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Evidence of Interaction Between MAPK1 and UBE4A

The interaction score between MAPK1 and UBE4A is 9.32.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and UBE4A = 0.67

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology
OrganismMAPK1 OrthologueUBE4A OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly P40417 1 Q9U4F8 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains No domains were used in calculating likelihood of interaction 0.028
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: UBE4A

PTMResidueReference
Proteolytic Cleavage 127 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: UBE4A

No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between MAPK1 and UBE4A that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andUBE4A. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and UBE4A has 695 interactors of which there are 639 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for UBE4A-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.029
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.027
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.028
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.066
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.032
CDK2 CDK2: Cell division protein kinase 2 6.80 0.038
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.066
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.078
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.078
PLEK PLEK, P47: Pleckstrin 0.515 0.0446
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.052
CRKL CRKL: Crk-like protein 0.461 0.063
JAK1 0.461 0.078
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.078
MSN MSN: Moesin 0.461 0.078
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.129
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.078
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.036
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.070
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.036
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.074
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.0446
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.276
STK10 STK10: Uncharacterized protein STK10 0.385 0.078
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.087
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.078
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.063
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.0446
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.129
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.070
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.078
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.078
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.063
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.078
JUND JUND: Transcription factor jun-D 0.372 0.040
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.040
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.129
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.046
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.052
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.046
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.129
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.052
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.070
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.0425
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.036
DOK1 DOK1: Docking protein 1 0.275 0.063
JUNB JUNB: Transcription factor jun-B 0.275 0.032
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.063
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.040
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.046
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.063
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.046
HCK N/A 0.275 0.0425
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.032
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.063
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.063
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.038
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.063
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.087
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.052
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.036
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.027
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.0425
WASPIP N/A 0.233 0.087
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.129
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.066
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.070
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.129
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.129
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.129
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.063
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.078
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.129
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.066
SH3BP5 N/A 0.225 0.032
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.063
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.027
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.063
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.063
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.052
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 0.027
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.040
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.070
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.144
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.0446
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.0554
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.052
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.0425
CXorf9 N/A 0.188 0.063
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.048
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.276
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.087
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.066
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.078
RPS6KB1 N/A 0.188 0.129
FNBP1 N/A 0.188 0.129
GMIP GMIP: GEM-interacting protein 0.188 0.070
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.129
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.063
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.036
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.046
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.046
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.038
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.038
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.028
PSCD2 N/A 0.165 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.028
NF2 NF2, SCH: Merlin 0.165 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.028
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.028
ARFGAP1 N/A 0.155 0.0446
HD HD, IT15: Huntingtin 0.155 0.087
H1FX H1FX: Histone H1x 0.155 0.036
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.052
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.070
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.026
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.032
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.032
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.028
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.025
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.025
ELMO1 N/A 0.148 0.025
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.025
ARHGEF7 N/A 0.148 0.025
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.028
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.025
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.078
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.078
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.129
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.066
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.032
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.063
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.078
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.139 0.036
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.063
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.038
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.038
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.046
ATM ATM: Serine-protein kinase ATM 0.139 0.078
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.129
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.078
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.063
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.078
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.040
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.078
RDX RDX: Radixin 0.136 0.029
VIL2 N/A 0.136 0.038
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.029
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.087
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.078
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.129 0.066
RB1 RB1: Retinoblastoma-associated protein 0.127 0.027
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.032
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.070
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.052
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.0425
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.052
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.070
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.124 0.036
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.0446
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.026
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.026
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.026
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.063
