PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between MAPK1 and SMAD3

The interaction score between MAPK1 and SMAD3 is 10.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between MAPK1 and SMAD3 = 0.27

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

2.88E-3

Orthology

Organism	MAPK1 Orthologue		SMAD3 Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
worm	P39745	1	Q02330	0.219
fly	P40417	1	O96660	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in MAPK1 and SMAD3:

Domains in MAPK1

Domains in SMAD3

IPR000719	Protein kinase
IPR002290	Serine/threonine protein kinase
IPR011009	Protein kinase-like
IPR008271	Serine/threonine protein kinase, active site
IPR003527	MAP kinase
IPR008349	ERK1/2 MAP kinase

IPR008984	SMAD/FHA
IPR003619	Dwarfin protein, domain A
IPR001132	Dwarfin protein
IPR013019	MAD_MH1.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and SMAD3 are listed below.

Domain 1		Domain 2		Chi Square
IPR011009	Protein kinase-like	IPR003619	Dwarfin protein, domain A	12.3099
IPR011009	Protein kinase-like	IPR013019	MAD_MH1.	12.1698
IPR011009	Protein kinase-like	IPR001132	Dwarfin protein	12.1698
IPR000719	Protein kinase	IPR003619	Dwarfin protein, domain A	6.02148
IPR000719	Protein kinase	IPR001132	Dwarfin protein	5.86622
IPR000719	Protein kinase	IPR013019	MAD_MH1.	5.86622
IPR000719	Protein kinase	IPR008984	SMAD/FHA	5.66869
IPR002290	Serine/threonine protein kinase	IPR003619	Dwarfin protein, domain A	2.38964
IPR002290	Serine/threonine protein kinase	IPR013019	MAD_MH1.	2.3306
IPR002290	Serine/threonine protein kinase	IPR001132	Dwarfin protein	2.3306
IPR002290	Serine/threonine protein kinase	IPR008984	SMAD/FHA	1.57901
IPR008271	Serine/threonine protein kinase, active site	IPR008984	SMAD/FHA	0.0640665
IPR008271	Serine/threonine protein kinase, active site	IPR003619	Dwarfin protein, domain A	0.0575769
IPR008271	Serine/threonine protein kinase, active site	IPR001132	Dwarfin protein	0.0449629
IPR008271	Serine/threonine protein kinase, active site	IPR013019	MAD_MH1.	0.0449629

The background colour of the table refers to:

Blue Domain is only present in MAPK1
Yellow Domain is only present in SMAD3
Green Domain is present in both MAPK1 and SMAD3

0.083

Post-translational Modifications

Protein: MAPK1

PTM	Residue	Reference
Acetylation	2	PubMed, HPRD
Dephosphorylation	187	PubMed, HPRD
N-acetylalanine	1	HPRD
Phosphorylation	29	PubMed, HPRD
Phosphorylation	41	PubMed, HPRD
Phosphorylation	181	PubMed, HPRD
Phosphorylation	185	PubMed, HPRD
Phosphorylation	187	PubMed, HPRD
Phosphorylation	202	PubMed, HPRD
Phosphothreonine	184	PubMed, HPRD
Phosphotyrosine	186	HPRD

Protein: SMAD3

PTM	Residue	Reference
Phosphorylation	8	PubMed, HPRD
Phosphorylation	179	PubMed, HPRD
Phosphorylation	204	PubMed, HPRD
Phosphorylation	208	PubMed, HPRD
Phosphorylation	213	PubMed, HPRD
Phosphorylation	422	PubMed, HPRD
Phosphorylation	423	PubMed, HPRD
Phosphorylation	425	PubMed, HPRD

Localisation

Protein: MAPK1

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Protein: SMAD3

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between MAPK1 and SMAD3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andSMAD3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and SMAD3 has 962 interactors of which there are 772 common interactors.

