Predicted interactions involving protein MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 (IPI00184330) that score above 0.125

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module Score	Databases
	Where interaction is observed in another database a link is provided: - BIND - DIP - HPRD O - OPHID

Protein 1 (?)	Protein 2 (?)	Name of Protein 2	Module Scores (?)				Scores (?)	Evidence (?)	Database (?)
MCM2	MCM4	MCM4, CDC21: DNA replication licensing factor MCM4					2.96E5	Evidence
MCM2	MCM3	MCM3: DNA replication licensing factor MCM3					2.96E5	Evidence	O
MCM2	CDC6	CDC6, CDC18L: Cell division control protein 6 homolog					9.88E4	Evidence	O
MCM2	MCM7	MCM7, CDC47, MCM2: DNA replication licensing factor MCM7					4.78E4	Evidence
MCM2	MCM5	MCM5, CDC46: DNA replication licensing factor MCM5					4.78E4	Evidence	O
MCM2	RPA1	RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit					1.59E4	Evidence	O
MCM2	MCM6	MCM6: DNA replication licensing factor MCM6					1.59E4	Evidence	O
MCM2	CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase					1.46E4	Evidence
MCM2	CCNB1	Cyclin B1					372.0	Evidence
MCM2	ORC5L	ORC5L: Origin recognition complex subunit 5					341.0	Evidence	O
MCM2	PCNA	PCNA: Proliferating cell nuclear antigen					189.0	Evidence
MCM2	ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1					174.0	Evidence	O
MCM2	CDK2	CDK2: Cell division protein kinase 2					117.0	Evidence
MCM2	RB1	RB1: Retinoblastoma-associated protein					117.0	Evidence
MCM2	BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein					117.0	Evidence
MCM2	WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase					105.0	Evidence
MCM2	BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein					105.0	Evidence
MCM2	CCNF	CCNF: G2/mitotic-specific cyclin-F					67.20	Evidence
MCM2	CSDA	CSDA, DBPA: DNA-binding protein A					62.90	Evidence
MCM2	CDK4	CDK4: Cell division protein kinase 4					61.50	Evidence	O
MCM2	CCNA2	CCNA2, CCN1, CCNA: Cyclin-A2					60.20	Evidence
MCM2	GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB					51.60	Evidence
MCM2	RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit					51.50	Evidence
MCM2	PLK4	PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4					47.30	Evidence
MCM2	CDC45L	CDC45L, CDC45L2, UNQ374/PRO710: CDC45-related protein					44.90	Evidence
MCM2	BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5					36.00	Evidence
MCM2	VCP	VCP: Transitional endoplasmic reticulum ATPase					34.00	Evidence
MCM2	PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1					33.90	Evidence
MCM2	SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2					33.40	Evidence
MCM2	HDAC3	HDAC3: Histone deacetylase 3					29.50	Evidence
MCM2	NPM1	NPM1, NPM: Nucleophosmin					29.50	Evidence
MCM2	TP53	TP53, P53: Cellular tumor antigen p53					28.80	Evidence
MCM2	ORC2L	ORC2L, ORC2: Origin recognition complex subunit 2					28.2	Evidence	O
MCM2	ORC6L	ORC6L: Origin recognition complex subunit 6					28.2	Evidence	O
MCM2	TFDP1	TFDP1, DP1: Transcription factor Dp-1					28.2	Evidence
MCM2	SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6					26.90	Evidence
MCM2	POLR2A	POLR2A: Uncharacterized protein POLR2A					26.00	Evidence
MCM2	SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4					25.00	Evidence
MCM2	CCNH	CCNH: Cyclin-H					23.70	Evidence
MCM2	HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14					19.90	Evidence
MCM2	PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1					19.90	Evidence
MCM2	RPS6KB1	N/A					19.90	Evidence
MCM2	HDAC2	HDAC2: Histone deacetylase 2					17.80	Evidence
MCM2	RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1					17.60	Evidence
MCM2	TCOF1	N/A					16.10	Evidence
MCM2	CCND1	CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1					15.30	Evidence
MCM2	AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like					14.40	Evidence
MCM2	SCYE1	SCYE1, EMAP2: Multisynthetase complex auxiliary component p43 [Contains: Endothe					13.70	Evidence
