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The Barton Group

Predicted interactions involving protein RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 (IPI00300321) that score above 2.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
RPS6KA2 NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 1.67E3 Evidence
RPS6KA2 RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 196.0 Evidence
RPS6KA2 ZAP70 ZAP70: Uncharacterized protein ZAP70 61.60 Evidence
RPS6KA2 DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 33.90 Evidence
RPS6KA2 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 31.10 Evidence
RPS6KA2 EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 25.00 Evidence
RPS6KA2 SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 22.90 Evidence
RPS6KA2 RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 20.50 Evidence
RPS6KA2 DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 20.50 Evidence
RPS6KA2 DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 20.50 Evidence
RPS6KA2 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 20.50 Evidence
RPS6KA2 IRS1 IRS1: Insulin receptor substrate 1 19.70 Evidence
RPS6KA2 DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 19.70 Evidence
RPS6KA2 LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 19.70 Evidence
RPS6KA2 GAB1 GAB1: GRB2-associated-binding protein 1 19.70 Evidence
RPS6KA2 PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 17.60 Evidence
RPS6KA2 PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 17.60 Evidence
RPS6KA2 LYN LYN: Tyrosine-protein kinase Lyn 17.60 Evidence
RPS6KA2 STMN1 STMN1, LAP18, OP18: Stathmin 17.60 Evidence
RPS6KA2 SYK SYK: Tyrosine-protein kinase SYK 17.60 Evidence
RPS6KA2 BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 17.60 Evidence
RPS6KA2 PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 17.60 Evidence
RPS6KA2 ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 17.60 Evidence
RPS6KA2 SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 17.60 Evidence
RPS6KA2 STMN2 STMN2, SCG10, SCGN10: Stathmin-2 17.60 Evidence
RPS6KA2 STAT3 17.60 Evidence
RPS6KA2 PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 13.00 Evidence
RPS6KA2 PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 13.00 Evidence
RPS6KA2 PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 13.00 Evidence
RPS6KA2 HSF1 HSF1, HSTF1: Heat shock factor protein 1 10.30 Evidence
RPS6KA2 JUN JUN: Transcription factor AP-1 10.30 Evidence
RPS6KA2 MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 9.96 Evidence
RPS6KA2 RAB4A N/A 9.96 Evidence
RPS6KA2 CASP9 CASP9, MCH6: Caspase-9 precursor 9.96 Evidence
RPS6KA2 PEA15 PEA15: Astrocytic phosphoprotein PEA-15 9.96 Evidence
RPS6KA2 MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 9.96 Evidence
RPS6KA2 HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 8.92 Evidence
RPS6KA2 ETS1 ETS1, EWSR2: Protein C-ets-1 8.92 Evidence
RPS6KA2 DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 8.92 Evidence
RPS6KA2 ELK1 ELK1: ETS domain-containing protein Elk-1 8.92 Evidence
RPS6KA2 IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 8.92 Evidence
RPS6KA2 JUND JUND: Transcription factor jun-D 8.92 Evidence
RPS6KA2 CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 8.92 Evidence
RPS6KA2 PRKCE PRKCE, PKCE: Protein kinase C epsilon type 8.92 Evidence
RPS6KA2 PTPRA N/A 7.14 Evidence
RPS6KA2 GJA1 GJA1, GJAL: Gap junction alpha-1 protein 7.14 Evidence
RPS6KA2 TH TH, TYH: Tyrosine 3-monooxygenase 6.39 Evidence
RPS6KA2 MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 6.24 Evidence
RPS6KA2 AMPH AMPH, AMPH1: Amphiphysin 6.24 Evidence
RPS6KA2 EPOR EPOR: Erythropoietin receptor precursor 5.87 Evidence
RPS6KA2 NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 5.87 Evidence
RPS6KA2 CD44 N/A 5.87 Evidence
RPS6KA2 TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 5.59 Evidence
RPS6KA2 ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 5.26 Evidence
RPS6KA2 ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 5.26 Evidence
RPS6KA2 C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 4.19 Evidence
RPS6KA2 BCL2 BCL2: Apoptosis regulator Bcl-2 4.03 Evidence
RPS6KA2 KRT8 KRT8, CYK8: Keratin, type II cytoskeletal 8 4.03 Evidence
RPS6KA2 DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 3.70 Evidence
RPS6KA2 OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 3.70 Evidence
RPS6KA2 TOB1 TOB1, TOB, TROB1: Protein Tob1 3.63 Evidence
RPS6KA2 BTG1 BTG1: Protein BTG1 3.63 Evidence
RPS6KA2 TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 3.47 Evidence
RPS6KA2 MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 3.47 Evidence
RPS6KA2 RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 3.47 Evidence
RPS6KA2 MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 3.47 Evidence
RPS6KA2 MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 3.34 Evidence
RPS6KA2 NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 3.34 Evidence
RPS6KA2 PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 3.34 Evidence
RPS6KA2 RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 3.34 Evidence
RPS6KA2 TOP2B N/A 3.34 Evidence
RPS6KA2 UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 3.34 Evidence
RPS6KA2 PTPN7 N/A 3.34 Evidence
RPS6KA2 ESR1 ESR1, ESR, NR3A1: Estrogen receptor 3.34 Evidence
RPS6KA2 DUSP4 DUSP4, MKP2, VH2: Dual specificity protein phosphatase 4 3.31 Evidence
RPS6KA2 DUSP2 DUSP2, PAC1: Dual specificity protein phosphatase 2 3.31 Evidence
RPS6KA2 ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 3.18 Evidence
RPS6KA2 HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 2.99 Evidence
RPS6KA2 MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 2.99 Evidence
RPS6KA2 SORBS3 SORBS3, SCAM1: Vinexin 2.99 Evidence
RPS6KA2 TP53 TP53, P53: Cellular tumor antigen p53 2.99 Evidence
RPS6KA2 FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 2.99 Evidence
RPS6KA2 MAP2K3 N/A 2.99 Evidence
RPS6KA2 RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 2.99 Evidence
RPS6KA2 TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 2.99 Evidence
RPS6KA2 RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 2.99 Evidence
RPS6KA2 TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 2.99 Evidence
RPS6KA2 HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 2.99 Evidence
RPS6KA2 MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 2.99 Evidence
RPS6KA2 PTPN11 N/A 2.99 Evidence
RPS6KA2 SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 2.99 Evidence
RPS6KA2 CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 2.93 Evidence
RPS6KA2 PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 2.93 Evidence