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Evidence of Interaction Between MAPK1 and BRAF

The interaction score between MAPK1 and BRAF is 38.10.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and BRAF = 0.42

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 4.62E-3
Orthology
OrganismMAPK1 OrthologueBRAF OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P39745 1 Q07292 1
fly P40417 1 P11346 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and BRAF:
Domains in MAPK1Domains in BRAF
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding
IPR003116 Raf-like Ras-binding

The Chi square scores for co-occurrence of domains that are present in MAPK1 and BRAF are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR011009 Protein kinase-like IPR011009 Protein kinase-like 26.2215
IPR003527 MAP kinase IPR008271 Serine/threonine protein kinase, active site 20.8159
IPR008349 ERK1/2 MAP kinase IPR008271 Serine/threonine protein kinase, active site 17.555
IPR008349 ERK1/2 MAP kinase IPR002290 Serine/threonine protein kinase 13.3941
IPR003527 MAP kinase IPR002290 Serine/threonine protein kinase 10.9612
IPR002290 Serine/threonine protein kinase IPR003116 Raf-like Ras-binding 9.96162
IPR002290 Serine/threonine protein kinase IPR008271 Serine/threonine protein kinase, active site 8.88805
IPR008271 Serine/threonine protein kinase, active site IPR001245 Tyrosine protein kinase 8.08585
IPR000719 Protein kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 7.73524
IPR000719 Protein kinase IPR003116 Raf-like Ras-binding 6.69094
IPR000719 Protein kinase IPR008271 Serine/threonine protein kinase, active site 6.25263
IPR008271 Serine/threonine protein kinase, active site IPR008271 Serine/threonine protein kinase, active site 5.82656
IPR002290 Serine/threonine protein kinase IPR001245 Tyrosine protein kinase 5.09618
IPR008271 Serine/threonine protein kinase, active site IPR003116 Raf-like Ras-binding 4.74867
IPR011009 Protein kinase-like IPR003116 Raf-like Ras-binding 4.3316
IPR008349 ERK1/2 MAP kinase IPR000719 Protein kinase 4.26499
IPR002290 Serine/threonine protein kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 3.92759
IPR003527 MAP kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 3.37462
IPR000719 Protein kinase IPR011009 Protein kinase-like 2.94434
IPR011009 Protein kinase-like IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 2.89989
IPR003527 MAP kinase IPR000719 Protein kinase 2.81413
IPR002290 Serine/threonine protein kinase IPR011009 Protein kinase-like 2.72953
IPR008349 ERK1/2 MAP kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 2.53982
IPR008271 Serine/threonine protein kinase, active site IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 2.42446
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR011009 Protein kinase-like IPR008271 Serine/threonine protein kinase, active site 2.11823
IPR003527 MAP kinase IPR001245 Tyrosine protein kinase 1.50703
IPR000719 Protein kinase IPR002290 Serine/threonine protein kinase 0.986464
IPR002290 Serine/threonine protein kinase IPR002290 Serine/threonine protein kinase 0.532451
IPR011009 Protein kinase-like IPR001245 Tyrosine protein kinase 0.178275
IPR003527 MAP kinase IPR011009 Protein kinase-like 0.150555
IPR008349 ERK1/2 MAP kinase IPR011009 Protein kinase-like 0.0192176
IPR008349 ERK1/2 MAP kinase IPR001245 Tyrosine protein kinase 0.0000302204

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in BRAF
  • Green Domain is present in both MAPK1 and BRAF

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: BRAF

PTMResidueReference
Phosphorylation 365 PubMed, HPRD
Phosphorylation 401 PubMed, HPRD
Phosphorylation 429 PubMed, HPRD
Phosphorylation 430 PubMed, HPRD
Phosphorylation 440 PubMed, HPRD
Phosphorylation 446 PubMed, HPRD
Phosphorylation 599 PubMed, HPRD
Phosphorylation 602 PubMed, HPRD
Phosphorylation 729 PubMed, HPRD
Phosphoserine 729 HPRD
Phosphothreonine 373 PubMed, HPRD
Phosphothreonine 401 HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: BRAF

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and BRAF that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andBRAF. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and BRAF has 1513 interactors of which there are 1131 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for BRAF-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 108.00
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.113
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.113
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.098
DUSP14 DUSP14, MKP6: Dual specificity protein phosphatase 14 46.80 0.035
DIAPH1 Diaphanous 1 20.60 0.038
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 12.60 0.027
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 10.50 0.067
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.067
CDK2 CDK2: Cell division protein kinase 2 6.80 0.171
HSPD1 6.11 0.029
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.090
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.086
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.114
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 2.53 0.033
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.171
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.086
GNAI2 Galphai2 protein 1.71 0.0818
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 1.42 0.086
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 1.03 0.041
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.166
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.683 0.044
PLEK PLEK, P47: Pleckstrin 0.515 0.166
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.509 0.041
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.225
CRKL CRKL: Crk-like protein 0.461 0.225
JAK1 0.461 0.225
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.275
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.171
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.225
MSN MSN: Moesin 0.461 0.225
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.275
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.225
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 0.456 0.041
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 0.449 0.033
DUSP7 DUSP7, PYST2: Dual specificity protein phosphatase 7 0.440 0.044
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.191
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.057
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.075
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.126
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 0.405 0.029
STYXL1 STYXL1, DUSP24, MKSTYX: Serine/threonine/tyrosine-interacting-like protein 1 0.402 0.041
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.275
STK10 STK10: Uncharacterized protein STK10 0.385 0.225
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.225
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.113
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.225
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.171
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.148
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.225
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.225
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.171
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.275
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.225
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.171
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.372
JUND JUND: Transcription factor jun-D 0.372 0.067
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.113
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.225
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.171
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.225
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.225
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.046