MCM2	ARFGAP1	N/A					11.80	Evidence
MCM2	MUTYH	N/A					11.50	Evidence
MCM2	STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta					10.70	Evidence
MCM2	DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B					10.70	Evidence
MCM2	TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain					10.60	Evidence
MCM2	SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2					10.60	Evidence
MCM2	CRSP2	MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol					8.72	Evidence
MCM2	PHB2	PHB2, BAP, REA: Prohibitin-2					8.24	Evidence
MCM2	GMNN	GMNN: Geminin					7.42	Evidence
MCM2	HIVEP1	N/A					7.39	Evidence
MCM2	MTF1	MTF1: Metal regulatory transcription factor 1					6.62	Evidence
MCM2	AURKB	AURKB, AIK2, AIM1, ARK2, STK12: Serine/threonine-protein kinase 12					6.35	Evidence
MCM2	KIAA0101	PAF, KIAA0101, L5, NS5ATP9: PCNA-associated factor					6.29	Evidence
MCM2	RECQL	RECQL, RECQL1: ATP-dependent DNA helicase Q1					6.16	Evidence
MCM2	TRAF2	TRAF2, TRAP3: TNF receptor-associated factor 2					6.08	Evidence
MCM2	GEMIN5	GEMIN5: Gem-associated protein 5					5.73	Evidence
MCM2	BCOR	N/A					5.73	Evidence
MCM2	CDC25A	CDC25A: M-phase inducer phosphatase 1					5.73	Evidence
MCM2	PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2					5.73	Evidence
MCM2	NUP98	N/A					5.73	Evidence
MCM2	TCEA1	N/A					5.73	Evidence
MCM2	DBF4	DBF4, ASK: Protein DBF4 homolog					5.73	Evidence
MCM2	HAT1	HAT1: Histone acetyltransferase type B catalytic subunit					5.64	Evidence	O
MCM2	OBFC1	OBFC1: Oligonucleotide/oligosaccharide-binding fold-containing protein 1					5.63	Evidence
MCM2	CCND2	CCND2: G1/S-specific cyclin-D2					5.30	Evidence
MCM2	DIAPH1	Diaphanous 1					5.28	Evidence
MCM2	GIT1	GIT1: ARF GTPase-activating protein GIT1					5.28	Evidence
MCM2	DDX1	DDX1: ATP-dependent RNA helicase DDX1					5.24	Evidence
MCM2	DDX18	DDX18: ATP-dependent RNA helicase DDX18					5.23	Evidence
MCM2	CDT1	CDT1: DNA replication factor Cdt1					5.13	Evidence
MCM2	ID2	ID2: DNA-binding protein inhibitor ID-2					4.77	Evidence
MCM2	KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13					4.55	Evidence
MCM2	CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1					4.46	Evidence
MCM2	FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn					4.28	Evidence
MCM2	RPA3	RPA3, REPA3, RPA14: Replication protein A 14 kDa subunit					3.70	Evidence	O
MCM2	NEDD4	NEDD4: Uncharacterized protein NEDD4					3.47	Evidence
MCM2	ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174					3.47	Evidence
MCM2	CAMK2A	N/A					3.47	Evidence
MCM2	ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A					3.47	Evidence
MCM2	CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi					2.89	Evidence
MCM2	HMGA2	HMGA2, HMGIC: High mobility group protein HMGI-C					2.89	Evidence
MCM2	ABCD3	ABCD3, PMP70, PXMP1: ATP-binding cassette sub-family D member 3					2.74	Evidence
MCM2	CASP2	CASP2, ICH1, NEDD2: Caspase-2 precursor					2.70	Evidence
MCM2	CREBBP	CREBBP, CBP: CREB-binding protein					2.10	Evidence
MCM2	RP2	RP2: Protein XRP2					2.05	Evidence
MCM2	SH2D3A	SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A					1.98	Evidence
MCM2	C10orf117	NOC3L, AD24, C10orf117, FAD24: Nucleolar complex protein 3 homolog					1.82	Evidence
MCM2	RNF138	N/A					1.78	Evidence
MCM2	WRNIP1	WRNIP1, WHIP: ATPase WRNIP1					1.78	Evidence
MCM2	ORC4L	ORC4L: Origin recognition complex subunit 4					1.71	Evidence
MCM2	POLE	POLE, POLE1: DNA polymerase epsilon catalytic subunit A					1.57	Evidence
MCM2	LIAS	LIAS, LAS, HUSSY-01: Lipoic acid synthetase, mitochondrial precursor					1.10	Evidence	O
MCM2	TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha					0.797	Evidence
MCM2	E2F1	E2F1, RBBP3: Transcription factor E2F1					0.738	Evidence
MCM2	HMGB2	HMGB2, HMG2: High mobility group protein B2					0.715	Evidence
MCM2	EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1					0.66	Evidence
MCM2	ORC3L	ORC3L, LATHEO: Origin recognition complex subunit 3					0.632	Evidence
