PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between MAPK1 and TP53

The interaction score between MAPK1 and TP53 is 10.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between MAPK1 and TP53 = 0.28

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

2.88E-3

Orthology

Organism	MAPK1 Orthologue		TP53 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
fly	P40417	1	Q8IH92	0.16

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in MAPK1 and TP53:

Domains in MAPK1

Domains in TP53

IPR000719	Protein kinase
IPR002290	Serine/threonine protein kinase
IPR011009	Protein kinase-like
IPR008271	Serine/threonine protein kinase, active site
IPR003527	MAP kinase
IPR008349	ERK1/2 MAP kinase

IPR008967	p53-like transcription factor, DNA-binding
IPR002117	p53 tumor antigen
IPR010991	p53, tetramerisation
IPR011615	P53_DNA_bd.
IPR012346	P53_RUNT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and TP53 are listed below.

Domain 1		Domain 2		Chi Square
IPR003527	MAP kinase	IPR008967	p53-like transcription factor, DNA-binding	13.3166
IPR008271	Serine/threonine protein kinase, active site	IPR002117	p53 tumor antigen	4.60701
IPR008271	Serine/threonine protein kinase, active site	IPR010991	p53, tetramerisation	4.60701
IPR008271	Serine/threonine protein kinase, active site	IPR011615	P53_DNA_bd.	4.60701
IPR008271	Serine/threonine protein kinase, active site	IPR012346	P53_RUNT_DNA_bd.	4.60701
IPR003527	MAP kinase	IPR012346	P53_RUNT_DNA_bd.	4.12115
IPR003527	MAP kinase	IPR011615	P53_DNA_bd.	4.12115
IPR003527	MAP kinase	IPR010991	p53, tetramerisation	4.12115
IPR003527	MAP kinase	IPR002117	p53 tumor antigen	4.12115
IPR002290	Serine/threonine protein kinase	IPR012346	P53_RUNT_DNA_bd.	3.23646
IPR002290	Serine/threonine protein kinase	IPR011615	P53_DNA_bd.	3.23646
IPR002290	Serine/threonine protein kinase	IPR010991	p53, tetramerisation	3.23646
IPR002290	Serine/threonine protein kinase	IPR002117	p53 tumor antigen	3.23646
IPR008349	ERK1/2 MAP kinase	IPR008967	p53-like transcription factor, DNA-binding	2.09064
IPR002290	Serine/threonine protein kinase	IPR008967	p53-like transcription factor, DNA-binding	1.43889
IPR008271	Serine/threonine protein kinase, active site	IPR008967	p53-like transcription factor, DNA-binding	0.974716
IPR000719	Protein kinase	IPR008967	p53-like transcription factor, DNA-binding	0.163761
IPR011009	Protein kinase-like	IPR012346	P53_RUNT_DNA_bd.	0.00633063
IPR011009	Protein kinase-like	IPR011615	P53_DNA_bd.	0.00633063
IPR011009	Protein kinase-like	IPR002117	p53 tumor antigen	0.00633063
IPR011009	Protein kinase-like	IPR010991	p53, tetramerisation	0.00633063
IPR011009	Protein kinase-like	IPR008967	p53-like transcription factor, DNA-binding	0.00476462
IPR000719	Protein kinase	IPR011615	P53_DNA_bd.	0.000322699
IPR000719	Protein kinase	IPR010991	p53, tetramerisation	0.000322699
IPR000719	Protein kinase	IPR002117	p53 tumor antigen	0.000322699
IPR000719	Protein kinase	IPR012346	P53_RUNT_DNA_bd.	0.000322699

The background colour of the table refers to:

Blue Domain is only present in MAPK1
Yellow Domain is only present in TP53
Green Domain is present in both MAPK1 and TP53

0.083

Post-translational Modifications

Protein: MAPK1

PTM	Residue	Reference
Acetylation	2	PubMed, HPRD
Dephosphorylation	187	PubMed, HPRD
N-acetylalanine	1	HPRD
Phosphorylation	29	PubMed, HPRD
Phosphorylation	41	PubMed, HPRD
Phosphorylation	181	PubMed, HPRD
Phosphorylation	185	PubMed, HPRD
Phosphorylation	187	PubMed, HPRD
Phosphorylation	202	PubMed, HPRD
Phosphothreonine	184	PubMed, HPRD
Phosphotyrosine	186	HPRD

