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Evidence of Interaction Between MAPK1 and ZNF267

The interaction score between MAPK1 and ZNF267 is 5.08.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and ZNF267 = 0.34

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 3.80E-3
Orthology N/A N/A
Domains Domains present in MAPK1 and ZNF267:
Domains in MAPK1Domains in ZNF267
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001909 KRAB box
IPR007087 Zn-finger, C2H2 type
IPR007086 Zn-finger, C2H2 subtype

The Chi square scores for co-occurrence of domains that are present in MAPK1 and ZNF267 are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR007087 Zn-finger, C2H2 type 47.9924
IPR011009 Protein kinase-like IPR007087 Zn-finger, C2H2 type 29.7037
IPR008271 Serine/threonine protein kinase, active site IPR007087 Zn-finger, C2H2 type 19.0493
IPR002290 Serine/threonine protein kinase IPR007087 Zn-finger, C2H2 type 12.068

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in ZNF267
  • Green Domain is present in both MAPK1 and ZNF267

 0.028
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: ZNF267

PTMResidueReference
Phosphotyrosine 520 HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: ZNF267

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between MAPK1 and ZNF267 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andZNF267. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and ZNF267 has 1162 interactors of which there are 736 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for ZNF267-Interactor (?)
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.026
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.028
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.028
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.028
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.070
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.070
CDK2 CDK2: Cell division protein kinase 2 6.80 0.032
HSPD1 6.11 0.027
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.052
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.144
PLEK PLEK, P47: Pleckstrin 0.515 0.260
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.036
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.0425
CRKL CRKL: Crk-like protein 0.461 0.027
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.0425
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.070
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.027
MSN MSN: Moesin 0.461 0.036
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.036
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.0425
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.260
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.155
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.0425
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.052
STK10 STK10: Uncharacterized protein STK10 0.385 0.052
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.027
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.101
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.155
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.027
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.127
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.027
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.027
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.036
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.027
JUND JUND: Transcription factor jun-D 0.372 0.096
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.096
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.036
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.027
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.384
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.0425
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.070
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.070
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.0446
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.027
DOK1 DOK1: Docking protein 1 0.275 0.052
JUNB JUNB: Transcription factor jun-B 0.275 0.127
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.027
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.0971
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.032
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.052
HCK N/A 0.275 0.027
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.096
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 0.048
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.036
GAB2 N/A 0.251 0.032
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.052
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.307
DUSP12 DUSP12: Dual specificity protein phosphatase 12 0.237 0.027
WASPIP N/A 0.233 0.0446
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.036
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.052
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.052
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.036
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.070
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.0425
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.052
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.070
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.036
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.260
CCNH CCNH: Cyclin-H 0.225 0.127
JUN JUN: Transcription factor AP-1 0.225 0.062
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.036
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.061
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.048
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.052
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 0.127
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.032
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.030
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.210
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.0425
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.052
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.0425
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.027
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.026
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.027
GMIP GMIP: GEM-interacting protein 0.188 0.036
CXorf9 N/A 0.188 0.070
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.155
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.030
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.052
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.0425
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.052
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.052
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.052
RPS6KB1 N/A 0.188 0.052
FNBP1 N/A 0.188 0.087
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.152
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.127
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.028
NF2 NF2, SCH: Merlin 0.165 0.028
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.070
HD HD, IT15: Huntingtin 0.155 0.091
ARFGAP1 N/A 0.155 0.0425
H1FX H1FX: Histone H1x 0.155 0.077
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.032
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.096
ETS2 ETS2: Protein C-ets-2 0.152 0.077
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.083
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.028
CREB1 CREB1: cAMP response element-binding protein 0.148 0.083
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.028
CCNT2 CCNT2: Cyclin-T2 0.148 0.083
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.028
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.028
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.083
ELMO1 N/A 0.148 0.028
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.028
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.027
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.027
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.036
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.0425
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.052
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.0425
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.0425
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.139 0.0425
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.032
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.052
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.026
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.026
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.0425
ATM ATM: Serine-protein kinase ATM 0.139 0.032
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.070
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.032
CD2AP CD2AP: CD2-associated protein 0.139 0.036
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.027
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.096
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.127
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.152
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.152
CCNB1 Cyclin B1 0.136 0.096
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.136 0.048
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.136 0.096
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.027
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.0425
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.129 0.032
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.036
RB1 RB1: Retinoblastoma-associated protein 0.127 0.155
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.0425
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.087
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.070
