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Evidence of Interaction Between MAPK1 and LIMK1

The interaction score between MAPK1 and LIMK1 is 5.29.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and LIMK1 = -0.19

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.48E-3
Orthology
OrganismMAPK1 OrthologueLIMK1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly P40417 1 Q8IR79 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and LIMK1:
Domains in MAPK1Domains in LIMK1
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008271 Serine/threonine protein kinase, active site
IPR001781 Zn-binding protein, LIM
IPR001478 PDZ/DHR/GLGF domain

The Chi square scores for co-occurrence of domains that are present in MAPK1 and LIMK1 are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR003527 MAP kinase IPR008271 Serine/threonine protein kinase, active site 20.8159
IPR008349 ERK1/2 MAP kinase IPR008271 Serine/threonine protein kinase, active site 17.555
IPR002290 Serine/threonine protein kinase IPR008271 Serine/threonine protein kinase, active site 8.88805
IPR000719 Protein kinase IPR001478 PDZ/DHR/GLGF domain 8.68759
IPR008271 Serine/threonine protein kinase, active site IPR001245 Tyrosine protein kinase 8.08585
IPR011009 Protein kinase-like IPR001478 PDZ/DHR/GLGF domain 6.814
IPR000719 Protein kinase IPR008271 Serine/threonine protein kinase, active site 6.25263
IPR008271 Serine/threonine protein kinase, active site IPR008271 Serine/threonine protein kinase, active site 5.82656
IPR002290 Serine/threonine protein kinase IPR001245 Tyrosine protein kinase 5.09618
IPR008349 ERK1/2 MAP kinase IPR000719 Protein kinase 4.26499
IPR011009 Protein kinase-like IPR000719 Protein kinase 2.94434
IPR003527 MAP kinase IPR000719 Protein kinase 2.81413
IPR008271 Serine/threonine protein kinase, active site IPR001478 PDZ/DHR/GLGF domain 2.78154
IPR002290 Serine/threonine protein kinase IPR001478 PDZ/DHR/GLGF domain 2.76053
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR011009 Protein kinase-like IPR008271 Serine/threonine protein kinase, active site 2.11823
IPR003527 MAP kinase IPR001245 Tyrosine protein kinase 1.50703
IPR002290 Serine/threonine protein kinase IPR000719 Protein kinase 0.986464
IPR011009 Protein kinase-like IPR001781 Zn-binding protein, LIM 0.60354
IPR008271 Serine/threonine protein kinase, active site IPR001781 Zn-binding protein, LIM 0.471046
IPR011009 Protein kinase-like IPR001245 Tyrosine protein kinase 0.178275
IPR002290 Serine/threonine protein kinase IPR001781 Zn-binding protein, LIM 0.0657693
IPR000719 Protein kinase IPR001781 Zn-binding protein, LIM 0.0307996
IPR008349 ERK1/2 MAP kinase IPR001245 Tyrosine protein kinase 0.0000302204

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in LIMK1
  • Green Domain is present in both MAPK1 and LIMK1

 0.083
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: LIMK1

PTMResidueReference
Phosphorylation 508 PubMed, HPRD
Phosphothreonine 508 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: LIMK1

