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The Barton Group

Predicted interactions involving protein PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 (IPI00002538) that score above 2.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
PDPK1 PRKCE PRKCE, PKCE: Protein kinase C epsilon type 33.90 Evidence
PDPK1 MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 33.90 Evidence
PDPK1 RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 20.50 Evidence
PDPK1 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 20.50 Evidence
PDPK1 FRS3 FRS3: Fibroblast growth factor receptor substrate 3 20.50 Evidence
PDPK1 SNCA SNCA, NACP, PARK1: Alpha-synuclein 19.70 Evidence
PDPK1 NEK3 NEK3: Serine/threonine-protein kinase Nek3 19.70 Evidence
PDPK1 SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 19.70 Evidence
PDPK1 MSN MSN: Moesin 17.60 Evidence
PDPK1 PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 17.60 Evidence
PDPK1 MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 17.60 Evidence
PDPK1 PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 17.60 Evidence
PDPK1 FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 17.60 Evidence
PDPK1 RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 17.60 Evidence
PDPK1 DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 17.60 Evidence
PDPK1 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 17.60 Evidence
PDPK1 MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 17.60 Evidence
PDPK1 RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 17.60 Evidence
PDPK1 TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 17.60 Evidence
PDPK1 PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 17.60 Evidence
PDPK1 RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 17.60 Evidence
PDPK1 MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 17.60 Evidence
PDPK1 WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 17.60 Evidence
PDPK1 DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 17.60 Evidence
PDPK1 TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 17.60 Evidence
PDPK1 HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 15.00 Evidence
PDPK1 HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 15.00 Evidence
PDPK1 MCF2 MCF2, DBL: Proto-oncogene DBL 15.00 Evidence
PDPK1 STMN2 STMN2, SCG10, SCGN10: Stathmin-2 13.40 Evidence
PDPK1 GSK3A GSK3A: Glycogen synthase kinase-3 alpha 13.40 Evidence
PDPK1 FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 13.40 Evidence
PDPK1 RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 13.40 Evidence
PDPK1 FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 13.40 Evidence
PDPK1 EEF2K EEF2K: Elongation factor 2 kinase 13.40 Evidence
PDPK1 CSK CSK: Tyrosine-protein kinase CSK 13.40 Evidence
PDPK1 STMN1 STMN1, LAP18, OP18: Stathmin 13.40 Evidence
PDPK1 BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 13.40 Evidence
PDPK1 ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 13.40 Evidence
PDPK1 DOK1 DOK1: Docking protein 1 13.40 Evidence
PDPK1 RRAD RRAD, RAD: GTP-binding protein RAD 13.40 Evidence
PDPK1 TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 11.60 Evidence
PDPK1 SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 11.60 Evidence
PDPK1 SYTL4 Endocrine transmitter regulatory protein 9.96 Evidence
PDPK1 SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 9.96 Evidence
PDPK1 H1FX H1FX: Histone H1x 9.96 Evidence
PDPK1 PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 9.92 Evidence
PDPK1 GABRR1 N/A 9.92 Evidence
PDPK1 GHR GHR: Growth hormone receptor precursor 9.92 Evidence
PDPK1 TLN1 TLN1: Uncharacterized protein TLN1 8.92 Evidence
PDPK1 HSF1 HSF1, HSTF1: Heat shock factor protein 1 8.92 Evidence
PDPK1 JUN JUN: Transcription factor AP-1 8.92 Evidence
PDPK1 MIP MIP, AQP0: Lens fiber major intrinsic protein 8.89 Evidence
PDPK1 PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 8.22 Evidence
PDPK1 CENTA1 CENTA1: Centaurin-alpha 1 8.22 Evidence
PDPK1 ELF1 ELF1: ETS-related transcription factor Elf-1 7.59 Evidence
PDPK1 ETV1 ETV1, ER81: ETS translocation variant 1 7.59 Evidence
PDPK1 NOS1 NOS1: Nitric-oxide synthase, brain 7.59 Evidence
PDPK1 CHAT CHAT: Choline O-acetyltransferase 7.36 Evidence
PDPK1 CCNB1 Cyclin B1 6.82 Evidence
PDPK1 SGK2 SGK2: Serine/threonine-protein kinase Sgk2 6.82 Evidence
PDPK1 PRKCG PRKCG, PKCG: Protein kinase C gamma type 6.82 Evidence
PDPK1 PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 6.82 Evidence
PDPK1 CDK2 CDK2: Cell division protein kinase 2 6.82 Evidence
PDPK1 PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 6.82 Evidence
PDPK1 HIST1H1B HIST1H1B, H1F5: Histone H1.5 6.80 Evidence
PDPK1 TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 6.80 Evidence
PDPK1 PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 6.80 Evidence