Common Interactor	Name of Common Interactor	Score for MAPK1-Interactor (?)	Score for SMAD3-Interactor (?)
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	153.00	26.80
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	115.00	0.038
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	94.70	0.046
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	62.30	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	62.30	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	62.30	0.025
DIAPH1	Diaphanous 1	20.60	0.038
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	11.60	0.038
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	7.38	0.046
CDK2	CDK2: Cell division protein kinase 2	6.80	0.029
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	4.15	0.046
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	2.17	0.046
PLEK	PLEK, P47: Pleckstrin	0.515	0.052
COPS5	COPS5, CSN5, JAB1: COP9 signalosome complex subunit 5	0.475	0.414
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.461	0.029
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.461	0.038
VAV1	VAV1, VAV: Proto-oncogene vav	0.461	0.111
ID2	ID2: DNA-binding protein inhibitor ID-2	0.430	0.032
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	0.416	0.027
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.416	0.127
ELF1	ELF1: ETS-related transcription factor Elf-1	0.416	0.210
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.416	0.127
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.385	0.046
STK10	STK10: Uncharacterized protein STK10	0.385	0.046
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	0.385	0.0818
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.372	0.087
STAT6	STAT6: Signal transducer and activator of transcription 6	0.372	0.032
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.372	0.114
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.372	0.0818
CSK	CSK: Tyrosine-protein kinase CSK	0.372	0.032
JUND	JUND: Transcription factor jun-D	0.372	0.114
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.372	0.038
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.344	0.046
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.307	0.0425
ROCK1	ROCK1: Rho-associated protein kinase 1	0.307	0.052
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.307	0.0425
DOK1	DOK1: Docking protein 1	0.275	0.046
JUNB	JUNB: Transcription factor jun-B	0.275	0.139
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.275	0.029
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.275	0.038
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.275	0.063
MAFG	MAFG: Transcription factor MafG	0.275	0.069
ETS1	ETS1, EWSR2: Protein C-ets-1	0.275	0.139
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.275	0.086
GAB2	N/A	0.251	0.026
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.251	0.052
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.251	0.075
BACH1	BACH1: Transcription regulator protein BACH1	0.251	0.127
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.233	0.114
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.233	0.032
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.233	0.046
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.233	0.114
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.233	0.046
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.233	0.046
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.233	0.038
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.233	0.038
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.233	66.70
JUN	JUN: Transcription factor AP-1	0.225	0.086
ATF6	ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha	0.225	0.114
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.225	0.063
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.225	0.114
SOS1	SOS1: Son of sevenless homolog 1	0.225	0.071
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.225	0.139
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.210	0.210
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.210	0.052
CFLAR	CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec	0.210	0.027
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.210	0.0971
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.210	0.070
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.208	0.208
TGFB1	TGFB1, TGFB: Transforming growth factor beta-1 precursor	0.192	0.076
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.191	0.032
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.191	0.027
STAT2	STAT2: Signal transducer and activator of transcription 2	0.191	0.0425
CXorf9	N/A	0.188	0.139
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.188	0.032
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.188	0.139
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.188	0.038
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.188	0.038
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.188	0.063
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.188	0.118
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.188	0.087
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.188	0.038
RPS6KB1	N/A	0.188	0.046
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.188	0.029
FNBP1	N/A	0.188	0.046
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.174	0.028
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.171	0.086
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.171	0.033
PRKCI	PRKCI, DXS1179E: Protein kinase C iota type	0.171	0.051
NSBP1	NSBP1: Nucleosome-binding protein 1	0.165	0.028
BID	BID: BH3-interacting domain death agonist	0.165	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.165	0.083
MAP2K5	N/A	0.165	0.049
NF2	NF2, SCH: Merlin	0.165	0.028
ARFGAP1	N/A	0.155	0.052
HD	HD, IT15: Huntingtin	0.155	0.061
H1FX	H1FX: Histone H1x	0.155	0.096
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.155	0.032
TRADD	TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein	0.155	0.036
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.155	0.032
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.155	0.026
ERF	ERF: ETS domain-containing transcription factor ERF	0.152	0.127
GAB1	GAB1: GRB2-associated-binding protein 1	0.152	0.032
ETS2	ETS2: Protein C-ets-2	0.152	0.077
CREB1	CREB1: cAMP response element-binding protein	0.148	0.075
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.148	0.025
CCNT2	CCNT2: Cyclin-T2	0.148	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.148	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.148	0.025
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.148	0.044
