806 Ras GTPase superfamily 4.59383
IPR008271 Serine/threonine protein kinase, active site IPR005225 Small GTP-binding protein domain 3.57389
IPR008271 Serine/threonine protein kinase, active site IPR001806 Ras GTPase superfamily 3.38853
IPR011009 Protein kinase-like IPR013753 Ras 3.10535
IPR000719 Protein kinase IPR003577 Ras small GTPase, Ras type 1.66818
IPR002290 Serine/threonine protein kinase IPR013753 Ras 0.677359
IPR008271 Serine/threonine protein kinase, active site IPR003577 Ras small GTPase, Ras type 0.439442
IPR008271 Serine/threonine protein kinase, active site IPR013753 Ras 0.038789
IPR002290 Serine/threonine protein kinase IPR003577 Ras small GTPase, Ras type 0.0138901
IPR011009 Protein kinase-like IPR003577 Ras small GTPase, Ras type 0.00500251

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in NRAS
  • Green Domain is present in both MAPK1 and NRAS

 0.052
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: NRAS

PTMResidueReference
Cysteine methyl ester 186 PubMed, HPRD
Methylation 186 PubMed, HPRD
Prenylation 186 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: NRAS

LocalisationReference
Golgi HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and NRAS that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andNRAS. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and NRAS has 1202 interactors of which there are 923 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for NRAS-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.035
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.025
DIAPH1 Diaphanous 1 20.60 0.046
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.032
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.032
CDK2 CDK2: Cell division protein kinase 2 6.80 0.118
HSPD1 6.11 0.046
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.032
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.046
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.078
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.188
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.063
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 1.42 0.044
PLEK PLEK, P47: Pleckstrin 0.515 0.340
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.038
CRKL CRKL: Crk-like protein 0.461 0.118
JAK1 0.461 0.038
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.225
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.275
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.275
MSN MSN: Moesin 0.461 0.372
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.078
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.275
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.027
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.251
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.036
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.036
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.118
STK10 STK10: Uncharacterized protein STK10 0.385 0.087
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.372
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.063
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.275
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.032
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.225
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.046
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.063
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.063
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.063
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.046
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.078
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 132.00
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.029
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.038
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.171
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.425
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.251
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.416
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.026
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.191
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.036
DOK1 DOK1: Docking protein 1 0.275 0.225
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.372
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.225
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.275
HCK N/A 0.275 0.029
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.129
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.063
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 82.20
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.078
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.127
GAB2 N/A 0.251 0.152
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.032
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.0446
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.127
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.152
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.111
WASPIP N/A 0.233 0.046
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.461
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.040
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.188
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.129
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.241
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.139
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.146
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.188
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.063
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.304
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.078
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.038
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.225
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.275
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.029
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.171
SOS1 SOS1: Son of sevenless homolog 1 0.225 71.40
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.155
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.132
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.052
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.0971
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.0446
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.0554
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.191
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.070
CXorf9 N/A 0.188 0.087
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.372
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.372
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.040
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.118
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.087
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.032
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.188
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.241
RPS6KB1 N/A 0.188 0.233
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.086
FNBP1 N/A 0.188 0.188
GMIP GMIP: GEM-interacting protein 0.188 0.225
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.063
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.0333
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.136
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.029
PSD TYL: TYL protein 0.171 0.097
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.136
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.171
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.225
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 108.00
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.058
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PSCD2 N/A 0.165 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.052
BID BID: BH3-interacting domain death agonist 0.165 0.049
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.028
MAP2K5 N/A 0.165 0.083
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
ARFGAP1 N/A 0.155 0.091
HD HD, IT15: Huntingtin 0.155 0.155
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.060
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.052
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.080
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.060
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.152
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.123
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.032
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.0425
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.025
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.025
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.148
STAT3 0.148 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
ARHGEF7 N/A 0.148 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.075
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.114
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.063
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.063
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.090
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.188
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.063
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 56.60
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.118
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.054
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.043
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.225
ATM ATM: Serine-protein kinase ATM 0.139 0.086
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.139
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.139
CD2AP CD2AP: CD2-associated protein 0.139 0.078
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 41.80
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.225
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.275
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.030
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.030
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.097
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.088
RDX RDX: Radixin 0.136 0.171
VIL2 N/A 0.136 0.225
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.088
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.099
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.029
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.064
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.070
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.046
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.078
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.051
RB1 RB1: Retinoblastoma-associated protein 0.127 0.027
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.060
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.080
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.210