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.0425
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.070
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.127 0.077
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.032
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.037
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.027
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.210
PPP1R8 N/A 0.118 0.052
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.155
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.114 0.060
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.032
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.114 0.0425
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.0425
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.032
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.0425
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.096
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.032
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.0425
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.026
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.032
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.027
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.062
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.026
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.055
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.049
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.034
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.062
SP100 N/A 0.0971 0.030
PTMA N/A 0.0971 0.052
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.155
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.430
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.0425
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.036
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.026
NFATC1 N/A 0.096 0.152
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.075
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.0425
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.032
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.070
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.032
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.049
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.032
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.052
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.307
IFI16 N/A 0.087 0.070
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.155
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.052
AHR AHR: Aryl hydrocarbon receptor precursor 0.086 0.026
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.032
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.032
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.0425
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.052
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.032
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.032
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.077
RELA RELA, NFKB3: Transcription factor p65 0.086 0.127
MTA1 MTA1: Metastasis-associated protein MTA1 0.086 0.210
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.096
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.052
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.027
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.155
MAPKAPK5 N/A 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.028
MAPK15 N/A 0.083 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.028
HES6 HES6: Transcription cofactor HES-6 0.083 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.028
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.155
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.027
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.070
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.052
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.0446
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.210
LCP1 LCP1, PLS2: Plastin-2 0.078 0.0446
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.078 0.052
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.052
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.070
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.078 0.251
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.078 0.127
HNRPK N/A 0.078 0.036
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.052
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.052
KLHDC4 N/A 0.078 0.0425
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.078 0.051
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.078 0.052
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.032
MYB MYB: Myb proto-oncogene protein 0.077 0.077
PRKAA1 N/A 0.077 0.032
STK16 N/A 0.077 0.0425
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.037
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.028
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.028
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.083
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.028
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.028
MAX MAX: Protein max 0.075 0.028
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.028
GIT2 N/A 0.075 0.028
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.028
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.028
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.083
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.028
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.028
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.028
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.028
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.028
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.028
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.083
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.028
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.083
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.028
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.028
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.028
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.028
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.032
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.070
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.027
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.052
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.026
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.127
RGS14 N/A 0.070 0.052
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.0425
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.070
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.032
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.307
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.251
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.052
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.155
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.070
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.0425
GTF3C1 N/A 0.070 0.032
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.032
KIAA0853 N/A 0.070 0.0425
ABCF1 N/A 0.070 0.070
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.052
TOP2B N/A 0.070 0.052
WDR1 N/A 0.070 0.052
MARK2 N/A 0.070 0.0425
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.0425
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.077
VDR VDR, NR1I1: Vitamin D3 receptor 0.069 0.077
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.0425
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.026
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.026
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.032
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.032
CDK4 CDK4: Cell division protein kinase 4 0.069 0.0425
TIAL1 TIAL1: Nucleolysin TIAR 0.063 0.070
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.036
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.063 0.052
CUL4B N/A 0.063 0.052
COPA COPA: Coatomer subunit alpha 0.063 0.0425
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.027
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.063 0.070
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.052
GSK3B N/A 0.063 0.0425
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.052
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.127
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.166
NUP153 N/A 0.063 0.070
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.052
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.0425
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.0425
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.052
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.036
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.052
CUL5 CUL5, VACM1: Cullin-5 0.063 0.052
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 0.052
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.052
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.0425
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.210
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.036
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.036
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.070
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.052
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.027
EXOC2 N/A 0.063 0.057
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.307
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.052
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.052
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.063 0.210
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.063 0.103