EEF2K	EEF2K: Elongation factor 2 kinase	0.148	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.148	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.148	0.025
ELMO1	N/A	0.148	0.025
ARHGEF7	N/A	0.148	6.17
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.148	0.036
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.148	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.148	0.025
PARD6A	PARD6A, PAR6A: Partitioning defective 6 homolog alpha	0.148	0.044
RAP1A	RAP1A, KREV1: Ras-related protein Rap-1A precursor	0.146	0.148
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.146	0.181
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.139	0.046
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.139	0.046
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.139	0.038
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.139	0.046
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.139	0.038
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.139	0.038
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.139	0.046
ATM	ATM: Serine-protein kinase ATM	0.139	0.114
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.139	0.114
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.139	0.046
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.139	0.114
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.139	0.067
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.139	0.054
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.139	0.038
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.025
PRKCZ	PRKCZ, PKC2: Protein kinase C zeta type	0.136	0.029
FOSL2	FOSL2, FRA2: Fos-related antigen 2	0.136	0.086
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.136	0.086
TIAM1	TIAM1: T-lymphoma invasion and metastasis-inducing protein 1	0.136	0.028
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.132	0.274
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.129	0.038
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.129	0.038
RB1	RB1: Retinoblastoma-associated protein	0.127	0.060
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.127	0.0425
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.127	0.070
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.127	0.032
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.127	0.052
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.127	0.032
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.127	0.032
ERG	ERG: Transcriptional regulator ERG	0.123	0.062
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.123	0.032
SQSTM1	SQSTM1: Uncharacterized protein SQSTM1	0.123	0.057
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.118	0.086
PPP1R8	N/A	0.118	0.114
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.118	0.139
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.118	0.148
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.114	0.038
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.114	0.046
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.114	0.029
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.114	0.111
EIF4G3	EIF4G3: Eukaryotic translation initiation factor 4 gamma 3	0.114	0.054
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.114	0.139
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.114	0.056
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.114	0.038
SGK	SGK, SGK1: Serine/threonine-protein kinase Sgk1	0.114	0.029
RPS10	RPS10: 40S ribosomal protein S10	0.114	0.032
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.114	0.038
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.114	0.086
EDD1	EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1	0.113	0.094
ELK1	ELK1: ETS domain-containing protein Elk-1	0.111	0.049
CEBPE	CEBPE: CCAAT/enhancer-binding protein epsilon	0.111	0.056
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.109	0.055
MCF2	MCF2, DBL: Proto-oncogene DBL	0.109	0.0263
ARHGEF12	ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12	0.109	0.0277
HMGA2	HMGA2, HMGIC: High mobility group protein HMGI-C	0.109	0.026
ETV1	ETV1, ER81: ETS translocation variant 1	0.098	0.049
IRS1	IRS1: Insulin receptor substrate 1	0.098	0.026
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.097	0.043
DAB1	DAB1: Disabled homolog 1	0.097	7.14
PTMA	N/A	0.0971	0.052
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.0971	0.127
NBN	NBN, NBS, NBS1, P95: Nibrin	0.0971	0.155
SP100	N/A	0.0971	0.210
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.096	0.152
NFATC1	N/A	0.096	0.070
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.096	0.052
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.096	0.027
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.096	0.032
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.096	0.096
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.096	0.062
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.096	0.052
SMAD7	SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7	0.096	0.062
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.087	0.032
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.087	0.0425
MATR3	MATR3, KIAA0723: Matrin-3	0.087	0.096
IFI16	N/A	0.087	0.070
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.087	0.114
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.087	0.029
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.086	0.029
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.086	0.038
CDK7	CDK7, MO15: Cell division protein kinase 7	0.086	0.038
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.086	0.038
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.086	0.029
RELA	RELA, NFKB3: Transcription factor p65	0.086	0.046
MTA1	MTA1: Metastasis-associated protein MTA1	0.086	0.038
SMAD4	SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4	0.086	0.114
NPM1	NPM1, NPM: Nucleophosmin	0.086	0.029
TP53	TP53, P53: Cellular tumor antigen p53	0.086	0.087
AHR	AHR: Aryl hydrocarbon receptor precursor	0.086	0.029
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.083	0.049
MAPKAPK5	N/A	0.083	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.083	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.083
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.083	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.083	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.083	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.083	0.028
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.083	0.049
MAPK15	N/A	0.083	0.083
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.083	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.083	0.028
