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Evidence of Interaction Between MAPK1 and HIST1H1B

The interaction score between MAPK1 and HIST1H1B is 5.86.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and HIST1H1B = -0.02

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismMAPK1 OrthologueHIST1H1B OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YBL016W 1 YPL127C 0.145
bakers yeast YGR040W 0.096 YPL127C 0.145
worm P39745 1 P10771 1
worm P39745 1 P15796 0.52
worm P39745 1 Q19743 1
worm P39745 1 O17536 0.354
worm P39745 1 O01833 0.332
worm P39745 1 O16277 0.419
fly P40417 1 P02255 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and HIST1H1B:
Domains in MAPK1Domains in HIST1H1B
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR005818 Histone H1/H5
IPR005819 Histone H5
IPR011991 Wing_hlx_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and HIST1H1B are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR011991 Wing_hlx_DNA_bd. 16.884
IPR011009 Protein kinase-like IPR011991 Wing_hlx_DNA_bd. 10.5668
IPR008271 Serine/threonine protein kinase, active site IPR011991 Wing_hlx_DNA_bd. 2.3775
IPR002290 Serine/threonine protein kinase IPR011991 Wing_hlx_DNA_bd. 0.686914
IPR003527 MAP kinase IPR011991 Wing_hlx_DNA_bd. 0.0620459

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in HIST1H1B
  • Green Domain is present in both MAPK1 and HIST1H1B

 0.083
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: HIST1H1B

PTMResidueReference
Acetylation 2 PubMed, HPRD
Acetylation 26 PubMed, HPRD
Deacetylation 26 PubMed, HPRD
N-acetylserine 1 HPRD
Phosphorylation 138 PubMed, HPRD
Phosphorylation 155 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: HIST1H1B