MCM2	MCM10	MCM10, PRO2249: Protein MCM10 homolog					0.593	Evidence
MCM2	MSH3	MSH3, DUC1, DUG: DNA mismatch repair protein Msh3					0.472	Evidence
MCM2	CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1					0.445	Evidence
MCM2	VRK1	VRK1: Serine/threonine-protein kinase VRK1					0.445	Evidence
MCM2	AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6					0.445	Evidence
MCM2	SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1					0.445	Evidence
MCM2	DNMT1	DNMT1, AIM, DNMT: DNA					0.445	Evidence
MCM2	EFNB1	EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor					0.438	Evidence
MCM2	ATAD2	ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2					0.435	Evidence
MCM2	YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1					0.4	Evidence
MCM2	EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2					0.4	Evidence
MCM2	GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha					0.4	Evidence
MCM2	LHB	LHB: Lutropin subunit beta precursor					0.395	Evidence
MCM2	ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1					0.367	Evidence
MCM2	RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2					0.367	Evidence
MCM2	PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase					0.323	Evidence
MCM2	YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic					0.323	Evidence
MCM2	EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon					0.323	Evidence
MCM2	MTA1	MTA1: Metastasis-associated protein MTA1					0.323	Evidence
MCM2	NEO1	NEO1, NGN: Neogenin precursor					0.318	Evidence
MCM2	ESPL1	N/A					0.265	Evidence
MCM2	CENPA	CENPA: Histone H3-like centromeric protein A					0.265	Evidence
MCM2	MKI67	MKI67: Antigen KI-67					0.265	Evidence
MCM2	EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1					0.265	Evidence
MCM2	ELF1	ELF1: ETS-related transcription factor Elf-1					0.265	Evidence
MCM2	PSMC1	PSMC1: 26S protease regulatory subunit 4					0.263	Evidence
MCM2	PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7					0.263	Evidence
MCM2	TRIP13	TRIP13: Thyroid receptor-interacting protein 13					0.263	Evidence
MCM2	CBX3	CBX3: Chromobox protein homolog 3					0.237	Evidence
MCM2	BARD1	BARD1: BRCA1-associated RING domain protein 1					0.237	Evidence
MCM2	NUP153	N/A					0.237	Evidence
MCM2	SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1					0.237	Evidence
MCM2	SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos					0.237	Evidence
MCM2	CDC20	CDC20: Cell division cycle protein 20 homolog					0.237	Evidence
MCM2	KIF11	N/A					0.237	Evidence
MCM2	LMNB1	LMNB1, LMN2, LMNB: Lamin-B1					0.237	Evidence
MCM2	CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3					0.237	Evidence
MCM2	LIG1	LIG1: DNA ligase 1					0.237	Evidence
MCM2	POLA2	POLA2: DNA polymerase subunit alpha B					0.237	Evidence
MCM2	H2AFX	H2AFX, H2AX: Histone H2A.x					0.237	Evidence
MCM2	ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb					0.237	Evidence
MCM2	MYBL2	MYBL2, BMYB: Myb-related protein B					0.237	Evidence
MCM2	SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1					0.237	Evidence
MCM2	ETV6	ETV6, TEL, TEL1: Transcription factor ETV6					0.237	Evidence
MCM2	FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A					0.237	Evidence
MCM2	MDN1	MDN1, KIAA0301: Midasin					0.237	Evidence
MCM2	EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4					0.237	Evidence
MCM2	RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G					0.233	Evidence
MCM2	CCNB2	CCNB2: G2/mitotic-specific cyclin-B2					0.228	Evidence	O
MCM2	TBP	TBP, GTF2D1, TF2D, TFIID: TATA-box-binding protein					0.225	Evidence	O
MCM2	DDX21	DDX21: Nucleolar RNA helicase 2					0.225	Evidence
MCM2	DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46					0.225	Evidence
MCM2	CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4					0.225	Evidence
MCM2	GTF2F2	N/A					0.217	Evidence
MCM2	ERG	ERG: Transcriptional regulator ERG					0.217	Evidence