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.191
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.152
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.191
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.152
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.152
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.166
DOK1 DOK1: Docking protein 1 0.275 0.275
JUNB JUNB: Transcription factor jun-B 0.275 0.051
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.225
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.113
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.372
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.136
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.136
HCK N/A 0.275 0.171
MAFG MAFG: Transcription factor MafG 0.275 0.054
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.067
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 0.041
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.225
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.225
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.225
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.251
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.103
GAB2 N/A 0.251 0.191
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.152
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.166
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.152
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.0453
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.152
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.113
WASPIP N/A 0.233 0.114
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.225
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.067
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.114
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.139
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.225
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.225
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 50.90
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.275
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.225
JUN JUN: Transcription factor AP-1 0.225 0.051
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.225
SH3BP5 N/A 0.225 0.136
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.171
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.225 0.041
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.073
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.225
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.171
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.111
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.136
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 0.051
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.090
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.051
CCNH CCNH: Cyclin-H 0.225 0.090
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.096
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.191
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.096
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.096
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.045
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.192 0.094
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.191
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.191
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.126
CXorf9 N/A 0.188 0.225
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.461
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.225
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.051
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.225
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.171
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.148
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.171
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.275
RPS6KB1 N/A 0.188 0.171
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.225
FNBP1 N/A 0.188 0.225
GMIP GMIP: GEM-interacting protein 0.188 0.114
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.114
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.109
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.171
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.136
PSD TYL: TYL protein 0.171 0.111
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.033
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.097
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.097
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.136
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.171
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.090
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PSCD2 N/A 0.165 0.165
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.165
BID BID: BH3-interacting domain death agonist 0.165 0.049
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.165
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.049
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.165
MAP2K5 N/A 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
ARFGAP1 N/A 0.155 0.091
HD HD, IT15: Huntingtin 0.155 0.0425
H1FX H1FX: Histone H1x 0.155 0.075
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.191
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.127
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.152
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.191
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.166
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.152
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.057
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.109
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.191
SNCB SNCB: Beta-synuclein 0.152 0.152
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.152
ETS2 ETS2: Protein C-ets-2 0.152 0.057
CREB1 CREB1: cAMP response element-binding protein 0.148 0.098
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.148
CCNT2 CCNT2: Cyclin-T2 0.148 0.098
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.098
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.148
STAT3 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
ARHGEF7 N/A 0.148 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.098
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.148
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.071
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.225
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.225
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.148
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.067
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.171
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.114
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.139
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.139 0.041
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.0818
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.139
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.171
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.171
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.136
ATM ATM: Serine-protein kinase ATM 0.139 0.069
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.086
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.275
CD2AP CD2AP: CD2-associated protein 0.139 0.171
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 370.00
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.051
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.136
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.041
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.136
FYN N/A 0.137 0.041
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.097
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.097
RDX RDX: Radixin 0.136 0.111
VIL2 N/A 0.136 0.171
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.136
