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Evidence of Interaction Between MAPK1 and SMAD2

The interaction score between MAPK1 and SMAD2 is 27.80.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and SMAD2 = 0.64

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology
OrganismMAPK1 OrthologueSMAD2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P39745 1 Q02330 0.185
fly P40417 1 O96660 0.72

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and SMAD2:
Domains in MAPK1Domains in SMAD2
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR003619 Dwarfin protein, domain A
IPR001132 Dwarfin protein
IPR013019 MAD_MH1.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and SMAD2 are listed below.

Domain 1Domain 2Chi Square
IPR011009 Protein kinase-like IPR003619 Dwarfin protein, domain A 12.3099
IPR011009 Protein kinase-like IPR013019 MAD_MH1. 12.1698
IPR011009 Protein kinase-like IPR001132 Dwarfin protein 12.1698
IPR000719 Protein kinase IPR003619 Dwarfin protein, domain A 6.02148
IPR000719 Protein kinase IPR013019 MAD_MH1. 5.86622
IPR000719 Protein kinase IPR001132 Dwarfin protein 5.86622
IPR002290 Serine/threonine protein kinase IPR003619 Dwarfin protein, domain A 2.38964
IPR002290 Serine/threonine protein kinase IPR001132 Dwarfin protein 2.3306
IPR002290 Serine/threonine protein kinase IPR013019 MAD_MH1. 2.3306
IPR008271 Serine/threonine protein kinase, active site IPR003619 Dwarfin protein, domain A 0.0575769
IPR008271 Serine/threonine protein kinase, active site IPR001132 Dwarfin protein 0.0449629
IPR008271 Serine/threonine protein kinase, active site IPR013019 MAD_MH1. 0.0449629

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in SMAD2
  • Green Domain is present in both MAPK1 and SMAD2

 0.083
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: SMAD2

PTMResidueReference
Phosphorylation 8 PubMed, HPRD
Phosphorylation 110 PubMed, HPRD
Phosphorylation 220 PubMed, HPRD
Phosphorylation 240 PubMed, HPRD
Phosphorylation 245 PubMed, HPRD
Phosphorylation 250 PubMed, HPRD
Phosphorylation 260 PubMed, HPRD
Phosphorylation 464 PubMed, HPRD
Phosphorylation 465 PubMed, HPRD
Phosphorylation 467 PubMed, HPRD
Phosphoserine 240 PubMed, HPRD
Phosphoserine 465 HPRD
Phosphoserine 467 HPRD
Phosphothreonine 8 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: SMAD2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and SMAD2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andSMAD2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and SMAD2 has 1164 interactors of which there are 926 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for SMAD2-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 33.10
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.046
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.046
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.025
DIAPH1 Diaphanous 1 20.60 0.129
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.129
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 10.50 0.038
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.078
CDK2 CDK2: Cell division protein kinase 2 6.80 0.046
HSPD1 6.11 0.032
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.129
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.032
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.066
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.129
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.032
PLEK PLEK, P47: Pleckstrin 0.515 0.144
COPS5 COPS5, CSN5, JAB1: COP9 signalosome complex subunit 5 0.475 1.40
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.063
CRKL CRKL: Crk-like protein 0.461 0.032
JAK1 0.461 0.040
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.063
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.078
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.137
MSN MSN: Moesin 0.461 0.066
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.066
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.066
ID2 ID2: DNA-binding protein inhibitor ID-2 0.430 0.087
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.036
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.430
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.430
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.210
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.129
STK10 STK10: Uncharacterized protein STK10 0.385 0.129
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.227
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.146
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.066
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.032
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.385
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.111
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.040
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.066
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.066
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.032
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.032
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.040
JUND JUND: Transcription factor jun-D 0.372 0.188
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.063
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.040
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.032
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.276
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.070
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.087
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.027
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.027
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.087
DOK1 DOK1: Docking protein 1 0.275 0.063
JUNB JUNB: Transcription factor jun-B 0.275 0.188
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.040
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.063
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.046
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.063
MAFG MAFG: Transcription factor MafG 0.275 0.114
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.139
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 0.114
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.066
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.032
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.066
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.036
GAB2 N/A 0.251 0.032
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.027
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.087
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.124
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.155
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.032
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.233
WASPIP N/A 0.233 0.066
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.066
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.129
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.078
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.141
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.276
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.078
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.078
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.129
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.066
JUN JUN: Transcription factor AP-1 0.225 0.114
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.040
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.225 0.139
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.038
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.078
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.040
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 0.139
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.118
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.188
CCNH CCNH: Cyclin-H 0.225 0.046
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.144
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.144
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.0446
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.163
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.144
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.425
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.192 0.156
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.052
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.036
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.0425
CXorf9 N/A 0.188 0.385
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.040
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.385
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.078
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.129
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.063
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.241
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.078
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.129
RPS6KB1 N/A 0.188 0.129
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.046
FNBP1 N/A 0.188 0.276
GMIP GMIP: GEM-interacting protein 0.188 0.032
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.066
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.028
