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The Barton Group

Predicted interactions involving protein PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta (IPI00011736) that score above 1.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
PIK3R2 PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 7.21E4 Evidence O
PIK3R2 CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 5.72E4 Evidence O
PIK3R2 INSR INSR: Insulin receptor precursor 5.39E4 Evidence
PIK3R2 FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 268.0 Evidence O
PIK3R2 TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 246.0 Evidence
PIK3R2 FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 185.0 Evidence
PIK3R2 TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 178.0 Evidence
PIK3R2 JAK2 JAK2: Tyrosine-protein kinase JAK2 178.0 Evidence
PIK3R2 ZAP70 ZAP70: Uncharacterized protein ZAP70 178.0 Evidence
PIK3R2 YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 158.0 Evidence
PIK3R2 PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 149.0 Evidence
PIK3R2 SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 135.0 Evidence
PIK3R2 KIT KIT: Mast/stem cell growth factor receptor precursor 132.0 Evidence O
PIK3R2 EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 121.0 Evidence
PIK3R2 ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 121.0 Evidence
PIK3R2 LYN LYN: Tyrosine-protein kinase Lyn 108.0 Evidence
PIK3R2 JAK1 108.0 Evidence
PIK3R2 PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 106.0 Evidence
PIK3R2 ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 106.0 Evidence
PIK3R2 KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 72.10 Evidence
PIK3R2 SYK SYK: Tyrosine-protein kinase SYK 71.10 Evidence
PIK3R2 CSK CSK: Tyrosine-protein kinase CSK 71.10 Evidence
PIK3R2 ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 70.50 Evidence
PIK3R2 BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 70.10 Evidence
PIK3R2 TEK TEK, TIE2: Angiopoietin-1 receptor precursor 66.50 Evidence
PIK3R2 FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 63.20 Evidence
PIK3R2 ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 62.10 Evidence O
PIK3R2 GRK1 GRK1, RHOK: Rhodopsin kinase precursor 43.60 Evidence
PIK3R2 GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 33.90 Evidence
PIK3R2 RASA1 RASA1, RASA: Ras GTPase-activating protein 1 33.90 Evidence
PIK3R2 GAB1 GAB1: GRB2-associated-binding protein 1 28.20 Evidence
PIK3R2 SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 26.40 Evidence
PIK3R2 APS SH2B2, APS: SH2B adapter protein 2 25.3 Evidence
PIK3R2 CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 25.3 Evidence
PIK3R2 DAB2 DAB2, DOC2: Disabled homolog 2 25.3 Evidence
PIK3R2 NCK1 NCK1, NCK: Cytoplasmic protein NCK1 22.60 Evidence
PIK3R2 GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 22.60 Evidence
PIK3R2 STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 22.30 Evidence
PIK3R2 PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 22.30 Evidence
PIK3R2 CRKL CRKL: Crk-like protein 22.20 Evidence O
PIK3R2 CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 20.50 Evidence O
PIK3R2 NEK6 NEK6: Serine/threonine-protein kinase Nek6 20.50 Evidence
PIK3R2 SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 20.50 Evidence
PIK3R2 STAT3 20.50 Evidence
PIK3R2 RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 20.00 Evidence
PIK3R2 RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 20.00 Evidence
PIK3R2 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 20.00 Evidence
PIK3R2 CTTN CTTN, EMS1: Src substrate cortactin 17.30 Evidence
PIK3R2 NCK2 NCK2: Cytoplasmic protein NCK2 16.00 Evidence
PIK3R2 PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 15.00 Evidence
PIK3R2 LNK SH2B3, LNK: SH2B adapter protein 3 15.00 Evidence
PIK3R2 STAT5B STAT5B: Signal transducer and activator of transcription 5B 13.20 Evidence
PIK3R2 PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 13.20 Evidence
PIK3R2 PRKCE PRKCE, PKCE: Protein kinase C epsilon type 13.2 Evidence
PIK3R2 IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 12.10 Evidence
PIK3R2 S100A16 S100A16, AAG13: Protein S100-A16 11.90 Evidence
