The interaction score between RFC4 and MSH2 is 5.63.
This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins
The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.
| Feature | Evidence | Score (?) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene Expression | Pearson's Correlation between RFC4 and MSH2 = 0.89 The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596. |
0.027 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Orthology |
The Inparalog Score is calculated by InParanoid The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation. |
2.23E-3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Domains | No domains were used in calculating likelihood of interaction | N/A | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Post-translational Modifications | No PTMs were used in calculating likelihood of interaction | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Localisation | No localisation data was used in calculating likelihood of interaction | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Transitive Score |
The common interactors between RFC4 and MSH2 that are considered by the Transitive module are listed below. The Scores listed are the values used by the transitive module to calculate the final interaction Score between RFC4 andMSH2. The values listed are therefore not the final Score value for the listed interactions. With a Score value ≥0.025 , RFC4 has 123 interactors and MSH2 has 61 interactors of which there are 15 common interactors.
|
0.572 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total Score | 5.63 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||