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The Barton Group

Predicted interactions involving protein TGFBR1: TGF-beta receptor type-1 precursor (IPI00005733) that score above 1.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
TGFBR1 ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 8.51E3 Evidence
TGFBR1 SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 3.79E3 Evidence O
TGFBR1 SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 3.54E3 Evidence
TGFBR1 SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 3.26E3 Evidence
TGFBR1 RHEB RHEB, RHEB2: GTP-binding protein Rheb precursor 709.0 Evidence
TGFBR1 TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 336.0 Evidence O
TGFBR1 BMP5 BMP5: Bone morphogenetic protein 5 precursor 93.50 Evidence
TGFBR1 BMP8B BMP8B, BMP8: Bone morphogenetic protein 8B precursor 74.60 Evidence
TGFBR1 INHBA INHBA: Inhibin beta A chain precursor 60.40 Evidence
TGFBR1 INHBB INHBB: Inhibin beta B chain precursor 60.40 Evidence
TGFBR1 BMP6 BMP6, VGR: Bone morphogenetic protein 6 precursor 60.40 Evidence
TGFBR1 RRAS RRAS: Ras-related protein R-Ras precursor 37.40 Evidence
TGFBR1 TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 22.20 Evidence
TGFBR1 FADD FADD, MORT1: Protein FADD 17.50 Evidence
TGFBR1 SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 13.90 Evidence
TGFBR1 PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 12.70 Evidence
TGFBR1 VAV1 VAV1, VAV: Proto-oncogene vav 12.40 Evidence
TGFBR1 SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 11.60 Evidence
TGFBR1 PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 11.60 Evidence
TGFBR1 CDC25A CDC25A: M-phase inducer phosphatase 1 11.60 Evidence
TGFBR1 CSK CSK: Tyrosine-protein kinase CSK 10.70 Evidence
TGFBR1 CRKL CRKL: Crk-like protein 10.70 Evidence
TGFBR1 ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 10.10 Evidence O
TGFBR1 MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 9.92 Evidence
TGFBR1 RAB3A RAB3A: Ras-related protein Rab-3A 9.76 Evidence
TGFBR1 ACVR2A ACVR2A, ACVR2: Activin receptor type-2A precursor 9.16 Evidence
TGFBR1 DOK1 DOK1: Docking protein 1 8.7 Evidence
TGFBR1 CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 8.7 Evidence
TGFBR1 RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 8.7 Evidence
TGFBR1 JAK2 JAK2: Tyrosine-protein kinase JAK2 8.03 Evidence
TGFBR1 RAB6C RAB6C, WTH3: Ras-related protein Rab-6C 7.82 Evidence
TGFBR1 FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 7.73 Evidence
TGFBR1 GAB2 N/A 7.71 Evidence
TGFBR1 STK38 STK38, NDR1: Serine/threonine-protein kinase 38 7.55 Evidence
TGFBR1 CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 6.81 Evidence
TGFBR1 SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 6.78 Evidence
TGFBR1 PRKCI PRKCI, DXS1179E: Protein kinase C iota type 6.63 Evidence
TGFBR1 AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 6.12 Evidence
TGFBR1 F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 5.89 Evidence
TGFBR1 MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 5.87 Evidence
TGFBR1 CNN2 CNN2: Calponin-2 5.87 Evidence
TGFBR1 MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 5.87 Evidence
TGFBR1 PSD TYL: TYL protein 5.84 Evidence
TGFBR1 PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 5.84 Evidence
TGFBR1 RAB33A RAB33A, RABS10: Ras-related protein Rab-33A 5.83 Evidence
TGFBR1 CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 5.83 Evidence
TGFBR1 CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 5.62 Evidence
TGFBR1 ACVRL1 ACVRL1, ACVRLK1, ALK1: Serine/threonine-protein kinase receptor R3 precursor 5.04 Evidence O
TGFBR1 RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 4.86 Evidence
TGFBR1 CREBBP CREBBP, CBP: CREB-binding protein 4.84 Evidence
TGFBR1 DUSP14 DUSP14, MKP6: Dual specificity protein phosphatase 14 4.71 Evidence
TGFBR1 IRF3 IRF3: Interferon regulatory factor 3 4.65 Evidence
TGFBR1 BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 4.38 Evidence
TGFBR1 RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 4.35 Evidence O
TGFBR1 MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 4.28 Evidence
TGFBR1 NEK6 NEK6: Serine/threonine-protein kinase Nek6 4.28 Evidence O
TGFBR1 SF3A1 SF3A1, SAP114: Splicing factor 3 subunit 1 4.16 Evidence