HES6	HES6: Transcription cofactor HES-6	0.083	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.083	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.083	0.028
IRF3	IRF3: Interferon regulatory factor 3	0.080	0.155
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.078	0.087
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.078	0.067
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.078	0.046
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.078	0.046
LCP1	LCP1, PLS2: Plastin-2	0.078	0.067
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.078	19.50
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.078	0.029
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.078	0.038
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.078	0.038
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.078	0.046
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.078	0.046
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.078	0.046
KIAA1012	KIAA1012: Protein TRS85 homolog	0.078	0.063
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.078	0.063
KLHDC4	N/A	0.078	0.038
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.078	0.086
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.078	0.114
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.046
NEK3	NEK3: Serine/threonine-protein kinase Nek3	0.077	0.026
MYB	MYB: Myb proto-oncogene protein	0.077	0.062
PRKAA1	N/A	0.077	0.032
STK16	N/A	0.077	0.0425
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.077	0.075
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.077	0.026
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.077	0.026
MAX	MAX: Protein max	0.075	0.025
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.075	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.075	0.025
GIT2	N/A	0.075	0.025
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.075	0.075
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.075	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.075	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.075	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.075	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.075	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.075	0.047
CNN2	CNN2: Calponin-2	0.075	0.049
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.075	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.075	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.075	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.075	0.075
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.075	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.075	0.047
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.075	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.075	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.075	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.075	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.075	0.047
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.075	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.075	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.075	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.075	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.075	35.90
CDC2	CDC2: Cell division control protein 2 homolog	0.075	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.075	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.075	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.075	0.028
CDC42	CDC42: Cell division control protein 42 homolog precursor	0.073	0.067
SLC4A1AP	SLC4A1AP: Uncharacterized protein SLC4A1AP	0.071	0.069
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.071	0.029
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.071	0.113
MCM3	MCM3: DNA replication licensing factor MCM3	0.071	0.029
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.071	0.069
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.052
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.070	0.210
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.070	0.087
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.070	0.0425
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.070	0.0425
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.032
GTF3C1	N/A	0.070	0.026
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.070	0.052
KIAA0853	N/A	0.070	0.052
ABCF1	N/A	0.070	0.0425
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.070	0.052
TOP2B	N/A	0.070	0.032
IFI35	N/A	0.070	0.036
WDR1	N/A	0.070	0.210
MARK2	N/A	0.070	0.052
RGS14	N/A	0.070	0.052
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.070	0.0425
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.052
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.070	0.0425
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.069	0.056
PRKG1	PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme	0.069	0.056
VDR	VDR, NR1I1: Vitamin D3 receptor	0.069	0.086
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.069	0.035
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.069	0.056
CDC20	CDC20: Cell division cycle protein 20 homolog	0.069	0.056
MAP2K6	MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki	0.069	0.029
PSKH1	PSKH1: Serine/threonine-protein kinase H1	0.069	0.038
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.069	0.038
CDK4	CDK4: Cell division protein kinase 4	0.069	0.029
GSK3B	N/A	0.063	0.038
CUL4B	N/A	0.063	0.046
COPA	COPA: Coatomer subunit alpha	0.063	0.188
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.063	0.029
ACTG1	ACTB: Actin, cytoplasmic 1	0.063	0.032
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.063	0.038
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.063	0.114
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.063	0.038
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.046
DPF2	DPF2, REQ, UBID4: Zinc finger protein ubi-d4	0.063	0.067
NUP153	N/A	0.063	0.029
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.038
MAD1L1	MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1	0.063	0.032
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.063	0.188
MAPRE2	MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2	0.063	0.027
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.063	0.136
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.063	0.038
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.063	0.029
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.063	0.029
CUL5	CUL5, VACM1: Cullin-5	0.063	0.038
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.063	0.038