CCNB1 Cyclin B1 0.136 0.090
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.171
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.136 0.027
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.136
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.136 0.0818
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.090
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.307
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.114
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.046
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.105
RB1 RB1: Retinoblastoma-associated protein 0.127 0.075
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.077
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.152
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.191
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.096
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.251
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.191
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.127
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.166
ERG ERG: Transcriptional regulator ERG 0.123 0.037
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.123
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.123
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.062
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.251
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.038
PPP1R8 N/A 0.118 0.067
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 82.20
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.116 0.070
PGAM1 PGAM1, PGAMA, CDABP0006: Phosphoglycerate mutase 1 0.114 0.155
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.086
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.171
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.069
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.067
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.111
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.225
CDK5 CDK5: Cell division protein kinase 5 0.114 0.275
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.041
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.051
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.086
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.461
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.136
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.139
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.086
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.114
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.114 0.041
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.372
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.041
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.067
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.097
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.097
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.111
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.033
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.136
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 0.171
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.111 0.097
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.111 0.041
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.097
PLD2 PLD2: Phospholipase D2 0.111 0.111
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.109
BMX N/A 0.110 0.098
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.152
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.098
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.123
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.072
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.109 0.081
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.081
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.111
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.029
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.109
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.123
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.111
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.088
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.064
PLD1 PLD1: Phospholipase D1 0.097 0.111
DAB1 DAB1: Disabled homolog 1 0.097 0.088
TST TST: Thiosulfate sulfurtransferase 0.097 0.136
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.097
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.097
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.097
PTMA N/A 0.0971 0.074
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.061
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.152
NFATC1 N/A 0.096 0.057
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.096
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.075
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.077
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.123
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.037
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.096
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.096
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.077
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.0453
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.152
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.126
CD44 N/A 0.091 0.057
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.090 0.051
PTPRZ1 N/A 0.090 0.073
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.064
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.097
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.275
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.032
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.0425
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.0818
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.086
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.136
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.171
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.171
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.136
CTPS CTPS: CTP synthase 1 0.086 0.086
RELA RELA, NFKB3: Transcription factor p65 0.086 0.067
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.139
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.136
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.086 0.086
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.086 0.033
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.051
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.097
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.086
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.069
XPC XPC, XPCC: DNA-repair protein complementing XP-C cells 0.086 0.033
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.165
MAPKAPK5 N/A 0.083 0.083
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.083
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.083
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.049
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.083
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.165
MAPK15 N/A 0.083 0.165
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.049
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.083
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.083
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.083
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.083 0.0308
HMGN4 HMGN4, HMG17L3, NHC: High mobility group nucleosome-binding domain-containing pr 0.083 0.032
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.083 0.041
CTRL PSMB10, MECL1: Proteasome subunit beta type-10 precursor 0.083 0.050
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.0818 0.041
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.088
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.029
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.046
LCP1 LCP1, PLS2: Plastin-2 0.078 0.114
