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The Barton Group

Predicted interactions involving protein SH2B3, LNK: SH2B adapter protein 3 (IPI00010821) that score above 1.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
LNK FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 299.0 Evidence
LNK JAK2 JAK2: Tyrosine-protein kinase JAK2 299.0 Evidence
LNK ZAP70 ZAP70: Uncharacterized protein ZAP70 299.0 Evidence
LNK PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 224.0 Evidence
LNK FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 224.0 Evidence
LNK KIT KIT: Mast/stem cell growth factor receptor precursor 224.0 Evidence
LNK CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 224.0 Evidence
LNK LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 119.0 Evidence O
LNK ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 119.0 Evidence
LNK PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 119.0 Evidence
LNK CSK CSK: Tyrosine-protein kinase CSK 119.0 Evidence
LNK SYK SYK: Tyrosine-protein kinase SYK 119.0 Evidence
LNK EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 89.20 Evidence
LNK TEK TEK, TIE2: Angiopoietin-1 receptor precursor 89.20 Evidence
LNK CRKL CRKL: Crk-like protein 37.80 Evidence
LNK STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 37.80 Evidence
LNK TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 19.70 Evidence
LNK PRKCE PRKCE, PKCE: Protein kinase C epsilon type 19.70 Evidence
LNK SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 19.70 Evidence
LNK MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 19.70 Evidence
LNK WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 19.70 Evidence
LNK MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 19.70 Evidence
LNK STAT5B STAT5B: Signal transducer and activator of transcription 5B 15.10 Evidence
LNK CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 15.10 Evidence
LNK WASL WASL: Neural Wiskott-Aldrich syndrome protein 15.00 Evidence
LNK PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 15.00 Evidence
LNK SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 15.00 Evidence
LNK CTTN CTTN, EMS1: Src substrate cortactin 15.00 Evidence
LNK PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 15.00 Evidence
LNK APS SH2B2, APS: SH2B adapter protein 2 15.00 Evidence
LNK RASA1 RASA1, RASA: Ras GTPase-activating protein 1 15.00 Evidence
LNK SLA SLA, SLAP, SLAP1: SRC-like-adapter 15.00 Evidence
LNK VAV1 VAV1, VAV: Proto-oncogene vav 15.00 Evidence
LNK SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 15.00 Evidence
LNK TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 13.00 Evidence
LNK CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 13.00 Evidence
LNK SOS1 SOS1: Son of sevenless homolog 1 13.00 Evidence
LNK STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 9.92 Evidence
LNK CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 9.92 Evidence
LNK FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 9.92 Evidence
LNK LCP2 LCP2: Lymphocyte cytosolic protein 2 9.92 Evidence
LNK CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 9.92 Evidence
LNK PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 9.92 Evidence
LNK CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 9.92 Evidence
LNK CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 9.92 Evidence
LNK ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 7.59 Evidence
LNK BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 6.14 Evidence
LNK GRAP GRAP: GRB2-related adapter protein 6.11 Evidence
LNK HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 4.76 Evidence
LNK GRB10 N/A 4.68 Evidence
LNK PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 4.68 Evidence
LNK SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 3.18 Evidence
LNK SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 3.18 Evidence
LNK DEF6 DEF6, IBP: Differentially expressed in FDCP 6 2.54 Evidence
LNK CASP3 CASP3, CPP32: Caspase-3 precursor 2.54 Evidence
LNK FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 1.13 Evidence
LNK TXK TXK, PTK4: Tyrosine-protein kinase TXK 1.13 Evidence
LNK PTK6 PTK6, BRK: Tyrosine-protein kinase 6 1.13 Evidence
LNK ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.13 Evidence
LNK FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 1.13 Evidence
LNK LYN LYN: Tyrosine-protein kinase Lyn 1.13 Evidence
LNK FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 1.13 Evidence
LNK PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 1.13 Evidence
LNK SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.13 Evidence
LNK TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 1.13 Evidence
LNK BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 1.13 Evidence
LNK MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 1.13 Evidence
LNK TESK1 TESK1: Dual specificity testis-specific protein kinase 1 1.13 Evidence
LNK YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 1.13 Evidence
LNK BMX N/A 1.13 Evidence
LNK TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 1.13 Evidence
LNK JAK1 1.13 Evidence
LNK HCK N/A 1.13 Evidence
LNK INSL3 JAK3: Tyrosine-protein kinase JAK3 1.13 Evidence
LNK ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 Evidence