Protein: TP53

PTM	Residue	Reference
Acetylation	305	PubMed, HPRD
Acetylation	320	PubMed, HPRD
Acetylation	370	PubMed, HPRD
Acetylation	372	PubMed, HPRD
Acetylation	373	PubMed, HPRD
Acetylation	381	PubMed, HPRD
Acetylation	382	PubMed, HPRD
Deacylation	382	PubMed, HPRD
Dephosphorylation	315	PubMed, HPRD
N6-acetyllysine	305	HPRD
N6-acetyllysine	373	HPRD
N6-acetyllysine	382	HPRD
Phosphorylation	6	PubMed, HPRD
Phosphorylation	9	PubMed, HPRD
Phosphorylation	15	PubMed, HPRD
Phosphorylation	18	PubMed, HPRD
Phosphorylation	20	PubMed, HPRD
Phosphorylation	33	PubMed, HPRD
Phosphorylation	37	PubMed, HPRD
Phosphorylation	46	PubMed, HPRD
Phosphorylation	55	PubMed, HPRD
Phosphorylation	81	PubMed, HPRD
Phosphorylation	155	PubMed, HPRD
Phosphorylation	315	PubMed, HPRD
Phosphorylation	366	PubMed, HPRD
Phosphorylation	371	PubMed, HPRD
Phosphorylation	378	PubMed, HPRD
Phosphorylation	392	PubMed, HPRD
Phosphoserine	15	PubMed, HPRD
Phosphoserine	46	PubMed, HPRD
Phosphoserine	315	PubMed, HPRD
Phosphothreonine	18	PubMed, HPRD
Phosphothreonine	55	PubMed, HPRD
Proteolytic Cleavage	18	PubMed, HPRD
Proteolytic Cleavage	20	PubMed, HPRD
Proteolytic Cleavage	23	PubMed, HPRD
Sumoylation	386	PubMed, HPRD
Ubiquitination	351	PubMed, HPRD
Ubiquitination	357	PubMed, HPRD
Ubiquitination	370	PubMed, HPRD
Ubiquitination	372	PubMed, HPRD
Ubiquitination	373	PubMed, HPRD
Ubiquitination	381	PubMed, HPRD
Ubiquitination	382	PubMed, HPRD
Ubiquitination	386	PubMed, HPRD

Localisation

Protein: MAPK1

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Protein: TP53

Localisation	Reference
ER	HPRD
Nucleus	HPRD
Mitochondrion	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between MAPK1 and TP53 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andTP53. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and TP53 has 1099 interactors of which there are 919 common interactors.