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.307
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.416
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 1.98
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.155
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.155
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.070
EP300 N/A 0.063 0.0425
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.210
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.307
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.027
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.070
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.063 0.070
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.062
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.034
GTF2F2 N/A 0.060 0.096
VIM VIM: Vimentin 0.060 0.026
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.077
WEE1 WEE1: Wee1-like protein kinase 0.056 0.032
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.056 0.096
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.032
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.056 0.026
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.056 0.096
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.026
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.056 0.049
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.055 0.026
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.048
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.055 0.055
TP73 TP73, P73: Tumor protein p73 0.055 0.062
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.0425
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.055
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.032
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.033
RAB4A N/A 0.052 0.028
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.032
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.027
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.027
DNM2 N/A 0.052 0.027
MECP2 MECP2: Methyl-CpG-binding protein 2 0.052 0.039
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.127
CHUK N/A 0.052 0.052
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.026
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.103
FUBP1 N/A 0.052 0.027
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.155
NCOA3 N/A 0.052 0.052
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.096
SET SET: Protein SET 0.052 0.0425
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.085
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.0425
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.070
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.052 0.0425
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.070
MEF2A N/A 0.052 0.032
API5 N/A 0.052 0.0425
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.140
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.210
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.062
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.052
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.050 0.055
NFIB N/A 0.049 0.049
PGR PGR, NR3C3: Progesterone receptor 0.049 0.062
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.026
ARRB2 N/A 0.049 0.0407
GTF2A1 GTF2A1, TF2A1: Transcription initiation factor IIA subunit 1 0.049 0.026
PPARG CREB3L2-PPARgamma 0.049 0.055
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.055
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.026
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.049 0.062
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.096
MKI67 MKI67: Antigen KI-67 0.048 0.032
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.037
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.0425
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.155
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.032
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.074
WDR44 WDR44: WD repeat-containing protein 44 0.046 0.032
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.046 0.070
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 0.0425
SRF SRF: Serum response factor 0.046 0.052
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.027
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.046 0.070
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.070
SP3 SP3: Transcription factor Sp3 0.046 0.140
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.046 0.026
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.027
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.416
DMXL2 DMXL2, KIAA0856: DmX-like protein 2 0.046 0.032
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.052
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.052
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.027
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.027
SSB SSB: Lupus La protein 0.046 0.052
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.046 0.070
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.210
CORO1C CORO1C, CRNN4: Coronin-1C 0.046 0.052
BRPF1 BRPF1, BR140: Peregrin 0.046 0.191
MTF1 MTF1: Metal regulatory transcription factor 1 0.046 0.191
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.052
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.046 0.152
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.046 0.152
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.027
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.032
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.070
XPO1 XPO1, CRM1: Exportin-1 0.046 0.027
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.036
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.127
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.0425
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.0425
PCAF PCAF: Histone acetyltransferase PCAF 0.046 0.0416
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 0.096
LPXN LPXN, LDLP: Leupaxin 0.046 0.036
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.046 0.064
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.307
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.026
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.0425
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.032
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.0425
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.027
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.036
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.052
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.046 0.096
SAPS3 N/A 0.046 0.032
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.070
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.123
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.044 0.055
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.043 0.077
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.043 0.096
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.043 0.077
SOX4 SOX4: Transcription factor SOX-4 0.043 0.077
TCOF1 N/A 0.0425 0.052
NUP214 N/A 0.0425 0.0425
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.052
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.032
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.096
GNB2L1 Lung cancer oncogene 7 0.0425 0.0425
SH3BP3 0.0425 0.085
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.0425
SMARCC2 N/A 0.0425 0.0425
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.0425
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.0425
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.0425
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.027
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.038 0.0425
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.026
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.074
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.027
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.038 0.0425
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.038 0.052
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.307
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.038 0.026
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.052
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.038 0.032
MYH9 MYH9: Myosin-9 0.038 0.052
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.038 0.032
PHF10 N/A 0.038 0.191
RP2 RP2: Protein XRP2 0.038 0.036
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.038 0.052
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.038 0.096
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.038 0.155
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.038 0.052
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.038 0.191
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.038 0.0425
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.307
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.032
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.052
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.251
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.0425
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.0425
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.036
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.038 0.127
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.038 0.032
RNF11 RNF11, CGI-123: RING finger protein 11 0.038 0.055
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.0425
WBSCR20A N/A 0.038 0.052
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.0446
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.416
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.070
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.052
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.027
