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The Barton Group

Predicted interactions involving protein (IPI00298887) that score above 2.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
STAT3 STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 3.40E3 Evidence
STAT3 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 2.89E3 Evidence
STAT3 STAT6 STAT6: Signal transducer and activator of transcription 6 2.69E3 Evidence
STAT3 STAT5B STAT5B: Signal transducer and activator of transcription 5B 1.91E3 Evidence
STAT3 JAK2 JAK2: Tyrosine-protein kinase JAK2 299.0 Evidence
STAT3 TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 299.0 Evidence
STAT3 FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 268.0 Evidence
STAT3 PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 200.0 Evidence
STAT3 PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 200.0 Evidence
STAT3 INSR INSR: Insulin receptor precursor 200.0 Evidence
STAT3 KIT KIT: Mast/stem cell growth factor receptor precursor 200.0 Evidence
STAT3 JAK1 156.0 Evidence
STAT3 SYK SYK: Tyrosine-protein kinase SYK 156.0 Evidence
STAT3 LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 156.0 Evidence
STAT3 SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 156.0 Evidence
STAT3 BMX N/A 156.0 Evidence
STAT3 BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 156.0 Evidence
STAT3 INSL3 JAK3: Tyrosine-protein kinase JAK3 119.0 Evidence
STAT3 ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 119.0 Evidence
STAT3 TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 119.0 Evidence
STAT3 ZAP70 ZAP70: Uncharacterized protein ZAP70 119.0 Evidence
STAT3 PTK6 PTK6, BRK: Tyrosine-protein kinase 6 119.0 Evidence
STAT3 ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 117.0 Evidence
STAT3 ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 117.0 Evidence
STAT3 EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 117.0 Evidence
STAT3 PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 106.0 Evidence
STAT3 LYN LYN: Tyrosine-protein kinase Lyn 106.0 Evidence
STAT3 FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 106.0 Evidence
STAT3 CSK CSK: Tyrosine-protein kinase CSK 106.0 Evidence
STAT3 KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 104.0 Evidence
STAT3 TEK TEK, TIE2: Angiopoietin-1 receptor precursor 89.20 Evidence
STAT3 FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 89.20 Evidence
STAT3 FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 79.90 Evidence
STAT3 FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 79.90 Evidence
STAT3 ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 49.40 Evidence
STAT3 NCK2 NCK2: Cytoplasmic protein NCK2 33.90 Evidence
STAT3 CRKL CRKL: Crk-like protein 33.90 Evidence
STAT3 NCK1 NCK1, NCK: Cytoplasmic protein NCK1 20.50 Evidence
STAT3 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 20.50 Evidence
STAT3 GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 20.50 Evidence
STAT3 PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 20.50 Evidence
STAT3 DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 20.50 Evidence
STAT3 MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 19.70 Evidence
STAT3 APS SH2B2, APS: SH2B adapter protein 2 19.70 Evidence
STAT3 KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 19.00 Evidence
STAT3 STAM2 STAM2: Signal transducing adapter molecule 2 17.60 Evidence
STAT3 WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 17.60 Evidence
STAT3 CSNK2A1 CSNK2A1: CSNK2A1 protein 17.60 Evidence
STAT3 MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 17.60 Evidence
STAT3 RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 17.60 Evidence
STAT3 MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 17.60 Evidence
STAT3 RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 17.60 Evidence
STAT3 DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 17.60 Evidence
STAT3 PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 15.10 Evidence
STAT3 DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 15.10 Evidence
STAT3 PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 15.00 Evidence
STAT3 SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 15.00 Evidence
STAT3 MYO3A MYO3A: Myosin IIIA 15.00 Evidence
STAT3 SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 15.00 Evidence
STAT3 RASA1 RASA1, RASA: Ras GTPase-activating protein 1 15.00 Evidence
STAT3 IRS1 IRS1: Insulin receptor substrate 1 15.00 Evidence
STAT3 SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 15.00 Evidence
STAT3 CTTN CTTN, EMS1: Src substrate cortactin 15.00 Evidence
STAT3 BLNK BLNK, BASH, SLP65: B-cell linker protein 15.00 Evidence
STAT3 CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 13.50 Evidence
STAT3 LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 13.40 Evidence
STAT3 DYRK3 N/A 13.40 Evidence
STAT3 WASPIP N/A 13.40 Evidence
STAT3 AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 13.40 Evidence
STAT3 CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 13.40 Evidence
STAT3 WASL WASL: Neural Wiskott-Aldrich syndrome protein 13.40 Evidence