Common Interactor	Name of Common Interactor	Score for MAPK1-Interactor (?)	Score for TP53-Interactor (?)
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	153.00	0.049
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	115.00	0.069
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	94.70	0.114
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	62.30	0.075
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	62.30	0.075
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	62.30	0.075
DIAPH1	Diaphanous 1	20.60	0.046
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	11.60	0.078
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	7.38	0.078
CDK2	CDK2: Cell division protein kinase 2	6.80	0.078
HSPD1		6.11	0.066
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	4.15	0.078
HSP90AA1	Hsp89-alpha-delta-N	3.95	0.111
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	3.35	0.503
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	2.17	0.233
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	2.02	0.040
DUSP3	DUSP3, VHR: Dual specificity protein phosphatase 3	0.975	0.044
PLEK	PLEK, P47: Pleckstrin	0.515	0.070
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.461	0.069
CRKL	CRKL: Crk-like protein	0.461	0.032
JAK1		0.461	0.051
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.461	0.114
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.461	0.111
ID2	ID2: DNA-binding protein inhibitor ID-2	0.430	0.032
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.416	0.087
ELF1	ELF1: ETS-related transcription factor Elf-1	0.416	0.210
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.416	0.096
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.385	0.046
STK10	STK10: Uncharacterized protein STK10	0.385	0.038
FAM82B	FAM82B, CGI-90: Protein FAM82B	0.376	0.057
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.372	0.114
STAT6	STAT6: Signal transducer and activator of transcription 6	0.372	0.111
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.372	0.063
LYN	LYN: Tyrosine-protein kinase Lyn	0.372	0.061
CSK	CSK: Tyrosine-protein kinase CSK	0.372	0.112
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.372	0.032
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.372	0.051
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.372	0.040
JUND	JUND: Transcription factor jun-D	0.372	0.029
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.372	0.114
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.372	0.032
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.372	0.033
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.372	0.041
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.344	0.704
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.307	0.0425
ROCK1	ROCK1: Rho-associated protein kinase 1	0.307	0.052
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.307	0.087
DOK1	DOK1: Docking protein 1	0.275	0.046
JUNB	JUNB: Transcription factor jun-B	0.275	0.029
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.275	0.112
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.275	0.114
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.275	0.046
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.275	0.046
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.275	0.027
HCK	N/A	0.275	0.033
MAFG	MAFG: Transcription factor MafG	0.275	0.038
ETS1	ETS1, EWSR2: Protein C-ets-1	0.275	0.114
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.275	0.069
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.275	0.141
SYK	SYK: Tyrosine-protein kinase SYK	0.275	0.067
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.275	0.141
LASP1	LASP1, MLN50: LIM and SH3 domain protein 1	0.260	0.027
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.251	0.061
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.251	0.144
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.251	0.036
BACH1	BACH1: Transcription regulator protein BACH1	0.251	0.032
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.233	0.038
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.233	0.032
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.233	0.063
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.233	0.114
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.233	0.066
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.233	0.129
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.233	0.038
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.233	0.046
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.233	0.046
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.233	0.032
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.233	0.146
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.225	0.066
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.225	0.067
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.225	0.029
STAT4	STAT4: Signal transducer and activator of transcription 4	0.225	0.055
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.225	0.063
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.225	0.029
SOS1	SOS1: Son of sevenless homolog 1	0.225	0.054
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.225	0.139
CCNH	CCNH: Cyclin-H	0.225	0.114
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.210	0.155
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.210	0.070
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.210	0.0425
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.210	0.651
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.208	0.964
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.191	0.032
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.191	0.0446
STAT2	STAT2: Signal transducer and activator of transcription 2	0.191	0.096
CXorf9	N/A	0.188	0.188
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.188	0.032
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.188	0.118
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.188
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.188	0.063
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.188	0.038
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.188	0.063
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.188	0.046
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.188	0.129
RPS6KB1	N/A	0.188	0.063
FNBP1	N/A	0.188	0.078
DDX18	DDX18: ATP-dependent RNA helicase DDX18	0.179	0.038
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.174	0.152
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.171	0.318
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.171	0.051
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.165	0.049
NSBP1	NSBP1: Nucleosome-binding protein 1	0.165	0.028
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.165	0.04
BID	BID: BH3-interacting domain death agonist	0.165	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.165	0.083
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.165	0.04
NF2	NF2, SCH: Merlin	0.165	0.028
ARFGAP1	N/A	0.155	0.052
HD	HD, IT15: Huntingtin	0.155	0.036
H1FX	H1FX: Histone H1x	0.155	0.080
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.155	0.026
TRADD	TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein	0.155	0.027
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.155	0.032
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.155	0.0425
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.153	0.031
ERF	ERF: ETS domain-containing transcription factor ERF	0.152	0.155
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.152	0.061
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.152	0.074
ETS2	ETS2: Protein C-ets-2	0.152	0.077
CREB1	CREB1: cAMP response element-binding protein	0.148	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.148	0.137
CCNT2	CCNT2: Cyclin-T2	0.148	0.075
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.148	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.148	0.025
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.148	0.044
EEF2K	EEF2K: Elongation factor 2 kinase	0.148	0.083