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.0425
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.0971
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.132
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.070
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.026
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.109
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.052
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.077
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.038
PPP1R8 N/A 0.118 0.032
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.040
PGAM1 PGAM1, PGAMA, CDABP0006: Phosphoglycerate mutase 1 0.114 0.032
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.118
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.086
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.056
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.114 0.032
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.069
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.188
CDK5 CDK5: Cell division protein kinase 5 0.114 0.043
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 3.58
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.054
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.086
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.046
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.038
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.054
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.054
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.114
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.046
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.136
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.111
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.111
PLD2 PLD2: Phospholipase D2 0.111 0.136
BMX N/A 0.110 0.098
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.109
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.109
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.065
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.097
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.123
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.056
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.088
PLD1 PLD1: Phospholipase D1 0.097 0.225
DAB1 DAB1: Disabled homolog 1 0.097 0.088
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.078
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.111
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.097
PTMA N/A 0.0971 0.036
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.036
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.340
SP100 N/A 0.0971 0.036
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.096
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.0425
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.036
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.0971
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.039
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.061
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.210
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.062
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.060
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.081
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.027
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.096
CD44 N/A 0.091 0.027
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.111
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.099
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.052
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.070
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.036
IFI16 N/A 0.087 0.0446
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.040
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.054
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.118
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.035
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.086
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.118
CTPS CTPS: CTP synthase 1 0.086 0.063
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.148
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.054
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.054
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.181
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.032
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.097
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.046
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.032
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.071
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.052
MAPKAPK5 N/A 0.083 0.052
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.052
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.052
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.083
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.052
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.052
MAPK15 N/A 0.083 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.052
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.052
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.083 0.041
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.166
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.099
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.188
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.385
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.040
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.078 0.032
LCP1 LCP1, PLS2: Plastin-2 0.078 0.233
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.063
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.038
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.046
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.063
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.078 0.032
HNRPK N/A 0.078 0.129
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.063
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.063
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 0.188
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.046
UBE4A N/A 0.078 0.063
KLHDC4 N/A 0.078 0.046
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.046
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.078 0.032
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.078
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.040
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.039
PRKAA1 N/A 0.077 0.048
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.096
STK16 N/A 0.077 0.060
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.127
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.026
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.039
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.060
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.077
FADD FADD, MORT1: Protein FADD 0.075 0.027
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.047
GIT2 N/A 0.075 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.036
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.036
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.047
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.047
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.047
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.047
SNX3 N/A 0.075 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.075
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.025
CNN2 CNN2: Calponin-2 0.075 0.083
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.047
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.036
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.047
TSC2 TSC2, TSC4: Tuberin 0.075 0.075
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.047
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.047
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.047
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.047
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.047
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.075
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.098
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.047
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.083
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 71.20
PLCB2 0.074 0.044
RIN3 N/A 0.074 0.036
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.032
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.046
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.078
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.032
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.032
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.070 0.030
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.027
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.036
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.0446
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.0446
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.127
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.027
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.307
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.027
KIAA0853 N/A 0.070 0.036
ABCF1 N/A 0.070 0.070
CASP8 N/A 0.070 0.0425
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.0446
TOP2B N/A 0.070 0.027
IFI35 N/A 0.070 0.070
WDR1 N/A 0.070 0.0446
MARK2 N/A 0.070 0.0425
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.087
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.027
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.070
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.111
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.0308
CDK6 CDK6: Cell division protein kinase 6 0.069 0.043
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.071
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.0308
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.136
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.071
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.056
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.071
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.043
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.054
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.035
CDK4 CDK4: Cell division protein kinase 4 0.069 0.087
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.046
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.275
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.111
BCL2L1 BCL2L1, BCL2L, BCLX: Apoptosis regulator Bcl-X 0.0688 0.049
MCL1 MCL1: Induced myeloid leukemia cell differentiation protein Mcl-1 0.0688 0.049
SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 0.067 0.050
BCL2 BCL2: Apoptosis regulator Bcl-2 0.063 0.057
GSK3B N/A 0.063 0.063
CUL4B N/A 0.063 0.040
COPA COPA: Coatomer subunit alpha 0.063 0.129
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.063 0.040