LocalisationReference
Golgi HPRD
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and LIMK1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andLIMK1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and LIMK1 has 1195 interactors of which there are 852 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for LIMK1-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.056
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.065
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.073
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.098
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 12.60 0.027
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.029
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.044
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 2.53 0.027
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.088
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 1.42 0.044
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 1.03 0.027
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.100
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.683 0.036
PLEK PLEK, P47: Pleckstrin 0.515 0.065
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.509 0.033
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.097
CRKL CRKL: Crk-like protein 0.461 0.097
JAK1 0.461 0.088
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.088
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.099
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.097
MSN MSN: Moesin 0.461 0.088
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.099
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.088
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 0.456 0.033
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 0.449 0.033
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.065
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.098
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.065
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 0.405 0.033
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.088
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.058
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.099
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.088
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.065
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.088
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.098
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.088
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.088
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.088
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.099
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.088
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.029
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.044
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.097
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.097
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.097
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.109
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.098
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.123
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.098
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.098
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.065
DOK1 DOK1: Docking protein 1 0.275 0.088
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.097
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.064
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.097
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.097
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.088
HCK N/A 0.275 0.088
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.097
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.088
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.056
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.097
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.098
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.037
GAB2 N/A 0.251 0.098
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.098
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.065
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.098
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.098
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.065
WASPIP N/A 0.233 0.049
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.099
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.029
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.044
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.044
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.044
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.049
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.099
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.097
SH3BP5 N/A 0.225 0.099
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.088
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.072
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.088
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.097
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.088
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.097
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.064
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.029
CCNH CCNH: Cyclin-H 0.225 0.029
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.049
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.049
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.192 0.037
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.109
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.098
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.100
CXorf9 N/A 0.188 0.097
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.099
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.099
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.029
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.065
RPS6KB1 N/A 0.188 0.050
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.088
FNBP1 N/A 0.188 0.099
GMIP GMIP: GEM-interacting protein 0.188 0.044
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.044
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.049
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.136
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.099
PSD TYL: TYL protein 0.171 0.111
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.0263
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.136
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.097
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.088
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.111
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.073
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PSCD2 N/A 0.165 0.165
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.165
BID BID: BH3-interacting domain death agonist 0.165 0.049
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.165
MAP2K5 N/A 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
ARFGAP1 N/A 0.155 0.0263
H1FX H1FX: Histone H1x 0.155 0.033
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.056
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.049
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.072
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.109
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.029
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.152
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.109
SNCB SNCB: Beta-synuclein 0.152 0.152
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.123
ETS2 ETS2: Protein C-ets-2 0.152 0.029
CREB1 CREB1: cAMP response element-binding protein 0.148 0.098
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.148
CCNT2 CCNT2: Cyclin-T2 0.148 0.044
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.165
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.044
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.148
STAT3 0.148 0.165
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
ARHGEF7 N/A 0.148 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.044
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.098
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.148
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.035
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.044
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.044
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.029
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.026
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.044
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.049
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.044
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.139 0.026
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.026
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.049
ATM ATM: Serine-protein kinase ATM 0.139 0.028
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.044
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.050
CD2AP CD2AP: CD2-associated protein 0.139 0.097
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.026
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.099
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.029
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.044
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.044
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.097
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.136
RDX RDX: Radixin 0.136 0.088
VIL2 N/A 0.136 0.088
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.136
CCNB1 Cyclin B1 0.136 0.029
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.111
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.111
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.073
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.056
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.028
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.063
RB1 RB1: Retinoblastoma-associated protein 0.127 0.037
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.055
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.055
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.055
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.0727
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.152
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.191
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.055
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.123
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.044
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.116 0.031
PGAM1 PGAM1, PGAMA, CDABP0006: Phosphoglycerate mutase 1 0.114 0.041
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.097
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.055
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.033
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.114 0.058
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.049
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.088
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.033
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.029
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.069
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.044
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.044
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.044
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.033
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.029
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.111
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.109
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.171
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.088
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 0.171
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.111 0.111
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.097
PLD2 PLD2: Phospholipase D2 0.111 0.111
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.251
BMX N/A 0.110 0.191
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.191
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.152
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.191
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.100
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.109 0.037
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.100