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.063	0.046
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.063	0.046
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.063	0.087
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.046
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	0.063	0.063
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.063	0.114
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.063	0.046
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.063	0.046
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.063	0.038
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.063	0.071
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.063	0.139
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.063	0.046
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.063	0.114
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.063	0.139
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.063	0.038
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.063	0.046
EP300	N/A	0.063	0.038
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.063	0.139
YY1	YY1: Transcriptional repressor protein YY1	0.063	0.139
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.063	0.038
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.063	0.038
TIAL1	TIAL1: Nucleolysin TIAR	0.063	0.038
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.063	0.188
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.062	0.096
GRLF1	N/A	0.062	0.152
GTF2F2	N/A	0.060	0.127
VIM	VIM: Vimentin	0.060	0.070
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.060	0.191
RERE	RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei	0.056	0.069
TERT	TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase	0.056	0.026
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.056	0.051
NR1D1	NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1	0.056	0.044
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.055	0.0425
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.055	0.062
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.055	0.026
TP73	TP73, P73: Tumor protein p73	0.055	0.055
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.054	0.097
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.083
RAB4A	N/A	0.052	0.165
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.165
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.052	0.155
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.052	0.077
CHUK	N/A	0.052	0.032
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.052	0.070
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.052	0.052
FUBP1	N/A	0.052	0.027
MVP	MVP, LRP: Major vault protein	0.052	0.027
NCOA3	N/A	0.052	0.087
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.052	0.096
SET	SET: Protein SET	0.052	0.0425
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.052	0.060
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.052	0.032
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.052	0.052
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.052	0.032
RBM14	RBM14, SIP: RNA-binding protein 14	0.052	0.0425
LIMS1	N/A	0.052	0.027
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.052	0.052
MEF2A	N/A	0.052	0.096
API5	N/A	0.052	0.032
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.052	0.127
DDX21	DDX21: Nucleolar RNA helicase 2	0.052	0.052
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.052	0.049
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.052	0.032
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.052	0.0425
FLNA	FLNA, FLN, FLN1: Filamin-A	0.052	0.074
SRPR	SRPR: Uncharacterized protein SRPR	0.052	0.036
TGFBR2	TGFBR2: TGF-beta receptor type-2 precursor	0.051	0.114
TAGLN	TAGLN, SM22, WS3-10: Transgelin	0.050	0.041
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.049	0.032
NFIB	N/A	0.049	0.077
DAPK2	DAPK2: Death-associated protein kinase 2	0.049	0.026
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.049	0.056
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.049	0.086
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	0.049	0.069
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.048	0.062
MKI67	MKI67: Antigen KI-67	0.048	0.077
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.047	0.025
SOX8	SOX8: Transcription factor SOX-8	0.047	0.075
RAB5B	RAB5B: Ras-related protein Rab-5B	0.047	0.098
LMNA	LMNA, LMN1: Lamin-A/C	0.047	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.075
HDAC3	HDAC3: Histone deacetylase 3	0.046	0.038
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.046	0.046
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.046	0.148
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.046	0.029
SP3	SP3: Transcription factor Sp3	0.046	0.086
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.046	0.038
QARS	QARS: Glutaminyl-tRNA synthetase	0.046	0.032
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.046	0.029
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.046	0.038
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.046	0.046
SSB	SSB: Lupus La protein	0.046	0.038
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.046	0.038
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.046	0.063
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.046	0.038
CORO1C	CORO1C, CRNN4: Coronin-1C	0.046	0.139
BRPF1	BRPF1, BR140: Peregrin	0.046	0.086
MTF1	MTF1: Metal regulatory transcription factor 1	0.046	54.60
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.046	0.038
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.046	0.054
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.046	0.038
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.046	0.046
XPO1	XPO1, CRM1: Exportin-1	0.046	0.054
FLII	FLII, FLIL: Protein flightless-1 homolog	0.046	0.032
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.038
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.046	0.038
PCAF	PCAF: Histone acetyltransferase PCAF	0.046	0.049
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.029
SEC31L1	N/A	0.046	0.188
LPXN	LPXN, LDLP: Leupaxin	0.046	0.032
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.046	0.114
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.046	0.087
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.046	0.035
COPE	COPE: Coatomer subunit epsilon	0.046	0.038
CBX3	CBX3: Chromobox protein homolog 3	0.046	0.038
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.046	0.046
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.046	0.029