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.148	0.075
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.148	0.036
STAT3		0.148	0.049
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.148	0.025
ELMO1	N/A	0.148	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.148	0.075
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.148	0.187
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.148	0.036
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.146	0.0554
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.139	0.078
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.139	0.290
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.139	0.046
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.139	0.227
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.139	0.078
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.139	0.086
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.139	0.078
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.139	0.029
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.139	0.029
ATM	ATM: Serine-protein kinase ATM	0.139	0.086
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.139	0.188
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.139	0.046
CD2AP	CD2AP: CD2-associated protein	0.139	0.040
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.139	0.032
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.139	2.08
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.139	0.086
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.139	0.038
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.137
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.137
CCNB1	Cyclin B1	0.136	0.385
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.136	0.056
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.136	0.284
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.132	0.036
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.129	0.114
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.129	0.038
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.129	0.040
RB1	RB1: Retinoblastoma-associated protein	0.127	0.210
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.127	0.032
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.127	0.032
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.127	0.144
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.127	0.0425
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.127	0.032
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.127	0.087
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.127	0.048
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.127	0.253
ERG	ERG: Transcriptional regulator ERG	0.123	0.077
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	0.123	0.031
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.123	0.132
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.118	0.087
PPP1R8	N/A	0.118	0.063
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.118	0.146
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.118	0.032
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.114	0.063
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.114	0.118
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.114	0.208
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.114	0.029
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.114	0.032
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.114	0.071
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.114	0.056
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.114	0.038
RPS10	RPS10: 40S ribosomal protein S10	0.114	0.032
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.114	0.029
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.114	0.172
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.114	0.029
MYCBP2	MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2	0.111	0.056
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.111	0.037
ELK1	ELK1: ETS domain-containing protein Elk-1	0.111	0.049
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.111	0.049
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.111	0.172
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.111	0.027
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.110	0.032
BMX	N/A	0.110	0.0263
PTPRR	PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor	0.109	0.034
PTPRS	PTPRS: Receptor-type tyrosine-protein phosphatase S precursor	0.109	0.034
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.109	0.055
ETV1	ETV1, ER81: ETS translocation variant 1	0.098	0.056
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.098	0.037
PTPN2	PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2	0.098	0.062
PTPRC	PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ	0.098	0.034
PTPRE	PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor	0.098	0.034
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.098	0.030
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.097	0.033
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.097	0.056
PLD1	PLD1: Phospholipase D1	0.097	0.032
PTMA	N/A	0.0971	0.144
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.0971	0.260
NBN	NBN, NBS, NBS1, P95: Nibrin	0.0971	0.430
SP100	N/A	0.0971	0.525
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.096	0.0425
NFATC1	N/A	0.096	0.096
TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2	0.096	0.162
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.096	0.087
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.096	0.027
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.096	0.0425
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.096	0.430
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.096	0.077
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.096	0.032
SMAD7	SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7	0.096	0.034
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.096	0.430
CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1	0.088	0.086
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.088	0.027
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.087	0.077
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.087	0.070
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.210
IFI16	N/A	0.087	0.087
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.087	0.822
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.087	0.425
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.086	0.038
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.086	0.078
CDK7	CDK7, MO15: Cell division protein kinase 7	0.086	0.078
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.086	0.029
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.086	0.129
CTPS	CTPS: CTP synthase 1	0.086	0.066
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.086	0.087
RELA	RELA, NFKB3: Transcription factor p65	0.086	0.139
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.086	0.067
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.086	0.057
MTA1	MTA1: Metastasis-associated protein MTA1	0.086	0.063
SMAD4	SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4	0.086	1.58
NPM1	NPM1, NPM: Nucleophosmin	0.086	0.129
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.086	0.066
AHR	AHR: Aryl hydrocarbon receptor precursor	0.086	0.032
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.086	0.046
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.083	0.049
MAPKAPK5	N/A	0.083	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.083	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.083
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.083	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.083
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.083	0.152
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.083	0.028
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.083	0.049
MAPK15	N/A	0.083	0.083
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.083
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.083	0.028