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.046
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.038
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.038
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.038
HNRPK N/A 0.078 0.046
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.114
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.038
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 0.139
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.063
UBE4A N/A 0.078 0.038
KLHDC4 N/A 0.078 0.046
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.275
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.078 0.032
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.225
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.109
MYB MYB: Myb proto-oncogene protein 0.077 0.0453
PRKAA1 N/A 0.077 0.109
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.077
STK16 N/A 0.077 0.251
TSPYL2 TSPYL2, CDA1, HRIHFB2216, DENTT, TSPX: Testis-specific Y-encoded-like protein 2 0.077 0.037
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.152
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.155
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.152
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.109
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.109
ATP2B1 N/A 0.075 0.0453
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.100
FADD FADD, MORT1: Protein FADD 0.075 0.091
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.075
GIT2 N/A 0.075 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
SNX3 N/A 0.075 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.075
CNN2 CNN2: Calponin-2 0.075 0.165
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.098
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.044
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
TSC2 TSC2, TSC4: Tuberin 0.075 0.075
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.044
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.075
PLCB2 0.074 0.036
RIN3 N/A 0.074 0.044
CCND3 CCND3: G1/S-specific cyclin-D3 0.074 0.035
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.073
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.073 0.058
GABRR1 N/A 0.0727 0.0727
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.103
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.065
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.027
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.051
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.067
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.087
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.225
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.054
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.067
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.070 0.051
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.027
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.155
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.127
GTF3C1 N/A 0.070 0.027
ABCF1 N/A 0.070 0.0425
CASP8 N/A 0.070 0.026
IFI35 N/A 0.070 0.052
WDR1 N/A 0.070 0.027
MARK2 N/A 0.070 0.032
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.032
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.027
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.070
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.070 0.042
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.136
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.171
CDK6 CDK6: Cell division protein kinase 6 0.069 0.171
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.111
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.111
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.111
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.041
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.111
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.086
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.111
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.088
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.171
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.225
CDK4 CDK4: Cell division protein kinase 4 0.069 0.225
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.114
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.111
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.136
BCL2L1 BCL2L1, BCL2L, BCLX: Apoptosis regulator Bcl-X 0.0688 0.034
MCL1 MCL1: Induced myeloid leukemia cell differentiation protein Mcl-1 0.0688 0.034
PSMA1 PSMA1, PROS30, PSC2: Proteasome subunit alpha type-1 0.067 0.050
SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 0.067 0.041
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 24.40
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.073
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.063 0.063
BCL2 BCL2: Apoptosis regulator Bcl-2 0.063 0.031
GSK3B N/A 0.063 0.038
COPA COPA: Coatomer subunit alpha 0.063 0.038
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.046
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.046
PTPN11 N/A 0.063 0.046
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.067
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.139
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.046
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.046
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.032
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.063 0.038
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.114
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.046
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.078
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.038
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.038
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.038
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.029
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.171
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.086
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.046
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.038
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.046
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.114
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.032
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.029
EXOC2 N/A 0.063 0.029
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.114
PPARBP N/A 0.063 0.038
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.086
FRG1 FRG1: Protein FRG1 0.063 0.038
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.038
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.096
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.032
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.109
COBL N/A 0.062 0.077
SPTAN1 N/A 0.062 0.152
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.100
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.0453
GRLF1 N/A 0.062 0.152
CHAT CHAT: Choline O-acetyltransferase 0.062 0.062
EIF5 EIF5: Eukaryotic translation initiation factor 5 0.061 0.030
VIM VIM: Vimentin 0.060 0.0453
PSMB1 PSMB1, PSC5: Proteasome subunit beta type-1 precursor 0.060 0.044
PSMA6 PSMA6, PROS27: Proteasome subunit alpha type-6 0.060 0.044
MTMR6 MTMR6: Myotubularin-related protein 6 0.060 0.028
USP8 USP8, KIAA0055, UBPY: Ubiquitin carboxyl-terminal hydrolase 8 0.060 0.028
CCNI CCNI: Cyclin-I 0.060 0.035
PSMA7 PSMA7: Proteasome subunit alpha type-7 0.060 0.060
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.060 0.028
CERK CERK, KIAA1646: Ceramide kinase 0.060 0.036
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.058
GLRA1 N/A 0.058 0.065
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.090
PFKFB2 PFKFB2: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.057 0.057
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.057 0.166
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.057 0.057
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.100
