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Evidence of Interaction Between MAPK1 and CRKL

The interaction score between MAPK1 and CRKL is 64.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and CRKL = 0.61

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology
OrganismMAPK1 OrthologueCRKL OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YBL016W 1 YBL007C 0.053
bakers yeast YGR040W 0.096 YBL007C 0.053
worm P39745 1 Q9NHC3 0.438
fly P40417 1 Q9XYM0 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and CRKL:
Domains in MAPK1Domains in CRKL
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001452 SH3
IPR000980 SH2 motif
IPR011511 SH3_2.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and CRKL are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR008271 Serine/threonine protein kinase, active site IPR000980 SH2 motif 41.4368
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR008271 Serine/threonine protein kinase, active site IPR001452 SH3 27.0049
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR002290 Serine/threonine protein kinase IPR000980 SH2 motif 18.5445
IPR002290 Serine/threonine protein kinase IPR001452 SH3 11.0285
IPR008271 Serine/threonine protein kinase, active site IPR011511 SH3_2. 6.47825
IPR002290 Serine/threonine protein kinase IPR011511 SH3_2. 4.77172
IPR003527 MAP kinase IPR000980 SH2 motif 3.65309
IPR008349 ERK1/2 MAP kinase IPR001452 SH3 1.37932
IPR003527 MAP kinase IPR001452 SH3 0.988997
IPR008349 ERK1/2 MAP kinase IPR000980 SH2 motif 0.969135
IPR000719 Protein kinase IPR011511 SH3_2. 0.0847071
IPR011009 Protein kinase-like IPR011511 SH3_2. 0.00500251

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in CRKL
  • Green Domain is present in both MAPK1 and CRKL

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: CRKL

PTMResidueReference
Phosphorylation 107 PubMed, HPRD
Phosphorylation 207 PubMed, HPRD
Phosphotyrosine 207 HPRD
Phosphotyrosine 251 HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: CRKL

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and CRKL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andCRKL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and CRKL has 1611 interactors of which there are 1104 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for CRKL-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.111
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.090
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.113
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.098
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.148
DUSP2 DUSP2, PAC1: Dual specificity protein phosphatase 2 31.70 0.029
DIAPH1 Diaphanous 1 20.60 0.063
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.040
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 10.50 0.040
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.040
CDK2 CDK2: Cell division protein kinase 2 6.80 0.372
HSPD1 6.11 0.063
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.040
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.063
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.078
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.275
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.461
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 1.42 0.031
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.065
PLEK PLEK, P47: Pleckstrin 0.515 0.202
MSN MSN: Moesin 0.461 0.275
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.275
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 2.94
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 14.60
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.171
JAK1 0.461 1.78
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.225
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.225
DUSP7 DUSP7, PYST2: Dual specificity protein phosphatase 7 0.440 0.028
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.166
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.027
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.191
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.036
STYXL1 STYXL1, DUSP24, MKSTYX: Serine/threonine/tyrosine-interacting-like protein 1 0.402 0.050
STK10 STK10: Uncharacterized protein STK10 0.385 0.275
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.114
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.275
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.078
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 1.78
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.372
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 1.35
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 1.35
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.225
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 132.00
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.181
LYN LYN: Tyrosine-protein kinase Lyn 0.372 1.78
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.225
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.040
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.275
CSK CSK: Tyrosine-protein kinase CSK 0.372 2.94
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.233
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.275
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.583
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.191
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.191
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.251
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.0446
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.191
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.251
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.275
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 1.35
HCK N/A 0.275 1.07
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.225
SYK SYK: Tyrosine-protein kinase SYK 0.275 1.78
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.078
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.078
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.225
DOK1 DOK1: Docking protein 1 0.275 0.225
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 2.94
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.245
DUSP11 DUSP11, PIR1: RNA/RNP complex-1-interacting phosphatase 0.274 0.035
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.251
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.103
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 1.98
GAB2 N/A 0.251 0.191
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.0446
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.251
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.123
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.275
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.233
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.461
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.275
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.275
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.032
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 14.60
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.0818
WASPIP N/A 0.233 14.60
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.225
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.372
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.032
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.372
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.171
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.148
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.171
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.148
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.078
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 430.00
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.275
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.090
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.251
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.036
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.307
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.416
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.052
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.075
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.251
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.126
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.191
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.275
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.461
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.275
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.304
RPS6KB1 N/A 0.188 0.372
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.171
FNBP1 N/A 0.188 10.60
GMIP GMIP: GEM-interacting protein 0.188 0.114
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.118
CXorf9 N/A 0.188 0.275
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.139
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.040
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.372
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.461
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.0333
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.171
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.073
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.136
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.136
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 108.00
PSD TYL: TYL protein 0.171 0.097
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.171
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.171
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.083
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 1.30
MAP2K5 N/A 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 1.30
PSCD2 N/A 0.165 0.165
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.152
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.0425
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.251
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.191
HD HD, IT15: Huntingtin 0.155 0.210
ARFGAP1 N/A 0.155 0.027
H1FX H1FX: Histone H1x 0.155 0.027
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.126
SNCB SNCB: Beta-synuclein 0.152 0.034