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Transitive Score

The common interactors between MAPK1 and HIST1H1B that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andHIST1H1B. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and HIST1H1B has 748 interactors of which there are 654 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for HIST1H1B-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.044
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.025
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.126
CDK2 CDK2: Cell division protein kinase 2 6.80 0.069
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.043
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.033
PLEK PLEK, P47: Pleckstrin 0.515 0.026
JAK1 0.461 0.033
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.097
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.041
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.055
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.123
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.096
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.086
STK10 STK10: Uncharacterized protein STK10 0.385 0.056
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.041
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.111
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.033
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.041
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.033
JUND JUND: Transcription factor jun-D 0.372 0.136
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.171
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.033
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.029
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.033
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.096
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.026
JUNB JUNB: Transcription factor jun-B 0.275 0.111
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.051
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.069
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.049
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.069
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.029
HCK N/A 0.275 0.033
MAFG MAFG: Transcription factor MafG 0.275 0.136
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.056
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 0.111
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.041
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.029
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.030
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.026
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.152
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.090
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.069
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.069
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.069
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.049
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.056
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.056
JUN JUN: Transcription factor AP-1 0.225 0.136
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.041
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.225 0.111
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.056
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.056
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 0.111
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.086
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.114
CCNH CCNH: Cyclin-H 0.225 0.097
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.077
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.096
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.077
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.140
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.216
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.077
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.086
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.111
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.069
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.056
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.029
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.136
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.056
RPS6KB1 N/A 0.188 0.086
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.056
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.028
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.172
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.033
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.029
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.028
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.049
BID BID: BH3-interacting domain death agonist 0.165 0.028
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.083
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.04
MAP2K5 N/A 0.165 0.049
NF2 NF2, SCH: Merlin 0.165 0.028
HD HD, IT15: Huntingtin 0.155 0.126
H1FX H1FX: Histone H1x 0.155 0.062
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.077
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.077
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.062
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.062
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.032
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.037
ETS2 ETS2: Protein C-ets-2 0.152 0.077
CREB1 CREB1: cAMP response element-binding protein 0.148 0.148
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.137
CCNT2 CCNT2: Cyclin-T2 0.148 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.075
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.075
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.044
STAT3 0.148 0.044
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.075
ELMO1 N/A 0.148 0.148
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.148
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.187
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.044
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.073
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.086
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.102
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.069
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.069
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.056
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.056
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.049
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.049
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.069
ATM ATM: Serine-protein kinase ATM 0.139 0.056
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.171
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.069
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.033
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.069
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.111
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.086
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.047
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
CCNB1 Cyclin B1 0.136 0.111
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.029
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.136 0.111
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.136 0.123
RB1 RB1: Retinoblastoma-associated protein 0.127 0.123
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.055
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.077
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.077
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.026
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.077
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.062
ERG ERG: Transcriptional regulator ERG 0.123 0.096
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.038
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.077
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.032
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.056
PPP1R8 N/A 0.118 0.069
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.069
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.056
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.069
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.114 1.02
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.056
CDK5 CDK5: Cell division protein kinase 5 0.114 0.049
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.069
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.069
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.049
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.056
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.056
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.056
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.114 0.103
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.049
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.029
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.049
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.111 0.103
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.033
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.037
BMX N/A 0.110 0.037
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.062
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.037
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.041
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.049
PTMA N/A 0.0971 0.032
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.077
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.077
SP100 N/A 0.0971 0.192
NFATC1 N/A 0.096 0.251
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.031
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.055
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.077
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.152
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.123
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.077
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.055
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.026
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.097
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.041
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.026
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.062
IFI16 N/A 0.087 0.026
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.069
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.069
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.054
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.049
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.056
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.029
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.049
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.086
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.069
RELA RELA, NFKB3: Transcription factor p65 0.086 0.056
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.029
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.033
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.086 0.088
MTA1 MTA1: Metastasis-associated protein MTA1 0.086 0.069
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.216
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.056
TP53 TP53, P53: Cellular tumor antigen p53 0.086 1.26
AHR AHR: Aryl hydrocarbon receptor precursor 0.086 0.056
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.069
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.049
MAPKAPK5 N/A 0.083 0.083
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.049
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.083
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.165
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 1.53
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.049
MAPK15 N/A 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.083
HES6 HES6: Transcription cofactor HES-6 0.083 0.052
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.083
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.062
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.029
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.136
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.078 0.029
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.078 0.056
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.096
MYB MYB: Myb proto-oncogene protein 0.077 0.241
PRKAA1 N/A 0.077 0.062
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.037
STK16 N/A 0.077 0.062
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.037
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.055
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.077
MAX MAX: Protein max 0.075 0.047
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 1.37
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.075
GIT2 N/A 0.075 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 3.97
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.075
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.075
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.075
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.075
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.075
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.075
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.044
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.047
TSC2 TSC2, TSC4: Tuberin 0.075 0.098
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.036
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.075
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.075
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.075
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.075
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.075
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.075
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.075
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.075
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.056
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.136
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.069
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.032
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.096
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.026
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.026
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.032
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.032
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.032
KIAA0853 N/A 0.070 0.026
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.032
TOP2B N/A 0.070 0.026
RGS14 N/A 0.070 0.026
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.032
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.026
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.102
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.056