HADHB HADHB, MSTP029: Trifunctional enzyme subunit beta, mitochondrial precursor 0.056 0.076
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.056 0.035
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.057
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.097
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.056
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.114
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.111
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.056 0.032
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 0.056
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.111
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.111
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.275
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.069
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.097
WEE1 WEE1: Wee1-like protein kinase 0.056 0.056
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.056 0.029
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.044
ADD1 ADD1, ADDA: Alpha-adducin 0.055 0.0407
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.059
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.055 0.0453
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.152
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.037
TP73 TP73, P73: Tumor protein p73 0.055 0.030
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.041
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.051
EIF4EBP1 EIF4EBP1: Eukaryotic translation initiation factor 4E-binding protein 1 0.053 0.070
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.053
RAB4A N/A 0.052 0.109
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.027
DNM2 N/A 0.052 0.052
CHUK N/A 0.052 0.032
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.0425
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.027
FUBP1 N/A 0.052 0.0425
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.096
MVP MVP, LRP: Major vault protein 0.052 0.0425
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.307
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.032
LIMS1 N/A 0.052 0.096
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.052
API5 N/A 0.052 0.032
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.0425
AHNAK AHNAK: AHNAK protein 0.052 0.0425
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.036
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.070
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.127
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.032
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.0425
CCNK 0.051 0.051
PSMB4 PSMB4: Proteasome subunit beta type-4 precursor 0.051 0.051
PRH1 PRH1, PRH2: Salivary acidic proline-rich phosphoprotein 1/2 precursor 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
GRB10 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PTPRA N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.051 0.063
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.041
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.051 0.041
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.097
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.049
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.050 0.032
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.050 0.041
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.050 0.0308
RANBP3 N/A 0.050 0.067
ASB8 ASB8, PP14212: Ankyrin repeat and SOCS box protein 8 0.050 0.041
CDKL5 N/A 0.049 0.109
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.049 0.049
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.062
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.04
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.109
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.049 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
DYRK3 N/A 0.049 0.088
AQP1 AQP1, CHIP28: Aquaporin-1 0.049 0.069
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.033
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.136
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.049 0.029
AQP2 AQP2: Aquaporin-2 0.049 0.056
GTF2A1 GTF2A1, TF2A1: Transcription initiation factor IIA subunit 1 0.049 0.033
SORBS3 SORBS3, SCAM1: Vinexin 0.049 0.111
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.0453
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.048
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.048 0.077
MKI67 MKI67: Antigen KI-67 0.048 0.037
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.039
BAD BAD, BBC6, BCL2L8: Bcl2 antagonist of cell death 0.047 0.068
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.075
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.044
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.148
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.044
EVL N/A 0.046 0.029
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.086
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.171
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.063
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.029
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.046
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.063
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.046
BRPF1 BRPF1, BR140: Peregrin 0.046 0.029
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.114
DLG1 N/A 0.046 0.029
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.086
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.038
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.046 0.038
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.086
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.029
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.038
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.032
XPO1 XPO1, CRM1: Exportin-1 0.046 0.038
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.046
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.038
LPXN LPXN, LDLP: Leupaxin 0.046 0.114
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.038
COPE COPE: Coatomer subunit epsilon 0.046 0.188
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.114
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.038
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.067
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.038
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.038
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.038
SAPS3 N/A 0.046 0.046
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.056
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.032
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.038
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.038
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.037
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
TH TH, TYH: Tyrosine 3-monooxygenase 0.046 0.046
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.037
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.046 0.037
HMGCR HMGCR: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.046 0.035
COASY COASY, PSEC0106: Bifunctional coenzyme A synthase 0.046 0.076
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.081
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.0453 0.030
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.081
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.045 0.045
CGA CGA: Glycoprotein hormones alpha chain precursor 0.045 0.045
TSHB TSHB: Thyrotropin subunit beta precursor 0.045 0.045
FSHB FSHB: Follitropin subunit beta precursor 0.045 0.051
LHB LHB: Lutropin subunit beta precursor 0.045 0.045
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.045 0.045
PIP3-E N/A 0.044 0.028
AAMP AAMP: Angio-associated migratory cell protein 0.044 0.047
PSMA4 PSMA4, PSC9: Proteasome subunit alpha type-4 0.044 0.036
MTMR1 MTMR1: Myotubularin-related protein 1 0.044 0.028