TGFBR1 KIT KIT: Mast/stem cell growth factor receptor precursor 4.03 Evidence
TGFBR1 PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 4.02 Evidence
TGFBR1 RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 3.94 Evidence
TGFBR1 EEA1 EEA1, ZFYVE2: Early endosome antigen 1 3.92 Evidence
TGFBR1 FIGF FIGF, VEGFD: Vascular endothelial growth factor D precursor 3.92 Evidence
TGFBR1 MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 3.92 Evidence
TGFBR1 STIP1 STIP1: Stress-induced-phosphoprotein 1 3.86 Evidence
TGFBR1 CIITA CIITA, MHC2TA: MHC class II transactivator 3.86 Evidence
TGFBR1 DUSP21 DUSP21, LMWDSP21: Dual specificity protein phosphatase 21 3.81 Evidence
TGFBR1 NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 3.77 Evidence
TGFBR1 RBL1 RBL1: Retinoblastoma-like protein 1 3.61 Evidence
TGFBR1 PRKCG PRKCG, PKCG: Protein kinase C gamma type 3.46 Evidence
TGFBR1 IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 3.46 Evidence
TGFBR1 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 3.46 Evidence
TGFBR1 GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 3.32 Evidence
TGFBR1 HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 3.32 Evidence
TGFBR1 DUSP13 DUSP13, TMDP: Dual specificity protein phosphatase 13 3.3 Evidence
TGFBR1 DCN DCN: Decorin precursor 3.28 Evidence
TGFBR1 CDK4 CDK4: Cell division protein kinase 4 3.19 Evidence O
TGFBR1 HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 3.19 Evidence
TGFBR1 FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 3.12 Evidence
TGFBR1 PZP PZP: Pregnancy zone protein precursor 3.02 Evidence
TGFBR1 CDK2 CDK2: Cell division protein kinase 2 3.00 Evidence
TGFBR1 KLK3 KLK3, APS: Prostate-specific antigen precursor 2.93 Evidence
TGFBR1 CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 2.69 Evidence
TGFBR1 NUP214 N/A 2.65 Evidence
TGFBR1 STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 2.49 Evidence
TGFBR1 RNASE2 RNASE2, EDN, RNS2: Non-secretory ribonuclease precursor 2.44 Evidence
TGFBR1 CSNK2A1 CSNK2A1: CSNK2A1 protein 2.43 Evidence
TGFBR1 NUAK1 NUAK1, ARK5, KIAA0537: NUAK family SNF1-like kinase 1 2.15 Evidence
TGFBR1 RRAS2 RRAS2, TC21: Ras-related protein R-Ras2 precursor 2.06 Evidence
TGFBR1 CHC1 RCC1: RCC1-I (Fragment) 2.05 Evidence
TGFBR1 TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 2.05 Evidence
TGFBR1 RANBP1 RANBP1: Ran-specific GTPase-activating protein 1.94 Evidence
TGFBR1 HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 1.93 Evidence
TGFBR1 THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 1.93 Evidence
TGFBR1 CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 1.93 Evidence
TGFBR1 SPARC SPARC, ON: SPARC precursor 1.93 Evidence
TGFBR1 RAB38 RAB38: Ras-related protein Rab-38 1.91 Evidence O
TGFBR1 FAM43A N/A 1.91 Evidence
TGFBR1 RANBP3 RANBP3: Ran-binding protein 3 1.71 Evidence
TGFBR1 AXIN1 1.71 Evidence
TGFBR1 CAMK2A N/A 1.53 Evidence
TGFBR1 RIT1 RIT1, RIBB, RIT, ROC1: GTP-binding protein Rit1 1.47 Evidence
TGFBR1 RAB35 RAB35, RAB1C, RAY: Ras-related protein Rab-35 1.46 Evidence
TGFBR1 XPO1 XPO1, CRM1: Exportin-1 1.32 Evidence
TGFBR1 UBA52 UBA52, UBCEP2: 60S ribosomal protein L40 1.30 Evidence
TGFBR1 ARL4D ARL4D, ARF4L: ADP-ribosylation factor-like protein 4D 1.30 Evidence O
TGFBR1 SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 1.29 Evidence
TGFBR1 FGD5 FGD5, ZFYVE23: FYVE, RhoGEF and PH domain-containing protein 5 1.29 Evidence
TGFBR1 SMAD9 SMAD9, MADH6, MADH9: Mothers against decapentaplegic homolog 9 1.29 Evidence
TGFBR1 MCM3 MCM3: DNA replication licensing factor MCM3 1.25 Evidence
TGFBR1 JUNB JUNB: Transcription factor jun-B 1.25 Evidence
TGFBR1 JUND JUND: Transcription factor jun-D 1.25 Evidence
TGFBR1 PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 1.14 Evidence
TGFBR1 CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 1.14 Evidence
TGFBR1 YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 1.14 Evidence
TGFBR1 TOB1 TOB1, TOB, TROB1: Protein Tob1 1.11 Evidence
TGFBR1 JUN JUN: Transcription factor AP-1 1.1 Evidence
TGFBR1 VDR VDR, NR1I1: Vitamin D3 receptor 1.1 Evidence
TGFBR1 DUPD1 DUPD1, DUSP27: Dual specificity phosphatase DUPD1 1.07 Evidence
TGFBR1 TTN N/A 1.00 Evidence
TGFBR1 ACTG1 ACTB: Actin, cytoplasmic 1 1.00 Evidence