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Evidence of Interaction Between MAPK1 and MAFG

The interaction score between MAPK1 and MAFG is 32.80.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and MAFG = 0.45

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 4.62E-3
Orthology
OrganismMAPK1 OrthologueMAFG OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly P40417 1 Q9V958 0.59

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and MAFG:
Domains in MAPK1Domains in MAFG
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR004826 Maf transcription factor

The Chi square scores for co-occurrence of domains that are present in MAPK1 and MAFG are listed below.

Domain 1Domain 2Chi Square
IPR011009 Protein kinase-like IPR004827 Basic-leucine zipper (bZIP) transcription factor 9.23719
IPR000719 Protein kinase IPR004827 Basic-leucine zipper (bZIP) transcription factor 8.28186
IPR011009 Protein kinase-like IPR008917 Eukaryotic transcription factor, DNA-binding 5.70607
IPR003527 MAP kinase IPR008917 Eukaryotic transcription factor, DNA-binding 5.24231
IPR000719 Protein kinase IPR008917 Eukaryotic transcription factor, DNA-binding 3.61835
IPR003527 MAP kinase IPR004827 Basic-leucine zipper (bZIP) transcription factor 1.58426
IPR002290 Serine/threonine protein kinase IPR008917 Eukaryotic transcription factor, DNA-binding 0.250234
IPR008271 Serine/threonine protein kinase, active site IPR008917 Eukaryotic transcription factor, DNA-binding 0.186644
IPR008271 Serine/threonine protein kinase, active site IPR004827 Basic-leucine zipper (bZIP) transcription factor 0.00153394
IPR002290 Serine/threonine protein kinase IPR004827 Basic-leucine zipper (bZIP) transcription factor 0.000586009

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in MAFG
  • Green Domain is present in both MAPK1 and MAFG

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: MAFG

PTMResidueReference
Acetylation 53 PubMed, HPRD
Acetylation 60 PubMed, HPRD
Acetylation 71 PubMed, HPRD
Acetylation 76 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: MAFG