HES6	HES6: Transcription cofactor HES-6	0.083	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.083	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.083	0.028
IRF3	IRF3: Interferon regulatory factor 3	0.080	0.132
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.078	0.063
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.078	0.066
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.078	0.188
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.078	0.063
LCP1	LCP1, PLS2: Plastin-2	0.078	0.040
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.078	0.054
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.078	0.026
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.078	0.114
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.063
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.078	0.038
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.078	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.078	0.139
HNRPK	N/A	0.078	0.066
KIAA1012	KIAA1012: Protein TRS85 homolog	0.078	0.139
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.078	0.137
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.078	0.046
KLHDC4	N/A	0.078	0.046
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.078	0.114
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.078	0.046
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.078
MYB	MYB: Myb proto-oncogene protein	0.077	0.176
PRKAA1	N/A	0.077	0.026
STK16	N/A	0.077	0.070
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.077	0.036
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.077	0.046
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.077	0.0425
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.075	0.039
MAX	MAX: Protein max	0.075	0.025
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.075	0.137
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.075	0.025
GIT2	N/A	0.075	0.075
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.075	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.075	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.075	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.075	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.075	0.028
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.075	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.075	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.075	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.075	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.075	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.075	0.047
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.075	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.075
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.075	0.036
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.075	0.028
TFAP4	TFAP4: Transcription factor AP-4	0.075	0.028
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.075	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.075	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.075	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.075	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.075	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.075	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.075	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.075	0.047
CDC2	CDC2: Cell division control protein 2 homolog	0.075	0.028
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.075	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.075	0.028
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.075	0.028
PTPN1	PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1	0.073	0.071
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.071	0.276
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.071	0.0425
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.071	0.032
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.071	0.066
MCM3	MCM3: DNA replication licensing factor MCM3	0.071	0.515
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.071	0.046
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.071	0.385
CAPNS1	CAPNS1, CAPN4, CAPNS: Calpain small subunit 1	0.070	0.027
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.052
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.070	0.155
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.070	0.087
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.070	0.260
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.070	0.052
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.052
GTF3C1	N/A	0.070	0.032
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.070	0.0425
KIAA0853	N/A	0.070	0.070
ABCF1	N/A	0.070	0.144
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.070	0.144
TOP2B	N/A	0.070	0.052
IFI35	N/A	0.070	0.036
WDR1	N/A	0.070	0.070
MARK2	N/A	0.070	0.0425
RGS14	N/A	0.070	0.0425
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.052
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.070
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.070	0.052
SEL1L	SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor	0.070	0.030
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.069	1.58
VDR	VDR, NR1I1: Vitamin D3 receptor	0.069	0.043
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.069	0.046
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.069	0.081
NR4A2	NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2	0.069	0.902
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.069	0.056
CDC20	CDC20: Cell division cycle protein 20 homolog	0.069	0.129
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.069	0.069
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.069	0.063
CDK4	CDK4: Cell division protein kinase 4	0.069	0.129
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.069	0.066
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.069	0.046
GSK3B	N/A	0.063	0.046
CUL4B	N/A	0.063	0.046
COPA	COPA: Coatomer subunit alpha	0.063	0.063
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.063	0.078
ACTG1	ACTB: Actin, cytoplasmic 1	0.063	0.032
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.063	0.040
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.063	0.078
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.063	0.046
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.063	0.233
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.188
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.063	0.0818
NUP153	N/A	0.063	0.129
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.063	0.093
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.078
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.063	0.078
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	0.063	0.040
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.063	0.304
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.063	0.032
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.063	0.078
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.046
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.063	0.233
CUL5	CUL5, VACM1: Cullin-5	0.063	0.046
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.063	0.129
KPNB1	KPNB1, NTF97: Importin subunit beta-1	0.063	0.066
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.063	0.078
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.063	2.54
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.063	0.188
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.063	0.040
ARHGDIB	ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2	0.063	0.032
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.063
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.063
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.063	0.067
EXOC2	N/A	0.063	0.041
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.063	0.233
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.063	0.078
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.063	0.078
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.063	0.139
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.063	0.139
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.063	0.188