PDPK1 LCP1 LCP1, PLS2: Plastin-2 6.80 Evidence
PDPK1 FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 6.80 Evidence
PDPK1 CGA CGA: Glycoprotein hormones alpha chain precursor 6.26 Evidence
PDPK1 GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 6.26 Evidence
PDPK1 KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 6.24 Evidence
PDPK1 PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 6.14 Evidence
PDPK1 GJA1 GJA1, GJAL: Gap junction alpha-1 protein 6.14 Evidence
PDPK1 RAB1B RAB1B: Ras-related protein Rab-1B 5.96 Evidence
PDPK1 FADD FADD, MORT1: Protein FADD 5.87 Evidence
PDPK1 TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 5.87 Evidence
PDPK1 PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 5.73 Evidence
PDPK1 PFKFB2 PFKFB2: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 5.61 Evidence
PDPK1 RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 5.61 Evidence
PDPK1 PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 5.50 Evidence
PDPK1 CDK3 CDK3: Cell division protein kinase 3 5.48 Evidence
PDPK1 CCNB2 CCNB2: G2/mitotic-specific cyclin-B2 5.48 Evidence
PDPK1 GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 5.26 Evidence
PDPK1 GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 5.26 Evidence
PDPK1 SLC4A3 SLC4A3, AE3: Anion exchange protein 3 4.78 Evidence
PDPK1 GJB1 GJB1, CX32: Gap junction beta-1 protein 4.68 Evidence
PDPK1 GJA5 GJA5: Gap junction alpha-5 protein 4.68 Evidence
PDPK1 TPH1 N/A 4.68 Evidence
PDPK1 ATP2B1 N/A 4.48 Evidence
PDPK1 RAP1GA1 N/A 4.48 Evidence
PDPK1 MAFG MAFG: Transcription factor MafG 4.26 Evidence
PDPK1 TH TH, TYH: Tyrosine 3-monooxygenase 4.19 Evidence
PDPK1 IKBKE IKBKE, IKKE, IKKI, KIAA0151: Inhibitor of nuclear factor kappa-B kinase subunit 4.19 Evidence
PDPK1 CDC37 CDC37: Hsp90 co-chaperone Cdc37 4.19 Evidence
PDPK1 CFTR CFTR: Cystic fibrosis transmembrane conductance regulator ATP-binding cassette s 4.03 Evidence
PDPK1 MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 4.01 Evidence
PDPK1 GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 4.01 Evidence
PDPK1 GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 4.01 Evidence
PDPK1 GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 4.01 Evidence
PDPK1 SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 3.65 Evidence
PDPK1 PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 3.65 Evidence
PDPK1 SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 3.65 Evidence
PDPK1 OPRD1 OPRD1, OPRD: Delta-type opioid receptor 3.61 Evidence
PDPK1 GAD2 GAD2, GAD65: Glutamate decarboxylase 2 3.61 Evidence
PDPK1 ZNF579 ZNF579: Zinc finger protein 579 3.34 Evidence
PDPK1 GNB2L1 Lung cancer oncogene 7 3.34 Evidence
PDPK1 ZYX ZYX: Zyxin 3.34 Evidence
PDPK1 NCF4 N/A 3.34 Evidence
PDPK1 AFAP AFAP1, AFAP: Actin filament-associated protein 1 3.34 Evidence
PDPK1 KRT18 KRT18: Uncharacterized protein KRT18 3.34 Evidence
PDPK1 SLC2A2 SLC2A2, GLUT2: Solute carrier family 2, facilitated glucose transporter member 2 3.26 Evidence
PDPK1 ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 3.18 Evidence
PDPK1 PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 3.18 Evidence
PDPK1 IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 3.07 Evidence
PDPK1 RYR2 RYR2: Ryanodine receptor 2 3.07 Evidence
PDPK1 TCEA1 N/A 2.99 Evidence
PDPK1 NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 2.99 Evidence
PDPK1 SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 2.99 Evidence
PDPK1 BUB3 BUB3: Mitotic checkpoint protein BUB3 2.99 Evidence
PDPK1 PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 2.99 Evidence
PDPK1 PARD6G PARD6G, PAR6G: Partitioning defective 6 homolog gamma 2.85 Evidence
PDPK1 HMGCR HMGCR: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2.75 Evidence
PDPK1 LIPE LIPE: Hormone-sensitive lipase 2.75 Evidence
PDPK1 GRIN2B GRIN2B, NMDAR2B: Glutamate [NMDA] receptor subunit epsilon-2 precursor 2.75 Evidence
PDPK1 KCNA2 KCNA2: Potassium voltage-gated channel subfamily A member 2 2.75 Evidence
PDPK1 RYR1 2.75 Evidence
PDPK1 SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 2.54 Evidence
PDPK1 TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 2.54 Evidence
PDPK1 PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 2.54 Evidence
PDPK1 PTBP1 PTBP1: Polypyrimidine tract binding protein 1 2.54 Evidence
PDPK1 DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 2.54 Evidence
PDPK1 SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 2.54 Evidence
PDPK1 ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 2.54 Evidence
PDPK1 GFAP GFAP: Glial fibrillary acidic protein 2.54 Evidence
PDPK1 TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 2.54 Evidence
PDPK1 NR3C1 NR3C1, GRL: Glucocorticoid receptor 2.54 Evidence
PDPK1 PTPN7 N/A 2.54 Evidence
PDPK1 AANAT AANAT, SNAT: Serotonin N-acetyltransferase 2.54 Evidence