CENTB1 CENTB1, KIAA0050: Centaurin-beta 1 0.044 0.028
PSMB9 PSMB9, LMP2, RING12: Proteasome subunit beta type-9 precursor 0.044 0.044
PSMB3 PSMB3: Proteasome subunit beta type-3 0.044 0.074
MYO3A MYO3A: Myosin IIIA 0.044 0.097
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.171
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.056
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.114
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.088
CTTN CTTN, EMS1: Src substrate cortactin 0.044 0.152
CNN3 CNN3: Calponin-3 0.044 0.109
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.136
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.097
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.136
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.136
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.033
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.044
AQP4 AQP4: Aquaporin-4 0.044 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.044
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.044 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.044
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.033
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.233
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.054
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.032
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.032
DAPP1 N/A 0.0425 0.026
MPG N/A 0.0425 0.070
GNB2L1 Lung cancer oncogene 7 0.0425 0.027
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.077
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.027
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.0425
PDE4A N/A 0.0425 0.0425
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.0425
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.026
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.053
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.041 0.033
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.041 0.041
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.057
INHA INHA: Inhibin alpha chain precursor 0.041 0.041
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.041 0.041
NDP NDP: Norrin precursor 0.041 0.041
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.041 0.051
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.051
GLRB GLRB: Glycine receptor subunit beta precursor 0.041 0.033
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.041
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.073
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.041 0.0308
CENTA2 CENTA2: Centaurin-alpha 2 0.041 0.0308
MYLIP MYLIP, BZF1, BM-023, PP5242: E3 ubiquitin-protein ligase MYLIP 0.041 0.0308
FGF9 FGF9: Glia-activating factor precursor 0.041 0.046
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.041 0.046
TBXA2R TBXA2R: Thromboxane A2 receptor 0.04 0.04
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.04 0.04
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.067
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.067
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.099
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.035
RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 0.039 0.076
RAB8A RAB8A: RAB8A protein 0.039 0.0735
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.039 0.093
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.039 0.062
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.077
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.046
RP2 RP2: Protein XRP2 0.038 0.029
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.038
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.046
GMFB GMFB: Glia maturation factor beta 0.038 0.054
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.029
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 0.038
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.086
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.029
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.029
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.029
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.029
DYNC1I2 N/A 0.038 0.029
CFL1 CFL1, CFL: Cofilin-1 0.038 0.087
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.038
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.038
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.029
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.385
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.038
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.029
CHP CHP: Calcium-binding protein p22 0.038 0.114
MDN1 MDN1, KIAA0301: Midasin 0.038 0.029
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.275
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.038
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.038
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.038
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.029
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.038
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.046
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.086
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.038
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.037
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.100
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.081
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.037
GHR GHR: Growth hormone receptor precursor 0.037 0.081
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.081
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.032
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.065
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.072
RAP1GA1 N/A 0.037 0.0453
PFKFB1 N/A 0.037 0.037
CSNK2B CSNK2B, CK2N, G5A: Casein kinase II subunit beta 0.036 0.049
KIAA0372 TTC37, KIAA0372: Tetratricopeptide repeat protein 37 0.036 0.028
PSMB2 PSMB2: Proteasome subunit beta type-2 0.036 0.044
PSMB6 PSMB6, LMPY: Proteasome subunit beta type-6 precursor 0.036 0.074
RASA4 RASA4, CAPRI, GAPL, KIAA0538: Ras GTPase-activating protein 4 0.036 0.028
ARAF ARAF, ARAF1, PKS, PKS2: A-Raf proto-oncogene serine/threonine-protein kinase 0.036 0.060
PTPN9 0.036 0.036
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.075
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.057
CRLF3 N/A 0.036 0.100
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.075
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.057
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.057
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.075
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.075
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.091
RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 0.0354 0.103
TXNDC TXNDC1, TMX, PSEC0085, TXNDC, UNQ235/PRO268: Thioredoxin domain-containing prote 0.035 0.026
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.035
PDK1 PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu 0.035 0.028
KRT20 KRT20: Keratin, type I cytoskeletal 20 0.034 0.032
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.034 0.062
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.034
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.0338 0.038
TPH1 N/A 0.0338 0.0338
MAL2 MAL2: Protein MAL2 0.034 0.034
NOS2A NOS2A, NOS2: Nitric oxide synthase, inducible 0.034 0.030
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
XPNPEP1 N/A 0.033 0.033
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.064
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.033 0.033
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.064
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.073
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.058
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.041
RHO RHO, OPN2: Rhodopsin 0.033 0.029
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.029
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.065
