Predicted interactions involving protein TP53, P53: Cellular tumor antigen p53 (NP_000537) that score above 1.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
TP53 H2AFX H2AFX, H2AX: Histone H2A.x 510.0 Evidence
TP53 H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 304.0 Evidence
TP53 SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 98.10 Evidence
TP53 HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 84.00 Evidence
TP53 NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 82.10 Evidence
TP53 BARD1 BARD1: BRCA1-associated RING domain protein 1 59.60 Evidence
TP53 MCM3 MCM3: DNA replication licensing factor MCM3 46.90 Evidence
TP53 BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 36.00 Evidence
TP53 CCNB1 Cyclin B1 35.00 Evidence
TP53 HSF1 HSF1, HSTF1: Heat shock factor protein 1 33.90 Evidence
TP53 EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 33.40 Evidence
TP53 MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 28.80 Evidence
TP53 SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 20.20 Evidence
TP53 STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 17.00 Evidence
TP53 EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 14.00 Evidence
TP53 STAT6 STAT6: Signal transducer and activator of transcription 6 13.20 Evidence
TP53 RELA RELA, NFKB3: Transcription factor p65 12.60 Evidence
TP53 PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 12.5 Evidence
TP53 NUP153 N/A 11.70 Evidence
TP53 RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 10.30 Evidence
TP53 SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 10.30 Evidence
TP53 MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 10.30 Evidence
TP53 CREBBP CREBBP, CBP: CREB-binding protein 10.30 Evidence
TP53 KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 10.00 Evidence
TP53 DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 9.55 Evidence
TP53 TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 9.32 Evidence
TP53 CDK7 CDK7, MO15: Cell division protein kinase 7 9.32 Evidence
TP53 RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 9.17 Evidence
TP53 DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 8.92 Evidence
TP53 DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 8.92 Evidence
TP53 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 8.00 Evidence
TP53 HDAC2 HDAC2: Histone deacetylase 2 7.52 Evidence
TP53 RBL1 RBL1: Retinoblastoma-like protein 1 6.80 Evidence
TP53 GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 6.27 Evidence
TP53 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 5.86 Evidence
TP53 SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 5.59 Evidence
TP53 RPA1 RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit 4.84 Evidence
TP53 EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 4.13 Evidence
TP53 MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 3.85 Evidence
TP53 RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 3.85 Evidence
TP53 LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 3.64 Evidence
TP53 CSNK2B CSNK2B, CK2N, G5A: Casein kinase II subunit beta 3.11 Evidence
TP53 RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 3.07 Evidence
TP53 MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 2.99 Evidence
TP53 LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 2.99 Evidence
TP53 CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 2.99 Evidence
TP53 RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 2.99 Evidence
TP53 JUN JUN: Transcription factor AP-1 2.23 Evidence
TP53 HIST1H1E HIST1H1E, H1F4: Histone H1.4 1.80 Evidence
TP53 DUSP2 DUSP2, PAC1: Dual specificity protein phosphatase 2 1.62 Evidence
TP53 CKS1B CKS1B, CKS1, PNAS-16, PNAS-143: Cyclin-dependent kinases regulatory subunit 1 1.37 Evidence
TP53 NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 1.37 Evidence
TP53 HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 1.37 Evidence
TP53 SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 1.37 Evidence
TP53 RELB RELB: Transcription factor RelB 1.24 Evidence
TP53 HIST1H1B HIST1H1B, H1F5: Histone H1.5 1.09 Evidence