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.063	0.704
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.063	0.114
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.063
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.063	0.385
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.063	0.276
EP300	N/A	0.063	0.254
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.063	0.233
PPARBP	N/A	0.063	0.032
YY1	YY1: Transcriptional repressor protein YY1	0.063	0.233
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.063	0.078
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.063	0.129
FRG1	FRG1: Protein FRG1	0.063	0.032
TIAL1	TIAL1: Nucleolysin TIAR	0.063	0.078
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.063	0.066
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.063	0.046
MDM4	MDM4, MDMX: Mdm4 protein	0.062	0.077
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.062	0.026
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.062	0.048
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.062	0.156
GRLF1	N/A	0.062	0.026
GTF2F2	N/A	0.060	0.0971
VIM	VIM: Vimentin	0.060	0.032
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.060
IL12RB2	IL12RB2: Interleukin-12 receptor beta-2 chain precursor	0.057	0.025
HSP90B1	HSP90B1, TRA1: Endoplasmin precursor	0.056	0.046
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.056	0.0818
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.056	0.078
TERT	TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase	0.056	0.026
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.056	0.054
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.056	0.051
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.056	0.026
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.056	0.046
NR1D1	NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1	0.056	0.031
WEE1	WEE1: Wee1-like protein kinase	0.056	0.063
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.055	0.0425
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.055	0.062
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.055	0.048
TP73	TP73, P73: Tumor protein p73	0.055	0.156
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.054	0.241
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.054	0.043
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.054	0.078
SUPT5H	SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5	0.054	0.054
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.052
RAB4A	N/A	0.052	0.028
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.052
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.052	0.430
MECP2	MECP2: Methyl-CpG-binding protein 2	0.052	0.026
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.052	0.032
CHUK	N/A	0.052	0.052
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.052	0.0425
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.052	0.430
FUBP1	N/A	0.052	0.0446
NCOA3	N/A	0.052	0.087
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.052
SET	SET: Protein SET	0.052	0.087
YWHAQ	YWHAQ: 14-3-3 protein theta	0.052	0.027
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.052	0.260
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.052	0.070
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.052	0.0425
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.052
RBM14	RBM14, SIP: RNA-binding protein 14	0.052	0.087
LIMS1	N/A	0.052	0.036
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.052	0.144
MEF2A	N/A	0.052	0.026
API5	N/A	0.052	0.070
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.052	0.430
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.052	0.084
DDX21	DDX21: Nucleolar RNA helicase 2	0.052	0.430
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.052	0.062
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.052	0.087
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.052	0.032
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.052	0.541
SRPR	SRPR: Uncharacterized protein SRPR	0.052	0.036
PTP4A3	PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3	0.050	0.075
NR4A1	CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor	0.050	0.028
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.049	0.032
NFIB	N/A	0.049	0.031
PGR	PGR, NR3C3: Progesterone receptor	0.049	1.00
IL4R	IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor	0.049	0.034
IL6ST	IL6ST: Interleukin-6 receptor subunit beta precursor	0.049	0.034
TRPV1	TRPV1: Vanilloid receptor variant TRPV1b	0.049	0.034
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.049	0.034
TRPV4	TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb	0.049	0.034
LEPR	LEPR, DB, OBR: Leptin receptor precursor	0.049	0.034
PPARG	CREB3L2-PPARgamma	0.049	0.039
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.049	0.0308
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.049	0.114
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	0.049	1.26
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.048	0.132
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.048	0.0446
MKI67	MKI67: Antigen KI-67	0.048	0.144
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.048	0.0453
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.047	0.025
SOX8	SOX8: Transcription factor SOX-8	0.047	0.075
LMNA	LMNA, LMN1: Lamin-A/C	0.047	0.137
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.047
HDAC3	HDAC3: Histone deacetylase 3	0.046	0.129
CDC23	CDC23: Cell division cycle protein 23 homolog	0.046	0.137
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.046	0.276
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.046	0.032
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.046	0.276
SP3	SP3: Transcription factor Sp3	0.046	0.347
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.046	0.043
QARS	QARS: Glutaminyl-tRNA synthetase	0.046	0.066
HSPH1	HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa	0.046	0.032
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.046	0.146
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.046	0.129
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.046	0.129
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.046	0.040
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.046	0.503
SSB	SSB: Lupus La protein	0.046	0.129
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.046	0.129
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.046	0.078
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.046	0.385
CORO1C	CORO1C, CRNN4: Coronin-1C	0.046	0.063
BRPF1	BRPF1, BR140: Peregrin	0.046	0.086
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.046	0.245
MTF1	MTF1: Metal regulatory transcription factor 1	0.046	0.114
PPP2CA	PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	0.046	0.145
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.086
HDAC4	HDAC4, KIAA0288: Histone deacetylase 4	0.046	0.102
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.046	0.086
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.046	0.074
NAPG	NAPG, SNAPG: Gamma-soluble NSF attachment protein	0.046	0.0818
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.046	0.216
EIF2S3	EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3	0.046	0.141
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.046	0.063
XPO1	XPO1, CRM1: Exportin-1	0.046	0.040
FLII	FLII, FLIL: Protein flightless-1 homolog	0.046	0.032
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.046
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.046
PCAF	PCAF: Histone acetyltransferase PCAF	0.046	0.056
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.114
SEC31L1	N/A	0.046	0.063
PREP	PREP, PEP: Prolyl endopeptidase	0.046	0.032
LPXN	LPXN, LDLP: Leupaxin	0.046	0.040
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.046	0.216
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.046	0.210
COPE	COPE: Coatomer subunit epsilon	0.046	0.139
CBX3	CBX3: Chromobox protein homolog 3	0.046	0.129
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.046	0.038
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.046	0.139