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between MAPK1 and MAFG that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andMAFG. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and MAFG has 870 interactors of which there are 723 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for MAFG-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.136
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.038
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.025
DIAPH1 Diaphanous 1 20.60 0.038
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.063
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.029
CDK2 CDK2: Cell division protein kinase 2 6.80 0.071
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.063
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.032
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.029
PLEK PLEK, P47: Pleckstrin 0.515 0.032
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.060
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 1.50
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.251
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.077
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.087
STK10 STK10: Uncharacterized protein STK10 0.385 0.043
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.054
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.051
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 2.94
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.040
JUND JUND: Transcription factor jun-D 0.372 2.94
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.139
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.046
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.026
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.077
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.070
DOK1 DOK1: Docking protein 1 0.275 0.029
JUNB JUNB: Transcription factor jun-B 0.275 1.78
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.086
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.114
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.086
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.111
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 0.275
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.054
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.0425
BACH1 BACH1: Transcription regulator protein BACH1 0.251 1.20
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.052
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.087
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.046
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.029
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.118
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.086
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.071
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.114
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.114
JUN JUN: Transcription factor AP-1 0.225 2.17
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.051
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.225 0.869
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.049
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.035
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 1.35
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.225
CCNH CCNH: Cyclin-H 0.225 0.086
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.026
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.060
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.096
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.127
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.216
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.077
CXorf9 N/A 0.188 0.069
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.093
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.188
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.087
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.043
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.046
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.139
RPS6KB1 N/A 0.188 0.114
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.114
FNBP1 N/A 0.188 0.029
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.052
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.123
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.041
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.028
ARFGAP1 N/A 0.155 0.0425
H1FX H1FX: Histone H1x 0.155 0.307
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.060
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.080
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.152
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.026
ETS2 ETS2: Protein C-ets-2 0.152 0.307
CREB1 CREB1: cAMP response element-binding protein 0.148 1.17
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
CCNT2 CCNT2: Cyclin-T2 0.148 0.075
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.075
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.028
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.075
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.047
ELMO1 N/A 0.148 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.075
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.075
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.071
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.029
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.086
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.063
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.139
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.063
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.118
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.043
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.035
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.029
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.139
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.067
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.171
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.056
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.188
ELF4 ELF4, ELFR, MEF: ETS-related transcription factor Elf-4 0.137 0.041
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.047
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
CCNB1 Cyclin B1 0.136 0.139
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.033
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.136 0.111
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.136 0.225
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.027
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.029
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.129 0.046
RB1 RB1: Retinoblastoma-associated protein 0.127 0.127
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.087
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.048
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.048
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.026
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.048
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.060
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.127 0.210
ERG ERG: Transcriptional regulator ERG 0.123 0.191
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.032
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.057
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.136
PPP1R8 N/A 0.118 0.046
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.372
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.063
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.026
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.029
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.114 0.054
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.136
CDK5 CDK5: Cell division protein kinase 5 0.114 0.054
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.029
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.136
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.038
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.071
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.114
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.114 0.136
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.087
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.097
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.029
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.111 0.111
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.034
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.026
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.109 0.039
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.098
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.049
PTMA N/A 0.0971 0.070
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.096
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.096
SP100 N/A 0.0971 0.127
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.0425
NFATC1 N/A 0.096 0.077
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.052
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.039
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.032
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.032
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.032
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.026
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.049
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.052
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.056
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.052
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.0425
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.080
IFI16 N/A 0.087 0.032
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.139
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.038
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.087
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.049
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.054
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.027
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.056
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.071
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.069
RELA RELA, NFKB3: Transcription factor p65 0.086 0.056
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.046
MTA1 MTA1: Metastasis-associated protein MTA1 0.086 0.054
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.056
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.029
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.056
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.038
AHR AHR: Aryl hydrocarbon receptor precursor 0.086 0.0971
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.038
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.109
MAPKAPK5 N/A 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 0.052
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.052
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.109
MAPK15 N/A 0.083 0.165
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
HES6 HES6: Transcription cofactor HES-6 0.083 0.052
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.152
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.038
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.063
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.078 0.029