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.225
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.0453
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.152
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.123
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.111
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.171
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.064
PLD1 PLD1: Phospholipase D1 0.097 0.136
DAB1 DAB1: Disabled homolog 1 0.097 0.111
TST TST: Thiosulfate sulfurtransferase 0.097 0.123
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.171
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.097
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.111
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.123
NFATC1 N/A 0.096 0.032
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.062
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.032
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.049
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.026
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.039
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.096
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.032
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.123
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.065
CD44 N/A 0.091 0.033
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.090 0.029
PTPRZ1 N/A 0.090 0.073
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.033
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.171
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.171
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.049
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.029
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.064
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.056
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.044
CTPS CTPS: CTP synthase 1 0.086 0.049
RELA RELA, NFKB3: Transcription factor p65 0.086 0.033
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.049
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.049
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.086 0.086
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.086 0.033
MTA1 MTA1: Metastasis-associated protein MTA1 0.086 0.073
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.029
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.049
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.049
AHR AHR: Aryl hydrocarbon receptor precursor 0.086 0.0727
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.083
MAPKAPK5 N/A 0.083 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.083
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.049
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.083
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 0.109
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.083
MAPK15 N/A 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.049
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.083
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.028
HES6 HES6: Transcription cofactor HES-6 0.083 0.109
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.083
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.111
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.088
LCP1 LCP1, PLS2: Plastin-2 0.078 0.088
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.050
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.031
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.0308
MYB MYB: Myb proto-oncogene protein 0.077 0.032
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.049
TSPYL2 TSPYL2, CDA1, HRIHFB2216, DENTT, TSPX: Testis-specific Y-encoded-like protein 2 0.077 0.037
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.109
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.077
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.026
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.109
ATP2B1 N/A 0.075 0.037
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.065
FADD FADD, MORT1: Protein FADD 0.075 0.032
MAX MAX: Protein max 0.075 0.098
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 0.098
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.025
GIT2 N/A 0.075 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.044
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.083
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.028
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.025
SNX3 N/A 0.075 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.075
CNN2 CNN2: Calponin-2 0.075 0.165
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.098
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.044
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.098
TSC2 TSC2, TSC4: Tuberin 0.075 0.075
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.044
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.109
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.075
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.028
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.083
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.083
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.075
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.064
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.073 0.090
GABRR1 N/A 0.0727 0.100
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.100
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.026
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.032
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.049
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.029
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.055
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.056
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.034
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.070 0.034
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.056
MYCN MYCN, NMYC: N-myc proto-oncogene protein 0.069 0.064
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.069 0.064
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.111
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 13.90
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.111
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.029
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.049
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.029
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.097
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.049
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.044
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.056
BCL2L1 BCL2L1, BCL2L, BCLX: Apoptosis regulator Bcl-X 0.0688 0.034
MCL1 MCL1: Induced myeloid leukemia cell differentiation protein Mcl-1 0.0688 0.034
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 0.029
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.073
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.063 0.045
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.028
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.049
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.111
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.050
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.044
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 0.026
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.029
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.049
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.049
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.077
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.029
COBL N/A 0.062 0.077
SPTAN1 N/A 0.062 0.191
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.037
GRLF1 N/A 0.062 0.077
CHAT CHAT: Choline O-acetyltransferase 0.062 0.030
VIM VIM: Vimentin 0.060 0.033
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.064
GLRA1 N/A 0.058 0.113
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.073
PFKFB2 PFKFB2: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.057 0.057
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.057 0.072
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.057 0.029
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.081
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.069
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.062
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.086
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.056 0.073
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.056 0.037
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 0.056
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.062
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.056
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.032
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.029
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.111
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.056 0.037
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.086
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.055 0.032
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.077
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.027
TP73 TP73, P73: Tumor protein p73 0.055 0.030
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.029
EIF4EBP1 EIF4EBP1: Eukaryotic translation initiation factor 4E-binding protein 1 0.053 0.030
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.0273
RAB4A N/A 0.052 0.049
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.032
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.031
MVP MVP, LRP: Major vault protein 0.052 0.049
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.0453
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.031
LIMS1 N/A 0.052 0.049
MEF2A N/A 0.052 0.032
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.032
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.110
PSMB4 PSMB4: Proteasome subunit beta type-4 precursor 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
GRB10 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PTPRA N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.051 0.051
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.0263
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.051 0.026
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
HES1 HES1, HL, HRY: Transcription factor HES-1 0.050 0.073
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.088
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.038
CDKL5 N/A 0.049 0.032
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.049 0.081
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.049 0.049
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.04
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.109
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.049 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
AQP1 AQP1, CHIP28: Aquaporin-1 0.049 0.056
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.041
MYF5 MYF5: Myogenic factor 5 0.049 0.090
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.086
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.049 0.033
AQP2 AQP2: Aquaporin-2 0.049 0.056
GTF2A1 GTF2A1, TF2A1: Transcription initiation factor IIA subunit 1 0.049 0.041
SORBS3 SORBS3, SCAM1: Vinexin 0.049 0.111
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.037
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.062
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.048 0.062
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.077
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.075
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.044
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.075
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.044
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.044
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.029
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.039
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.050
LPXN LPXN, LDLP: Leupaxin 0.046 0.044
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.097
SRF SRF: Serum response factor 0.046 0.026
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.032
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
TH TH, TYH: Tyrosine 3-monooxygenase 0.046 0.046
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.037
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.046 0.041