PPP1R8 N/A 0.118 0.066
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.040
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.063
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.046
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.038
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.032
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.040
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.063
CDK5 CDK5: Cell division protein kinase 5 0.114 0.029
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.046
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.046
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.0425
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.078
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.078
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.038
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.032
PTMA N/A 0.0971 0.0446
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.036
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.0446
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.026
NFATC1 N/A 0.096 0.027
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.052
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.0425
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.026
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.052
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.026
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.0425
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.0425
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.036
CD44 N/A 0.091 0.0446
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.052
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.144
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.074
IFI16 N/A 0.087 0.0446
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.032
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.027
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.038
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.029
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.046
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.029
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.029
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.038
CTPS CTPS: CTP synthase 1 0.086 0.046
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.029
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.032
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.086 0.029
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.063
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.046
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.028
MAPKAPK5 N/A 0.083 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.028
MAPK15 N/A 0.083 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.0818 0.032
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.0446
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.276
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.141
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.078 0.040
LCP1 LCP1, PLS2: Plastin-2 0.078 0.078
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.087
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.129
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.078 0.037
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.078 0.066
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.078 0.141
HNRPK N/A 0.078 0.276
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.129
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.276
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.129
KLHDC4 N/A 0.078 0.078
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.129
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.078 0.040
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.078
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.066
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.032
PRKAA1 N/A 0.077 0.0425
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.026
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.070
FADD FADD, MORT1: Protein FADD 0.075 0.027
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.025
GIT2 N/A 0.075 0.025
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.028
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.028
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.028
TSC2 TSC2, TSC4: Tuberin 0.075 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.028
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.028
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.025
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.028
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.028
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.025
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.032
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.157
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.074
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.074
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.074
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.052
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.074
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.307
GTF3C1 N/A 0.070 0.036
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.036
KIAA0853 N/A 0.070 0.0446
ABCF1 N/A 0.070 0.087
CASP8 N/A 0.070 0.087
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.074
TOP2B N/A 0.070 0.074
MARK2 N/A 0.070 0.087
RGS14 N/A 0.070 0.036
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.0446
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.087
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.029
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.029
CDK4 CDK4: Cell division protein kinase 4 0.069 0.038
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.038
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.029
GSK3B N/A 0.063 0.063
CUL4B N/A 0.063 0.040
COPA COPA: Coatomer subunit alpha 0.063 0.078
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.078
PTPN11 N/A 0.063 0.078
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.040
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.129
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.066
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.129
NUP153 N/A 0.063 0.040
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.087
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.032
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.078
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.063
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.078
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.078
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.066
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.078
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.066
CUL5 CUL5, VACM1: Cullin-5 0.063 0.066
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 0.040
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.066
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.040
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.066
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.129
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.040
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.129
EXOC2 N/A 0.063 0.063
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.040
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.066
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.066
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.066
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.066
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.040
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.066
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.066
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.046
EP300 N/A 0.063 0.066
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.066
PPARBP N/A 0.063 0.129
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.066
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.078
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.066
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.129
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.063 0.040
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.026
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.026
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.026
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.0446
DNM2 N/A 0.052 0.070
MECP2 MECP2: Methyl-CpG-binding protein 2 0.052 0.027
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.036
CHUK N/A 0.052 0.087
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.052
FUBP1 N/A 0.052 0.025
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.052
NCOA3 N/A 0.052 0.036
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.027
SET SET: Protein SET 0.052 0.036
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.087
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.087
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.074
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.087
MEF2A N/A 0.052 0.036
API5 N/A 0.052 0.087
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.070
AHNAK AHNAK: AHNAK protein 0.052 0.0425
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.0446
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.027
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.036
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.052
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.052
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.026
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.026
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.025
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.040
EVL N/A 0.046 0.063
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.078
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.078