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.152
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 1.98
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 1.20
ETS2 ETS2: Protein C-ets-2 0.152 0.100
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.191
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 1.17
STAT3 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
ARHGEF7 N/A 0.148 0.148
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 46.90
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 1.17
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.075
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.047
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.047
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.118
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.188
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.046
ATM ATM: Serine-protein kinase ATM 0.139 0.225
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.046
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.372
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.032
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.275
CD2AP CD2AP: CD2-associated protein 0.139 0.372
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.225
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.275
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.078
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.245
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.032
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.225
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.275
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.275
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.171
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.225
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.372
FYN N/A 0.137 0.402
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.030
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 1.37
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.097
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.029
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.073
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.088
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.097
RDX RDX: Radixin 0.136 0.171
CCNB1 Cyclin B1 0.136 0.032
VIL2 N/A 0.136 0.225
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.088
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.155
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.129 0.032
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.146
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.046
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.063
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.191
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.052
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.191
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.307
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.416
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.087
RB1 RB1: Retinoblastoma-associated protein 0.127 0.027
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.251
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.166
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.152
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.123
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.0425
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.191
PPP1R8 N/A 0.118 0.040
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.032
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.118
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.063
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.275
CDK5 CDK5: Cell division protein kinase 5 0.114 0.136
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.171
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.171
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.171
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.111
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.063
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.171
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.046
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.225
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.372
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.225
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.069
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.032
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.097
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.874
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 65.60
PLD2 PLD2: Phospholipase D2 0.111 0.171
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 5.88
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.136
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 1.07
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.975
BMX N/A 0.110 0.775
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.081
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.081
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.109
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.098
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.031
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.097
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.859
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.098
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.098
TST TST: Thiosulfate sulfurtransferase 0.097 0.035
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.111
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.099
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.111
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 1.07
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.088
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.064
PLD1 PLD1: Phospholipase D1 0.097 0.171
DAB1 DAB1: Disabled homolog 1 0.097 0.136
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.0446
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.036
SP100 N/A 0.0971 0.036
PTMA N/A 0.0971 0.0446
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.027
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.032
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.132
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.191
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.123
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.126
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.152
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.036
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.191
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.191
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.0425
CD44 N/A 0.091 0.061
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.166
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.090 0.051
PTPRZ1 N/A 0.090 0.064
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.088
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 1.07
IFI16 N/A 0.087 0.036
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.070
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.052
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.0446
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.040
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.181
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.225
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.171
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.040
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.097
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.063
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.032
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.275
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.225
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.032
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.111
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.372
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.275
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.097
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.171
CTPS CTPS: CTP synthase 1 0.086 0.063
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.028
MAPK15 N/A 0.083 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.165
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.165
HES6 HES6: Transcription cofactor HES-6 0.083 0.049
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.165
MAPKAPK5 N/A 0.083 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.165
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.083 0.402
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.083 0.041
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.0818 0.181
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.091
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.078
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 0.078
HNRPK N/A 0.078 0.078
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.063
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.063
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.063
UBE4A N/A 0.078 0.063
KLHDC4 N/A 0.078 0.063
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.046
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.063
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.040
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.078
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.032
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.063
LCP1 LCP1, PLS2: Plastin-2 0.078 0.118
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.063
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.046
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.078
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.029
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.191
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.026
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.191
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.152
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.251
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.123
PRKAA1 N/A 0.077 0.152