PIK3R2 WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 11.80 Evidence
PIK3R2 WASPIP N/A 11.80 Evidence
PIK3R2 GRB10 N/A 11.70 Evidence
PIK3R2 ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 11.60 Evidence
PIK3R2 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 11.60 Evidence
PIK3R2 SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 10.50 Evidence
PIK3R2 MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 10.10 Evidence
PIK3R2 SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 10.00 Evidence
PIK3R2 SLA SLA, SLAP, SLAP1: SRC-like-adapter 10.00 Evidence
PIK3R2 PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 9.32 Evidence
PIK3R2 DOK1 DOK1: Docking protein 1 9.0 Evidence
PIK3R2 VAV1 VAV1, VAV: Proto-oncogene vav 9.0 Evidence
PIK3R2 HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 9.0 Evidence
PIK3R2 BLNK BLNK, BASH, SLP65: B-cell linker protein 8.92 Evidence
PIK3R2 SOS1 SOS1: Son of sevenless homolog 1 8.90 Evidence
PIK3R2 WASL WASL: Neural Wiskott-Aldrich syndrome protein 8.86 Evidence
PIK3R2 CD2AP CD2AP: CD2-associated protein 7.99 Evidence
PIK3R2 EPOR EPOR: Erythropoietin receptor precursor 7.40 Evidence
PIK3R2 MSN MSN: Moesin 7.14 Evidence
PIK3R2 PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 6.76 Evidence
PIK3R2 LCP2 LCP2: Lymphocyte cytosolic protein 2 6.62 Evidence
PIK3R2 CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 6.62 Evidence
PIK3R2 CDC25A CDC25A: M-phase inducer phosphatase 1 6.50 Evidence
PIK3R2 BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 6.39 Evidence
PIK3R2 C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 6.37 Evidence
PIK3R2 CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 6.17 Evidence
PIK3R2 IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 5.88 Evidence
PIK3R2 SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 5.04 Evidence O
PIK3R2 SNX12 N/A 5.02 Evidence
PIK3R2 KIR2DL3 KIR2DL3, CD158B2, KIRCL23, NKAT2: Killer cell immunoglobulin-like receptor 2DL3 4.80 Evidence
PIK3R2 MADCAM1 MADCAM1: Mucosal addressin cell adhesion molecule 1 precursor 4.80 Evidence
PIK3R2 MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 4.77 Evidence
PIK3R2 GRB14 GRB14: Growth factor receptor-bound protein 14 4.56 Evidence
PIK3R2 PRKCG PRKCG, PKCG: Protein kinase C gamma type 4.45 Evidence
PIK3R2 GRB7 GRB7: Growth factor receptor-bound protein 7 4.01 Evidence
PIK3R2 GRAP GRAP: GRB2-related adapter protein 3.6 Evidence
PIK3R2 SNX3 N/A 3.33 Evidence
PIK3R2 OPTC OPTC, OPT: Opticin precursor 3.28 Evidence
PIK3R2 PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 3.12 Evidence
PIK3R2 SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 3.05 Evidence
PIK3R2 BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 3.02 Evidence
PIK3R2 IL13RA1 IL13RA1, IL13R, IL13RA: Interleukin-13 receptor alpha-1 chain precursor 2.84 Evidence
PIK3R2 S100A3 S100A3, S100E: Protein S100-A3 2.40 Evidence
PIK3R2 GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 2.19 Evidence
PIK3R2 BMX N/A 2.1 Evidence
PIK3R2 IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 2.0 Evidence
PIK3R2 EFNA1 EFNA1, EPLG1, LERK1, TNFAIP4: Ephrin-A1 precursor 1.96 Evidence
PIK3R2 CREB1 CREB1: cAMP response element-binding protein 1.78 Evidence
PIK3R2 INSL3 JAK3: Tyrosine-protein kinase JAK3 1.72 Evidence
PIK3R2 CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 1.62 Evidence
PIK3R2 SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 1.62 Evidence
PIK3R2 SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 1.53 Evidence
PIK3R2 CDC23 CDC23: Cell division cycle protein 23 homolog 1.52 Evidence
PIK3R2 CASP3 CASP3, CPP32: Caspase-3 precursor 1.5 Evidence
PIK3R2 NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 1.32 Evidence
PIK3R2 PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 1.32 Evidence
PIK3R2 RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 1.23 Evidence
PIK3R2 FLT4 VEGFR3 long form 1.18 Evidence
PIK3R2 EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 1.15 Evidence
PIK3R2 ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.13 Evidence
PIK3R2 TESK1 TESK1: Dual specificity testis-specific protein kinase 1 1.04 Evidence