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.032
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.0425
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.038
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.063
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.078 0.038
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.078 0.114
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.078 0.046
HNRPK N/A 0.078 0.032
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.038
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.046
KLHDC4 N/A 0.078 0.038
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.078 0.118
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.078 0.046
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.046
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.060
MYB MYB: Myb proto-oncogene protein 0.077 0.191
PRKAA1 N/A 0.077 0.039
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.100
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.048
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.039
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.036
MAX MAX: Protein max 0.075 0.047
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 0.047
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.025
GIT2 N/A 0.075 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.047
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.047
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.047
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.052
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.047
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.047
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.047
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.047
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.036
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.047
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.052
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.047
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.047
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.047
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.075
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.075
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.052
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.083
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.083
FLI1 FLI1: Friend leukemia integration 1 transcription factor 0.074 0.028
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.046
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.032
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.046
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.063
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.188
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.127
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.0971
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.052
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.052
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.032
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.070
GTF3C1 N/A 0.070 0.032
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.0425
KIAA0853 N/A 0.070 0.052
ABCF1 N/A 0.070 0.0425
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.052
TOP2B N/A 0.070 0.0425
WDR1 N/A 0.070 0.032
MARK2 N/A 0.070 0.032
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.052
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.0425
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.0425
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.069
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.069
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.035
MYCN MYCN, NMYC: N-myc proto-oncogene protein 0.069 0.054
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.069 0.118
VDR VDR, NR1I1: Vitamin D3 receptor 0.069 0.086
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.071
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.0308
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.069 0.086
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.046
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.035
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.054
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.043
CDK4 CDK4: Cell division protein kinase 4 0.069 0.071
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.054
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.026
GSK3B N/A 0.063 0.046
COPA COPA: Coatomer subunit alpha 0.063 0.046
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.063 0.063
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.032
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.038
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.046
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.038
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.0818
NUP153 N/A 0.063 0.046
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.038
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.038
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.032
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.038
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.063
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.063 0.038
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.139
CUL5 CUL5, VACM1: Cullin-5 0.063 0.046
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 0.063
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.078
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.063
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.046
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.029
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.029
EXOC2 N/A 0.063 0.041
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.118
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.046
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.063
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.063 0.275
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.087
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.038
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.171
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.046
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.046
EP300 N/A 0.063 0.078
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.087
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.118
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.046
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.063 0.038
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.039
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.060
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.123
GTF2F2 N/A 0.060 0.191
VIM VIM: Vimentin 0.060 0.026
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.191
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.028
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.0308
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.056 0.111
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.071
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.056 0.056
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.034
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.064
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.039
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.056 0.049
WEE1 WEE1: Wee1-like protein kinase 0.056 0.029
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.055 0.026
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.055
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.098
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.055 0.077
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.063
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.461
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.165
RAB4A N/A 0.052 0.028
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.165
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.132
MECP2 MECP2: Methyl-CpG-binding protein 2 0.052 0.060
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.152
CHUK N/A 0.052 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.0425
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.127
NCOA3 N/A 0.052 0.032
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.191
SET SET: Protein SET 0.052 0.0425
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.027
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.251
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.0425
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.070
LIMS1 N/A 0.052 0.027
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.052
MEF2A N/A 0.052 0.096
API5 N/A 0.052 0.0425
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.060
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.027
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.052
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.307
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.0425
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.0425
ATF2 N/A 0.051 0.617
ELK3 ELK3, NET, SAP2: ETS domain-containing protein Elk-3 0.051 0.051
HES1 HES1, HL, HRY: Transcription factor HES-1 0.050 0.028
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.050 0.044
CDKL5 N/A 0.049 0.031
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.049 0.034
NFIB N/A 0.049 0.055
PGR PGR, NR3C3: Progesterone receptor 0.049 0.062
PPARG CREB3L2-PPARgamma 0.049 0.062
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.111
MYF5 MYF5: Myogenic factor 5 0.049 0.035
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.097
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.049 0.136
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.251
MKI67 MKI67: Antigen KI-67 0.048 0.0425
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.025
SOX8 SOX8: Transcription factor SOX-8 0.047 0.075
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.148
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.063
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.032
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.046
SP3 SP3: Transcription factor Sp3 0.046 0.071
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.046 0.029
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.029
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.063
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.046
SSB SSB: Lupus La protein 0.046 0.063
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.029
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.071
BRPF1 BRPF1, BR140: Peregrin 0.046 0.225
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.040
MTF1 MTF1: Metal regulatory transcription factor 1 0.046 0.087
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.046
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.046 0.029
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.046 0.372
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.046
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.038
XPO1 XPO1, CRM1: Exportin-1 0.046 0.032
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.046
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.029
PCAF PCAF: Histone acetyltransferase PCAF 0.046 0.372
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 0.029
SEC31L1 N/A 0.046 0.038