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.191
STK16 N/A 0.077 0.251
FADD FADD, MORT1: Protein FADD 0.075 0.036
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.075 0.0453
ATP2B1 N/A 0.075 0.037
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.126
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.148
CNN2 CNN2: Calponin-2 0.075 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.148
SNX3 N/A 0.075 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.098
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
TSC2 TSC2, TSC4: Tuberin 0.075 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 1.17
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.098
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.148
GIT2 N/A 0.075 0.025
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.098
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.148
RIN3 N/A 0.074 0.036
PLCB2 0.074 0.036
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.113
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.041
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.072
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.063
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.146
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.040
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.245
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.032
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.181
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.032
KIAA0853 N/A 0.070 0.036
ABCF1 N/A 0.070 0.087
CASP8 N/A 0.070 0.0425
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.074
TOP2B N/A 0.070 0.036
IFI35 N/A 0.070 0.0425
WDR1 N/A 0.070 0.027
MARK2 N/A 0.070 0.0425
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.036
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.0971
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.070
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.036
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.0446
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.127
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.027
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.027
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.052
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.027
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.027
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.111
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.032
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.111
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.275
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.111
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.171
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.111
CDK4 CDK4: Cell division protein kinase 4 0.069 0.372
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.063
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.225
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.171
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.088
CDK6 CDK6: Cell division protein kinase 6 0.069 0.171
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.225
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.097
SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 0.067 0.041
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 388.00
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.064
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.040
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.063 0.032
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.063
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.038
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.245
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.032
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.078
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.275
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.040
CUL5 CUL5, VACM1: Cullin-5 0.063 0.032
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 0.040
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.040
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.063 0.032
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.063
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.146
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.071
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.032
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 1.32
EXOC2 N/A 0.063 0.038
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.040
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.040
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.040
EP300 N/A 0.063 0.032
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.040
PPARBP N/A 0.063 0.063
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.040
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.087
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.040
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.063 0.040
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.040
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.040
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 0.032
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.032
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.040
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.040
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.054
TIAL1 TIAL1: Nucleolysin TIAR 0.063 0.040
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.078
FRG1 FRG1: Protein FRG1 0.063 0.063
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.233
PTPN11 N/A 0.063 0.063
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.063 0.066
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.067
GSK3B N/A 0.063 0.038
CUL4B N/A 0.063 0.032
COPA COPA: Coatomer subunit alpha 0.063 0.063
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.063 0.040
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.118
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.087
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.078
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.032
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.063
NUP153 N/A 0.063 0.040
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.078
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.040
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.063 0.038
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.063
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.233
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.029
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.078
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.029
SPTAN1 N/A 0.062 0.109
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.081
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.100
GRLF1 N/A 0.062 0.062
COBL N/A 0.062 0.098
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.152
GTF2F2 N/A 0.060 0.027
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.060 0.074
SOS2 SOS2: Son of sevenless homolog 2 0.060 0.029
CERK CERK, KIAA1646: Ceramide kinase 0.060 0.044
MTMR6 MTMR6: Myotubularin-related protein 6 0.060 0.036
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.065
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.065
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.081
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.0453
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.114
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.099
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.275
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.111
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.136
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.111
WEE1 WEE1: Wee1-like protein kinase 0.056 0.275
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.029
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.046
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.097
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.275
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 370.00
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.050
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.0782
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.123
TP73 TP73, P73: Tumor protein p73 0.055 0.081
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.245
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.032
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.044
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.034
RAB4A N/A 0.052 0.04
LIMS1 N/A 0.052 0.052
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.052 0.036
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.052
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.036
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.036
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.087
API5 N/A 0.052 0.070
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.027
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.052
AHNAK AHNAK: AHNAK protein 0.052 0.032
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.0446
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.036
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.070
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.032
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.070
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.032
FUBP1 N/A 0.052 0.260
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.026
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.036
DNM2 N/A 0.052 0.052
CHUK N/A 0.052 0.052
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.0425
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.0446
NCOA3 N/A 0.052 0.027
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.036
SET SET: Protein SET 0.052 0.074
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.070
MVP MVP, LRP: Major vault protein 0.052 0.032
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.0446
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
GRB10 N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.090
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.051 0.051