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.038 0.052
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.052
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.032
MDN1 MDN1, KIAA0301: Midasin 0.038 0.0425
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.038 0.251
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.038 0.026
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.038 0.052
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.0425
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.038 0.0425
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.062
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.035 0.055
HIVEP1 N/A 0.032 0.251
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.026
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.032
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.127
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.052
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.032 0.152
UBAP2 N/A 0.032 0.0425
AFF1 N/A 0.032 0.032
ZFX ZFX: Zinc finger X-chromosomal protein 0.032 0.251
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.307
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.251
COIL COIL, CLN80: Coilin 0.032 0.032
AP2M1 AP2M1, CLAPM1, KIAA0109: AP-2 complex subunit mu-1 0.032 0.025
SOX11 SOX11: Transcription factor SOX-11 0.0308 0.055
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.029 0.070
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.029 0.052
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.052
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.032
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.027
POLB POLB: DNA polymerase beta 0.029 0.0425
KIAA0690 N/A 0.029 0.026
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.029 0.0425
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.052
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.029 0.0425
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.052
POLR2A POLR2A: Uncharacterized protein POLR2A 0.029 0.032
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.0425
RBM7 0.029 0.052
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.032
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.029 0.032
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.0425
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.155
SP1 SP1, TSFP1: Transcription factor Sp1 0.029 0.123
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.096
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.0425
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.052
THOP1 THOP1: Thimet oligopeptidase 0.029 0.027
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 0.052
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.0425
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.029 0.191
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.029 0.152
UNG N/A 0.029 0.0425
SYMPK SYMPK, SPK: Symplekin 0.029 0.0425
LIG1 LIG1: DNA ligase 1 0.029 0.0425
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.027
PCNA PCNA: Proliferating cell nuclear antigen 0.029 0.0425
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.029 0.123
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.026
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.032
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.191
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.0425
FZR1 N/A 0.029 0.0425
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.029 0.032
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.029 0.060
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.027
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.029 0.051
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.165
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.083
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.109
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
WDR54 N/A 0.028 0.028
C20orf18 N/A 0.028 0.165
DSP DSP: Desmoplakin 0.028 0.028
CABLES1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.165
SNRPB N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
ZNF265 N/A 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.056
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
HDAC8 N/A 0.028 0.165
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.165
DUSP15 N/A 0.028 0.028
AXIN1 0.028 0.049
UHRF1 0.028 0.056
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.165
PHLDB2 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.083
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.165
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.083
KIF1B N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.165
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.165
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
RFX1 RFX1: MHC class II regulatory factor RFX1 0.028 0.055
FOXL2 FOXL2: Forkhead box protein L2 0.028 0.062
ESPL1 N/A 0.026 0.0425
CEP170 CEP170, FAM68A, KAB, KIAA0470: Centrosomal protein of 170 kDa 0.026 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.0425
TRRAP N/A 0.026 0.0425
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.062
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.032
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.026 0.152
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.052
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.026
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.027
EMD EMD, EDMD, STA: Emerin 0.026 0.032
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.032
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.026
KIF23 N/A 0.026 0.032
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.165
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.028
ADK ADK: Adenosine kinase 0.025 0.028
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.028
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.028
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.028
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.028
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.028
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.083
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.028
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.028
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.165
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.028
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.165
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.028
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.165
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.083
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.028
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.028
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.028
TCEA1 N/A 0.025 0.028
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 1.30
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.028
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.028
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.165
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.028
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.028
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.028
HTATIP N/A 0.025 0.028
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.028
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.028
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.165
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.028
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.028
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.028
MAPK8IP3 N/A 0.025 0.028
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.028
C20orf77 N/A 0.025 0.028
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.04
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.165
BRD4 N/A 0.025 0.165
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.028
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.028
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.083
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.028
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.028
BCOR N/A 0.025 0.028
MAP2K3 N/A 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.028
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.028
GRK6 N/A 0.025 0.028
NUP98 N/A 0.025 0.028
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.028
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.028
RNF20 0.025 0.083
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.165
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.028
SON 0.025 0.028
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.028
PRKCB1 N/A 0.025 0.028
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.028
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.028
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.028
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.165
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.028
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.083
ATXN2L N/A 0.025 0.028
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.028
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.028
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.028
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.028
FLJ23436 N/A 0.025 0.028
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.083
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.028
CAMK2A N/A 0.025 0.028
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.028
NES N/A 0.025 0.028
KCTD1 0.025 0.028
HDAC7A N/A 0.025 0.165
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.165
DIDO1 N/A 0.025 0.056
CAMKK1 N/A 0.025 0.028
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.083
0.299
Total Score 5.08