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.046	0.066
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.046	0.078
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.046	0.304
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.046	0.038
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.046	0.066
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.046	0.241
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.046	0.086
SAPS3	N/A	0.046	0.046
SRF	SRF: Serum response factor	0.046	0.344
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.046	0.114
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.046	0.188
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.046	0.040
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.046	0.029
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.046	0.040
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.046
WDR44	WDR44: WD repeat-containing protein 44	0.046	0.029
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.046	0.078
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.046	0.063
TH	TH, TYH: Tyrosine 3-monooxygenase	0.046	0.026
PTP4A1	PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1	0.046	0.069
EPOR	EPOR: Erythropoietin receptor precursor	0.0453	0.031
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.044	0.044
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.044	0.035
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.044	0.031
TRPV6	TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6	0.044	0.030
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.043	0.118
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.043	0.146
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.043	0.139
SOX4	SOX4: Transcription factor SOX-4	0.043	0.086
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.0425	0.052
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.0425	0.027
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.0425	0.140
MPG	N/A	0.0425	0.027
GNB2L1	Lung cancer oncogene 7	0.0425	0.087
SH3BP3		0.0425	0.062
SMARCC2	N/A	0.0425	0.0425
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.0425	0.070
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.0425	0.0453
XRCC1	XRCC1: DNA-repair protein XRCC1	0.0425	0.155
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.155
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.0425	0.127
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.0425	0.052
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.0425	0.036
TCOF1	N/A	0.0425	0.087
NUP214	N/A	0.0425	0.026
SREBF2	N/A	0.0425	0.475
DNMT1	DNMT1, AIM, DNMT: DNA	0.0425	0.087
FLT3	FLT3, STK1: FL cytokine receptor precursor	0.041	0.031
RAB8A	RAB8A: RAB8A protein	0.039	0.063
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.038	0.078
HDAC2	HDAC2: Histone deacetylase 2	0.038	0.063
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.038	0.276
RPL8	RPL8: 60S ribosomal protein L8	0.038	0.040
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.038	0.029
MYH9	MYH9: Myosin-9	0.038	0.063
ZFP36	ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline	0.038	0.026
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.038	0.087
PHF10	N/A	0.038	0.063
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.038	0.129
COPB2	COPB2: Coatomer subunit beta'	0.038	0.063
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.038	0.139
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.038	0.032
LDHB	LDHB: L-lactate dehydrogenase B chain	0.038	0.040
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.038	0.129
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.038	0.114
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.038	0.041
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.038	0.188
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.038	0.066
APEH	APEH, D3F15S2, D3S48E, DNF15S2: Acylamino-acid-releasing enzyme	0.038	0.0446
CREBBP	CREBBP, CBP: CREB-binding protein	0.038	0.086
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.038	0.086
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.038	0.276
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.038	0.032
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.127
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.038	0.038
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.038	0.112
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.038	0.188
RNF11	RNF11, CGI-123: RING finger protein 11	0.038	0.050
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.038	0.129
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.038	0.146
WBSCR20A	N/A	0.038	0.063
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.188
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.038	0.129
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.038	0.040
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.038	0.066
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.038	0.129
CCT8	CCT8: Uncharacterized protein CCT8	0.038	0.066
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.038	0.029
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.038	0.078
STUB1	STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1	0.038	0.041
TCP1	CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha	0.038	0.066
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.038	0.063
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.038	0.063
NOL1	N/A	0.038	0.078
MDN1	MDN1, KIAA0301: Midasin	0.038	0.046
EEF2	EEF2, EF2: Elongation factor 2	0.038	0.075
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.038	0.046
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.038	0.046
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.038
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.038	0.078
LAMR1	RPSA, LAMBR, LAMR1: 40S ribosomal protein SA	0.038	0.040
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.038	0.141
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.038	0.129
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.038	0.066
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.038	0.032
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.038	0.063
GHR	GHR: Growth hormone receptor precursor	0.037	0.085
MPL	MPL, TPOR: Thrombopoietin receptor precursor	0.037	0.031
IFNAR1	IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor	0.037	0.025
CRLF3	N/A	0.036	0.063
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.035	0.060
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.035	0.140
PDK1	PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu	0.035	0.094
IL6R	IL6R: Interleukin-6 receptor alpha chain precursor	0.034	0.034
IL9R	IL9R: Interleukin-9 receptor precursor	0.032	0.025
ITGB4	N/A	0.032	0.025
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.032	0.057
RBM6	RBM6, DEF3: RNA-binding protein 6	0.032	0.0425
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.032	0.0425
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.032	0.070
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.077
UBAP2	N/A	0.032	0.070
AFF1	N/A	0.032	0.052
XRCC4	N/A	0.032	0.0425
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.127
TGIF2	TGIF2: Homeobox protein TGIF2	0.032	0.087
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.032	0.430
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.032	0.210
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.032	0.0446
NAT1	NAT1, AAC1: Arylamine N-acetyltransferase 1	0.032	0.027
COIL	COIL, CLN80: Coilin	0.032	0.0425
HIVEP1	N/A	0.032	0.127
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.032
SORL1	SORL1: Sortilin-related receptor precursor	0.032	0.039
CUL2	CUL2: Cullin-2	0.032	0.032
KRT18	KRT18: Uncharacterized protein KRT18	0.031	0.026
SOX11	SOX11: Transcription factor SOX-11	0.0308	0.049
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.029	0.129
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.029	0.046
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.029	0.241
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.029	0.038