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.088
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.088
HES1 HES1, HL, HRY: Transcription factor HES-1 0.050 0.026
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.050 0.050
RANBP3 N/A 0.050 0.050
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.050 0.0308
ASB8 ASB8, PP14212: Ankyrin repeat and SOCS box protein 8 0.050 0.050
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.050 0.053
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.109
CDKL5 N/A 0.049 0.098
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.109
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.980
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.109
EDA N/A 0.049 0.049
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.049 0.049
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.049 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.109
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.111
SORBS3 SORBS3, SCAM1: Vinexin 0.049 0.111
DYRK3 N/A 0.049 0.097
MKI67 MKI67: Antigen KI-67 0.048 0.027
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.026
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.027
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.081
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.052
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.075
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.098
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.046 0.063
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.063
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.029
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.078
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.0818
XPO1 XPO1, CRM1: Exportin-1 0.046 0.078
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.071
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.038
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.078
SEC31L1 N/A 0.046 0.032
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.038
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.032
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.046
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.032
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.038
COPE COPE: Coatomer subunit epsilon 0.046 0.046
LPXN LPXN, LDLP: Leupaxin 0.046 0.046
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.129
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.040
SAPS3 N/A 0.046 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.040
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.225
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.063
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.090
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.078
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.066
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.078
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.046 0.032
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.046 0.032
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 0.032
SRF SRF: Serum response factor 0.046 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.046
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.032
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.078
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.063
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.063
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.046 0.113
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.063
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.040
EVL N/A 0.046 0.038
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.078
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.046 0.040
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.063
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.040
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.233
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.063
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.063
SSB SSB: Lupus La protein 0.046 0.040
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.046 0.040
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.046
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.040
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.040
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.040
DLG1 N/A 0.046 0.038
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.032
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.032
BRPF1 BRPF1, BR140: Peregrin 0.046 0.038
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.063
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.046
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.100
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.058
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.100
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.0453 0.0453
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.0453 0.075
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.0453 0.081
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.126
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.0446 0.036
MTMR1 MTMR1: Myotubularin-related protein 1 0.044 0.044
ARHGAP26 ARHGAP26, GRAF, KIAA0621, OPHN1L: Rho GTPase-activating protein 26 0.044 0.028
CENTB1 CENTB1, KIAA0050: Centaurin-beta 1 0.044 0.044
PIP3-E N/A 0.044 0.028
CNN3 CNN3: Calponin-3 0.044 0.088
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.097
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.111
CTTN CTTN, EMS1: Src substrate cortactin 0.044 2.77
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.097
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.111
MYO3A MYO3A: Myosin IIIA 0.044 0.088
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.097
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.097
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.099
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.098
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.044
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.029
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.038
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.073
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.043 0.032
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.043 0.032
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.048
SMARCC2 N/A 0.0425 0.027
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.027
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.036
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.027
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.036
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.052
SREBF2 N/A 0.0425 0.027
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.032
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.036
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.048
TCOF1 N/A 0.0425 0.0446
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.027
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.0425
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.026
DAPP1 N/A 0.0425 0.032
MPG N/A 0.0425 0.052
GNB2L1 Lung cancer oncogene 7 0.0425 0.0446
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.053
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.041
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.808
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.058
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 388.00
MYLIP MYLIP, BZF1, BM-023, PP5242: E3 ubiquitin-protein ligase MYLIP 0.041 0.041
LDLRAP1 LDLRAP1, ARH: Low density lipoprotein receptor adapter protein 1 0.041 0.041
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.041 0.041
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.0818
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.113
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.099
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.078
RAB8A RAB8A: RAB8A protein 0.039 0.026
RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 0.039 0.037
DYNC1I2 N/A 0.038 0.029
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.038
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.188
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.063
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.063
WBSCR20A N/A 0.038 0.032
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.063
CAT CAT: Catalase 0.038 0.038
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.078
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.137
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.129
CFL1 CFL1, CFL: Cofilin-1 0.038 0.038
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.032
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.063
CHP CHP: Calcium-binding protein p22 0.038 0.054
NOL1 N/A 0.038 0.040
MDN1 MDN1, KIAA0301: Midasin 0.038 0.063
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.038 0.032
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.029
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.046
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.078
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.063
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.038 0.032
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.038
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.078
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.038 0.040
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.046
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.063
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.038 0.066
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.046
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.063
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.225
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.032
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.040
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.063
MYH9 MYH9: Myosin-9 0.038 0.067
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.063
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.063
GMFB GMFB: Glia maturation factor beta 0.038 0.029
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.038 0.040
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.046
