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Evidence of Interaction Between RFC4 and ASF1B

The interaction score between RFC4 and ASF1B is 1.86.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between RFC4 and ASF1B = 0.84

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027
Orthology
OrganismRFC4 OrthologueASF1B OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YJR068W 1 YJL115W 1
  • AffinityCaptureWestern

Get References From PubMed

worm P53016 1 Q17603 1
worm P53016 1 Q19326 0.719
fly Q9VX15 1 Q9V464 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593
Domains No domains were used in calculating likelihood of interaction 8.25E-4
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: RFC4

LocalisationReference
Nucleoplasm HPRD

Protein: ASF1B

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between RFC4 and ASF1B that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between RFC4 andASF1B. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , RFC4 has 123 interactors and ASF1B has 45 interactors of which there are 13 common interactors.

Common InteractorName of Common InteractorScore for RFC4-Interactor (?)Score for ASF1B-Interactor (?)
RFC5 RFC5: Replication factor C subunit 5 691.00 2.15
RFC2 RFC2: Replication factor C subunit 2 62.80 0.196
RFC1 N/A 9.26 1.10
RPA1 RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit 0.0968 1.10
TPX2 TPX2, C20orf1, C20orf2, DIL2, HCA519: Targeting protein for Xklp2 0.027 0.027
HMMR HMMR: Hyaluronan-mediated motility receptor 0.027 0.027
MCM10 N/A 0.027 0.027
C22orf18 N/A 0.027 0.027
RAD51AP1 N/A 0.027 0.027
ZWINT N/A 0.027 0.027
GMNN GMNN: Geminin 0.027 0.027
SPAG5 SPAG5: Sperm-associated antigen 5 0.027 0.027
CDCA8 CDCA8, PESCRG3: Borealin 0.027 0.027
2.15E-3
Total Score 1.86