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.029
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.139
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.067
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.067
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.028
BID BID: BH3-interacting domain death agonist 0.165 0.028
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.083
MAP2K5 N/A 0.165 0.049
NF2 NF2, SCH: Merlin 0.165 0.028
ARFGAP1 N/A 0.155 0.070
HD HD, IT15: Huntingtin 0.155 0.0446
H1FX H1FX: Histone H1x 0.155 0.155
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.0425
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.0446
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.052
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.087
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.127
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.026
ETS2 ETS2: Protein C-ets-2 0.152 0.096
CREB1 CREB1: cAMP response element-binding protein 0.148 0.075
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
CCNT2 CCNT2: Cyclin-T2 0.148 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.044
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.025
ELMO1 N/A 0.148 0.025
ARHGEF7 N/A 0.148 6.17
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.036
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.044
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.040
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.503
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.503
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.129
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.063
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.078
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.040
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.078
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.139 0.046
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.046
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.078
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.038
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.029
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.063
ATM ATM: Serine-protein kinase ATM 0.139 0.046
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.129
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.063
CD2AP CD2AP: CD2-associated protein 0.139 0.040
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.032
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.139
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.111
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.118
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.063
ELF4 ELF4, ELFR, MEF: ETS-related transcription factor Elf-4 0.137 0.042
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
CCNB1 Cyclin B1 0.136 0.038
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.026
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.136 0.086
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.136 0.086
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.0308
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.340
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.129
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.129 0.129
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.141
RB1 RB1: Retinoblastoma-associated protein 0.127 0.132
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.032
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.070
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.144
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.070
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.052
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.070
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.127 0.032
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.0446
ERG ERG: Transcriptional regulator ERG 0.123 0.077
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.032
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.057
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.233
PPP1R8 N/A 0.118 0.385
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.233
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.304
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.063
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.063
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.114 0.063
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.046
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.137
CDK5 CDK5: Cell division protein kinase 5 0.114 0.029
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.038
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.139
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.029
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.046
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.029
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.040
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.032
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.038
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.114 0.114
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.046
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.155
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.049
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.111 0.069
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.062
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.0263
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.031
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.056
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.035
PTMA N/A 0.0971 0.144
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.260
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.917
SP100 N/A 0.0971 0.260
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.191
NFATC1 N/A 0.096 0.052
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.027
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.070
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.027
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.026
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.052
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.087
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.026
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.0425
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.077
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.052
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.027
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.052
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.144
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.430
IFI16 N/A 0.087 0.307
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.385
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.078
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.046
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.063
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.063
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.046
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.046
CTPS CTPS: CTP synthase 1 0.086 0.032
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 66.70
RELA RELA, NFKB3: Transcription factor p65 0.086 0.046
MTA1 MTA1: Metastasis-associated protein MTA1 0.086 0.063
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.139
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.063
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.032
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.146
AHR AHR: Aryl hydrocarbon receptor precursor 0.086 0.038
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.038
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.049
MAPKAPK5 N/A 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.049
MAPK15 N/A 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.028
HES6 HES6: Transcription cofactor HES-6 0.083 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.028
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.260
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.129
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.394
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.129
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.078 0.129
LCP1 LCP1, PLS2: Plastin-2 0.078 0.394
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 15.50
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.078
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.129
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.129
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.078 0.078
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.078 0.129
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.078 0.129
HNRPK N/A 0.078 0.141
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.129
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.066
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 0.040
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.129
UBE4A N/A 0.078 0.066
KLHDC4 N/A 0.078 0.078
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.040
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.078 0.188