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.038 0.111
PHF10 N/A 0.038 0.032
RP2 RP2: Protein XRP2 0.038 0.029
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.038 0.040
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.038
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.032
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.063
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 0.078
GHR GHR: Growth hormone receptor precursor 0.037 0.100
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.081
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.126
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.100
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.100
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.166
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.126
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.126
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.126
ARAF ARAF, ARAF1, PKS, PKS2: A-Raf proto-oncogene serine/threonine-protein kinase 0.036 0.036
PTPN9 0.036 0.028
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.036 0.036
RASA2 RASA2, GAP1M, RASGAP: Ras GTPase-activating protein 2 0.036 0.028
GABPA GABPA, E4TF1A: GA-binding protein alpha chain 0.036 0.035
RASA4 RASA4, CAPRI, GAPL, KIAA0538: Ras GTPase-activating protein 4 0.036 0.036
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.126
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.202
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.166
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.202
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.202
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.202
CRLF3 N/A 0.036 0.274
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.274
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.274
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.029
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.034
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.0338 0.0338
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
MAL2 MAL2: Protein MAL2 0.034 0.034
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.064
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.033 0.029
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.064
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.058
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.090
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.058
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.032
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.065
PRLR PRLR: Prolactin receptor precursor 0.033 0.0727
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.100
ITGB4 N/A 0.032 0.081
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.065
F3 F3: Tissue factor precursor 0.032 0.072
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.032 0.032
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.100
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.027
UBAP2 N/A 0.032 0.052
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.027
AFF1 N/A 0.032 0.027
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.052
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.036
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.036
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.070
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.032 0.0425
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.127
CP110 N/A 0.032 0.032
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.048
ZYX ZYX: Zyxin 0.032 0.026
MAP2K5 N/A 0.032 0.032
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.032 0.032
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.148
TPR TPR: Nucleoprotein TPR 0.032 0.032
RYR2 RYR2: Ryanodine receptor 2 0.031 0.025
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.044
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.0308
PTPN7 PTPN7: Tyrosine-protein phosphatase non-receptor type 7 0.0308 0.041
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.047
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.0338
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.058
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.065
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 281.00
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.029 0.065
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.072
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.032
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.065
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.058
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.655
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.063
PCNA PCNA: Proliferating cell nuclear antigen 0.029 0.032
SYMPK SYMPK, SPK: Symplekin 0.029 0.029
LIG1 LIG1: DNA ligase 1 0.029 0.090
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.038
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.029 0.046
IMPAD1 N/A 0.029 0.029
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.086
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.046
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.038
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 0.029 0.046
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.038
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.245
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.038
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.063
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.046
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.063
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.029 0.032
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.029 0.032
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.046
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.181
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.046
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.029
RBM7 0.029 0.032
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.029 0.038
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.032
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.032
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.043
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.032
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.038
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.032
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.038
THOP1 THOP1: Thimet oligopeptidase 0.029 0.046
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.029 0.063
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 0.032
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.029
AXIN1 0.028 0.028
MATK 0.028 0.028
PHLDB2 N/A 0.028 0.028
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.052
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.052
PPEF1 N/A 0.028 0.052
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.083
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.083
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.028 0.037
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.0308
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.028 0.028
VAV3 VAV3: Protein vav-3 0.028 0.028
MTM1 MTM1, CG2: Myotubularin 0.028 0.028
RANBP1 RANBP1: Ran-specific GTPase-activating protein 0.028 0.074
APBB1IP APBB1IP, PREL1, RARP1, RIAM: Amyloid beta A4 precursor protein-binding family B 0.028 0.028
SLC2A1 SLC2A1, GLUT1: Solute carrier family 2, facilitated glucose transporter member 1 0.027 0.422
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.265
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
PSD3 N/A 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
FAM43A N/A 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.202
CD69 CD69: Early activation antigen CD69 0.027 0.027
LILRB1 N/A 0.027 0.126
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.126
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.0453
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.073
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.655
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 250.00
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.064
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.210
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.859
DBN1 DBN1, D0S117E: Drebrin 0.026 0.026
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.210
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.031
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.048
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.091
KIF23 N/A 0.026 0.091
IREB2 IREB2: Iron-responsive element-binding protein 2 0.026 0.032
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.0425
MT3 MT3: Metallothionein-3 0.026 0.037
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.070
ESPL1 N/A 0.026 0.052
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
TRRAP N/A 0.026 0.052
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.052
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.274
OSTF1 N/A 0.0255 0.050
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0253 0.047
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.051
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.075
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.098
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.047
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.098
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.025
NIPBL N/A 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.047
RAC1 N/A 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.047
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.025
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.047
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.047
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.366
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.047
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
MYO18A 0.025 0.075
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.025
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.075
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.036
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
0.347
Total Score 64.00