PRLR PRLR: Prolactin receptor precursor 0.033 0.058
F3 F3: Tissue factor precursor 0.032 0.081
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.072
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.072
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.081
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.081
ITGB4 N/A 0.032 0.081
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.032
CP110 N/A 0.032 0.026
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.077
ZYX ZYX: Zyxin 0.032 0.077
MAP2K5 N/A 0.032 0.032
UBAP2 N/A 0.032 0.032
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.032
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.152
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.027
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.0425
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.127
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.126
AP2M1 AP2M1, CLAPM1, KIAA0109: AP-2 complex subunit mu-1 0.032 0.032
RYR2 RYR2: Ryanodine receptor 2 0.031 0.039
KRT18 KRT18: Uncharacterized protein KRT18 0.031 0.032
DES DES: Desmin 0.031 0.127
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 132.00
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.152
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.031 0.0273
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.038
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.030 0.047
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.038
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.030 0.053
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.030 0.030
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
ABCB9 ABCB9, KIAA1520: ATP-binding cassette sub-family B member 9 precursor 0.030 0.030
PA2G4 PA2G4, EBP1: Proliferation-associated protein 2G4 0.030 0.030
RGS3 RGS3: Regulator of G-protein signaling 3 0.030 0.030
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.029
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.090
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.064
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.037
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.072
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.029 0.029
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.029
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.033
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.041
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.058
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.063
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.029 0.046
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.038
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.069
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.086
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.069
THOP1 THOP1: Thimet oligopeptidase 0.029 0.029
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.029 0.038
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.029 0.029
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.038
SYMPK SYMPK, SPK: Symplekin 0.029 0.038
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.029
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.029 0.029
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.046
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.029 0.063
IMPAD1 N/A 0.029 0.029
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.139
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.038
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.038
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.139
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.063
AHCYL1 AHCYL1, DCAL, XPVKONA: Putative adenosylhomocysteinase 2 0.029 0.029
PMM1 PMM1, PMMH22: Phosphomannomutase 1 0.029 0.046
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.046
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.038
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.038
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.083
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.083
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.049
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.083
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.083
AXIN1 0.028 0.083
MATK 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.165
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PPEF1 N/A 0.028 0.083
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.083
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.028 0.046
KRAS N/A 0.0278 0.041
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.136
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0277 0.044
VAV3 VAV3: Protein vav-3 0.028 0.028
RANBP1 RANBP1: Ran-specific GTPase-activating protein 0.028 0.028
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.027 0.041
ACP1 ACP1: Protein-tyrosine-phosphatase, isoform 3 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
FAM43A N/A 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
CDC25B CDC25B, CDC25HU2: M-phase inducer phosphatase 2 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
PSMB5 PSMB5, LMPX: Proteasome subunit beta type-5 precursor 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
PSD3 N/A 0.027 0.027
WDR72 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
LILRB1 N/A 0.027 0.075
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.057
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.027 0.046
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.153
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.037
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.033
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.073
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.065
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.058
TRRAP N/A 0.026 0.032
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.0425
EMD EMD, EDMD, STA: Emerin 0.026 0.036
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.070
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.070
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.155
DBN1 DBN1, D0S117E: Drebrin 0.026 0.060
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.030
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.062
RGS4 RGS4: Regulator of G-protein signaling 4 0.026 0.062
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.027
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.210
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.0425
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.032
ESPL1 N/A 0.026 0.026
OSTF1 N/A 0.0255 0.050
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.025 0.051
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.025 0.051
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.051
F5 F5: Coagulation factor V precursor 0.025 0.051
LMO6 LMO6: LIM domain only protein 6 0.025 0.075
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.075
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.148
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
MYO18A 0.025 0.075
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.047
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.075
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.044
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.075
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.044
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.075
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.148
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.040
PRKCB1 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.075
RAC1 N/A 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.025
NIPBL N/A 0.025 0.025
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.047
SVIL SVIL: Supervillin 0.025 0.025
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.148
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
0.347
Total Score 38.10