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.078 0.233
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.040
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.276
MYB MYB: Myb proto-oncogene protein 0.077 0.077
PRKAA1 N/A 0.077 0.032
STK16 N/A 0.077 0.0425
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.057
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.0425
MAX MAX: Protein max 0.075 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.025
GIT2 N/A 0.075 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.075
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.047
CNN2 CNN2: Calponin-2 0.075 0.049
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.075
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.047
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.025
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.047
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.025
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 35.90
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.025
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.028
FLI1 FLI1: Friend leukemia integration 1 transcription factor 0.074 0.038
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.228
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.086
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.078
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.029
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.040
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.304
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.078
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.038
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.188
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.144
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.430
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.144
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.144
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.036
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.087
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.087
GTF3C1 N/A 0.070 0.070
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.070
KIAA0853 N/A 0.070 0.087
ABCF1 N/A 0.070 0.144
CASP8 N/A 0.070 0.036
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.144
TOP2B N/A 0.070 0.087
IFI35 N/A 0.070 0.074
WDR1 N/A 0.070 0.430
MARK2 N/A 0.070 0.070
RGS14 N/A 0.070 0.070
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.087
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.144
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.087
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.086
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.056
VDR VDR, NR1I1: Vitamin D3 receptor 0.069 0.086
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.071
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.029
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.114
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.029
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.029
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.029
CDK4 CDK4: Cell division protein kinase 4 0.069 0.063
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.032
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.046
GSK3B N/A 0.063 0.078
CUL4B N/A 0.063 0.078
COPA COPA: Coatomer subunit alpha 0.063 0.233
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.063 0.129
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.040
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.040
PTPN11 N/A 0.063 0.040
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.063 0.129
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.188
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.129
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.078
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.137
NUP153 N/A 0.063 0.129
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.066
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.063 0.078
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.063 0.032
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.040
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.385
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.066
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.040
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.054
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.032
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.275
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.129
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.063 0.078
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.040
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.129
CUL5 CUL5, VACM1: Cullin-5 0.063 0.078
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 0.129
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.063 0.033
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.129
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.063 0.078
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.129
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.066
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.066
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.129
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.032
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.063 0.129
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.040
EXOC2 N/A 0.063 0.032
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.385
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.129
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.129
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.063 0.129
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.063 0.241
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.385
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.276
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 0.233
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.063 0.233
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.129
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.276
EP300 N/A 0.063 0.078
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.385
PPARBP N/A 0.063 0.066
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.822
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.032
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.129
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.063 0.129
FRG1 FRG1: Protein FRG1 0.063 0.040
TIAL1 TIAL1: Nucleolysin TIAR 0.063 0.129
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.066
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.063 0.233
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.026
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.026
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.026
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.062
GRLF1 N/A 0.062 0.123
GTF2F2 N/A 0.060 0.127
VIM VIM: Vimentin 0.060 0.0425
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.251
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.056 0.086
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.029
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.051
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.056 0.044
WEE1 WEE1: Wee1-like protein kinase 0.056 0.038
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.055 0.032
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.062
TP73 TP73, P73: Tumor protein p73 0.055 0.062
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.046
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.136
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.038
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.083
RAB4A N/A 0.052 0.165
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.165
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.430
DNM2 N/A 0.052 0.036
MECP2 MECP2: Methyl-CpG-binding protein 2 0.052 0.0425
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.210
CHUK N/A 0.052 0.087
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.052
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.144
FUBP1 N/A 0.052 0.074
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.027
MVP MVP, LRP: Major vault protein 0.052 0.036
NCOA3 N/A 0.052 0.144
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.155
SET SET: Protein SET 0.052 0.087
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.036
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.132
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.052 0.087
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.070
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.087
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.144
LIMS1 N/A 0.052 0.036
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.144
MEF2A N/A 0.052 0.155
API5 N/A 0.052 0.087
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.430
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.036
AHNAK AHNAK: AHNAK protein 0.052 0.027
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.144
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.127
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.087
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.052