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.063
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.063
PTPN11 N/A 0.063 0.063
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.063 0.032
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.225
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.118
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.032
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.038
NUP153 N/A 0.063 0.040
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.425
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.032
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.063 0.038
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.114
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.078
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.029
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.063
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.078
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.086
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.063
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.038
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.040
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.063 0.032
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.046
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.040
CUL5 CUL5, VACM1: Cullin-5 0.063 0.032
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 0.040
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.063 0.045
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.040
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.067
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.137
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.078
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.372
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.063
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.139
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.046
EXOC2 N/A 0.063 0.046
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.032
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.040
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.032
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.032
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.040
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.040
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.066
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.172
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.032
PPARBP N/A 0.063 0.063
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.040
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.114
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.040
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.063 0.040
FRG1 FRG1: Protein FRG1 0.063 0.063
TIAL1 TIAL1: Nucleolysin TIAR 0.063 0.040
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.078
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.063 0.032
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.048
SPTAN1 N/A 0.062 0.049
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.037
GRLF1 N/A 0.062 0.109
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.060 0.074
SOS2 SOS2: Son of sevenless homolog 2 0.060 0.035
CERK CERK, KIAA1646: Ceramide kinase 0.060 0.036
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.027
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.056
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.088
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.029
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.029
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.071
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.088
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.043
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.035
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.054
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.069
WEE1 WEE1: Wee1-like protein kinase 0.056 0.071
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.049
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.0782
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.062
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.032
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.044
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.042
RAB4A N/A 0.052 0.028
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.036
DNM2 N/A 0.052 0.052
CHUK N/A 0.052 0.052
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.0425
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.0446
FUBP1 N/A 0.052 0.087
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.032
MVP MVP, LRP: Major vault protein 0.052 0.127
NCOA3 N/A 0.052 0.036
SET SET: Protein SET 0.052 0.0446
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.070
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.027
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.052 0.036
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.052
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.027
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.036
LIMS1 N/A 0.052 0.052
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.070
API5 N/A 0.052 0.087
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.036
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.0971
AHNAK AHNAK: AHNAK protein 0.052 0.0425
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.0446
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.027
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.032
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.260
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.127
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.087
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
GRB10 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.113
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.049
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.028
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.050 0.032
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.050 0.050
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.050 0.041
RANBP3 N/A 0.050 0.041
CDKL5 N/A 0.049 0.035
NFIB N/A 0.049 0.072
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.034
DYRK3 N/A 0.049 0.0308
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.043
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.052
MKI67 MKI67: Antigen KI-67 0.048 0.027
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.026
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.025
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.040
EVL N/A 0.046 0.029
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.146
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.046 0.066
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.063
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.040
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.046 0.041
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.063
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.046
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.032
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.032
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.040
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.063
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.063
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.071
SSB SSB: Lupus La protein 0.046 0.040
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.046 0.040
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.032
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.040
CORO1C CORO1C, CRNN4: Coronin-1C 0.046 0.066
BRPF1 BRPF1, BR140: Peregrin 0.046 0.029
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.046
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.046
DLG1 N/A 0.046 0.038
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.038
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.129
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.046 0.038
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.046
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.046
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.063
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.054
XPO1 XPO1, CRM1: Exportin-1 0.046 0.188
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.139
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.032
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.038
SEC31L1 N/A 0.046 0.040
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.046
LPXN LPXN, LDLP: Leupaxin 0.046 0.078
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.086
COPE COPE: Coatomer subunit epsilon 0.046 0.139
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.032
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.038
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.046
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.032
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.129
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.090
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.063
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.078
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.066
SAPS3 N/A 0.046 0.038
SRF SRF: Serum response factor 0.046 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.188
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.032
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.063
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.038
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.078
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.046 0.032
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
COASY COASY, PSEC0106: Bifunctional coenzyme A synthase 0.046 0.032
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.0453 0.027
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.0446 0.036
PIP3-E N/A 0.044 0.036
ARHGAP26 ARHGAP26, GRAF, KIAA0621, OPHN1L: Rho GTPase-activating protein 26 0.044 0.036
CENTB1 CENTB1, KIAA0050: Centaurin-beta 1 0.044 0.044
MYO3A MYO3A: Myosin IIIA 0.044 0.028
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.044
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.031
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.028
CNN3 CNN3: Calponin-3 0.044 0.055
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.031
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.136
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.031
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.0308
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.044
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.098
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.029
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.046
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.027
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.052