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.029	0.063
RBM7		0.029	0.063
GSTP1	GSTP1, FAEES3, GST3: Glutathione S-transferase P	0.029	0.027
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.029
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.029	0.038
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.029	0.139
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.029	0.430
FKBP8	DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment)	0.029	0.029
SP1	SP1, TSFP1: Transcription factor Sp1	0.029	0.056
MYBL2	MYBL2, BMYB: Myb-related protein B	0.029	0.078
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.029	0.063
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.029	0.086
UNG	N/A	0.029	0.087
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.029	0.129
KPNA2	KPNA2, RCH1, SRP1: Importin subunit alpha-2	0.029	0.111
THOP1	THOP1: Thimet oligopeptidase	0.029	0.040
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
POLA2	POLA2: DNA polymerase subunit alpha B	0.029	0.276
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.029	0.038
PPP2CB	PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	0.029	0.0462
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.029	0.029
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.029	0.038
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.029	0.069
PCNA	PCNA: Proliferating cell nuclear antigen	0.029	0.704
SYMPK	SYMPK, SPK: Symplekin	0.029	0.046
LIG1	LIG1: DNA ligase 1	0.029	0.078
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.029	0.032
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	0.029	0.141
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.029	0.027
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.029	0.069
RUNX1	N/A	0.029	0.029
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.029	0.114
H2AFX	H2AFX, H2AX: Histone H2A.x	0.029	4.27
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.029	0.114
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.029	0.040
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.029	0.040
AIP	AIP, XAP2: AH receptor-interacting protein	0.029	0.114
FZR1	N/A	0.029	0.046
CSE1L	CSE1L, CAS, XPO2: Exportin-2	0.029	0.066
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.029	0.038
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.029	0.046
GPI	GPI: Glucose-6-phosphate isomerase	0.029	0.066
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.029	0.069
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.029	0.129
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.029	0.046
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.029	0.129
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.029	0.038
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.029	1.58
CASP3	CASP3, CPP32: Caspase-3 precursor	0.029	0.032
POLB	POLB: DNA polymerase beta	0.029	0.029
COL1A2	COL1A2: Collagen alpha-2(I) chain precursor	0.029	0.029
COL5A2	COL5A2: Collagen alpha-2(V) chain precursor	0.029	0.029
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
IRF7	N/A	0.028	0.028
C13orf8	N/A	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
WDR54	N/A	0.028	0.028
C20orf18	N/A	0.028	0.083
DSP	DSP: Desmoplakin	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.083
CABLES1	N/A	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
SNRPB	N/A	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
ZNF265	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.083
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
HDAC8	N/A	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
S100A16	S100A16, AAG13: Protein S100-A16	0.028	0.049
DUSP15	N/A	0.028	0.028
AXIN1		0.028	0.0333
UHRF1		0.028	0.083
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.083
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
PHLDB2	N/A	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
YWHAG	YWHAG: 14-3-3 protein gamma	0.028	0.0333
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.152
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.083
PPEF1	N/A	0.028	0.083
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
KIF1B	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
CORO6	N/A	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
NASP	NASP: Nuclear autoantigenic sperm protein	0.028	0.049
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.083
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.083
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.152
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.083
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.083
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.083
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.028	0.049
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
FOXL2	FOXL2: Forkhead box protein L2	0.028	0.034
RFX1	RFX1: MHC class II regulatory factor RFX1	0.028	0.0308
CCNG1	CCNG1, CCNG, CYCG1: Cyclin-G1	0.028	0.038
CCNA2	CCNA2, CCN1, CCNA: Cyclin-A2	0.028	0.038
TRRAP	N/A	0.026	0.052
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.026	4.77
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.026
TCF7L2	N/A	0.026	0.090
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.026	0.032
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.026	0.062
CENPA	CENPA: Histone H3-like centromeric protein A	0.026	0.269
EMD	EMD, EDMD, STA: Emerin	0.026	0.052
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.026	0.074
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.026
PHB2	PHB2, BAP, REA: Prohibitin-2	0.026	0.074
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.026	0.039
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.026	0.0425
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.026	0.070
KIF23	N/A	0.026	0.087
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.026	0.070
ESPL1	N/A	0.026	0.144
IL12B	IL12B, NKSF2: Interleukin-12 subunit beta precursor	0.025	0.031
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.075
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.025	0.044
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.075
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.075
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.075
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
TCEA1	N/A	0.025	0.025
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.075
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
HTATIP	N/A	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.075
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
SEC13L1	N/A	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
C20orf77	N/A	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
BRD4	N/A	0.025	0.075
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.075
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
BCOR	N/A	0.025	0.025
MAP2K3	N/A	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.047
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.025	0.036
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.075
GRK6	N/A	0.025	0.025
NUP98	N/A	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.047
RNF20		0.025	0.075
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.075
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
SON		0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
RAB1B	RAB1B: Ras-related protein Rab-1B	0.025	0.025
PRKCB1	N/A	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.047
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.075
ATXN2L	N/A	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
FLJ23436	N/A	0.025	0.028
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.075
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
NIPBL	N/A	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.075
CAMK2A	N/A	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
NES	N/A	0.025	0.028
KCTD1		0.025	0.025
HDAC7A	N/A	0.025	0.028
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.075
DIDO1	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.028
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025

0.299

Total Score

10.30