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.072
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.0453 0.046
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.065
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.045 0.045
CGA CGA: Glycoprotein hormones alpha chain precursor 0.045 0.063
TSHB TSHB: Thyrotropin subunit beta precursor 0.045 0.0794
FSHB FSHB: Follitropin subunit beta precursor 0.045 0.105
LHB LHB: Lutropin subunit beta precursor 0.045 0.0794
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.045 0.045
MYO3A MYO3A: Myosin IIIA 0.044 0.069
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.056
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.062
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.029
CTTN CTTN, EMS1: Src substrate cortactin 0.044 0.191
CNN3 CNN3: Calponin-3 0.044 0.098
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.275
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.136
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.111
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.046
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.067
HAND1 HAND1, EHAND: Heart- and neural crest derivatives-expressed protein 1 0.044 0.090
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.044
AQP4 AQP4: Aquaporin-4 0.044 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.098
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.044 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.044
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.033
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.056
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.055
PDE4A N/A 0.0425 0.026
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.034
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.041 0.046
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.041
INHA INHA: Inhibin alpha chain precursor 0.041 0.051
KRT8 KRT8, CYK8: Keratin, type II cytoskeletal 8 0.041 0.031
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.041 0.051
NDP NDP: Norrin precursor 0.041 0.063
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.041 0.051
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.026
GLRB GLRB: Glycine receptor subunit beta precursor 0.041 0.033
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.032
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.090
FGF9 FGF9: Glia-activating factor precursor 0.041 0.071
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.041 0.094
TBXA2R TBXA2R: Thromboxane A2 receptor 0.04 0.04
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.04 0.04
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.026
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.026
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.086
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.039 0.077
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.077
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.038 0.026
MYH9 MYH9: Myosin-9 0.038 0.065
GMFB GMFB: Glia maturation factor beta 0.038 0.035
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.029
CFL1 CFL1, CFL: Cofilin-1 0.038 0.0308
CHP CHP: Calcium-binding protein p22 0.038 0.056
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.049
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.056
SATB1 SATB1: DNA-binding protein SATB1 0.038 0.029
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.032
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.081
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.065
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.037
GHR GHR: Growth hormone receptor precursor 0.037 0.072
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.081
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.037
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.081
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.072
RAP1GA1 N/A 0.037 0.0453
PFKFB1 N/A 0.037 0.041
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.029
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.029
CRLF3 N/A 0.036 0.0727
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.032
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.029
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.032
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.029
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.033
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.029
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.035
KRT20 KRT20: Keratin, type I cytoskeletal 20 0.034 0.0453
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.034 0.062
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.038
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.0338 0.038
TPH1 N/A 0.0338 0.038
NOS2A NOS2A, NOS2: Nitric oxide synthase, inducible 0.034 0.030
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.073
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.033 0.029
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.090
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.100
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.090
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.027
RHO RHO, OPN2: Rhodopsin 0.033 0.057
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.0453
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.072
PRLR PRLR: Prolactin receptor precursor 0.033 0.100
F3 F3: Tissue factor precursor 0.032 0.072
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.100
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.100
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.100
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.166
ITGB4 N/A 0.032 0.081
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.075
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.055
ZYX ZYX: Zyxin 0.032 0.055
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.037
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.029
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.039
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.026
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.055
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.072
RYR2 RYR2: Ryanodine receptor 2 0.031 0.051
KRT18 KRT18: Uncharacterized protein KRT18 0.031 0.0453
DES DES: Desmin 0.031 0.062
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.049
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.055
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.031 0.053
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.059
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.030 0.059
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.047
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.030 0.042
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
ABCB9 ABCB9, KIAA1520: ATP-binding cassette sub-family B member 9 precursor 0.030 0.034
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.033
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.073
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.113
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.037
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.081
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.029 0.032
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.037
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.126
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.026
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.073
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.088
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.056
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.049
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.032
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.033
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.0308
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.029 0.029
LIG1 LIG1: DNA ligase 1 0.029 0.029
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.0308
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.029
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.029 0.033
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.083
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.052
DSP DSP: Desmoplakin 0.028 0.109
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.052
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
PTPN7 N/A 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.049
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.049
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.049
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.049
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.083
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.083
AXIN1 0.028 0.052
MATK 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.052
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PPEF1 N/A 0.028 0.083
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.052
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.049
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.052
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.028 0.057
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.069
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0277 0.096
SLC2A1 SLC2A1, GLUT1: Solute carrier family 2, facilitated glucose transporter member 1 0.027 0.033
ACP1 ACP1: Protein-tyrosine-phosphatase, isoform 3 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
FAM43A N/A 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
CDC25B CDC25B, CDC25HU2: M-phase inducer phosphatase 2 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
PSMB5 PSMB5, LMPX: Proteasome subunit beta type-5 precursor 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
PSD3 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
LILRB1 N/A 0.027 0.029
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.029
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.032
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.032
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.041
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.090
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.064
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.090
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.026
DBN1 DBN1, D0S117E: Drebrin 0.026 0.034
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.037
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.062
RGS4 RGS4: Regulator of G-protein signaling 4 0.026 0.039
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.055
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.026
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.025 0.051
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.025 0.051
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.045
F5 F5: Coagulation factor V precursor 0.025 0.063
LMO6 LMO6: LIM domain only protein 6 0.025 0.075
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.083
RAD50 RAD50: DNA repair protein RAD50 0.025 0.075
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.075
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.044
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.075
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
MYO18A 0.025 0.075
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.047
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.075
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.044
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.028
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.044
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.148
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.098
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.044
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.083
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.075
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.075
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
PRKCB1 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.044
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.075
RAC1 N/A 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.028
NIPBL N/A 0.025 0.025
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 22.50
SVIL SVIL: Supervillin 0.025 0.025
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.075
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.044
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
0.299
Total Score 5.29