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.0446
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.101
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.0446
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.071
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.026
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.049 0.026
NFIB N/A 0.049 0.031
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.056
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.069
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.049 0.056
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.096
MKI67 MKI67: Antigen KI-67 0.048 0.127
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.025
SOX8 SOX8: Transcription factor SOX-8 0.047 0.075
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.098
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.075
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.129
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.040
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.046 0.276
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.304
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.129
SP3 SP3: Transcription factor Sp3 0.046 0.233
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.046 0.038
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.066
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.032
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.078
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.078
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.129
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.040
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.066
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.032
SSB SSB: Lupus La protein 0.046 0.078
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.046 0.129
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.078
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.129
CORO1C CORO1C, CRNN4: Coronin-1C 0.046 0.233
BRPF1 BRPF1, BR140: Peregrin 0.046 0.114
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.032
MTF1 MTF1: Metal regulatory transcription factor 1 0.046 90.40
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.032
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.032
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.063
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.046 0.029
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.046 0.087
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.066
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.032
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.046
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.066
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.046 0.078
XPO1 XPO1, CRM1: Exportin-1 0.046 0.066
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.032
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.078
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.078
PCAF PCAF: Histone acetyltransferase PCAF 0.046 0.086
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 0.046
SEC31L1 N/A 0.046 0.233
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.040
LPXN LPXN, LDLP: Leupaxin 0.046 0.066
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.046 0.188
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.146
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.046
COPE COPE: Coatomer subunit epsilon 0.046 0.063
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.129
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.063
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.040
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.046
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.066
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.078
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.066
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.046 0.063
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.066
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.129
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.046 0.063
SAPS3 N/A 0.046 0.063
SRF SRF: Serum response factor 0.046 0.233
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.063
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.078
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.040
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.139
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.040
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.046 0.188
WDR44 WDR44: WD repeat-containing protein 44 0.046 0.063
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.046 0.078
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 0.063
CNN3 CNN3: Calponin-3 0.044 0.037
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.027
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.056
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.044 0.049
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 29.60
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.043 0.086
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.043 0.086
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.043 0.086
SOX4 SOX4: Transcription factor SOX-4 0.043 0.086
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.052
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.036
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.155
DAPP1 N/A 0.0425 0.036
MPG N/A 0.0425 0.036
GNB2L1 Lung cancer oncogene 7 0.0425 0.260
SH3BP3 0.0425 0.127
SMARCC2 N/A 0.0425 0.052
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.052
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.070
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.260
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.052
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.070
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.027
TCOF1 N/A 0.0425 0.087
NUP214 N/A 0.0425 0.096
SREBF2 N/A 0.0425 0.070
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.070
RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 0.039 0.435
RAB8A RAB8A: RAB8A protein 0.039 0.257
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.039 0.100
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.038 0.078
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.063
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.038 0.029
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.078
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.040
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.038 0.046
MYH9 MYH9: Myosin-9 0.038 0.063
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.038 0.046
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.038 0.046
PHF10 N/A 0.038 0.063
RP2 RP2: Protein XRP2 0.038 0.032
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.038 0.063
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.038 0.029
COPB2 COPB2: Coatomer subunit beta' 0.038 0.188
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.038 0.063
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.040
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.040
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.038 0.063
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.038 0.139
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.063
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 0.032
CREBBP CREBBP, CBP: CREB-binding protein 0.038 90.40
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.038
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.129
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.040
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.188
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.038 0.063
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.040
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.040
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.038 0.188
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.038 0.086
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.233
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.063
WBSCR20A N/A 0.038 0.078
DYNC1I2 N/A 0.038 0.086
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.188
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.129
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.040
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.040
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.078
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.040
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.038 18.30
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.038 0.078
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.046
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.046
NOL1 N/A 0.038 0.078
MDN1 MDN1, KIAA0301: Midasin 0.038 0.063
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.245
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.038 0.038
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.038 0.063
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.038 0.046
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.038 0.188
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.040