STAT3 LCP1 LCP1, PLS2: Plastin-2 13.40 Evidence
STAT3 MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 13.40 Evidence
STAT3 PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 13.40 Evidence
STAT3 VAV1 VAV1, VAV: Proto-oncogene vav 13.40 Evidence
STAT3 RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 13.40 Evidence
STAT3 GHR GHR: Growth hormone receptor precursor 13.00 Evidence
STAT3 PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 13.00 Evidence
STAT3 EPOR EPOR: Erythropoietin receptor precursor 13.00 Evidence
STAT3 CCR5 CCR5: CCR5 receptor (Fragment) 13.00 Evidence
STAT3 IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 13.00 Evidence
STAT3 STAT4 STAT4: Signal transducer and activator of transcription 4 12.80 Evidence
STAT3 FOSL2 FOSL2, FRA2: Fos-related antigen 2 11.20 Evidence
STAT3 FOS FOS, G0S7: Proto-oncogene protein c-fos 11.20 Evidence
STAT3 PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 9.92 Evidence
STAT3 CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 9.92 Evidence
STAT3 CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 9.92 Evidence
STAT3 ETS2 ETS2: Protein C-ets-2 9.92 Evidence
STAT3 DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 9.92 Evidence
STAT3 STAT2 STAT2: Signal transducer and activator of transcription 2 9.92 Evidence
STAT3 CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 9.92 Evidence
STAT3 IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 9.92 Evidence
STAT3 HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 9.92 Evidence
STAT3 LCP2 LCP2: Lymphocyte cytosolic protein 2 9.92 Evidence
STAT3 PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 9.92 Evidence
STAT3 CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 9.92 Evidence
STAT3 PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 9.92 Evidence
STAT3 PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 8.92 Evidence
STAT3 SOS1 SOS1: Son of sevenless homolog 1 8.89 Evidence
STAT3 ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 8.89 Evidence
STAT3 PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 8.89 Evidence
STAT3 CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 8.89 Evidence
STAT3 BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 7.59 Evidence
STAT3 CRIP2 CRIP2, CRP2: Cysteine-rich protein 2 7.59 Evidence
STAT3 CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 6.14 Evidence
STAT3 RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 5.61 Evidence
STAT3 CXCR4 CXCR4: C-X-C chemokine receptor type 4 5.28 Evidence
STAT3 HSF1 HSF1, HSTF1: Heat shock factor protein 1 5.26 Evidence
STAT3 CREBBP CREBBP, CBP: CREB-binding protein 5.26 Evidence
STAT3 JUN JUN: Transcription factor AP-1 5.26 Evidence
STAT3 GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 5.26 Evidence
STAT3 CREB1 CREB1: cAMP response element-binding protein 5.26 Evidence
STAT3 BARD1 BARD1: BRCA1-associated RING domain protein 1 4.97 Evidence
STAT3 PHB2 PHB2, BAP, REA: Prohibitin-2 4.76 Evidence
STAT3 HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 4.76 Evidence
STAT3 GRB10 N/A 4.68 Evidence
STAT3 CRK CRK: Proto-oncogene C-crk 4.68 Evidence
STAT3 BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 4.68 Evidence
STAT3 NR3C1 NR3C1, GRL: Glucocorticoid receptor 4.48 Evidence
STAT3 CHGB CHGB, SCG1: Secretogranin-1 precursor 4.48 Evidence
STAT3 RELA RELA, NFKB3: Transcription factor p65 4.48 Evidence
STAT3 TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 4.48 Evidence
STAT3 CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 4.48 Evidence
STAT3 FADD FADD, MORT1: Protein FADD 4.48 Evidence
STAT3 CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 4.26 Evidence
STAT3 ANXA6 ANXA6, ANX6: Annexin A6 4.02 Evidence
STAT3 CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 4.02 Evidence
STAT3 ETS1 ETS1, EWSR2: Protein C-ets-1 4.01 Evidence
STAT3 BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 4.01 Evidence
STAT3 TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 3.64 Evidence
STAT3 CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 3.64 Evidence
STAT3 ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 3.64 Evidence
STAT3 SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 3.31 Evidence
STAT3 VDR VDR, NR1I1: Vitamin D3 receptor 3.26 Evidence
STAT3 MCM3 MCM3: DNA replication licensing factor MCM3 3.26 Evidence
STAT3 NMI NMI: N-myc-interactor 3.18 Evidence
STAT3 RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 3.18 Evidence
STAT3 ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 3.18 Evidence
STAT3 COPA COPA: Coatomer subunit alpha 2.99 Evidence
STAT3 VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 2.54 Evidence
STAT3 NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 2.54 Evidence
STAT3 USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 2.54 Evidence
STAT3 CHUK N/A 2.54 Evidence
STAT3 MAPK7 mitogen-activated protein kinase 7 isoform 1 2.54 Evidence
STAT3 STIP1 STIP1: Stress-induced-phosphoprotein 1 2.54 Evidence
STAT3 ABCF1 N/A 2.54 Evidence
STAT3 DUSP2 DUSP2, PAC1: Dual specificity protein phosphatase 2 2.50 Evidence