MCM2	H1FX	H1FX: Histone H1x					0.217	Evidence
MCM2	FOXJ2	FOXJ2, FHX: Forkhead box protein J2					0.217	Evidence
MCM2	FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1					0.212	Evidence
MCM2	SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10					0.21	Evidence
MCM2	HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F					0.21	Evidence
MCM2	ELAVL1	ELAVL1, HUR: ELAV-like protein 1					0.21	Evidence
MCM2	CSNK2A1	CSNK2A1: CSNK2A1 protein					0.21	Evidence
MCM2	SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q					0.21	Evidence
MCM2	EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9					0.21	Evidence
MCM2	SSB	SSB: Lupus La protein					0.21	Evidence
MCM2	SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2					0.21	Evidence
MCM2	OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1					0.21	Evidence
MCM2	SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul					0.203	Evidence
MCM2	KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase					0.203	Evidence
MCM2	KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate					0.203	Evidence
MCM2	HSF1	HSF1, HSTF1: Heat shock factor protein 1					0.195	Evidence
MCM2	RFC5	RFC5: Replication factor C subunit 5					0.18	Evidence
MCM2	RFC4	RFC4: Replication factor C subunit 4					0.18	Evidence
MCM2	RFC3	RFC3: Replication factor C subunit 3					0.18	Evidence
MCM2	ERF	ERF: ETS domain-containing transcription factor ERF					0.165	Evidence
MCM2	IRF3	IRF3: Interferon regulatory factor 3					0.165	Evidence
MCM2	SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor					0.163	Evidence
MCM2	BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172					0.163	Evidence
MCM2	G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1					0.16	Evidence
MCM2	HIST1H1E	HIST1H1E, H1F4: Histone H1.4					0.147	Evidence
MCM2	HSF2	HSF2, HSTF2: Heat shock factor protein 2					0.147	Evidence
MCM2	CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1					0.147	Evidence
MCM2	HIST1H1D	HIST1H1D, H1F3: Histone H1.3					0.147	Evidence
MCM2	SRPR	SRPR: Uncharacterized protein SRPR					0.142	Evidence
MCM2	ELF2	ELF2, NERF: ETS-related transcription factor Elf-2					0.142	Evidence
MCM2	HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP					0.142	Evidence
MCM2	FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1					0.142	Evidence
MCM2	RBM14	RBM14, SIP: RNA-binding protein 14					0.14	Evidence
MCM2	HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0					0.14	Evidence
MCM2	POLR2H	POLR2H: DNA-directed RNA polymerases I, II, and III subunit RPABC3					0.135	Evidence
MCM2	ETS2	ETS2: Protein C-ets-2					0.133	Evidence
MCM2	MTIF2	MTIF2: Translation initiation factor IF-2, mitochondrial precursor					0.13	Evidence
MCM2	HIST1H1C	HIST1H1C, H1F2: Histone H1.2					0.128	Evidence
MCM2	CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1					0.128	Evidence
MCM2	CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1					0.128	Evidence
MCM2	DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8					0.128	Evidence
MCM2	RBL1	RBL1: Retinoblastoma-like protein 1					0.128	Evidence
MCM2	CCNT2	CCNT2: Cyclin-T2					0.128	Evidence
MCM2	C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y					0.128	Evidence
MCM2	FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain					0.128	Evidence
MCM2	WEE1	WEE1: Wee1-like protein kinase					0.128	Evidence
MCM2	TIAL1	TIAL1: Nucleolysin TIAR					0.128	Evidence
MCM2	RBM15	RBM15, OTT: Putative RNA-binding protein 15					0.128	Evidence
MCM2	SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''					0.128	Evidence
MCM2	PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4					0.128	Evidence
MCM2	PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2					0.128	Evidence
MCM2	PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito					0.128	Evidence
MCM2	SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4					0.128	Evidence
MCM2	PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase					0.128	Evidence