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.046	0.032
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.046	0.029
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.046	0.038
SAPS3	N/A	0.046	0.046
SRF	SRF: Serum response factor	0.046	0.139
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.046	0.029
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.046	0.038
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.046	0.032
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.046	0.069
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.046	0.114
WDR44	WDR44: WD repeat-containing protein 44	0.046	0.038
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.046	0.038
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.046	0.029
CNN3	CNN3: Calponin-3	0.044	0.029
DNMBP	DNMBP, KIAA1010: Dynamin-binding protein	0.044	0.041
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.044	0.086
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.044	0.055
ACVR1B	ACVR1B, ACVRLK4: Activin receptor type-1B precursor	0.044	29.60
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.043	0.056
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.043	0.069
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.043	0.069
SOX4	SOX4: Transcription factor SOX-4	0.043	0.069
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.0425	0.032
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.0425	0.096
DAPP1	N/A	0.0425	0.027
MPG	N/A	0.0425	0.027
GNB2L1	Lung cancer oncogene 7	0.0425	0.210
SH3BP3		0.0425	0.077
SMARCC2	N/A	0.0425	0.032
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.0425	0.032
XRCC1	XRCC1: DNA-repair protein XRCC1	0.0425	0.032
ZNF267	ZNF267: Zinc finger protein 267	0.0425	0.077
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.0425	0.026
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.0425	0.0425
TCOF1	N/A	0.0425	0.0425
NUP214	N/A	0.0425	0.096
SREBF2	N/A	0.0425	0.0425
DNMT1	DNMT1, AIM, DNMT: DNA	0.0425	0.032
CAMK2D	CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain	0.040	7.92
RAC2	RAC2: Ras-related C3 botulinum toxin substrate 2 precursor	0.039	0.100
RAB8A	RAB8A: RAB8A protein	0.039	0.093
RAB5A	RAB5A, RAB5: Ras-related protein Rab-5A	0.039	0.060
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.038	0.029
HDAC2	HDAC2: Histone deacetylase 2	0.038	0.029
KCTD12	KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12	0.038	0.029
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.038	0.029
RPL8	RPL8: 60S ribosomal protein L8	0.038	0.032
MYH9	MYH9: Myosin-9	0.038	0.046
ZFP36	ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline	0.038	0.029
PHF10	N/A	0.038	0.038
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.038	0.046
COPB2	COPB2: Coatomer subunit beta'	0.038	0.139
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.038	0.046
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	0.038	0.032
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.038	0.038
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.038	0.069
CDC34	CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1	0.038	0.033
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.038	0.038
CREBBP	CREBBP, CBP: CREB-binding protein	0.038	41.40
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.038	0.029
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.038	0.038
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.038	0.032
ZNF335	ZNF335: Zinc finger protein 335	0.038	0.114
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.038	0.038
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.038	0.086
ZFYVE16	ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16	0.038	0.049
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.038	0.114
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.038	0.038
WBSCR20A	N/A	0.038	0.046
DYNC1I2	N/A	0.038	0.056
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.114
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.038	0.046
EEF1B2	EEF1B2, EEF1B, EF1B: Elongation factor 1-beta	0.038	0.032
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.038	0.046
GMCL1L	GMCL1L, GCL: Germ cell-less protein-like 1-like	0.038	13.90
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.038	0.029
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.038	0.038
NOL1	N/A	0.038	0.038
MDN1	MDN1, KIAA0301: Midasin	0.038	0.029
EEF2	EEF2, EF2: Elongation factor 2	0.038	0.245
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.038	0.038
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.029
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.038	0.114
TPT1	TPT1: Translationally-controlled tumor protein	0.038	0.032
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.038	0.139
SATB1	SATB1: DNA-binding protein SATB1	0.038	0.069
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.038	0.032
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.038	0.038
RHOG	RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor	0.0354	0.067
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.035	0.225
LEF1	LEF1: Lymphoid enhancer-binding factor 1	0.035	0.049
TGFBR1	TGFBR1: TGF-beta receptor type-1 precursor	0.033	27.30
RBM6	RBM6, DEF3: RNA-binding protein 6	0.032	0.0425
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.032	0.077
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.032	0.0425
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.096
UBAP2	N/A	0.032	0.026
AFF1	N/A	0.032	0.032
XRCC4	N/A	0.032	0.032
ZFX	ZFX: Zinc finger X-chromosomal protein	0.032	0.155
TGIF2	TGIF2: Homeobox protein TGIF2	0.032	0.210
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.032	0.060
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.032	0.048
NAT1	NAT1, AAC1: Arylamine N-acetyltransferase 1	0.032	0.027
COIL	COIL, CLN80: Coilin	0.032	0.032
HIVEP1	N/A	0.032	0.127
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.0425
CUL2	CUL2: Cullin-2	0.032	0.027
RRAS	RRAS: Ras-related protein R-Ras precursor	0.0308	0.148
RHOB	RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor	0.0308	0.072
SOX11	SOX11: Transcription factor SOX-11	0.0308	0.049
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.029	0.029
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.029	0.038
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.029	0.046
EHBP1	EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1	0.029	0.027
RBM7		0.029	0.038
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.114
WWOX	WWOX, FOR, WOX1: WW domain-containing oxidoreductase	0.029	0.029
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.029	0.038