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.0425
DAPP1 N/A 0.0425 0.0425
MPG N/A 0.0425 0.052
GNB2L1 Lung cancer oncogene 7 0.0425 0.036
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.036
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.077
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.027
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.027
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.027
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.096
TCOF1 N/A 0.0425 0.027
SREBF2 N/A 0.0425 0.027
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.0425
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.027
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.026
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.042
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.026
LDLRAP1 LDLRAP1, ARH: Low density lipoprotein receptor adapter protein 1 0.041 0.0308
MYLIP MYLIP, BZF1, BM-023, PP5242: E3 ubiquitin-protein ligase MYLIP 0.041 0.0308
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.032
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.099
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.028
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.040
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.040
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.046
MYH9 MYH9: Myosin-9 0.038 0.181
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.038 0.041
RP2 RP2: Protein XRP2 0.038 0.038
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.038 0.040
COPB2 COPB2: Coatomer subunit beta' 0.038 0.032
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.046
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.063
GMFB GMFB: Glia maturation factor beta 0.038 0.029
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.038 0.032
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.029
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 0.063
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.071
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.032
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.063
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.038
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.063
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.038 0.073
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.063
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.063
DYNC1I2 N/A 0.038 0.029
CFL1 CFL1, CFL: Cofilin-1 0.038 0.038
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.032
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.063
CAT CAT: Catalase 0.038 0.038
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.078
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.040
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.078
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.043
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.046
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.139
CHP CHP: Calcium-binding protein p22 0.038 0.086
NOL1 N/A 0.038 0.032
MDN1 MDN1, KIAA0301: Midasin 0.038 0.038
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.046
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.029
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.063
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.046
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.078
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.038 0.032
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.078
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.029
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.046
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.038 0.032
RASA4 RASA4, CAPRI, GAPL, KIAA0538: Ras GTPase-activating protein 4 0.036 0.036
ARAF ARAF, ARAF1, PKS, PKS2: A-Raf proto-oncogene serine/threonine-protein kinase 0.036 0.028
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.036 0.044
PTPN9 0.036 0.036
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.027
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.036
CRLF3 N/A 0.036 0.027
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.036
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.027
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.027
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.027
GLG1 GLG1: Golgi apparatus protein 1 0.036 0.052
TXNDC TXNDC1, TMX, PSEC0085, TXNDC, UNQ235/PRO268: Thioredoxin domain-containing prote 0.035 0.066
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.029
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.026
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.026
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.026
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.033
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.073
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.029
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.096
ZYX ZYX: Zyxin 0.032 0.026
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.027
UBAP2 N/A 0.032 0.0425
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.127
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.036
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.027
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.052
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.032 0.052
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.096
TPR TPR: Nucleoprotein TPR 0.032 0.063
MAN2A1 MAN2A1, MANA2: Alpha-mannosidase 2 0.032 0.078
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.032 0.233
AP2M1 AP2M1, CLAPM1, KIAA0109: AP-2 complex subunit mu-1 0.032 0.046
RYR2 RYR2: Ryanodine receptor 2 0.031 0.032
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.026
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.029
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.032
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.032
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.046
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.086
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.029 0.046
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.056
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.139
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.049
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.032
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.049
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.032
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.032
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.139
THOP1 THOP1: Thimet oligopeptidase 0.029 0.046
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.029 0.038
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 0.032
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.038
SYMPK SYMPK, SPK: Symplekin 0.029 0.038
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.188
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.063
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.029 0.046
IMPAD1 N/A 0.029 0.038
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.086
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.067
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.038
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.063
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.063
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.086
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 0.029 0.038
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.029 0.037
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.046
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.086
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.041
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.046
KIAA0690 N/A 0.029 0.029
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.083
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.04
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.083
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.109
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.049
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.083
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.083
AXIN1 0.028 0.028
MATK 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.152
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PPEF1 N/A 0.028 0.083
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.083
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.052
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.083
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.028 0.036
VAV3 VAV3: Protein vav-3 0.028 0.028
RANBP1 RANBP1: Ran-specific GTPase-activating protein 0.028 0.044
APBB1IP APBB1IP, PREL1, RARP1, RIAM: Amyloid beta A4 precursor protein-binding family B 0.028 0.028
GLRX GLRX, GRX: Glutaredoxin-1 0.027 0.046
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
FAM43A N/A 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
OSBPL9 N/A 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
PSD3 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
LILRB1 N/A 0.027 0.027
ITGAE ITGAE: Integrin alpha-E precursor 0.027 0.036
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.029
PDIA3 PDIA3, ERP57, ERP60, GRP58: Protein disulfide-isomerase A3 precursor 0.026 0.032
TRRAP N/A 0.026 0.0425
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.052
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.026
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.074
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.070
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.052
DBN1 DBN1, D0S117E: Drebrin 0.026 0.032
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.049
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.077
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.0425
ESPL1 N/A 0.026 0.052
PLA2G4A PLA2G4A, CPLA2, PLA2G4: Cytosolic phospholipase A2 0.0253 0.0782
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.075
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.044
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.047
MYO18A 0.025 0.075
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.025
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.075
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.044
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.075
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.075
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.075
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.075
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.036
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.075
RAC1 N/A 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.025
NIPBL N/A 0.025 0.075
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.025
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.044
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
0.299
Total Score 14.00