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.040
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.063
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.032
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.032
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.040
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.063
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.078
SSB SSB: Lupus La protein 0.046 0.040
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.040
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.040
BRPF1 BRPF1, BR140: Peregrin 0.046 0.063
MTF1 MTF1: Metal regulatory transcription factor 1 0.046 0.036
DLG1 N/A 0.046 0.046
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.052
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.040
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.046 0.032
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.070
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.046 0.038
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.046
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.032
XPO1 XPO1, CRM1: Exportin-1 0.046 0.129
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.063
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.066
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.129
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 0.032
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.063
LPXN LPXN, LDLP: Leupaxin 0.046 0.087
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.0446
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.040
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.063
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.040
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.078
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.040
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.046 0.040
SAPS3 N/A 0.046 0.078
SRF SRF: Serum response factor 0.046 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.063
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.040
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.078
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.078
WDR44 WDR44: WD repeat-containing protein 44 0.046 0.040
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 0.066
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.027
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.0446 0.074
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.032
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.029
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.036
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.052
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.0425
DAPP1 N/A 0.0425 0.052
MPG N/A 0.0425 0.052
SMARCC2 N/A 0.0425 0.036
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.027
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.032
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.036
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.0446
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.0446
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.052
PDE4A N/A 0.0425 0.026
TCOF1 N/A 0.0425 0.036
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.0425
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.027
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.0425
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.032
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.040 0.032
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.040
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.038 0.032
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.032
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.032
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.038 0.032
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.038 0.027
PHF10 N/A 0.038 0.032
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.038
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.032
APC N/A 0.038 0.029
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.032
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.078
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.036
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.040
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.087
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.038 0.040
WBSCR20A N/A 0.038 0.040
CFL1 CFL1, CFL: Cofilin-1 0.038 0.046
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.036
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.078
CAT CAT: Catalase 0.038 0.038
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.040
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.038 0.032
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.029
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.046
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.046
MDN1 MDN1, KIAA0301: Midasin 0.038 0.078
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.063
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.046
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.038 0.032
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.063
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.063
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.063
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.063
SATB1 SATB1: DNA-binding protein SATB1 0.038 0.036
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.0446
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.036
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.0446
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.036
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.027
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.0446
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.036 0.0446
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.0446
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.0446
GLG1 GLG1: Golgi apparatus protein 1 0.036 0.0446
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.036 0.0446
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.0425
CP110 N/A 0.032 0.0425
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.032
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.036
ZYX ZYX: Zyxin 0.032 0.032
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.027
MAP2K5 N/A 0.032 0.032
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.036
UBAP2 N/A 0.032 0.0425
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.036
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.027
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.032
COIL COIL, CLN80: Coilin 0.032 0.027
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.027
MAN2A1 MAN2A1, MANA2: Alpha-mannosidase 2 0.032 0.066
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.032 0.040
NCSTN NCSTN, KIAA0253, UNQ1874/PRO4317: Nicastrin precursor 0.032 0.032
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.032 0.066
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.0446
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.063
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.046
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.029
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.063
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.027
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.032
UNG N/A 0.029 0.036
THOP1 THOP1: Thimet oligopeptidase 0.029 0.0425
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 0.032
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.032
SYMPK SYMPK, SPK: Symplekin 0.029 0.038
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.046
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.029 0.029
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.038
IMPAD1 N/A 0.029 0.038
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.038
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.038
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.038
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.038
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.038
AHCYL1 AHCYL1, DCAL, XPVKONA: Putative adenosylhomocysteinase 2 0.029 0.038
PMM1 PMM1, PMMH22: Phosphomannomutase 1 0.029 0.029
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.038
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.027
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.046
KIAA0690 N/A 0.029 0.029
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.029 0.029
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.029 0.029
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.028
AXIN1 0.028 0.028
MATK 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.027
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.027 0.027
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.036
CD69 CD69: Early activation antigen CD69 0.027 0.036
ITGAE ITGAE: Integrin alpha-E precursor 0.027 0.036
TRRAP N/A 0.026 0.0425
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.032
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.026
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.0425
IREB2 IREB2: Iron-responsive element-binding protein 2 0.026 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.032
ESPL1 N/A 0.026 0.032
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.028
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
MYO18A 0.025 0.025
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.028
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.028
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
PRKCB1 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.025
RAC1 N/A 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.028
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.025
CAMKK1 N/A 0.025 0.028
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.025
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
0.299
Total Score 9.32