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.029	0.038
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.029	0.029
SP1	SP1, TSFP1: Transcription factor Sp1	0.029	0.069
MYBL2	MYBL2, BMYB: Myb-related protein B	0.029	0.056
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.029	0.086
ZNF224	ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224	0.029	0.086
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.029	0.046
RCP9	CRCP: DNA-directed RNA polymerase III subunit RPC9	0.029	0.029
POLA2	POLA2: DNA polymerase subunit alpha B	0.029	0.038
SIRT1	SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1	0.029	0.029
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.029	0.038
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.029	0.114
SYMPK	SYMPK, SPK: Symplekin	0.029	0.054
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.029	0.041
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.029	0.114
RUNX1	N/A	0.029	13.90
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.029	0.029
TRIM25	TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25	0.029	0.038
AIP	AIP, XAP2: AH receptor-interacting protein	0.029	0.038
FZR1	N/A	0.029	0.029
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.029	0.114
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.029	0.029
ZBTB40	ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40	0.029	0.114
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.029	0.069
DUSP22	DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22	0.029	0.038
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.029	0.038
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.029	0.029
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.029	0.038
BCDO2	PTS: 6-pyruvoyl tetrahydrobiopterin synthase	0.029	0.056
KIAA0690	N/A	0.029	0.054
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
IRF7	N/A	0.028	0.028
C13orf8	N/A	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
WDR54	N/A	0.028	0.083
C20orf18	N/A	0.028	0.052
DSP	DSP: Desmoplakin	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.083
CABLES1	N/A	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
SNRPB	N/A	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.165
ZNF265	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.083
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.083
HDAC8	N/A	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.083
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.028	0.083
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.083
DUSP15	N/A	0.028	0.028
AXIN1		0.028	0.049
UHRF1		0.028	0.052
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.083
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
PHLDB2	N/A	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.083
PPEF1	N/A	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
KIF1B	N/A	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
CORO6	N/A	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.083
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.083
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.083
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.028
KRAS	N/A	0.0278	0.032
FOXL2	FOXL2: Forkhead box protein L2	0.028	0.097
RRAD	RRAD, RAD: GTP-binding protein RAD	0.028	0.111
RFX1	RFX1: MHC class II regulatory factor RFX1	0.028	0.049
TRRAP	N/A	0.026	0.032
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.026	0.052
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.062
AFAP	AFAP1, AFAP: Actin filament-associated protein 1	0.026	0.026
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.026	0.026
ZBTB33	KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso	0.026	0.096
CENPA	CENPA: Histone H3-like centromeric protein A	0.026	0.026
EMD	EMD, EDMD, STA: Emerin	0.026	0.032
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.032
PHB2	PHB2, BAP, REA: Prohibitin-2	0.026	0.027
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.026	0.096
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.026	0.026
KIF23	N/A	0.026	0.026
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.026	0.026
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.075
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.025	0.148
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.075
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.075
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.148
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.075
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
TCEA1	N/A	0.025	0.025
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.075
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.075
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
HTATIP	N/A	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.075
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
SEC13L1	N/A	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
C20orf77	N/A	0.025	0.025
ACTN4	ACTN4: Alpha-actinin-4	0.025	0.036
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
BRD4	N/A	0.025	0.047
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.075
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
BCOR	N/A	0.025	0.025
MAP2K3	N/A	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.025	0.044
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.075
GRK6	N/A	0.025	0.025
NUP98	N/A	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
RASD1	RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor	0.025	0.098
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
RNF20		0.025	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.075
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
SON		0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
RAB1B	RAB1B: Ras-related protein Rab-1B	0.025	0.050
PRKCB1	N/A	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.075
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
ATXN2L	N/A	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
FLJ23436	N/A	0.025	0.025
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
NIPBL	N/A	0.025	0.047
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
CAMK2A	N/A	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
NES	N/A	0.025	0.028
KCTD1		0.025	0.025
HDAC7A	N/A	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.025
DIDO1	N/A	0.025	0.025
CAMKK1	N/A	0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.075
KIAA0031	EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component	0.025	0.098
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.075
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025

0.299

Total Score

10.30