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.032
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.066
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.038 0.233
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.038
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.040
SATB1 SATB1: DNA-binding protein SATB1 0.038 0.114
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.040
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.038 0.063
RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 0.0354 0.111
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.225
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.035 0.056
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 27.30
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.052
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.155
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.070
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.032 0.096
UBAP2 N/A 0.032 0.052
AFF1 N/A 0.032 0.070
XRCC4 N/A 0.032 0.032
ZFX ZFX: Zinc finger X-chromosomal protein 0.032 0.155
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.027
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.260
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.132
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.0971
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.027
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.032 0.027
COIL COIL, CLN80: Coilin 0.032 0.0425
HIVEP1 N/A 0.032 0.127
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.027
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.0425
CUL2 CUL2: Cullin-2 0.032 0.075
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.073
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.072
SOX11 SOX11: Transcription factor SOX-11 0.0308 0.049
CCNF CCNF: G2/mitotic-specific cyclin-F 0.0308 0.041
XAB1 XAB1, MBDIN, HUSSY-23: XPA-binding protein 1 0.030 0.055
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.063
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.029 0.046
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.063
POLR2A POLR2A: Uncharacterized protein POLR2A 0.029 0.038
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.063
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.067
RBM7 0.029 0.063
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.029 0.114
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.051
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.029 0.046
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.063
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.063
SP1 SP1, TSFP1: Transcription factor Sp1 0.029 0.069
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.114
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.188
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.029 0.114
UNG N/A 0.029 0.063
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.078
THOP1 THOP1: Thimet oligopeptidase 0.029 0.032
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.029
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 0.078
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.063
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.029 0.029
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.038
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.029 0.139
PCNA PCNA: Proliferating cell nuclear antigen 0.029 0.046
SYMPK SYMPK, SPK: Symplekin 0.029 0.046
LIG1 LIG1: DNA ligase 1 0.029 0.046
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.032
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.032
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.029 0.069
RUNX1 N/A 0.029 0.029
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.046
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.046
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.029
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.032
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.046
FZR1 N/A 0.029 0.038
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.029 0.139
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.029 0.046
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.032
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.029 0.114
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.029 0.139
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.029 0.063
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.029 0.063
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.046
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.038
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.086
POLB POLB: DNA polymerase beta 0.029 0.029
KIAA0690 N/A 0.029 0.029
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
IRF7 N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
WDR54 N/A 0.028 0.083
C20orf18 N/A 0.028 0.052
DSP DSP: Desmoplakin 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.083
CABLES1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
SNRPB N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.165
ZNF265 N/A 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.083
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.083
HDAC8 N/A 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.083
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.083
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.083
DUSP15 N/A 0.028 0.028
AXIN1 0.028 0.049
UHRF1 0.028 0.052
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.083
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
PHLDB2 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.083
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.083
PPEF1 N/A 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
KIF1B N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CORO6 N/A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.083
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.083
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
KRAS N/A 0.0278 0.108
FOXL2 FOXL2: Forkhead box protein L2 0.028 0.097
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.097
RFX1 RFX1: MHC class II regulatory factor RFX1 0.028 0.049
TRRAP N/A 0.026 0.052
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.052
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.062
TCF7L2 N/A 0.026 0.026
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.0425
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.026 0.077
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.052
EMD EMD, EDMD, STA: Emerin 0.026 0.052
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.027
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.032
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.036
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.032
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.127
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.032
KIF23 N/A 0.026 0.0425
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.0425
ESPL1 N/A 0.026 0.0425
CEP170 CEP170, FAM68A, KAB, KIAA0470: Centrosomal protein of 170 kDa 0.026 0.026
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.075
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.148
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.075
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.075
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.148
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.075
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
TCEA1 N/A 0.025 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.075
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.075
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
HTATIP N/A 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.075
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
SEC13L1 N/A 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
C20orf77 N/A 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.036
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
BRD4 N/A 0.025 0.047
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.075
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.075
GRK6 N/A 0.025 0.025
NUP98 N/A 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.098
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RNF20 0.025 0.025
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.075
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
SON 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.050
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.075
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
ATXN2L N/A 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.075
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
FLJ23436 N/A 0.025 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
NIPBL N/A 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
CAMK2A N/A 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
NES N/A 0.025 0.028
KCTD1 0.025 0.025
HDAC7A N/A 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
DIDO1 N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.075
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.098
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.075
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
0.299
Total Score 27.80