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.046 0.054
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.191
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.029
COPE COPE: Coatomer subunit epsilon 0.046 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.063
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.038
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.063
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.078
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.046 0.038
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.063
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.046 0.029
SAPS3 N/A 0.046 0.038
SRF SRF: Serum response factor 0.046 0.139
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.029
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.038
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.032
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.046 0.038
WDR44 WDR44: WD repeat-containing protein 44 0.046 0.029
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 0.046
MYO3A MYO3A: Myosin IIIA 0.044 0.028
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.043
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.031
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.0308
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.099
HAND1 HAND1, EHAND: Heart- and neural crest derivatives-expressed protein 1 0.044 0.0308
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.044 0.056
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.043 0.225
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.043 0.225
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.043 0.069
SOX4 SOX4: Transcription factor SOX-4 0.043 0.086
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.052
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.027
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.032
SH3BP3 0.0425 0.048
SMARCC2 N/A 0.0425 0.032
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.0425
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.127
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.096
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.026
TCOF1 N/A 0.0425 0.032
NUP214 N/A 0.0425 0.032
SREBF2 N/A 0.0425 0.032
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.027
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.0425
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.040
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.038 0.038
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.046
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.038 0.038
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.046
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.038 0.029
MYH9 MYH9: Myosin-9 0.038 0.029
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.038 0.0425
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.038 0.029
PHF10 N/A 0.038 0.188
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.038 0.038
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.038 0.029
COPB2 COPB2: Coatomer subunit beta' 0.038 0.046
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.038 0.029
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.038 0.118
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.032
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.029
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.171
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.046
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.048
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.029
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.038 0.087
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.038 0.029
RNF11 RNF11, CGI-123: RING finger protein 11 0.038 0.029
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.038
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.035
CAT CAT: Catalase 0.038 0.066
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.046
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.038 0.111
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.038 0.038
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.029
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.046
NOL1 N/A 0.038 0.029
MDN1 MDN1, KIAA0301: Midasin 0.038 0.029
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.038 0.078
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.038 0.029
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.038
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.029
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.032
SATB1 SATB1: DNA-binding protein SATB1 0.038 0.046
NFE2 NFE2: Transcription factor NF-E2 45 kDa subunit 0.036 0.596
GABPA GABPA, E4TF1A: GA-binding protein alpha chain 0.036 0.028
FOSB FOSB, G0S3: Protein fosB 0.036 0.060
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.109
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.035 0.056
KRT20 KRT20: Keratin, type I cytoskeletal 20 0.034 0.026
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.026
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.191
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.032
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.032 0.060
UBAP2 N/A 0.032 0.052
AFF1 N/A 0.032 0.0425
ZFX ZFX: Zinc finger X-chromosomal protein 0.032 0.048
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.191
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.251
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.191
COIL COIL, CLN80: Coilin 0.032 0.032
HIVEP1 N/A 0.032 0.048
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.032
CUL2 CUL2: Cullin-2 0.032 0.076
SOX11 SOX11: Transcription factor SOX-11 0.0308 0.049
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.038
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.029 0.029
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.046
POLR2A POLR2A: Uncharacterized protein POLR2A 0.029 0.029
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.029
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.033
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.029 0.038
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.029
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.127
SP1 SP1, TSFP1: Transcription factor Sp1 0.029 0.071
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.225
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.046
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.029 0.043
UNG N/A 0.029 0.052
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.029 0.032
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 0.038
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.029 0.171
PCNA PCNA: Proliferating cell nuclear antigen 0.029 0.046
SYMPK SYMPK, SPK: Symplekin 0.029 0.038
LIG1 LIG1: DNA ligase 1 0.029 0.038
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.029 0.136
RUNX1 N/A 0.029 0.038
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.029
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.063
FZR1 N/A 0.029 0.038
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.029 0.114
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.029 0.038
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.029 0.056
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.029 0.038
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.029
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.029
KIAA0690 N/A 0.029 0.046
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.029 0.029
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
IRF7 N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
C20orf18 N/A 0.028 0.083
DSP DSP: Desmoplakin 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.052
CABLES1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.083
SNRPB N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
ZNF265 N/A 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.052
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.165
HDAC8 N/A 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.165
UHRF1 0.028 0.083
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.052
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
PHLDB2 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.052
PPEF1 N/A 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
KIF1B N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CORO6 N/A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.165
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.052
FOXL2 FOXL2: Forkhead box protein L2 0.028 0.098
RFX1 RFX1: MHC class II regulatory factor RFX1 0.028 0.097
MAFK MAFK: Transcription factor MafK 0.028 0.028
CREM hCREM-1: HCREM 1alpha protein 0.027 0.265
CREM CREM, RP11-324I22.1-005: cAMP responsive element modulator 0.027 0.265
SPIC SPIC: Transcription factor Spi-C 0.027 0.027
HSFY1 HSFY1, HSF2L, HSFY: Heat shock transcription factor, Y-linked 0.027 0.027
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.032
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.026
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.032
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.0425
EMD EMD, EDMD, STA: Emerin 0.026 0.032
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.152
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.0425
KIF23 N/A 0.026 0.052
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.032
ESPL1 N/A 0.026 0.032
PLA2G4A PLA2G4A, CPLA2, PLA2G4: Cytosolic phospholipase A2 0.0253 0.033
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.148
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.047
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.047
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.075
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.047
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
TCEA1 N/A 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
HTATIP N/A 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.047
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
SEC13L1 N/A 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
C20orf77 N/A 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.075
BRD4 N/A 0.025 0.148
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.148
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.047
GRK6 N/A 0.025 0.025
NUP98 N/A 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RNF20 0.025 0.025
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.047
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
SON 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
ATXN2L N/A 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.148
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
FLJ23436 N/A 0.025 0.028
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
NIPBL N/A 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
CAMK2A N/A 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
NES N/A 0.025 0.028
KCTD1 0.025 0.025
HDAC7A N/A 0.025 0.028
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.075
DIDO1 N/A 0.025 0.075
CAMKK1 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.083
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.047
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.047
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.047
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
0.299
Total Score 32.80