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.049
MYCN MYCN, NMYC: N-myc proto-oncogene protein 0.069 0.086
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.069 0.056
CDK6 CDK6: Cell division protein kinase 6 0.069 0.069
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.069
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.123
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.069 0.126
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.049
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.069
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.069
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.069
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.069
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.056
CDK4 CDK4: Cell division protein kinase 4 0.069 0.069
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.056
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.041
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.035
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.041
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.033
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.086
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.063 0.036
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.029
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.126
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.171
EXOC2 N/A 0.063 0.041
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.086
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.029
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.029
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.063 0.136
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.069
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.126
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 0.086
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.086
EP300 N/A 0.063 0.158
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.029
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.069
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.033
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.048
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.077
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.062
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.130
GTF2F2 N/A 0.060 0.062
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.062
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.044
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.056 0.056
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.056
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.044
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.033
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.044
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.056
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.033
WEE1 WEE1: Wee1-like protein kinase 0.056 0.069
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.055
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.123
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.055 0.026
TP73 TP73, P73: Tumor protein p73 0.055 0.114
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.136
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.049
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.083
RAB4A N/A 0.052 0.028
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.083
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.026
MECP2 MECP2: Methyl-CpG-binding protein 2 0.052 0.026
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.062
CHUK N/A 0.052 0.032
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.026
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.048
NCOA3 N/A 0.052 0.026
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.077
SET SET: Protein SET 0.052 0.026
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.152
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.052 0.026
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.026
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.026
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.026
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.026
MEF2A N/A 0.052 0.062
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.096
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.026
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.055
ATF2 N/A 0.051 0.051
HES1 HES1, HL, HRY: Transcription factor HES-1 0.050 0.049
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.056
CDKL5 N/A 0.049 0.062
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.049 0.062
NFIB N/A 0.049 0.049
PGR PGR, NR3C3: Progesterone receptor 0.049 0.140
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.062
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.034
DYRK3 N/A 0.049 0.056
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.056
MYF5 MYF5: Myogenic factor 5 0.049 0.056
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.069
GTF2A1 GTF2A1, TF2A1: Transcription initiation factor IIA subunit 1 0.049 0.069
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.062
MKI67 MKI67: Antigen KI-67 0.048 0.062
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.025
SOX8 SOX8: Transcription factor SOX-8 0.047 0.075
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.075
SP3 SP3: Transcription factor Sp3 0.046 0.140
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.056
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.043
BRPF1 BRPF1, BR140: Peregrin 0.046 0.136
MTF1 MTF1: Metal regulatory transcription factor 1 0.046 0.069
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.029
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.046 0.102
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.046 0.136
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.126
XPO1 XPO1, CRM1: Exportin-1 0.046 0.090
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.029
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.029
PCAF PCAF: Histone acetyltransferase PCAF 0.046 0.097
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.046 0.216
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.171
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.097
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.035
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.069
SRF SRF: Serum response factor 0.046 0.140
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 0.029
MYO3A MYO3A: Myosin IIIA 0.044 0.056
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.056
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.033
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.044
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.056
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.044
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.056
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.069
HAND1 HAND1, EHAND: Heart- and neural crest derivatives-expressed protein 1 0.044 0.056
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.030
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.043 0.056
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.043 0.069
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.043 0.069
SOX4 SOX4: Transcription factor SOX-4 0.043 0.086
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.026
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.137
GNB2L1 Lung cancer oncogene 7 0.0425 0.026
SH3BP3 0.0425 0.062
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.062
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.062
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.062
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.026
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.100
TCOF1 N/A 0.0425 0.026
SREBF2 N/A 0.0425 0.114
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.035
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.035
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.086
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.069
PHF10 N/A 0.038 0.029
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.038 0.056
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.111
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.069
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.041
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.029
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.056
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.056
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.086
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.111
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.038 0.029
SATB1 SATB1: DNA-binding protein SATB1 0.038 0.069
FOSB FOSB, G0S3: Protein fosB 0.036 0.028
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.069
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.035 0.172
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.032
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.077
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.026
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.032 0.096
XRCC4 N/A 0.032 0.026
ZFX ZFX: Zinc finger X-chromosomal protein 0.032 0.077
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.081
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.127
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.152
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.123
COIL COIL, CLN80: Coilin 0.032 0.032
HIVEP1 N/A 0.032 0.062
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.032
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.032 0.057
KRT18 KRT18: Uncharacterized protein KRT18 0.031 0.034
SOX11 SOX11: Transcription factor SOX-11 0.0308 0.049
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.136
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.029 0.029
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.069
SP1 SP1, TSFP1: Transcription factor Sp1 0.029 0.056
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.056
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.029 0.056
UNG N/A 0.029 0.029
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.073
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.029
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.136
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.029 0.069
PCNA PCNA: Proliferating cell nuclear antigen 0.029 0.102
SYMPK SYMPK, SPK: Symplekin 0.029 0.069
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.064
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.029
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.029 0.056
RUNX1 N/A 0.029 0.038
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.102
CSE1L CSE1L, CAS, XPO2: Exportin-2 0.029 0.030
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.029 0.069
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.029 0.069
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.111
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.158
KIAA0690 N/A 0.029 0.056
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.029 0.029
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
IRF7 N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
WDR54 N/A 0.028 0.028
C20orf18 N/A 0.028 0.052
DSP DSP: Desmoplakin 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.109
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.083
CABLES1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
SNRPB N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
ZNF265 N/A 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.083
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.083
HDAC8 N/A 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.083
DUSP15 N/A 0.028 0.028
AXIN1 0.028 1.53
UHRF1 0.028 0.028
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.083
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
PHLDB2 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.152
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.083
PPEF1 N/A 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
KIF1B N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.109
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CORO6 N/A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.052
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.083
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.152
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.109
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
FOXL2 FOXL2: Forkhead box protein L2 0.028 0.049
RFX1 RFX1: MHC class II regulatory factor RFX1 0.028 0.136
CREM hCREM-1: HCREM 1alpha protein 0.027 0.027
CREM CREM, RP11-324I22.1-005: cAMP responsive element modulator 0.027 0.027
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.062
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.062
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.026
TCF7L2 N/A 0.026 0.100
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.026
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.026 0.077
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.026
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.055
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.077
KIF23 N/A 0.026 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.026
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.075
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.075
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.148
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
TCEA1 N/A 0.025 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.075
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
HTATIP N/A 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.075
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
SEC13L1 N/A 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
C20orf77 N/A 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
BRD4 N/A 0.025 0.148
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.075
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.075
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.148
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.075
GRK6 N/A 0.025 0.025
NUP98 N/A 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.075
RNF20 0.025 0.075
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.075
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
SON 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
ATXN2L N/A 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.075
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
FLJ23436 N/A 0.025 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
NIPBL N/A 0.025 0.148
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
CAMK2A N/A 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
NES N/A 0.025 0.025
KCTD1 0.025 0.025
HDAC7A N/A 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.047
DIDO1 N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
0.299
Total Score 5.86